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Volumn 134, Issue 8, 2014, Pages 2080-2085

UV signaling pathways within the skin

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE ACTIVATOR; ALPHA INTERMEDIN; CARCINOGEN; EUMELANIN; HISTONE DEACETYLASE INHIBITOR; MELANOCORTIN 1 RECEPTOR; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PHEOMELANIN; PHOSPHODIESTERASE IV INHIBITOR; SUNSCREEN;

EID: 84904500842     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.161     Document Type: Review
Times cited : (125)

References (47)
  • 1
    • 33845610991 scopus 로고    scopus 로고
    • T-oligos augment UV-induced protective responses in human skin
    • Arad S, Konnikov N, Goukassian DA et al. (2006) T-oligos augment UV-induced protective responses in human skin. FASEB J 20:1895-7
    • (2006) FASEB J , vol.20 , pp. 1895-1897
    • Arad, S.1    Konnikov, N.2    Goukassian, D.A.3
  • 2
    • 34447500134 scopus 로고    scopus 로고
    • Oligonucleotide treatment increases eumelanogenesis, hair pigmentation andmelanocortin-1 receptor expression in the hair follicle
    • Atoyan RY, Sharov AA, Eller MS et al. (2007) Oligonucleotide treatment increases eumelanogenesis, hair pigmentation andmelanocortin-1 receptor expression in the hair follicle. Exp Dermatol 16:671-7
    • (2007) Exp Dermatol , vol.16 , pp. 671-677
    • Atoyan, R.Y.1    Sharov, A.A.2    Eller, M.S.3
  • 4
    • 82555205202 scopus 로고    scopus 로고
    • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
    • Bertolotto C, Lesueur F, Giuliano S et al. (2011) A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature 480:94-8
    • (2011) Nature , vol.480 , pp. 94-98
    • Bertolotto, C.1    Lesueur, F.2    Giuliano, S.3
  • 5
    • 49149102585 scopus 로고    scopus 로고
    • Sunlight ultraviolet irradiation and BRAF V600 mutagenesis in human melanoma
    • Besaratinia A, Pfeifer GP (2008) Sunlight ultraviolet irradiation and BRAF V600 mutagenesis in human melanoma. Hum Mutat 29:983-91
    • (2008) Hum Mutat , vol.29 , pp. 983-991
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 6
    • 33847422145 scopus 로고    scopus 로고
    • Central role of p53 in the suntan response and pathologic hyperpigmentation
    • Cui R, Widlund HR, Feige E et al. (2007) Central role of p53 in the suntan response and pathologic hyperpigmentation. Cell 128:853-64
    • (2007) Cell , vol.128 , pp. 853-864
    • Cui, R.1    Widlund, H.R.2    Feige, E.3
  • 8
    • 33748920021 scopus 로고    scopus 로고
    • Topical drug rescue strategy and skin protection based on the role of Mc1r inUV-induced tanning
    • D'Orazio JA, Nobuhisa T, Cui R et al. (2006) Topical drug rescue strategy and skin protection based on the role of Mc1r inUV-induced tanning. Nature 443:340-4
    • (2006) Nature , vol.443 , pp. 340-344
    • D'Orazio, J.A.1    Nobuhisa, T.2    Cui, R.3
  • 9
    • 0028934354 scopus 로고
    • Mutation spectra in Salmonella of sunlight, white fluorescent light, and lightfrom tanning salon beds: Induction of tandem mutations and role of DNA repair
    • DeMarini DM, Shelton ML, Stankowski LF Jr (1995) Mutation spectra in Salmonella of sunlight, white fluorescent light, and lightfrom tanning salon beds: Induction of tandem mutations and role of DNA repair. Mutat Res 327:131-49
    • (1995) Mutat Res , vol.327 , pp. 131-149
    • Demarini, D.M.1    Shelton, M.L.2    Stankowski Jr., L.F.3
  • 10
    • 77951667623 scopus 로고    scopus 로고
    • MC1R variants increase melanoma risk in families with CDKN2A mutations: Ameta-analysis
    • Fargnoli MC, Gandini S, Peris K et al. (2010) MC1R variants increase melanoma risk in families with CDKN2A mutations: Ameta-analysis. Eur J Cancer 46:1413-20
    • (2010) Eur J Cancer , vol.46 , pp. 1413-1420
    • Fargnoli, M.C.1    Gandini, S.2    Peris, K.3
  • 11
    • 77956275516 scopus 로고    scopus 로고
    • Indoor tanning-science, behavior, and policy
    • Fisher DE, James WD (2010) Indoor tanning-science, behavior, and policy. N Engl J Med 363:901-3
    • (2010) N Engl J Med , vol.363 , pp. 901-903
    • Fisher, D.E.1    James, W.D.2
  • 12
    • 84860214530 scopus 로고    scopus 로고
    • From genes to drugs: Targeted strategies for melanoma
    • Flaherty KT, Hodi FS, Fisher DE (2012) From genes to drugs: Targeted strategies for melanoma. Nat Rev Cancer 12:349-61
    • (2012) Nat Rev Cancer , vol.12 , pp. 349-361
    • Flaherty, K.T.1    Hodi, F.S.2    Fisher, D.E.3
  • 13
    • 77956266528 scopus 로고    scopus 로고
    • How sunlight causes melanoma
    • Garibyan L, Fisher DE (2010) How sunlight causes melanoma. Curr Oncol Rep 12:319-26
    • (2010) Curr Oncol Rep , vol.12 , pp. 319-326
    • Garibyan, L.1    Fisher, D.E.2
  • 15
    • 0031609839 scopus 로고    scopus 로고
    • Discovery and development of novel melanogenic drugs. Melanotan-I and-II
    • Hadley ME, Hruby VJ, Blanchard J et al. (1998) Discovery and development of novel melanogenic drugs. Melanotan-I and-II. Pharm Biotechnol 11:575-95
    • (1998) Pharm Biotechnol , vol.11 , pp. 575-595
    • Hadley, M.E.1    Hruby, V.J.2    Blanchard, J.3
  • 16
    • 33748503917 scopus 로고    scopus 로고
    • Melanocortin 1 receptor variants and skin cancer risk
    • Han J, Kraft P, Colditz GA et al. (2006) Melanocortin 1 receptor variants and skin cancer risk. Int J Cancer 119:1976-84
    • (2006) Int J Cancer , vol.119 , pp. 1976-1984
    • Han, J.1    Kraft, P.2    Colditz, G.A.3
  • 17
    • 33745757131 scopus 로고    scopus 로고
    • Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes
    • Hauser JE, Kadekaro AL, Kavanagh R et al. (2006) Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Melanoma Res 19:303-14
    • (2006) Pigment Cell Melanoma Res , vol.19 , pp. 303-314
    • Hauser, J.E.1    Kadekaro, A.L.2    Kavanagh, R.3
  • 18
    • 84856147809 scopus 로고    scopus 로고
    • Determination of melanin synthetic pathways
    • Hearing VJ (2011a) Determination of melanin synthetic pathways. J Invest Dermatol 131:E8-11
    • (2011) J Invest Dermatol , vol.131
    • Hearing, V.J.1
  • 19
    • 84856168389 scopus 로고    scopus 로고
    • Milestones in melanocytes/melanogenesis
    • Hearing VJ (2011b) Milestones in melanocytes/melanogenesis. J Invest Dermatol 131:E1
    • (2011) J Invest Dermatol , vol.131
    • Hearing, V.J.1
  • 20
    • 0032518262 scopus 로고    scopus 로고
    • MAP kinase links the transcription factor microphthalmia to c-Kit signaling in melanocytes
    • Hemesath TJ, Price ER, Takemoto C et al. (1998) MAP kinase links the transcription factor microphthalmia to c-Kit signaling in melanocytes. Nature 391:298-301
    • (1998) Nature , vol.391 , pp. 298-301
    • Hemesath, T.J.1    Price, E.R.2    Takemoto, C.3
  • 21
    • 20144377250 scopus 로고    scopus 로고
    • A-Melanocortin and endothelin-1 activate anti-apoptotic pathways and reduce DNA damage in human melanocytes
    • Kadekaro AL, Kavanagh R, Kanto H et al. (2005) a-Melanocortin and endothelin-1 activate anti-apoptotic pathways and reduce DNA damage in human melanocytes. Cancer Res 65:4292-9
    • (2005) Cancer Res , vol.65 , pp. 4292-4299
    • Kadekaro, A.L.1    Kavanagh, R.2    Kanto, H.3
  • 22
    • 77958617776 scopus 로고    scopus 로고
    • Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit
    • Khaled M, Levy C, Fisher DE (2010) Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit. Genes Dev 24:2276-81
    • (2010) Genes Dev , vol.24 , pp. 2276-2281
    • Khaled, M.1    Levy, C.2    Fisher, D.E.3
  • 23
    • 77955889534 scopus 로고    scopus 로고
    • Melanotropic peptides: More than just 'Barbie drugs' and 'sun-tan jabs'
    • Langan EA, Nie Z, Rhodes LE (2010) Melanotropic peptides: More than just 'Barbie drugs' and 'sun-tan jabs'. Br J Dermatol 163:451-5
    • (2010) Br J Dermatol , vol.163 , pp. 451-455
    • Langan, E.A.1    Nie, Z.2    Rhodes, L.E.3
  • 24
    • 27944444538 scopus 로고    scopus 로고
    • The indoor UV tanning industry: A review of skin cancer risk, health benefit claims, and regulation
    • Levine JA, Sorace M, Spencer J et al. (2005) The indoor UV tanning industry: A review of skin cancer risk, health benefit claims, and regulation. J Am Acad Dermatol 53:1038-44
    • (2005) J Am Acad Dermatol , vol.53 , pp. 1038-1044
    • Levine, J.A.1    Sorace, M.2    Spencer, J.3
  • 25
    • 33747882661 scopus 로고    scopus 로고
    • MITF: Master regulator of melanocyte development and melanoma oncogene
    • Levy C, Khaled M, Fisher DE (2006) MITF: Master regulator of melanocyte development and melanoma oncogene. Trends Mol Med 12:406-14
    • (2006) Trends Mol Med , vol.12 , pp. 406-414
    • Levy, C.1    Khaled, M.2    Fisher, D.E.3
  • 26
    • 84863712468 scopus 로고    scopus 로고
    • YY1 regulates melanocyte development and function by cooperating with MITF
    • Li J, Song JS, Bell RJ et al. (2012) YY1 regulates melanocyte development and function by cooperating with MITF. PLoS Genet 8:e1002688
    • (2012) PLoS Genet , vol.8
    • Li, J.1    Song, J.S.2    Bell, R.J.3
  • 27
    • 78049248595 scopus 로고    scopus 로고
    • Lighting a path to pigmentation: Mechanisms of MITF induction by UV
    • Liu JJ, Fisher DE (2010) Lighting a path to pigmentation: Mechanisms of MITF induction by UV. Pigment Cell Melanoma Res 23:741-5
    • (2010) Pigment Cell Melanoma Res , vol.23 , pp. 741-745
    • Liu, J.J.1    Fisher, D.E.2
  • 28
    • 84883477049 scopus 로고    scopus 로고
    • BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage
    • Mar VJ, Wong SQ, Li J et al. (2013) BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage. Clin Cancer Res 19:4589-98
    • (2013) Clin Cancer Res , vol.19 , pp. 4589-4598
    • Mar, V.J.1    Wong, S.Q.2    Li, J.3
  • 29
    • 25444527174 scopus 로고    scopus 로고
    • T-oligo treatment decreases constitutive and UVB-induced COX-2 levels throughp53-and NFkappaBdependent repression of the COX-2 promoter
    • Marwaha V, Chen YH, Helms E et al. (2005) T-oligo treatment decreases constitutive and UVB-induced COX-2 levels throughp53-and NFkappaBdependent repression of the COX-2 promoter. J Biol Chem280:32379-88
    • (2005) J Biol Chem , vol.280 , pp. 32379-32388
    • Marwaha, V.1    Chen, Y.H.2    Helms, E.3
  • 30
    • 12844268574 scopus 로고    scopus 로고
    • Sumoylation of MITF and its related family members TFE3 and TFEB
    • Miller AJ, Levy C, Davis IJ et al. (2005) Sumoylation of MITF and its related family members TFE3 and TFEB. J Biol Chem 280:146-55
    • (2005) J Biol Chem , vol.280 , pp. 146-155
    • Miller, A.J.1    Levy, C.2    Davis, I.J.3
  • 31
    • 72749105197 scopus 로고    scopus 로고
    • New insights into pigmentary pathways and skin cancer
    • Iller AJ,Tsao H (2010) New insights into pigmentary pathways and skin cancer. Br J Dermatol 162, 22-8
    • (2010) Br J Dermatol , vol.162 , pp. 22-28
    • Iller, A.J.1    Tsao, H.2
  • 32
    • 84869084595 scopus 로고    scopus 로고
    • An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in thered hair/fair skin background
    • Mitra D, Luo X, Morgan A et al. (2012) An ultraviolet-radiation- independent pathway to melanoma carcinogenesis in thered hair/fair skin background. Nature 491:449-53
    • (2012) Nature , vol.491 , pp. 449-453
    • Mitra, D.1    Luo, X.2    Morgan, A.3
  • 33
    • 84880329037 scopus 로고    scopus 로고
    • How does pheomelanin synthesis contribute to melanomagenesis: Two distinctmechanisms could explain the carcinogenicity of pheomelanin synthesis
    • Morgan AM, Lo J, Fisher DE (2013) How does pheomelanin synthesis contribute to melanomagenesis: Two distinctmechanisms could explain the carcinogenicity of pheomelanin synthesis. Bioessays 35:672-6
    • (2013) Bioessays , vol.35 , pp. 672-676
    • Morgan, A.M.1    Lo, J.2    Fisher, D.E.3
  • 34
    • 62349102441 scopus 로고    scopus 로고
    • Indoor ultraviolet tanning and skin cancer: Health risks and opportunities
    • Schulman JM, Fisher DE (2009) Indoor ultraviolet tanning and skin cancer: Health risks and opportunities. Curr Opin Oncol 21:144-9
    • (2009) Curr Opin Oncol , vol.21 , pp. 144-149
    • Schulman, J.M.1    Fisher, D.E.2
  • 35
    • 84897533005 scopus 로고    scopus 로고
    • Eruptive naevi and darkening of pre-existing naevi 24h after a single mono-dose injection of melanotan II
    • Schulze F, Erdmann H, Hardkop LH et al. (2013) Eruptive naevi and darkening of pre-existing naevi 24h after a single mono-dose injection of melanotan II. Eur J Dermatol 24:107-9
    • (2013) Eur J Dermatol , vol.24 , pp. 107-109
    • Schulze, F.1    Erdmann, H.2    Hardkop, L.H.3
  • 36
    • 84872276087 scopus 로고    scopus 로고
    • PGC-1 coactivators regulate MITF and the tanning response
    • Shoag J, Haq R, Zhang M et al. (2013) PGC-1 coactivators regulate MITF and the tanning response. Mol Cell 49:145-57
    • (2013) Mol Cell , vol.49 , pp. 145-157
    • Shoag, J.1    Haq, R.2    Zhang, M.3
  • 37
    • 0033694888 scopus 로고    scopus 로고
    • Neuroendocrinology of the skin
    • Slominski A, Wortsman J (2000) Neuroendocrinology of the skin. Endocr Rev 21:457-87
    • (2000) Endocr Rev , vol.21 , pp. 457-487
    • Slominski, A.1    Wortsman, J.2
  • 38
    • 33847064628 scopus 로고    scopus 로고
    • Differential expression of HPA axis homolog in the skin
    • Slominski A, Wortsman J, Tuckey RC et al. (2007) Differential expression of HPA axis homolog in the skin. Mol Cell Endocrinol 265-266:143-9
    • (2007) Mol Cell Endocrinol , vol.265-266 , pp. 143-149
    • Slominski, A.1    Wortsman, J.2    Tuckey, R.C.3
  • 39
    • 84862848789 scopus 로고    scopus 로고
    • Sensing the environment: Regulation of local and global homeostasis by the skin'sneuroendocrine system
    • Slominski AT, Zmijewski MA, Skobowiat C et al. (2012) Sensing the environment: Regulation of local and global homeostasis by the skin'sneuroendocrine system. Adv Anat Embryol Cell Biol 212, v, vii1-115
    • (2012) Adv Anat Embryol Cell Biol , vol.212 , Issue.1
    • Slominski, A.T.1    Zmijewski, M.A.2    Skobowiat, C.3
  • 40
    • 33746105691 scopus 로고    scopus 로고
    • Could BRAF mutations in melanocytic lesions arise from DNA damage induced byultraviolet radiation
    • Thomas NE, Berwick M, Cordeiro-Stone M (2006) Could BRAF mutations in melanocytic lesions arise from DNA damage induced byultraviolet radiation. J Invest Dermatol 126:1693-6
    • (2006) J Invest Dermatol , vol.126 , pp. 1693-1696
    • Thomas, N.E.1    Berwick, M.2    Cordeiro-Stone, M.3
  • 41
    • 52149115782 scopus 로고    scopus 로고
    • UV and pigmentation: Molecular mechanisms and social controversies
    • Tran TT, Schulman J, Fisher DE (2008) UV and pigmentation: Molecular mechanisms and social controversies. Pigment Cell Melanoma Res 21:509-16
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 509-516
    • Tran, T.T.1    Schulman, J.2    Fisher, D.E.3
  • 42
    • 84884183582 scopus 로고    scopus 로고
    • Epidemiology and UV exposure
    • Weinstock MA (2013) Epidemiology and UV exposure. J Invest Dermatol 133:E11-2
    • (2013) J Invest Dermatol , vol.133
    • Weinstock, M.A.1
  • 43
    • 0034142326 scopus 로고    scopus 로고
    • C-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi
    • Wu M, Hemesath TJ, Takemoto CM et al. (2000) c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi. Genes Dev 14:301-12
    • (2000) Genes Dev , vol.14 , pp. 301-312
    • Wu, M.1    Hemesath, T.J.2    Takemoto, C.M.3
  • 44
    • 47249113549 scopus 로고    scopus 로고
    • Pharmacologic suppression of MITF expression via HDAC inhibitors in themelanocyte lineage
    • Yokoyama S, Feige E, Poling LL et al. (2008) Pharmacologic suppression of MITF expression via HDAC inhibitors in themelanocyte lineage. Pigment Cell Melanoma Res 21:457-63
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 457-463
    • Yokoyama, S.1    Feige, E.2    Poling, L.L.3
  • 45
    • 82555187007 scopus 로고    scopus 로고
    • A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
    • Yokoyama S, Woods SL, Boyle GM et al. (2011) A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature 480:99-103
    • (2011) Nature , vol.480 , pp. 99-103
    • Yokoyama, S.1    Woods, S.L.2    Boyle, G.M.3
  • 46
    • 33749347593 scopus 로고    scopus 로고
    • Characterization of a ultraviolet B-induced corticotropin- releasinghormone-proopiomelanocortin system in human melanocytes
    • Zbytek B, Wortsman J, Slominski A (2006) Characterization of a ultraviolet B-induced corticotropin-releasinghormone-proopiomelanocortin system in human melanocytes. Mol Endocrinol 20:2539-47
    • (2006) Mol Endocrinol , vol.20 , pp. 2539-2547
    • Zbytek, B.1    Wortsman, J.2    Slominski, A.3
  • 47
    • 79961200772 scopus 로고    scopus 로고
    • Regulation of MITF stability by the USP13 deubiquitinase
    • Zhao X, Fiske B, Kawakami A et al. (2011) Regulation of MITF stability by the USP13 deubiquitinase. Nat Commun 2:414
    • (2011) Nat Commun , vol.2 , pp. 414
    • Zhao, X.1    Fiske, B.2    Kawakami, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.