Computational investigation of Locked Nucleic Acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulations

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Poongavanam, Vasanthanathan ^a   Madala, Praveen K ^b   Højland, Torben ^a   Veedu, Rakesh N ^a,b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; LOCKED NUCLEIC ACID; NUCLEOTIDE; DNA DIRECTED DNA POLYMERASE; OLIGONUCLEOTIDE; POLYPHOSPHATE; TRIPHOSPHORIC ACID;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DNA CONFORMATION; DNA STRUCTURE; ENZYME ACTIVE SITE; HYDROGEN BOND; MOLECULAR DOCKING; SIMULATION; STEREOCHEMISTRY; CHEMISTRY; CONFORMATION; METABOLISM;

CATALYTIC DOMAIN; DNA-DIRECTED DNA POLYMERASE; MOLECULAR DOCKING SIMULATION; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; POLYPHOSPHATES;

EID: 84904480199     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102126     Document Type: Article

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