메뉴 건너뛰기




Volumn 13, Issue 8, 2014, Pages 1031-1042

Safety of antipsychotic drugs: Focus on therapeutic and adverse effects

Author keywords

Aripiprazole; Asenapine; Cariprazine; Clinical trial; Clozapine; Lurasidone; Olanzapine; Paliperidone; Quetiapine; Risperidone; Side effects; Tolerability; Ziprasidone

Indexed keywords

ARIPIPRAZOLE; ASENAPINE; CARIPRAZINE; CLOZAPINE; HALOPERIDOL; LURASIDONE; NEUROLEPTIC AGENT; OLANZAPINE; PALIPERIDONE; QUETIAPINE; RISPERIDONE; ZIPRASIDONE; BENZODIAZEPINE DERIVATIVE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; SEROTONIN 2 ANTAGONIST;

EID: 84904473696     PISSN: 14740338     EISSN: 1744764X     Source Type: Journal    
DOI: 10.1517/14740338.2014.935761     Document Type: Review
Times cited : (59)

References (46)
  • 1
    • 50149100882 scopus 로고    scopus 로고
    • Indicated prevention of schizophrenia
    • Klosterkoetter J. Indicated prevention of schizophrenia. Dtsch Arztebl Int 2008;105:532-9
    • (2008) Dtsch Arztebl Int , vol.105 , pp. 532-539
    • Klosterkoetter, J.1
  • 2
    • 84893002219 scopus 로고    scopus 로고
    • Classical neurotransmitter and neuropeptides involved in schizophrenia: How to choose the appropriate antipsychotic drug?
    • Werner FM, Coveñas R. Classical neurotransmitter and neuropeptides involved in schizophrenia: How to choose the appropriate antipsychotic drug?. Curr Drug Ther 2013;8:132-43
    • (2013) Curr Drug Ther , vol.8 , pp. 132-143
    • Werner, F.M.1    Coveñas, R.2
  • 3
    • 84877811965 scopus 로고    scopus 로고
    • Movement disorders in elderly users of risperidone and first generation antipsychotic agents: A Canadian population-based study
    • Vasilyeva I, Biscontri RG, Enns MW, et al. Movement disorders in elderly users of risperidone and first generation antipsychotic agents: A Canadian population-based study. PLoS One 2013;8:e64217
    • (2013) PLoS One , vol.8
    • Vasilyeva, I.1    Biscontri, R.G.2    Enns, M.W.3
  • 4
    • 84864018543 scopus 로고    scopus 로고
    • Pharmacological treatment of firsteipsode schizophrenia: A review of the literature
    • Thomas SP, Nandhra HS, Singh SP. Pharmacological treatment of firsteipsode schizophrenia: A review of the literature. Prim Care Companion CNS Disord 2012;14:PCC.11r01198
    • (2012) Prim Care Companion CNS Disord , vol.14
    • Thomas, S.P.1    Nandhra, H.S.2    Singh, S.P.3
  • 5
    • 84871102775 scopus 로고    scopus 로고
    • Summary of the comparative effectiveness review on off-label use of atypical antipsychotics
    • Maher AR, Theodore G. Summary of the comparative effectiveness review on off-label use of atypical antipsychotics. J Manag Care Pharm 2012;18:S1-20
    • (2012) J Manag Care Pharm , vol.18
    • Maher, A.R.1    Theodore, G.2
  • 6
    • 84856089041 scopus 로고    scopus 로고
    • Asenapine effects on cognitive and monamine dysfunction elicited by subchronic phencyclidine administration
    • Elsworth JD, Groman SM, Jentsch JD, et al. Asenapine effects on cognitive and monamine dysfunction elicited by subchronic phencyclidine administration. Neuropsychopharmacology 2011;62:1442-52
    • (2011) Neuropsychopharmacology , vol.62 , pp. 1442-1452
    • Elsworth, J.D.1    Groman, S.M.2    Jentsch, J.D.3
  • 7
    • 77649197551 scopus 로고    scopus 로고
    • Tratamientos para la esquizofrenia. Revisión crítica sobre la farmacología y mecanismos De acción De los antipsicó ticos
    • Tajima K, Fernández H, López-Ibor JJ, et al. Tratamientos para la esquizofrenia. Revisión crítica sobre la farmacología y mecanismos De acción De los antipsicóticos. Actas Esp Psiquiatr 2009;37:330-42
    • (2009) Actas Esp Psiquiatr , vol.37 , pp. 330-342
    • Tajima, K.1    Fernández, H.2    López-Ibor, J.J.3
  • 8
    • 84875270413 scopus 로고    scopus 로고
    • Lurasidone for the treatment of acutely psychotic patients with schizophrenia: A 6-week, randomized, placebo-controlled study
    • Nasrallah HA, Silva R, Philipps D, et al. Lurasidone for the treatment of acutely psychotic patients with schizophrenia: A 6-week, randomized, placebo-controlled study. J Psychiatr Res 2013;47:670-7
    • (2013) J Psychiatr Res , vol.47 , pp. 670-677
    • Nasrallah, H.A.1    Silva, R.2    Philipps, D.3
  • 9
    • 84881562922 scopus 로고    scopus 로고
    • A new generation of antipsychotics: Pharmacology and clinical utility of cariprazine in schizophrenia
    • Caccia S, Invernizzi RW, Nobili A, et al. A new generation of antipsychotics: Pharmacology and clinical utility of cariprazine in schizophrenia. Ther Clin Risk Manag 2013;9:319-28
    • (2013) Ther Clin Risk Manag , vol.9 , pp. 319-328
    • Caccia, S.1    Invernizzi, R.W.2    Nobili, A.3
  • 10
    • 84878245007 scopus 로고    scopus 로고
    • Effectiveness of lurasidone for patients with schizophrenia following 6 weeks of acute treatment with lurasidone, olanzapine, or placebo: A 6-month, open-label, extension study
    • Stahl SM, Cucchiaro J, Simonelli D, et al. Effectiveness of lurasidone for patients with schizophrenia following 6 weeks of acute treatment with lurasidone, olanzapine, or placebo: A 6-month, open-label, extension study. J Clin Psychiatry 2013;74:507-15
    • (2013) J Clin Psychiatry , vol.74 , pp. 507-515
    • Stahl, S.M.1    Cucchiaro, J.2    Simonelli, D.3
  • 11
    • 84875413162 scopus 로고    scopus 로고
    • Long-Acting injectable antipsychotics and the development of postinjection delirium/sedation syndrome (PDSS
    • Novakovic V, Adel T, Peselow E, et al. Long-Acting injectable antipsychotics and the development of postinjection delirium/sedation syndrome (PDSS). Clin Neuropharmacol 2013;36:59-62
    • (2013) Clin Neuropharmacol , vol.36 , pp. 59-62
    • Novakovic, V.1    Adel, T.2    Peselow, E.3
  • 12
    • 84863698892 scopus 로고    scopus 로고
    • Adverse effects of cognitive behavioural therapy and cognitive remediation in schizophrenia: Results of the treatment of negative symptoms study
    • Klingberg S, Herrlich J, Wiedemann G, et al. Adverse effects of cognitive behavioural therapy and cognitive remediation in schizophrenia: Results of the treatment of negative symptoms study. J Nerv Ment Dis 2012;200:569-76
    • (2012) J Nerv Ment Dis , vol.200 , pp. 569-576
    • Klingberg, S.1    Herrlich, J.2    Wiedemann, G.3
  • 13
    • 84875951909 scopus 로고    scopus 로고
    • Pharmacokineticpharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia part I: The use of PANSS total score and clinical utility
    • Venkatesh PR, Kozielska M, Suleiman AA, et al. Pharmacokineticpharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia part I: The use of PANSS total score and clinical utility. Schizophr Res 2013;146:146-52
    • (2013) Schizophr Res , vol.146 , pp. 146-152
    • Venkatesh, P.R.1    Kozielska, M.2    Suleiman, A.A.3
  • 14
    • 84875961054 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia part II: The use of subscales of the PANSS score
    • Venkatesh PR, Kozielska M, Suleiman AA, et al. Pharmacokinetic- pharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia part II: The use of subscales of the PANSS score. Schizophr Res 2013;146:153-61
    • (2013) Schizophr Res , vol.146 , pp. 153-161
    • Venkatesh, P.R.1    Kozielska, M.2    Suleiman, A.A.3
  • 15
    • 84862545039 scopus 로고    scopus 로고
    • Oral paliperidone extendedrelease: Chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability
    • Citrome L. Oral paliperidone extendedrelease: Chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability. Expert Opin Drug Metab Toxicol 2012;8:873-88
    • (2012) Expert Opin Drug Metab Toxicol , vol.8 , pp. 873-888
    • Citrome, L.1
  • 16
    • 84888989285 scopus 로고    scopus 로고
    • Efficacy and tolerability of quetiapine versus haloperidol in first-episode schizophrenia: A randomized clinical trial
    • 6 and 12 weeks
    • Amr M, Lakhan SE, Sanhan S, et al. Efficacy and tolerability of quetiapine versus haloperidol in first-episode schizophrenia: A randomized clinical trial. Int Arch Med 2013;6:47 6 and 12 weeks
    • (2013) Int Arch Med , vol.6 , Issue.47
    • Amr, M.1    Lakhan, S.E.2    Sanhan, S.3
  • 17
    • 84901392885 scopus 로고    scopus 로고
    • Population pharmacokinetic/ pharmacodynamic model for clozapine for characterising the relationship between accumulated exposure and PANSS scores in patients with schizophrenia
    • Shang DW, Li LJ, Wang XP, et al. Population pharmacokinetic/ pharmacodynamic model for clozapine for characterising the relationship between accumulated exposure and PANSS scores in patients with schizophrenia. Ther Drug Monit 2014;36(3):378-86
    • (2014) Ther Drug Monit , vol.36 , Issue.3 , pp. 378-386
    • Shang, D.W.1    Li, L.J.2    Wang, X.P.3
  • 18
    • 84903815492 scopus 로고    scopus 로고
    • Aripiprazole versus other antipsychotics for schizophrenia
    • Khanna P, Suo T, Komossa K, et al. Aripiprazole versus other antipsychotics for schizophrenia. Cochrane Database Syst Rev 2014;1:CD006569
    • (2014) Cochrane Database Syst Rev , vol.1
    • Khanna, P.1    Suo, T.2    Komossa, K.3
  • 19
    • 84880476080 scopus 로고    scopus 로고
    • Antipsychotic-induced sexual dysfunction and its management
    • Park YW, Kim Y, Lee JH. Antipsychotic-induced sexual dysfunction and its management. World J Mens Health 2012;30:153-9
    • (2012) World J Mens Health , vol.30 , pp. 153-159
    • Park, Y.W.1    Kim, Y.2    Lee, J.H.3
  • 20
    • 84906789910 scopus 로고    scopus 로고
    • Effectiveness of lurasidone in schizoprenia or schizoaffective patients switched from other antipsychotic drugs: A 6-month, open-label, extension study
    • Citrome L, Weiden PJ, McEvoy JP, et al. Effectiveness of lurasidone in schizoprenia or schizoaffective patients switched from other antipsychotic drugs: A 6-month, open-label, extension study. CNS Spectr 2013;16:1-10
    • (2013) CNS Spectr , vol.16 , pp. 1-10
    • Citrome, L.1    Weiden, P.J.2    McEvoy, J.P.3
  • 21
    • 84896756353 scopus 로고    scopus 로고
    • Early improvement as a predictor of treatment response and remission in patients with schizophrenia: A pooled, post-hoc analysis from the asenapine development program
    • Leucht S, Zhao J. Early improvement as a predictor of treatment response and remission in patients with schizophrenia: A pooled, post-hoc analysis from the asenapine development program. J Psychopharmacol 2014;28:387-94
    • (2014) J Psychopharmacol , vol.28 , pp. 387-394
    • Leucht, S.1    Zhao, J.2
  • 22
    • 84886251333 scopus 로고    scopus 로고
    • Long-Term effects of asenapine in patients with persistent negative symptoms of schizophrenia: A pooled analysis
    • Potkin SG, Phiri P, Szegedi A, et al. Long-Term effects of asenapine in patients with persistent negative symptoms of schizophrenia: A pooled analysis. Schizophr Res 2013;150:442-9
    • (2013) Schizophr Res , vol.150 , pp. 442-449
    • Potkin, S.G.1    Phiri, P.2    Szegedi, A.3
  • 23
    • 84871838728 scopus 로고    scopus 로고
    • Meta-Analysis of the efficacy of asenapine for acute schizophrenia: Comparisons with placebo and other antipsychotics
    • Szegedi A, Verweij P, van Duijnhoven W, et al. Meta-Analysis of the efficacy of asenapine for acute schizophrenia: Comparisons with placebo and other antipsychotics. J Clin Psychiatry 2012;73:1533-40
    • (2012) J Clin Psychiatry , vol.73 , pp. 1533-1540
    • Szegedi, A.1    Verweij, P.2    Van Duijnhoven, W.3
  • 25
    • 84872473680 scopus 로고    scopus 로고
    • Cariprazine: Chemistry, pharmacodynamics, pharmacokinetics, and metabolism, clinical efficacy, safety and tolerability
    • Citrome L. Cariprazine: Chemistry, pharmacodynamics, pharmacokinetics, and metabolism, clinical efficacy, safety and tolerability. Expert Opin Drug Metab Toxicol 2013;9:193-206
    • (2013) Expert Opin Drug Metab Toxicol , vol.9 , pp. 193-206
    • Citrome, L.1
  • 26
    • 84891638911 scopus 로고    scopus 로고
    • Cariprazine in schizophrenia: Clinical efficacy, tolerability, and place in therapy
    • Citrome L. Cariprazine in schizophrenia: Clinical efficacy, tolerability, and place in therapy. Adv Ther 2013;30:114-26
    • (2013) Adv Ther , vol.30 , pp. 114-126
    • Citrome, L.1
  • 27
    • 84892852345 scopus 로고    scopus 로고
    • An evaluation of the safety and efficacy of cariprazine in patients with acute excacerbation of schizophrenia: A phase II randomized, clinical trial
    • Durgam S, Starace A, Li D, et al. An evaluation of the safety and efficacy of cariprazine in patients with acute excacerbation of schizophrenia: A phase II randomized, clinical trial. Schizophr Res 2014;152:450-7
    • (2014) Schizophr Res , vol.152 , pp. 450-457
    • Durgam, S.1    Starace, A.2    Li, D.3
  • 28
    • 84969293974 scopus 로고    scopus 로고
    • Possible therapeutic options in Parkinson's disease according to a neuronal network
    • Werner FM, Coveñas R. Possible therapeutic options in Parkinson's disease according to a neuronal network. Neurol Rehabil 2012;18:420-1
    • (2012) Neurol Rehabil , vol.18 , pp. 420-421
    • Werner, F.M.1    Coveñas, R.2
  • 29
    • 84878245007 scopus 로고    scopus 로고
    • Effectiveness of lurasidone for patients with schizophrenia following 6 weeks of acute treatment with lurasidone, olanzapine or placebo: A 6-month, open-label, extension study
    • Stahl SM, Cucchiaro J, Simonelli D, et al. Effectiveness of lurasidone for patients with schizophrenia following 6 weeks of acute treatment with lurasidone, olanzapine or placebo: A 6-month, open-label, extension study. J Clin Psychiatry 2013;74:507-15
    • (2013) J Clin Psychiatry , vol.74 , pp. 507-515
    • Stahl, S.M.1    Cucchiaro, J.2    Simonelli, D.3
  • 30
    • 84860741260 scopus 로고    scopus 로고
    • Asenapine: A clinical review of a second-generation antipsychotic
    • Stoner SC, Pace HA. Asenapine: A clinical review of a second-generation antipsychotic. Clin Ther 2012;34:1023-40
    • (2012) Clin Ther , vol.34 , pp. 1023-1040
    • Stoner, S.C.1    Pace, H.A.2
  • 31
    • 84874942620 scopus 로고    scopus 로고
    • Risk of cardiovascular morbidity with risperidone or paliperidone treatment: Analysis of 64 randomized, double-blind trials
    • Gopal S, Hough D, Karcher K, et al. Risk of cardiovascular morbidity with risperidone or paliperidone treatment: Analysis of 64 randomized, double-blind trials. J Clin Psychopharmacol 2013;33:157-61
    • (2013) J Clin Psychopharmacol , vol.33 , pp. 157-161
    • Gopal, S.1    Hough, D.2    Karcher, K.3
  • 32
    • 77957923642 scopus 로고    scopus 로고
    • Head-To-head comparison of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-Analysis
    • Rummel-Kluge C, Komossa K, Schwarz S, et al. Head-To-head comparison of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-Analysis. Schizophr Res 2010;123:225-33
    • (2010) Schizophr Res , vol.123 , pp. 225-233
    • Rummel-Kluge, C.1    Komossa, K.2    Schwarz, S.3
  • 33
    • 84875339034 scopus 로고    scopus 로고
    • A comparison of cardiovascular risk factors for ten antipsychotic drugs in clinical practice
    • Bodén R, Edman G, Reutfors J, et al. A comparison of cardiovascular risk factors for ten antipsychotic drugs in clinical practice. Neuropsychiatr Dis Treat 2013;9:371-7
    • (2013) Neuropsychiatr Dis Treat , vol.9 , pp. 371-377
    • Bodén, R.1    Edman, G.2    Reutfors, J.3
  • 34
    • 84898740332 scopus 로고    scopus 로고
    • Weight change and metabolic effects of asenapine in patients with schizophrenia and bipolar disorder
    • Kemp DE, Zhao J, Cazorla P, et al. Weight change and metabolic effects of asenapine in patients with schizophrenia and bipolar disorder. J Clin Psychiatry 2014;75(3):238-45
    • (2014) J Clin Psychiatry , vol.75 , Issue.3 , pp. 238-245
    • Kemp, D.E.1    Zhao, J.2    Cazorla, P.3
  • 35
    • 84911423591 scopus 로고    scopus 로고
    • Frequency of hyperprolactinemia and its association with demographic and clinical characteristics and antipsychotic medications in psychiatric inpatients in China
    • doi: 10.1111/ppc.12050
    • Wang ZM, Xiang YT, An FR, et al. Frequency of hyperprolactinemia and its association with demographic and clinical characteristics and antipsychotic medications in psychiatric inpatients in China. Perpect Psychiatric Care 2013;doi: 10.1111/ppc.12050
    • (2013) Perpect Psychiatric Care
    • Wang, Z.M.1    Xiang, Y.T.2    An, F.R.3
  • 36
    • 84894419344 scopus 로고    scopus 로고
    • Antipsychotic-drug-inducedhyperprolactinemia: Pathophysiology, clinical features and guidance
    • Besnard I, Auclair V, Callery G, et al. Antipsychotic-drug- inducedhyperprolactinemia: Pathophysiology, clinical features and guidance. Encephale 2013;40:86-94
    • (2013) Encephale , vol.40 , pp. 86-94
    • Besnard, I.1    Auclair, V.2    Callery, G.3
  • 37
    • 84880476080 scopus 로고    scopus 로고
    • Antipsychotic-induced sexual dysfunction and its management
    • Yeon WP, Yooseok K, Yun HL. Antipsychotic-induced sexual dysfunction and its management. World J Mens Health 2012;30:153-9
    • (2012) World J Mens Health , vol.30 , pp. 153-159
    • Yeon, W.P.1    Yooseok, K.2    Yun, H.L.3
  • 38
    • 84892405949 scopus 로고    scopus 로고
    • Checking physical care of people on risperidone long term injectable depot
    • Najim H, Islam N. Checking physical care of people on risperidone long term injectable depot. Psychiatr Danub 2013;25:S171-3
    • (2013) Psychiatr Danub , vol.25
    • Najim, H.1    Islam, N.2
  • 39
    • 0034062749 scopus 로고    scopus 로고
    • Biotransformation of post-clozapine antipsychotics: Pharmacological implications
    • Caccia S. Biotransformation of post-clozapine antipsychotics: Pharmacological implications. Clin Pharmacokinet 2000;38:393-414
    • (2000) Clin Pharmacokinet , vol.38 , pp. 393-414
    • Caccia, S.1
  • 40
    • 84997860338 scopus 로고    scopus 로고
    • Continuing clozapine with granulocyte colony-stimulating factor in patients with neutropenia
    • Khan AA, Harvey J, Sengupta S. Continuing clozapine with granulocyte colony-stimulating factor in patients with neutropenia. Psychopharmacol 2013;3:266-71
    • (2013) Psychopharmacol , vol.3 , pp. 266-271
    • Khan, A.A.1    Harvey, J.2    Sengupta, S.3
  • 41
    • 84895506968 scopus 로고    scopus 로고
    • Mortality, attempted suicide, rehospitalization and prescription refill for clozapine and other antipsychotics in Sweden-A register-based study
    • Ringbäck Weitoft G, Berglund M, Lindstrom EA, et al. Mortality, attempted suicide, rehospitalization and prescription refill for clozapine and other antipsychotics in Sweden-A register-based study. Pharmacoepidemiol Drug Saf 2014;23:290-8
    • (2014) Pharmacoepidemiol Drug Saf , vol.23 , pp. 290-298
    • Ringbäck Weitoft, G.1    Berglund, M.2    Lindstrom, E.A.3
  • 42
    • 84864676108 scopus 로고    scopus 로고
    • Treatment compliance in veterans administration schizophrenia spectrum patients treated with risperidone long-Acting injectable
    • Duncan EJ, Woolson SL, Hamer RM. Treatment compliance in veterans administration schizophrenia spectrum patients treated with risperidone long-Acting injectable. Int Clin Psychopharmacol 2012;27:283-90
    • (2012) Int Clin Psychopharmacol , vol.27 , pp. 283-290
    • Duncan, E.J.1    Woolson, S.L.2    Hamer, R.M.3
  • 43
    • 84892789898 scopus 로고    scopus 로고
    • Treatment of first-episode non-Affective psychosis: A randomized comparison of aripiprazole, quetiapine and ziprasidone over 1 year
    • Crespo-Facorro B, De la Foz VO, Mata I, et al. Treatment of first-episode non-Affective psychosis: A randomized comparison of aripiprazole, quetiapine and ziprasidone over 1 year. Psychopharmacology (Berl) 2013;231:357-66
    • (2013) Psychopharmacology (Berl , vol.231 , pp. 357-366
    • Crespo-Facorro, B.1    De La Foz, V.O.2    Mata, I.3
  • 44
    • 84895077130 scopus 로고    scopus 로고
    • The advantage of using 3-week data to predict response to aripiprazole at week 6 in first-episode psychosis
    • Park JI, Cho DH, Hahn SW, et al. The advantage of using 3-week data to predict response to aripiprazole at week 6 in first-episode psychosis. Int Clin Psychopharmacol 2014;29:77-85
    • (2014) Int Clin Psychopharmacol , vol.29 , pp. 77-85
    • Park, J.I.1    Cho, D.H.2    Hahn, S.W.3
  • 45
    • 84899489706 scopus 로고    scopus 로고
    • Pharmacotherapy of treatment-resistant schizophrenia: A clinical perspective
    • Dold S, Leucht M. Pharmacotherapy of treatment-resistant schizophrenia: A clinical perspective. Evid Based Ment Health 2014;17:32-7
    • (2014) Evid Based Ment Health , vol.17 , pp. 32-37
    • Dold, S.1    Leucht, M.2
  • 46
    • 84891634194 scopus 로고    scopus 로고
    • Real-world effectiveness of antipsychotic monotherapy vs polypharmacy in schizophrenia: To switch or to combine?. A nationwide study in Hungary
    • Katona L, Czobor P, Bitter I. Real-world effectiveness of antipsychotic monotherapy vs. polypharmacy in schizophrenia: To switch or to combine?. A nationwide study in Hungary. Schizophr Res 2014;152:246-54
    • (2014) Schizophr Res , vol.152 , pp. 246-254
    • Katona, L.1    Czobor, P.2    Bitter, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.