Inherited variation in the PARP1 gene and survival from melanoma

International Journal of Cancer

Volumn 135, Issue 7, 2014, Pages 1625-1633

  Davies, John R ^a   Jewell, Rosalyn ^a   Affleck, Paul ^a   Anic, Gabriella M ^b   Randerson Moor, Juliette ^a   Ozola, Aija ^c   Egan, Kathleen M ^b   Elliott, Faye ^a   García Casado, Zaida ^d   Hansson, Johan ^e   Harland, Mark ^a   Höiom, Veronica ^e   Jian, Guan ^f   Jönsson, Göran ^g   Kumar, Rajiv ^f   Nagore, Eduardo ^d   Wendt, Judith ^h   Park, Jong Y ^b   Patel, Poulam ^i,j   Pjanova, Dace ^c   Puig, Susana ^k,l   Schadendorf, Dirk ^m   Sivaramakrishna Rachakonda, P ^f   Snowden, Helen ^a   Stratigos, Alexander J ⁿ   Bafaloukos, Dimitrios ⁿ   Ogbah, Zighereda ^k,l   Sucker, Antje ^m   Van Den Oord, Joost J ^o   Van Doorn, Remco ^p   Walker, Christy ^a   Okamoto, Ichiro ^h   Wolter, Pascal ^o   Barrett, Jennifer H ^a   Timothy Bishop, D ^a   Newton Bishop, Julia ^a   more..

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c LATVIAN BIOMEDICAL RESEARCH AND STUDY CENTRE   (Latvia)

^d INSTITUTO VALENCIANO DE ONCOLOGÍA   (Spain)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g LUND UNIVERSITY   (Sweden)

^h Universitatsklinik fur Dermatologie   (Austria)

ⁱ UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^j European Organisation for Research and Treatment of Cancer (EORTC) Melanoma Group   (United Kingdom)

^k UNIVERSITY OF BARCELONA   (Spain)

^l CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^m UNIVERSITY HOSPITAL ESSEN   (Germany)

ⁿ UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^o UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^p LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

more..

Author keywords

bioinformatics; genetic determinants of survival; melanoma; PARP1; random effects meta analysis; survival

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; SINGLE STRANDED DNA;

ARTICLE; BIOINFORMATICS; CANCER SPECIFIC SURVIVAL; CANCER SURVIVAL; COHORT ANALYSIS; CONTROLLED STUDY; DNA REPAIR; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GERMLINE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MELANOMA; OVERALL SURVIVAL; PARP1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL TIME; ULCER;

BIOINFORMATICS; GENETIC DETERMINANTS OF SURVIVAL; MELANOMA; PARP1; RANDOM EFFECTS META-ANALYSIS; SURVIVAL;

DNA, NEOPLASM; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MELANOMA; POLY(ADP-RIBOSE) POLYMERASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; QUANTITATIVE TRAIT LOCI; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 84904460022     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28796     Document Type: Article

References (35)

1. Joerger M, Burgers SA, Baas P, et al. Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study. Cancer 2012; 118: 2466-75.
2. Shiraishi K, Kohno T, Tanai C, et al. Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer. J Clin Oncol 2010; 28: 4945-52.
3. Yang JJ, Cheng C, Devidas M, et al. Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet 2011; 43: 237-41.
4. Davies JR, Randerson-Moor J, Kukalizch K, et al. Inherited variants in the MC1R gene and survival from cutaneous melanoma: a BioGenoMEL study. Pigment Cell Melanoma Res 2012; 25: 384-94.
5. Yelamos J, Farres J, Llacuna L, et al. PARP-1 and PARP-2: new players in tumor development. Am J Cancer Res 2011; 1: 328-46.
6. Shaheen M, Allen C, Nickoloff JA, et al. Synthetic lethality: exploiting the addiction of cancer to DNA repair. Blood 2011; 117: 6074-82.
7. Luo J, Solimini NL, Elledge SJ,. Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 2009; 136: 823-37.
8. Hassa PO, Hottiger MO,. A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation. Biol Chem 1999; 380: 953-9.
9. Stilmann M, Hinz M, Arslan SC, et al. A nuclear poly(ADP-ribose)- dependent signalosome confers DNA damage-induced IkappaB kinase activation. Mol Cell 2009; 36: 365-78.
10. Tentori L, Lacal PM, Muzi A, et al. Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis. Eur J Cancer 2007; 43: 2124-33.
11. Ohanna M, Giuliano S, Bonet C, et al. Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS). Genes Dev 2011; 25: 1245-61.
12. Macgregor S, Montgomery GW, Liu JZ, et al. Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nat Genet 2011; 43: 1114-18.
13. Staibano S, Pepe S, Lo Muzio L, et al. Poly(adenosine diphosphate-ribose) polymerase 1 expression in malignant melanomas from photoexposed areas of the head and neck region. Hum Pathol 2005; 36: 724-31.
14. Ernst J, Kellis M,. ChromHMM: automating chromatin-state discovery and characterization. Nat Methods 2012; 9: 215-16.
15. Sandelin A, Alkema W, Engstrom P, et al. JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res 2004; 32: D91-D94.
16. Ward LD, Kellis M,. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res 2012; 40: D930-D934.
17. Kent WJ, Sugnet CW, Furey TS, et al. The human genome browser at UCSC. Genome Res 2002; 12: 996-1006.
18. Rosenbloom KR, Sloan CA, Malladi VS, et al. ENCODE Data in the UCSC Genome Browser: year 5 update. Nucleic Acids Res 2013; 41: D56-D63.
19. Xu ZL, Taylor JA,. SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies. Nucleic Acids Res 2009; 37: W600-W605.
20. Adzhubei IA, Schmidt S, Peshkin L, et al. A method and server for predicting damaging missense mutations. Nat Methods 2010; 7: 248-9.
21. Yue P, Melamud E, Moult J,. SNPs3D: candidate gene and SNP selection for association studies. BMC Bioinformatics 2006; 7: 166.
22. Yang TP, Beazley C, Montgomery SB, et al. Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies. Bioinformatics 2010; 26: 2474-6.
23. Grundberg E, Small KS, Hedman AK, et al. Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 2012; 44: 1084-9.
24. Nica AC, Parts L, Glass D, et al. The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet 2011; 7: e1002003.
25. Sun FL, Elgin SCR,. Putting boundaries on silence. Cell 1999; 99: 459-62.
26. West AG, Gaszner M, Felsenfeld G,. Insulators: many functions, many mechanisms. Genes Dev 2002; 16: 271-88.
27. Degner JF, Pai AA, Pique-Regi R, et al. DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 2012; 482: 390-4.
28. Ba XQ, Garg NJ,. Signaling mechanism of poly (ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases. Am J Pathol 2011; 178: 946-55.
29. Hemberger M, Nozaki T, Winterhager E, et al. Parp1-deficiency induces differentiation of ES cells into trophoblast derivatives. Dev Biol 2003; 257: 371-81.
30. Harland M, Goldstein AM, Kukalizch K, et al. A comparison of CDKN2A mutation detection within the Melanoma Genetics Consortium (GenoMEL). Eur J Cancer 2008; 44: 1269-74.
31. Rodríguez MI, Peralta-Leal A, O'Valle F, et al. PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation. PLoS Genet 2013; 9: e1003531.
32. Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009; 27: 6199-206.
33. Eggermont AM, Spatz A, Lazar V, et al. Is ulceration in cutaneous melanoma just a prognostic and predictive factor or is ulcerated melanoma a distinct biologic entity? Curr Opin Oncol 2012; 24: 137-40.
34. Storr SJ, Safuan S, Mitra A, et al. Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma. Mod Pathol 2012; 25: 493-504.
35. Yang D, Khan S, Sun Y, et al. Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA 2011; 306: 1557-65.