-
1
-
-
84884906692
-
Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models
-
[Epub ahead of print]
-
Conforti P., Zuccato C., Gaudenzi G., Ieraci A., Camnasio S., Buckley N.J., Mutti C., Cotelli F., Contini A., Cattaneo E. Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models. J. Neurochem. 2013, 125. [Epub ahead of print]. 10.1111/jnc.12348.
-
(2013)
J. Neurochem.
, vol.125
-
-
Conforti, P.1
Zuccato, C.2
Gaudenzi, G.3
Ieraci, A.4
Camnasio, S.5
Buckley, N.J.6
Mutti, C.7
Cotelli, F.8
Contini, A.9
Cattaneo, E.10
-
2
-
-
59649109467
-
Decreased BDNF levels are a major contributor to the embryonic phenotype of huntingtin knockdown zebrafish
-
Diekmann H., Anichtchik O., Fleming A., Futter M., Goldsmith P., Roach A., Rubinsztein D.C. Decreased BDNF levels are a major contributor to the embryonic phenotype of huntingtin knockdown zebrafish. J. Neurosci. 2009, 29:1343-1349.
-
(2009)
J. Neurosci.
, vol.29
, pp. 1343-1349
-
-
Diekmann, H.1
Anichtchik, O.2
Fleming, A.3
Futter, M.4
Goldsmith, P.5
Roach, A.6
Rubinsztein, D.C.7
-
3
-
-
0027482789
-
Familial predisposition to recurrent mutations causing Huntington's disease: genetic risk to sibs of sporadic cases
-
Goldberg Y.P., Andrew S.E., Theilmann J., Kremer B., Squitieri F., Telenius H., Brown J.D., Hayden M.R. Familial predisposition to recurrent mutations causing Huntington's disease: genetic risk to sibs of sporadic cases. J. Med. Genet. 1993, 30:987-990.
-
(1993)
J. Med. Genet.
, vol.30
, pp. 987-990
-
-
Goldberg, Y.P.1
Andrew, S.E.2
Theilmann, J.3
Kremer, B.4
Squitieri, F.5
Telenius, H.6
Brown, J.D.7
Hayden, M.R.8
-
4
-
-
29144433643
-
Huntington disease
-
Harper B. Huntington disease. J. R. Soc. Med. 2005, 98:550.
-
(2005)
J. R. Soc. Med.
, vol.98
, pp. 550
-
-
Harper, B.1
-
5
-
-
70450189083
-
Selective neuronal requirement for Huntingtin in the developing zebrafish
-
Henshall T.L., Tucker B., Lumsden A.L., Nornes S., Lardelli M.T., Richards R.I. Selective neuronal requirement for Huntingtin in the developing zebrafish. Hum. Mol. Gen. 2009, 18:4830-4842.
-
(2009)
Hum. Mol. Gen.
, vol.18
, pp. 4830-4842
-
-
Henshall, T.L.1
Tucker, B.2
Lumsden, A.L.3
Nornes, S.4
Lardelli, M.T.5
Richards, R.I.6
-
6
-
-
0032517139
-
Characterization of the Huntington's disease (HD) gene homologue in the zebrafish Danio rerio
-
Karlovich C.A., John R.M., Ramirez L., Stainier D.Y., Myers R.M. Characterization of the Huntington's disease (HD) gene homologue in the zebrafish Danio rerio. Gene 1998, 217:117-125.
-
(1998)
Gene
, vol.217
, pp. 117-125
-
-
Karlovich, C.A.1
John, R.M.2
Ramirez, L.3
Stainier, D.Y.4
Myers, R.M.5
-
7
-
-
34247186766
-
Animal models of human disease: zebrafish swim into view
-
Lieschke G.J., Currie P.D. Animal models of human disease: zebrafish swim into view. Nat. Rev. Genet. 2007, 8:353-367.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 353-367
-
-
Lieschke, G.J.1
Currie, P.D.2
-
8
-
-
84860294838
-
An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin
-
Lo Sardo V., Zuccato C., Gaudenzi G., Vitali B., Ramos C., Tartari M., Myre M.A., Walker J.A., Pistocchi A., Conti L., Valenza M., Drung B., Schmidt B., Gusella J., Zeitlin S., Cotelli F., Cattaneo E. An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin. Nat. Neurosci. 2012, 15:713-721.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 713-721
-
-
Lo Sardo, V.1
Zuccato, C.2
Gaudenzi, G.3
Vitali, B.4
Ramos, C.5
Tartari, M.6
Myre, M.A.7
Walker, J.A.8
Pistocchi, A.9
Conti, L.10
Valenza, M.11
Drung, B.12
Schmidt, B.13
Gusella, J.14
Zeitlin, S.15
Cotelli, F.16
Cattaneo, E.17
-
9
-
-
34548406422
-
Huntingtin-deficient zebrafish exhibit defects in iron utilization and development
-
Lumsden A.L., Henshall T.L., Dayan S., Lardelli M.T., Richards R.I. Huntingtin-deficient zebrafish exhibit defects in iron utilization and development. Hum. Mol. Gen. 2007, 16:1905-1920.
-
(2007)
Hum. Mol. Gen.
, vol.16
, pp. 1905-1920
-
-
Lumsden, A.L.1
Henshall, T.L.2
Dayan, S.3
Lardelli, M.T.4
Richards, R.I.5
-
10
-
-
27144558034
-
CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo
-
Miller V.M., Nelson R.F., Gouvion C.M., Williams A., Rodriguez-Lebron E., Harper S.Q., Davidson B.L., Rebagliati M.R., Paulson H.L. CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo. J. Neurosci. 2005, 25:9152-9161.
-
(2005)
J. Neurosci.
, vol.25
, pp. 9152-9161
-
-
Miller, V.M.1
Nelson, R.F.2
Gouvion, C.M.3
Williams, A.4
Rodriguez-Lebron, E.5
Harper, S.Q.6
Davidson, B.L.7
Rebagliati, M.R.8
Paulson, H.L.9
-
11
-
-
0027435939
-
De novo expansion of a (CAG)n repeat in sporadic Huntington's disease
-
Myers R.H., MacDonald M.E., Koroshetz W.J., Duyao M.P., Ambrose C.M., Taylor S.A., Barnes G., Srinidhi J., Lin C.S., Whaley W.L., Lazzarini A.M., Schwarz M., Wolff G., Bird E.D., Vonsattel J.P.G., Gusella J.F. De novo expansion of a (CAG)n repeat in sporadic Huntington's disease. Nat. Genet. 1993, 5:168-173.
-
(1993)
Nat. Genet.
, vol.5
, pp. 168-173
-
-
Myers, R.H.1
MacDonald, M.E.2
Koroshetz, W.J.3
Duyao, M.P.4
Ambrose, C.M.5
Taylor, S.A.6
Barnes, G.7
Srinidhi, J.8
Lin, C.S.9
Whaley, W.L.10
Lazzarini, A.M.11
Schwarz, M.12
Wolff, G.13
Bird, E.D.14
Vonsattel, J.P.G.15
Gusella, J.F.16
-
12
-
-
34247869645
-
Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model
-
Schiffer N.W., Broadley S.A., Hirschberger T., Tavan P., Kretzschmar H.A., Giese A., Haass C., Hartl F.U., Schmid B. Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model. J. Biol. Chem. 2007, 282:9195-9203.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9195-9203
-
-
Schiffer, N.W.1
Broadley, S.A.2
Hirschberger, T.3
Tavan, P.4
Kretzschmar, H.A.5
Giese, A.6
Haass, C.7
Hartl, F.U.8
Schmid, B.9
-
13
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel J.P., Myers R.H., Stevens T.J., Ferrante R.J., Bird E.D., Richardson E.P. Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 1985, 44:559-577.
-
(1985)
J. Neuropathol. Exp. Neurol.
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson, E.P.6
-
14
-
-
33846225133
-
Huntington's disease
-
Walker F.O. Huntington's disease. Lancet 2007, 369:218-228.
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
15
-
-
42249106042
-
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
-
Williams A., Sarkar S., Cuddon P., Ttofi E.K., Saiki S., Siddiqi F.H., Jahreiss L., Fleming A., Pask D., Goldsmith P., O'Kane C.J., Floto R.A., Rubinsztein D.C. Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat. Chem. Biol. 2008, 4:295-305.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 295-305
-
-
Williams, A.1
Sarkar, S.2
Cuddon, P.3
Ttofi, E.K.4
Saiki, S.5
Siddiqi, F.H.6
Jahreiss, L.7
Fleming, A.8
Pask, D.9
Goldsmith, P.10
O'Kane, C.J.11
Floto, R.A.12
Rubinsztein, D.C.13
-
16
-
-
34047130812
-
Role of brain-derived neurotrophic factor in Huntington's disease
-
Zuccato C., Cattaneo E. Role of brain-derived neurotrophic factor in Huntington's disease. Prog. Neurobiol. 2007, 81:294-330.
-
(2007)
Prog. Neurobiol.
, vol.81
, pp. 294-330
-
-
Zuccato, C.1
Cattaneo, E.2
-
17
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C., Ciammola A., Rigamonti D., Leavitt B.R., Goffredo D., Conti L., MacDonald M.E., Friedlander R.M., Silani V., Hayden M.R., Timmusk T., Sipione S., Cattaneo E. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 2001, 293:493-498.
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
-
18
-
-
20444456571
-
Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery
-
Zuccato C., Liber D., Ramos C., Tarditi A., Rigamonti D., Tartari M., Valenza M., Cattaneo E. Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery. Pharmacol. Res. 2005, 52:133-139.
-
(2005)
Pharmacol. Res.
, vol.52
, pp. 133-139
-
-
Zuccato, C.1
Liber, D.2
Ramos, C.3
Tarditi, A.4
Rigamonti, D.5
Tartari, M.6
Valenza, M.7
Cattaneo, E.8
-
19
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato C., Tartari M., Crotti A., Goffredo D., Valenza M., Conti L., Cataudella T., Leavitt B.R., Hayden M.R., Timmusk T., Rigamonti D., Cattaneo E. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet. 2003, 35:76-83.
-
(2003)
Nat. Genet.
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
Rigamonti, D.11
Cattaneo, E.12
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