Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

Malaria Journal

Volumn 13, Issue 1, 2014, Pages

  Avery, Vicky M ^a   Bashyam, Sridevi ^b   Burrows, Jeremy N ^d   Duffy, Sandra ^a   Papadatos, George ^c   Puthukkuti, Shyni ^b   Sambandan, Yuvaraj ^b   Singh, Shivendra ^b   Spangenberg, Thomas ^d   Waterson, David ^d   Willis, Paul ^d  

^a GRIFFITH UNIVERSITY   (Australia)

^b SYNGENE INTERNATIONAL LTD   (India)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Italy)

^d ICC   (Switzerland)

Author keywords

Chemical diversity; Chemical library; Cheminformatics; Cluster; Drug like; High throughput screening; Hit validation; Malaria; Phenotypic; Plasmodium; Screening cascade

Indexed keywords

ANTIMALARIAL AGENT; MOLECULAR LIBRARY;

ARTICLE; COMPUTER MODEL; DEVELOPMENTAL STAGE; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; EVALUATION STUDY; GROWTH INHIBITION; IN VITRO STUDY; MEDICINAL CHEMISTRY; PHYSICAL CHEMISTRY; PLASMODIUM FALCIPARUM; PRINCIPAL COMPONENT ANALYSIS; ALGORITHM; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HUMAN; ISOLATION AND PURIFICATION; MOLECULAR LIBRARY;

ALGORITHMS; ANTIMALARIALS; DRUG EVALUATION, PRECLINICAL; HUMANS; PLASMODIUM FALCIPARUM; SMALL MOLECULE LIBRARIES;

EID: 84904391842     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-13-190     Document Type: Article

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