-
1
-
-
79951601844
-
A research agenda to underpin malaria eradication
-
Alonso, P. L., Brown, G., Arevalo-Herrera, M., Binka, F., Chitnis, C., Collins, F., Doumbo, O. K., Greenwood, B., Hall, B. F., Levine, M. M., Mendis, K., Newman, R. D., Plowe, C. V., Rodriguez, M. H., Sinden, R., Slutsker, L. and Tanner, M. (2011). A research agenda to underpin malaria eradication. PLoS Medicine 8, e1000406
-
(2011)
PLoS Medicine
, vol.8
-
-
Alonso, P.L.1
Brown, G.2
Arevalo-Herrera, M.3
Binka, F.4
Chitnis, C.5
Collins, F.6
Doumbo, O.K.7
Greenwood, B.8
Hall, B.F.9
Levine, M.M.10
Mendis, K.11
Newman, R.D.12
Plowe, C.V.13
Rodriguez, M.H.14
Sinden, R.15
Slutsker, L.16
Tanner, M.17
-
2
-
-
48249090848
-
A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes
-
Angulo-Barturen, I., Jimenez-Diaz, M. B., Mulet, T., Rullas, J., Herreros, E., Ferrer, S., Jimenez, E., Mendoza, A., Regadera, J., Rosenthal, P. J., Bathurst, I., Pompliano, D. L., Gomez de lasHeras, F. and Gargallo-Viola, D. (2008). A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes. PLoS ONE 3, e2252
-
(2008)
PLoS ONE
, vol.3
-
-
Angulo-Barturen, I.1
Jimenez-Diaz, M.B.2
Mulet, T.3
Rullas, J.4
Herreros, E.5
Ferrer, S.6
Jimenez, E.7
Mendoza, A.8
Regadera, J.9
Rosenthal, P.J.10
Bathurst, I.11
Pompliano, D.L.12
Gomez De Lasheras, F.13
Gargallo-Viola, D.14
-
3
-
-
84865832714
-
The global pipeline of new medicines for the control and elimination of malaria
-
Anthony, M. P., Burrows, J. N., Duparc, S., Moehrle, J. and Wells, T. N. C. (2012). The global pipeline of new medicines for the control and elimination of malaria. Malaria Journal 11, 316
-
(2012)
Malaria Journal
, vol.11
, pp. 316
-
-
Anthony, M.P.1
Burrows, J.N.2
Duparc, S.3
Moehrle, J.4
Wells, T.N.C.5
-
4
-
-
0344837694
-
Can primaquine therapy for vivax malaria be improved?
-
Baird, J K. and Rieckmann, K.H. (2003). Can primaquine therapy for vivax malaria be improved? Trends in Parasitology 19, 115-120
-
(2003)
Trends in Parasitology
, vol.19
, pp. 115-120
-
-
Baird, J.K.1
Rieckmann, K.H.2
-
5
-
-
77952496627
-
Revisiting the circulation time of Plasmodium falciparum gametocytes: Molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs
-
Bousema, T., Okell, L., Shekalaghe, S., Griffin, J. T., Omar, S., Sawa, P., Sutherland, C., Sauerwein, R., Ghani, A. C. and Drakeley, C. (2010). Revisiting the circulation time of Plasmodium falciparum gametocytes: Molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs. Malaria Journal 9, 136
-
(2010)
Malaria Journal
, vol.9
, pp. 136
-
-
Bousema, T.1
Okell, L.2
Shekalaghe, S.3
Griffin, J.T.4
Omar, S.5
Sawa, P.6
Sutherland, C.7
Sauerwein, R.8
Ghani, A.C.9
Drakeley, C.10
-
6
-
-
79959959354
-
The state of the art in anti-malarial drug discovery and development
-
Burrows, J. N., Chibale, K. and Wells, T. N. C. (2011b). The state of the art in anti-malarial drug discovery and development. Current Topics in Medicinal Chemistry 11, 1226-1254
-
(2011)
Current Topics in Medicinal Chemistry
, vol.11
, pp. 1226-1254
-
-
Burrows, J.N.1
Chibale, K.2
Wells, T.N.C.3
-
7
-
-
84878506144
-
Designing the next generation of medicines for malaria control and eradication
-
in press
-
Burrows, J. N., Hooft, R., Möhrle, J., Oeuvray, C. and Wells, T. N. C. (2013). Designing the next generation of medicines for malaria control and eradication. Malaria Journal in press
-
(2013)
Malaria Journal
-
-
Burrows, J.N.1
Hooft, R.2
Möhrle, J.3
Oeuvray, C.4
Wells, T.N.C.5
-
8
-
-
80052405122
-
Challenges in antimalarial drug discovery
-
Burrows, J. N., Leroy, D., Lotharius, J. and Waterson, D. (2011a). Challenges in antimalarial drug discovery. Future Medicinal Chemistry 3, 1401
-
(2011)
Future Medicinal Chemistry
, vol.3
, pp. 1401
-
-
Burrows, J.N.1
Leroy, D.2
Lotharius, J.3
Waterson, D.4
-
9
-
-
80054939377
-
Discovering new medicines to control and eradicate malaria
-
Burrows, J. N. and Waterson, D. (2011). Discovering new medicines to control and eradicate malaria. Topics in Medicinal Chemistry 7, 125-180
-
(2011)
Topics in Medicinal Chemistry
, vol.7
, pp. 125-180
-
-
Burrows, J.N.1
Waterson, D.2
-
10
-
-
79952732772
-
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicat6ed malaria
-
Charman, S. A., Arbe-Barnes, S., Bathurst, I. C., Brun, R., Campbell, M., Charman, W. N., Chiu, F. C., Chollet, J., Craft, J. C., Creek, D. J., Dong, Y., Matile, H., Maurer, M., Morizzi, J., Nguyen, T., Papastogiannidis, P., Scheurer, C., Shackleford, D. M., Sriraghavan, K., Stingelin, L., Tang, Y., Urwyler, H., Wang, X., White, K. L., Wittlin, S., Zhou, L. and Vennerstrom, J. L. (2011). Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria. Proceedings of the National Academy of Science, USA 108, 4400-4405
-
(2011)
Proceedings of the National Academy of Science, USA
, vol.108
, pp. 4400-4405
-
-
Charman, S.A.1
Arbe-Barnes, S.2
Bathurst, I.C.3
Brun, R.4
Campbell, M.5
Charman, W.N.6
Chiu, F.C.7
Chollet, J.8
Craft, J.C.9
Creek, D.J.10
Dong, Y.11
Matile, H.12
Maurer, M.13
Morizzi, J.14
Nguyen, T.15
Papastogiannidis, P.16
Scheurer, C.17
Shackleford, D.M.18
Sriraghavan, K.19
Stingelin, L.20
Tang, Y.21
Urwyler, H.22
Wang, X.23
White, K.L.24
Wittlin, S.25
Zhou, L.26
Vennerstrom, J.L.27
more..
-
11
-
-
60149084669
-
Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
-
Chico, R. M., Pittrof, R., Greenwood, B. and Chandramohan, D. (2008). Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy. Malaria Journal 7, 255
-
(2008)
Malaria Journal
, vol.7
, pp. 255
-
-
Chico, R.M.1
Pittrof, R.2
Greenwood, B.3
Chandramohan, D.4
-
12
-
-
79961223551
-
Structureguided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidatepotential
-
Coteron, J. M., Marco, M., Esquivias, J., Deng, X., White, K. L., White, J., Koltun, M., El Mazouni, F., Kokkonda, S., Katneni, K., Bhamidipati, R., Shackleford, D. M., Angulo Barturen, I., Ferrer, S. B., Jiménez- Díaz, M. B., Gamo, F. J., Goldsmith, E. J., Charman,W. N., Bathurst, I., Floyd, D., Matthews, D., Burrows, J. N., Rathod, P. K., Charman, S. A. and Phillips, M. A. (2011). Structureguided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidatepotential. Journal of Medicinal Chemistry 54, 5540-5561
-
(2011)
Journal of Medicinal Chemistry
, vol.54
, pp. 5540-5561
-
-
Coteron, J.M.1
Marco, M.2
Esquivias, J.3
Deng, X.4
White, K.L.5
White, J.6
Koltun, M.7
El Mazouni, F.8
Kokkonda, S.9
Katneni, K.10
Bhamidipati, R.11
Shackleford, D.M.12
Angulo Barturen, I.13
Ferrer, S.B.14
Jiménez-Díaz, M.B.15
Gamo, F.J.16
Goldsmith, E.J.17
Charman, W.N.18
Bathurst, I.19
Floyd, D.20
Matthews, D.21
Burrows, J.N.22
Rathod, P.K.23
Charman, S.A.24
Phillips, M.A.25
more..
-
13
-
-
34948847580
-
Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast
-
Dahl, E. L. and Rosenthal, P. J. (2007). Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. Antimicrobial Agents and Chemotherapy 51, 3485-3490
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, pp. 3485-3490
-
-
Dahl, E.L.1
Rosenthal, P.J.2
-
14
-
-
84857769077
-
The activities of current antimalarial drugs on the life cycle stages of Plasmodium: A comparative study with human and rodent parasites
-
Delves, M., Plouffe, D., Scheurer, C., Meister, S., Wittlin, S., Winzeler, E. A., Sinden, R. E. and Leroy, D. (2012). The activities of current antimalarial drugs on the life cycle stages of Plasmodium: A comparative study with human and rodent parasites. PLoS Medicine 9, e1001169
-
(2012)
PLoS Medicine
, vol.9
-
-
Delves, M.1
Plouffe, D.2
Scheurer, C.3
Meister, S.4
Wittlin, S.5
Winzeler, E.A.6
Sinden, R.E.7
Leroy, D.8
-
15
-
-
79953322662
-
Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery
-
Dembele, L., Gego, A., Zeeman, A. M., Franetich, J. F., Silvie, O., Rametti, A., Le, G. R., Dereuddre-Bosquet, N., Sauerwein, R., van Gemert, G. J., Vaillant, J. C., Thomas, A.W., Snounou, G., Kocken, C. H. and Mazier, D. (2011). Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery. PLoS ONE 6, e18162
-
(2011)
PLoS ONE
, vol.6
-
-
Dembele, L.1
Gego, A.2
Zeeman, A.M.3
Franetich, J.F.4
Silvie, O.5
Rametti, A.6
Le, G.R.7
Dereuddre-Bosquet, N.8
Sauerwein, R.9
Van Gemert, G.J.10
Vaillant, J.C.11
Thomas, A.W.12
Snounou, G.13
Kocken, C.H.14
Mazier, D.15
-
16
-
-
84865176348
-
A framework for assessing the risk of resistance for anti-malarials in development
-
Ding, X. C., Ubben, D. and Wells, T. N. (2012). A framework for assessing the risk of resistance for anti-malarials in development. Malaria Journal 11, 292
-
(2012)
Malaria Journal
, vol.11
, pp. 292
-
-
Ding, X.C.1
Ubben, D.2
Wells, T.N.3
-
17
-
-
84855645204
-
Development and optimisation of a novel 384-well anti-malarial imaging assay validated for highthroughput screening
-
Duffy, S. and Avery, V. M. (2012). Development and optimisation of a novel 384-well anti-malarial imaging assay validated for highthroughput screening. American Journal of Tropical Medicine and Hygiene 86, 84-92
-
(2012)
American Journal of Tropical Medicine and Hygiene
, vol.86
, pp. 84-92
-
-
Duffy, S.1
Avery, V.M.2
-
18
-
-
84859002052
-
Optimal dose finding for novel antimalarial combination therapy
-
Duparc, S., Lanza, C., Ubben, D., Borghini-Fuhrer, I. and Kellam, L. (2012). Optimal dose finding for novel antimalarial combination therapy. Tropical Medicine and International Health 17, 409-413
-
(2012)
Tropical Medicine and International Health
, vol.17
, pp. 409-413
-
-
Duparc, S.1
Lanza, C.2
Ubben, D.3
Borghini-Fuhrer, I.4
Kellam, L.5
-
19
-
-
77952704258
-
Thousands of chemical starting points for antimalarial lead identification
-
Gamo, F. J., Sanz, L. M., Vidal, J., de Cozar, C., Alvarez, E., Lavandera, J. L., Vanderwall, D. E., Green, D. V., Kumar, V., Hasan, S., Brown, J. R., Peishoff, C. E., Cardon, L. R. and Garcia-Bustos, J. F. (2010). Thousands of chemical starting points for antimalarial lead identification. Nature 465, 305-310
-
(2010)
Nature
, vol.465
, pp. 305-310
-
-
Gamo, F.J.1
Sanz, L.M.2
Vidal, J.3
De Cozar, C.4
Alvarez, E.5
Lavandera, J.L.6
Vanderwall, D.E.7
Green, D.V.8
Kumar, V.9
Hasan, S.10
Brown, J.R.11
Peishoff, C.E.12
Cardon, L.R.13
Garcia-Bustos, J.F.14
-
20
-
-
77952718950
-
Chemical genetics of Plasmodium falciparum
-
Guiguemde,W. A., Shelat, A. A., Bouck, D., Duffy, S., Crowther, G. J., Davis, P. H., Smithson, D. C., Connelly, M., Clark, J., Zhu, F., Jimenez-Diaz, M. B., Martinez, M. S., Wilson, E. B., Tripathi, A. K., Gut, J., Sharlow, E. R., Bathurst, I., El Mazouni, F., Fowble, J.W., Forquer, I., McGinley, P. L., Castro, S., Angulo-Barturen, I., Ferrer, S., Rosenthal, P. J., Derisi, J. L., Sullivan, D. J., Lazo, J. S., Roos, D. S., Riscoe, M. K., Phillips, M. A., Rathod, P. K., Van Voorhis, W. C., Avery, V. M. and Guy, R. K. (2010). Chemical genetics of Plasmodium falciparum. Nature 465, 311-315
-
(2010)
Nature
, vol.465
, pp. 311-315
-
-
Guiguemde, W.A.1
Shelat, A.A.2
Bouck, D.3
Duffy, S.4
Crowther, G.J.5
Davis, P.H.6
Smithson, D.C.7
Connelly, M.8
Clark, J.9
Zhu, F.10
Jimenez-Diaz, M.B.11
Martinez, M.S.12
Wilson, E.B.13
Tripathi, A.K.14
Gut, J.15
Sharlow, E.R.16
Bathurst, I.17
El Mazouni, F.18
Fowble, J.W.19
Forquer, I.20
McGinley, P.L.21
Castro, S.22
Angulo-Barturen, I.23
Ferrer, S.24
Rosenthal, P.J.25
Derisi, J.L.26
Sullivan, D.J.27
Lazo, J.S.28
Roos, D.S.29
Riscoe, M.K.30
Phillips, M.A.31
Rathod, P.K.32
Van Voorhis, W.C.33
Avery, V.M.34
Guy, R.K.35
more..
-
21
-
-
84856367163
-
Global phenotypic screening for antimalarials
-
Guiguemde, W. A., Shelat, A. A., Garcia-Bustos, J. F., Diagana, T., Gamo, F. J. and Guy, R. K. (2012). Global phenotypic screening for antimalarials. Chemistry and Biology 19, 116-129
-
(2012)
Chemistry and Biology
, vol.19
, pp. 116-129
-
-
Guiguemde, W.A.1
Shelat, A.A.2
Garcia-Bustos, J.F.3
Diagana, T.4
Gamo, F.J.5
Guy, R.K.6
-
22
-
-
64549087994
-
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice
-
Gujjar, R., Marwaha, A., El Mazouni, F., White, J., White, K. L., Creason, S., Shackleford, D. M., Baldwin, J., Charman, W. N., Buckner, F. S., Charman, S., Rathod, P. K. and Phillips, M. A. (2009). Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice. Journal of Medicinal Chemistry 52, 1864-1872
-
(2009)
Journal of Medicinal Chemistry
, vol.52
, pp. 1864-1872
-
-
Gujjar, R.1
Marwaha, A.2
El Mazouni, F.3
White, J.4
White, K.L.5
Creason, S.6
Shackleford, D.M.7
Baldwin, J.8
Charman, W.N.9
Buckner, F.S.10
Charman, S.11
Rathod, P.K.12
Phillips, M.A.13
-
23
-
-
70349313478
-
Improved murine model of malaria using Plasmodium falciparum competent strains and nonmyelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes
-
Jimenez-Diaz, M. B., Mulet, T., Viera, S., Gomez, V., Garuti, H., Ibanez, J., Alvarez-Doval, A., Shultz, L. D., Martinez, A., Gargallo-Viola, D. and Angulo-Barturen, I. (2009). Improved murine model of malaria using Plasmodium falciparum competent strains and nonmyelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes. Antimicrobial Agents and Chemotherapy 53, 4533-4536
-
(2009)
Antimicrobial Agents and Chemotherapy
, vol.53
, pp. 4533-4536
-
-
Jimenez-Diaz, M.B.1
Mulet, T.2
Viera, S.3
Gomez, V.4
Garuti, H.5
Ibanez, J.6
Alvarez-Doval, A.7
Shultz, L.D.8
Martinez, A.9
Gargallo-Viola, D.10
Angulo-Barturen, I.11
-
24
-
-
83255176722
-
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
-
Meister, S., Plouffe, D. M., Kuhen, K. L., Bonamy, G. M., Wu, T., Barnes, S.W., Bopp, s. e., Borboa, R., Bright, A. T., Che, J., Cohen, S., Dharia, N. V., Gagaring, K., Gettayacamin, M., Gordon, P., Groessl, T., Kato, N., Lee, M. C., McNamara, C.W., Fidock, D. A., Nagle, A., Nam, T. G., Richmond, W., Roland, J., Rottmann, M., Zhou, B., Froissard, P., Glynne, R. J., Mazier, D., Sattabongkot, J., Schultz, P. G., Tuntland, T., Walker, J. R., Zhou, Y., Chatterjee, A., Diagana, T. T. and Winzeler, E. A. (2011). Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science 334, 1372-1377
-
(2011)
Science
, vol.334
, pp. 1372-1377
-
-
Meister, S.1
Plouffe, D.M.2
Kuhen, K.L.3
Bonamy, G.M.4
Wu, T.5
Barnes, S.W.6
Bopp, S.E.7
Borboa, R.8
Bright, A.T.9
Che, J.10
Cohen, S.11
Dharia, N.V.12
Gagaring, K.13
Gettayacamin, M.14
Gordon, P.15
Groessl, T.16
Kato, N.17
Lee, M.C.18
McNamara, C.W.19
Fidock, D.A.20
Nagle, A.21
Nam, T.G.22
Richmond, W.23
Roland, J.24
Rottmann, M.25
Zhou, B.26
Froissard, P.27
Glynne, R.J.28
Mazier, D.29
Sattabongkot, J.30
Schultz, P.G.31
Tuntland, T.32
Walker, J.R.33
Zhou, Y.34
Chatterjee, A.35
Diagana, T.T.36
Winzeler, E.A.37
more..
-
25
-
-
84873090461
-
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials
-
Möhrle, J., Duparc, S., Siethoff, C., van Giersbergen, P. L. M., Craft, J. C., Arbe-Barnes, S., Charman, S. A., Gutierrez, M., Wittlin, S. and Vennerstrom, J. L. (2012). First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials. British Journal of Clinical Pharmacology 75, 524-537
-
(2012)
British Journal of Clinical Pharmacology
, vol.75
, pp. 524-537
-
-
Möhrle, J.1
Duparc, S.2
Siethoff, C.3
Van Giersbergen, P.L.M.4
Craft, J.C.5
Arbe-Barnes, S.6
Charman, S.A.7
Gutierrez, M.8
Wittlin, S.9
Vennerstrom, J.L.10
-
26
-
-
84861054503
-
Imidazolopiperazines: Lead optimization of the second-generation antimalarial agents
-
Nagle, A., Wu, T., Kuhen, K., Gagaring, K., Borboa, R., Francek, C., Chen, Z., Plouffe, D., Lin, X., Caldwell, C., Ek, J., Skolnik, S., Liu, F., Wang, J., Chang, J., Li, C., Liu, B., Hollenbeck, T., Tuntland, T., Isbell, J., Chuan, T., Alper, P. B., Fischli, C., Brun, R., Lakshminarayana, S. B., Rottmann, M., Diagana, T., Winzeler, E. A., Glynne, R., Tully, D. C. and Chatterjeee, A. K. (2012). Imidazolopiperazines: Lead optimization of the second-generation antimalarial agents. Journal of Medicinal Chemistry 55, 4244-4273
-
(2012)
Journal of Medicinal Chemistry
, vol.55
, pp. 4244-4273
-
-
Nagle, A.1
Wu, T.2
Kuhen, K.3
Gagaring, K.4
Borboa, R.5
Francek, C.6
Chen, Z.7
Plouffe, D.8
Lin, X.9
Caldwell, C.10
Ek, J.11
Skolnik, S.12
Liu, F.13
Wang, J.14
Chang, J.15
Li, C.16
Liu, B.17
Hollenbeck, T.18
Tuntland, T.19
Isbell, J.20
Chuan, T.21
Alper, P.B.22
Fischli, C.23
Brun, R.24
Lakshminarayana, S.B.25
Rottmann, M.26
Diagana, T.27
Winzeler, E.A.28
Glynne, R.29
Tully, D.C.30
Chatterjeee, A.K.31
more..
-
27
-
-
57749099137
-
Evidence of artemisinin-resistant malaria in western Cambodia
-
Noedl, H., Se, Y., Schaecher, K., Smith, B. L., Socheat, D. and Fukuda, M. M. (2008). Evidence of artemisinin-resistant malaria in western Cambodia. New England Journal of Medicine 359, 2619-2620
-
(2008)
New England Journal of Medicine
, vol.359
, pp. 2619-2620
-
-
Noedl, H.1
Se, Y.2
Schaecher, K.3
Smith, B.L.4
Socheat, D.5
Fukuda, M.M.6
-
28
-
-
33845903833
-
Drugs for bad bugs: Confronting the challenges of antibacterial discovery
-
Payne, D. J., Gwynn, M. N., Holmes, D. J. and Pompliano, D. L. (2007). Drugs for bad bugs: Confronting the challenges of antibacterial discovery. Nature Reviews Drug Discovery 6, 29-40
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, pp. 29-40
-
-
Payne, D.J.1
Gwynn, M.N.2
Holmes, D.J.3
Pompliano, D.L.4
-
29
-
-
84861461519
-
Emergence of artemisinin-resistant malaria on the western border of Thailand: A longitudinal study
-
Phyo, A. P., Nkhoma, S., Stepniewska, K., Ashley, E. A., Nair, S., McGready, R., Ler, M. C., Al-Saai, S., Dondorp, A. M., Lwin, K. M., Singhasivanon, P., Day, N. P., White, N. J., Anderson, T. J. and Nosten, F. (2012). Emergence of artemisinin-resistant malaria on the western border of Thailand: A longitudinal study. Lancet 379, 1960-1966
-
(2012)
Lancet
, vol.379
, pp. 1960-1966
-
-
Phyo, A.P.1
Nkhoma, S.2
Stepniewska, K.3
Ashley, E.A.4
Nair, S.5
McGready, R.6
Ler, M.C.7
Al-Saai, S.8
Dondorp, A.M.9
Lwin, K.M.10
Singhasivanon, P.11
Day, N.P.12
White, N.J.13
Anderson, T.J.14
Nosten, F.15
-
30
-
-
48249095940
-
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-Throughput screen
-
Plouffe, D., Brinker, A., McNamara, C., Henson, K., Kato, N., Kuhen, K., Nagle, A., Adrian, F., Matzen, J. T., Anderson, P., Nam, T-g., Gray, N. S., Chatterjee, A., Janes, J., Yan, S. F., Trager, R., Caldwell, J. S., Schultz, P. G., Zhou, Y. and Winzeler, E. A. (2008). In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-Throughput screen. Proceedings of the National Academy of Sciences, USA 105, 9059-9064
-
(2008)
Proceedings of the National Academy of Sciences, USA
, vol.105
, pp. 9059-9064
-
-
Plouffe, D.1
Brinker, A.2
McNamara, C.3
Henson, K.4
Kato, N.5
Kuhen, K.6
Nagle, A.7
Adrian, F.8
Matzen, J.T.9
Anderson, P.10
Nam, T.-G.11
Gray, N.S.12
Chatterjee, A.13
Janes, J.14
Yan, S.F.15
Trager, R.16
Caldwell, J.S.17
Schultz, P.G.18
Zhou, Y.19
Winzeler, E.A.20
more..
-
31
-
-
40049109886
-
Vivax malaria: Neglected and not benign
-
Suppl
-
Price, R. N., Tjitra, E., Guerra, C. A., Yeung, S., White, N. J. and Anstey, N. M. (2007). Vivax malaria: Neglected and not benign. American Journal of Tropical Medicine and Hygiene 77(6 Suppl), 79-87
-
(2007)
American Journal of Tropical Medicine and Hygiene
, vol.77
, Issue.6
, pp. 79-87
-
-
Price, R.N.1
Tjitra, E.2
Guerra, C.A.3
Yeung, S.4
White, N.J.5
Anstey, N.M.6
-
32
-
-
0014243023
-
Gametocytocidal and sporontocidal effectsof primaquine and of sulfadiazine with pyrimethamine in a chloroquine-resistant strain of Plasmodium falciparum
-
Rieckmann, K. H., McNamara, J. V., Frischer, H., Stockert, T. A., Carson, P. E. and Powell, R. D. (1968). Gametocytocidal and sporontocidal effectsof primaquine and of sulfadiazine with pyrimethamine in a chloroquine-resistant strain of Plasmodium falciparum. Bulletin of the World Health Organisation 38, 625-632
-
(1968)
Bulletin of the World Health Organisation
, vol.38
, pp. 625-632
-
-
Rieckmann, K.H.1
McNamara, J.V.2
Frischer, H.3
Stockert, T.A.4
Carson, P.E.5
Powell, R.D.6
-
34
-
-
77956280420
-
Spiroindolones, a potent compound class for the treatment of malaria
-
Rottmann, M., McNamara, C., Yeung, B. K., Lee, M. C., Zou, B., Russell, B., Seitz, P., Plouffe, D. M., Dharia, N. V., Tan, J., Cohen, S. B., Spencer, K. R., Gonzalez-Paez, G. E., Lakshminarayana, S. B., Goh, A., Suwanarusk, R., Jegla, T., Schmitt, E. K., Beck, H. P., Brun, R., Nosten, F., Renia, L., Dartois, V., Keller, T. H., Fidock, D. A., Winzeler, E. A. and Diagana, T. (2010). Spiroindolones, a potent compound class for the treatment of malaria. Science 329, 1175-1180
-
(2010)
Science
, vol.329
, pp. 1175-1180
-
-
Rottmann, M.1
McNamara, C.2
Yeung, B.K.3
Lee, M.C.4
Zou, B.5
Russell, B.6
Seitz, P.7
Plouffe, D.M.8
Dharia, N.V.9
Tan, J.10
Cohen, S.B.11
Spencer, K.R.12
Gonzalez-Paez, G.E.13
Lakshminarayana, S.B.14
Goh, A.15
Suwanarusk, R.16
Jegla, T.17
Schmitt, E.K.18
Beck, H.P.19
Brun, R.20
Nosten, F.21
Renia, L.22
Dartois, V.23
Keller, T.H.24
Fidock, D.A.25
Winzeler, E.A.26
Diagana, T.27
more..
-
35
-
-
1542358694
-
Plasmodium berghei parasite transformed with green fluorescent protein for screening blood schizontocidal agents
-
Sanchez, B. A., Mota, M. M., Sultan, A. A. and Carvalho, L.H. (2004). Plasmodium berghei parasite transformed with green fluorescent protein for screening blood schizontocidal agents. International Journal for Parasitology 34, 485-490
-
(2004)
International Journal for Parasitology
, vol.34
, pp. 485-490
-
-
Sanchez, B.A.1
Mota, M.M.2
Sultan, A.A.3
Carvalho, L.H.4
-
36
-
-
84857591058
-
Pfalciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-Action
-
Sanz, L. M., Crespo, B., De-Cozar, C., Ding, X. C., Llergo, J. L., Burrows, J. N., Garcia-Bustos, J. F. and Gamo, F. J. (2012). P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-Action. PLOS ONE 7, e30949
-
(2012)
PLOS ONE
, vol.7
-
-
Sanz, L.M.1
Crespo, B.2
De-Cozar, C.3
Ding, X.C.4
Llergo, J.L.5
Burrows, J.N.6
Garcia-Bustos, J.F.7
Gamo, F.J.8
-
37
-
-
81555221105
-
Cyclopropylcarboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screen
-
Sanz, L. M., Jimenez-Díaz, M. B., Crespo, B., De-Cozar, C., Almela, M. J., Angulo-Barturen, I., Castaneda, P., Ibanez, J., Fernandez, E. P., Ferrer, S., Herreros, E., Lozano, S., Martínez, M. S., Rueda, L., Burrows, J. N., García-Bustos, J. F. and Gamo, F. J. (2011). Cyclopropylcarboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screen. Antimicrobial Agents and Chemotherapy 55, 5740-5745
-
(2011)
Antimicrobial Agents and Chemotherapy
, vol.55
, pp. 5740-5745
-
-
Sanz, L.M.1
Jimenez-Díaz, M.B.2
Crespo, B.3
De-Cozar, C.4
Almela, M.J.5
Angulo-Barturen, I.6
Castaneda, P.7
Ibanez, J.8
Fernandez, E.P.9
Ferrer, S.10
Herreros, E.11
Lozano, S.12
Martínez, M.S.13
Rueda, L.14
Burrows, J.N.15
García-Bustos, J.F.16
Gamo, F.J.17
-
38
-
-
70350570394
-
Malaria, sexual development and transmission: Retrospect and prospect
-
Sinden, R. E. (2009). Malaria, sexual development and transmission: Retrospect and prospect. Parasitology 136, 1427-1434
-
(2009)
Parasitology
, vol.136
, pp. 1427-1434
-
-
Sinden, R.E.1
-
39
-
-
84858213521
-
The biology of sexual development of Plasmodium: The design and implementation of transmission-blocking strategies
-
Sinden, R. E., Carter, R., Drakeley, C. and Leroy, D. (2012a). The biology of sexual development of Plasmodium: The design and implementation of transmission-blocking strategies. Malaria Journal 11, 70
-
(2012)
Malaria Journal
, vol.11
, pp. 70
-
-
Sinden, R.E.1
Carter, R.2
Drakeley, C.3
Leroy, D.4
-
40
-
-
84891855597
-
Targeting the parasite in the mosquito: Rationale and practicality
-
Sinden, R. E., Delves, M. J. and Blagborough, A. M. (2012b). Targeting the parasite in the mosquito: Rationale and practicality. Malaria Journal 11(Suppl 1), O5
-
(2012)
Malaria Journal
, vol.11
, Issue.SUPPL. 1
-
-
Sinden, R.E.1
Delves, M.J.2
Blagborough, A.M.3
-
41
-
-
84879189895
-
The open access malaria box: A drug discovery catalyst for neglected diseases
-
in press
-
Spangenberg, T., Burrows, J. N., Kowalczyk, P., McDonald, S., Wells, T. N. C. and Willis, P. (2013). The open access malaria box: A drug discovery catalyst for neglected diseases. PLoS ONE, in press
-
(2013)
PLoS ONE
-
-
Spangenberg, T.1
Burrows, J.N.2
Kowalczyk, P.3
McDonald, S.4
Wells, T.N.C.5
Willis, P.6
-
42
-
-
79957703902
-
A research agenda for malaria eradication drugs
-
The malERA Consultative Group on Drugs
-
The malERA Consultative Group on Drugs. (2011). A research agenda for malaria eradication: Drugs. PLoS Medicine 8, e1000402
-
(2011)
PLoS Medicine
, vol.8
-
-
-
43
-
-
4344630762
-
Identification of an antimalarial synthetic trioxolane drug development candidate
-
Vennerstrom, J. L., Arbe-Barnes, S., Brun, R., Charman, S. A., Chiu, F. C. K., Chollet, J., Dong, Y., Dorn, A., Hunziker, D., Matile, H., McIntosh, K., Padmanilayam, M., Santo, T. J., Scheurer, C., Scorneaux, B., Tang, Y., Urwyler, H., Wittlin, S. and Charman, W. N. (2004). Identification of an antimalarial synthetic trioxolane drug development candidate. Nature 430, 900-904
-
(2004)
Nature
, vol.430
, pp. 900-904
-
-
Vennerstrom, J.L.1
Arbe-Barnes, S.2
Brun, R.3
Charman, S.A.4
Chiu, F.C.K.5
Chollet, J.6
Dong, Y.7
Dorn, A.8
Hunziker, D.9
Matile, H.10
McIntosh, K.11
Padmanilayam, M.12
Santo, T.J.13
Scheurer, C.14
Scorneaux, B.15
Tang, Y.16
Urwyler, H.17
Wittlin, S.18
Charmanti, N.19
-
44
-
-
76749083725
-
Targeting the hypnozoite reservoir of Plasmodium vivax: The hidden obstacle to malaria elimination
-
Wells, T. N. C., Burrows, J. N. and Baird, J. K. (2010). Targeting the hypnozoite reservoir of Plasmodium vivax: The hidden obstacle to malaria elimination. Trends in Parasitology 26, 145-151
-
(2010)
Trends in Parasitology
, vol.26
, pp. 145-151
-
-
Wells, T.N.C.1
Burrows, J.N.2
Baird, J.K.3
-
45
-
-
80155151284
-
Costs and cost-effectiveness of malaria control interventions-A systematic review
-
White, M. T., Conteh, L., Cibulskis, R. and Ghani, A. C. (2011). Costs and cost-effectiveness of malaria control interventions-A systematic review. Malaria Journal 10, 337
-
(2011)
Malaria Journal
, vol.10
, pp. 337
-
-
White, M.T.1
Conteh, L.2
Cibulskis, R.3
Ghani, A.C.4
-
46
-
-
31444454856
-
-
WHO, 2nd Edn. Geneva, Switzerland. ISBN 978 92 4 154792.4
-
WHO (2010). Guidelines for the Treatment of Malaria, 2nd Edn. Geneva, Switzerland. ISBN 978 92 4 154792.4
-
(2010)
Guidelines for the Treatment of Malaria
-
-
-
50
-
-
77954745330
-
Spirotetrahydrobetacarbolines (spiroindolones): A new class of potent and orally efficacious compounds for the treatment of malaria
-
Yeung, B. K., Zou, B., Rottmann, M., Lakshminarayana, S. B., Ang, S. H., Leong, S. Y., Tan, J., Wong, J., Keller-Maerki, S., Fischli, C., Goh, A., Schmitt, E. K., Krastel, P., Francotte, E., Kuhen, K., Plouffe, D., Henson, K., Wagner, T., Winzeler, E. A., Petersen, F., Brun, R., Dartois, V., Diagana, T. and Keller, T. H. (2010). Spirotetrahydrobetacarbolines (spiroindolones): A new class of potent and orally efficacious compounds for the treatment of malaria. Journal of Medicinal Chemistry 53, 5155-5164
-
(2010)
Journal of Medicinal Chemistry
, vol.53
, pp. 5155-5164
-
-
Yeung, B.K.1
Zou, B.2
Rottmann, M.3
Lakshminarayana, S.B.4
Ang, S.H.5
Leong, S.Y.6
Tan, J.7
Wong, J.8
Keller-Maerki, S.9
Fischli, C.10
Goh, A.11
Schmitt, E.K.12
Krastel, P.13
Francotte, E.14
Kuhen, K.15
Plouffe, D.16
Henson, K.17
Wagner, T.18
Winzeler, E.A.19
Petersen, F.20
Brun, R.21
Dartois, V.22
Diagana, T.23
Keller, T.H.24
more..
-
51
-
-
84867653932
-
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
-
Yuthavong, Y., Tarnchompoo, B., Vilaivan, T., Chitnumsub, P., Kamchonwongpaisan, S., Charman, S. A., McLennan, D. N., White, K. L., Vivas, L., Bongard, E., Thongphanchang, C., Taweechai, S., Vanichtanankul, J., Rattanajak, R., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W. N. and Matthews, D. (2012). Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target. Proceedings of the National Academy of Sciences, USA 109, 16823-1682
-
(2012)
Proceedings of the National Academy of Sciences, USA
, vol.109
, pp. 16823-11692
-
-
Yuthavong, Y.1
Tarnchompoo, B.2
Vilaivan, T.3
Chitnumsub, P.4
Kamchonwongpaisan, S.5
Charman, S.A.6
McLennan, D.N.7
White, K.L.8
Vivas, L.9
Bongard, E.10
Thongphanchang, C.11
Taweechai, S.12
Vanichtanankul, J.13
Rattanajak, R.14
Arwon, U.15
Fantauzzi, P.16
Yuvaniyama, J.17
Charman, W.N.18
Matthews, D.19
|