-
1
-
-
84855263748
-
Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells
-
Carcamo WC, Satoh M, Kasahara H, Terada N, Hamazaki T, Chan JY, Yao B, Tamayo S, Covini G, von Muhlen CA, Chan EK (2011) Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells. PLoS One 6(12):e29690
-
(2011)
PLoS One
, vol.6
, Issue.12
-
-
Carcamo, W.C.1
Satoh, M.2
Kasahara, H.3
Terada, N.4
Hamazaki, T.5
Chan, J.Y.6
Yao, B.7
Tamayo, S.8
Covini, G.9
Von Muhlen, C.A.10
Chan, E.K.11
-
2
-
-
84855258752
-
Cytoplasmic rods and rings autoantibodies developed during PEGylated interferon and ribavirin therapy in patients with chronic hepatitis C
-
Covini G, Carcamo WC, Bredi E, von Muhlen CA, Colombo M, Chan EKL (2012) Cytoplasmic rods and rings autoantibodies developed during PEGylated interferon and ribavirin therapy in patients with chronic hepatitis C. Antivir Ther 17(5):805-811
-
(2012)
Antivir Ther
, vol.17
, Issue.5
, pp. 805-811
-
-
Covini, G.1
Carcamo, W.C.2
Bredi, E.3
Von Muhlen, C.A.4
Colombo, M.5
Chan, E.K.L.6
-
3
-
-
80052924401
-
Glutamine analogs promote cytoophidium assembly in human and Drosophila cells
-
Chen K, Zhang J, Tastan OY, Deussen ZA, Siswick MY, Liu JL (2011) Glutamine analogs promote cytoophidium assembly in human and Drosophila cells. J Genet Genomics 38(9):391-402
-
(2011)
J Genet Genomics
, vol.38
, Issue.9
, pp. 391-402
-
-
Chen, K.1
Zhang, J.2
Tastan, O.Y.3
Deussen, Z.A.4
Siswick, M.Y.5
Liu, J.L.6
-
4
-
-
77952734418
-
Intracellular compartmentation of CTP synthase in Drosophila
-
Liu JL (2010) Intracellular compartmentation of CTP synthase in Drosophila. J Genet Genomics 37(5):281-296
-
(2010)
J Genet Genomics
, vol.37
, Issue.5
, pp. 281-296
-
-
Liu, J.L.1
-
5
-
-
79951551455
-
The enigmatic cytoophidium: Compartmentation of CTP synthase via filament formation
-
Liu JL (2011) The enigmatic cytoophidium: compartmentation of CTP synthase via filament formation. BioEssays 33(3):159-164
-
(2011)
BioEssays
, vol.33
, Issue.3
, pp. 159-164
-
-
Liu, J.L.1
-
6
-
-
80054776272
-
Autoantibodies against inosine-5?-monophosphate dehydrogenase 2 - characteristics and prevalence in patients with HCV-infection
-
Seelig HP, Appelhans H, Bauer O, Bluthner M, Hartung K, Schranz P, Schultze D, Seelig CA, Volkmann M (2011) Autoantibodies against inosine-5?-monophosphate dehydrogenase 2 - characteristics and prevalence in patients with HCV-infection. Clin Lab 57(9-10):753-765
-
(2011)
Clin Lab
, vol.57
, Issue.9-10
, pp. 753-765
-
-
Seelig, H.P.1
Appelhans, H.2
Bauer, O.3
Bluthner, M.4
Hartung, K.5
Schranz, P.6
Schultze, D.7
Seelig, C.A.8
Volkmann, M.9
-
7
-
-
33644872520
-
Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic acid by GTP
-
DOI 10.1074/jbc.M507056200
-
Ji Y, Gu J, Makhov AM, Griffith JD, Mitchell BS (2006) Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic acid by GTP. J Biol Chem 281(1):206-212 (Pubitemid 43671179)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.1
, pp. 206-212
-
-
Ji, Y.1
Gu, J.2
Makhov, A.M.3
Griffith, J.D.4
Mitchell, B.S.5
-
8
-
-
49949152179
-
Characterisation of inosine monophosphate dehydrogenase expression during retinal development: Differences between variants and isoforms
-
Gunter JH, Thomas EC, Lengefeld N, Kruger SJ, Worton L, Gardiner EM, Jones A, Barnett NL, Whitehead JP (2008) Characterisation of inosine monophosphate dehydrogenase expression during retinal development: differences between variants and isoforms. Int J Biochem Cell Biol 40(9):1716-1728
-
(2008)
Int J Biochem Cell Biol
, vol.40
, Issue.9
, pp. 1716-1728
-
-
Gunter, J.H.1
Thomas, E.C.2
Lengefeld, N.3
Kruger, S.J.4
Worton, L.5
Gardiner, E.M.6
Jones, A.7
Barnett, N.L.8
Whitehead, J.P.9
-
9
-
-
4143092510
-
Crystal structures of CTP synthetase reveal ATP, UTP, and glutamine binding sites
-
DOI 10.1016/j.str.2004.05.013, PII S0969212604002151
-
Goto M, Omi R, Nakagawa N, Miyahara I, Hirotsu K (2004) Crystal structures of CTP synthetase reveal ATP, UTP, and glutamine binding sites. Structure 12(8):1413-1423 (Pubitemid 39092086)
-
(2004)
Structure
, vol.12
, Issue.8
, pp. 1413-1423
-
-
Goto, M.1
Omi, R.2
Nakagawa, N.3
Miyahara, I.4
Hirotsu, K.5
-
10
-
-
0014217178
-
Cytidine triphosphate synthetase of Escherichia coli B. I. Purification and kinetics
-
Long CW, Pardee AB (1967) Cytidine triphosphate synthetase of Escherichia coli B. I. Purification and kinetics. J Biol Chem 242(20):4715-4721
-
(1967)
J Biol Chem
, vol.242
, Issue.20
, pp. 4715-4721
-
-
Long, C.W.1
Pardee, A.B.2
-
11
-
-
26644457413
-
Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex
-
DOI 10.1021/bi051282o
-
Endrizzi JA, Kim H, Anderson PM, Baldwin EP (2005) Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex. Biochemistry 44(41):13491-13499 (Pubitemid 41443676)
-
(2005)
Biochemistry
, vol.44
, Issue.41
, pp. 13491-13499
-
-
Endrizzi, J.A.1
Kim, H.2
Anderson, P.M.3
Baldwin, E.P.4
-
12
-
-
0036401414
-
Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis: The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis
-
DOI 10.1046/j.1432-1033.2002.03175.x
-
Willemoes M, Sigurskjold BW (2002) Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP incoupling between glutamine hydrolysis and CTP synthesis. Eur J Biochem 269(19):4772-4779 (Pubitemid 35205320)
-
(2002)
European Journal of Biochemistry
, vol.269
, Issue.19
, pp. 4772-4779
-
-
Willemoes, M.1
Sigurskjold, B.W.2
-
13
-
-
0020640494
-
Enzymes of purine metabolism in cancer
-
Weber G (1983) Enzymes of purine metabolism in cancer. Clin Biochem 16(1):57-63
-
(1983)
Clin Biochem
, vol.16
, Issue.1
, pp. 57-63
-
-
Weber, G.1
-
14
-
-
0030499593
-
Tiazofurin: Molecular and clinical action
-
Weber G, Prajda N, Abonyi M, Look KY, Tricot G (1996) Tiazofurin: molecular and clinical action. Anticancer Res 16(6A):3313-3322 (Pubitemid 27085076)
-
(1996)
Anticancer Research
, vol.16
, Issue.6 A
, pp. 3313-3322
-
-
Weber, G.1
Prajda, N.2
Abonyi, M.3
Look, K.Y.4
Tricot, G.5
-
15
-
-
0029058725
-
Inosine 5′-monophosphate dehydrogenase as a chemotherapeutic target
-
Franklin TJ, Edwards G, Hedge P (1994) Inosine 5′-monophosphate dehydrogenase as a chemotherapeutic target. Adv Exp Med Biol 370:155-160
-
(1994)
Adv Exp Med Biol
, vol.370
, pp. 155-160
-
-
Franklin, T.J.1
Edwards, G.2
Hedge, P.3
-
16
-
-
36849021519
-
Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery
-
Nair V, Shu Q (2007) Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery. Antivir Chem Chemother 18(5):245-258 (Pubitemid 350220744)
-
(2007)
Antiviral Chemistry and Chemotherapy
, vol.18
, Issue.5
, pp. 245-258
-
-
Nair, V.1
Shu, Q.2
-
17
-
-
0031638862
-
Advances in the enzymology of glutamine synthesis
-
Purich DL (1998) Advances in the enzymology of glutamine synthesis. Adv Enzymol Relat Areas Mol Biol 72:9-42
-
(1998)
Adv Enzymol Relat Areas Mol Biol
, vol.72
, pp. 9-42
-
-
Purich, D.L.1
-
18
-
-
21644477132
-
Molecular mechanisms of glutamine action
-
DOI 10.1002/jcp.20339
-
Curi R, Lagranha CJ, Doi SQ, Sellitti DF, Procopio J, Pithon-Curi TC, Corless M, Newsholme P (2005) Molecular mechanisms of glutamine action. J Cell Physiol 204(2):392-401 (Pubitemid 40934632)
-
(2005)
Journal of Cellular Physiology
, vol.204
, Issue.2
, pp. 392-401
-
-
Curi, R.1
Lagranha, C.J.2
Doi, S.Q.3
Sellitti, D.F.4
Procopio, J.5
Pithon-Curi, T.C.6
Corless, M.7
Newsholme, P.8
-
19
-
-
0021273929
-
The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation
-
Engstrom W, Zetterberg A (1984) The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation. J Cell Physiol 120(2):233-241 (Pubitemid 14096009)
-
(1984)
Journal of Cellular Physiology
, vol.120
, Issue.2
, pp. 233-241
-
-
Engstrom, W.1
Zetterberg, Z.2
-
20
-
-
0037372730
-
Glutamine and glutamate - Their central role in cell metabolism and function
-
DOI 10.1002/cbf.1003
-
Newsholme P, Procopio J, Lima MM, Pithon-Curi TC, Curi R (2003) Glutamine and glutamate-their central role in cell metabolism and function. Cell Biochem Funct 21(1):1-9 (Pubitemid 36227820)
-
(2003)
Cell Biochemistry and Function
, vol.21
, Issue.1
, pp. 1-9
-
-
Newsholme, P.1
Procopio, J.2
Ramos, L.M.M.3
Pithon-Curi, T.C.4
Curi, R.5
-
21
-
-
84879889348
-
Differential reactivity to IMPDH2 by anti-rods/rings autoantibodies and unresponsiveness to PEGylated interferon-alpha/ribavirin therapy in US and Italian HCV patients
-
Carcamo WC, Ceribelli A, Calise SJ, Krueger C, Liu C, Daves M, Villalta D, Bizzaro N, Satoh M, Chan EKL (2013) Differential reactivity to IMPDH2 by anti-rods/rings autoantibodies and unresponsiveness to PEGylated interferon-alpha/ribavirin therapy in US and Italian HCV patients. J Clin Immunol 33(2):420-426
-
(2013)
J Clin Immunol
, vol.33
, Issue.2
, pp. 420-426
-
-
Carcamo, W.C.1
Ceribelli, A.2
Calise, S.J.3
Krueger, C.4
Liu, C.5
Daves, M.6
Villalta, D.7
Bizzaro, N.8
Satoh, M.9
Chan, E.K.L.10
-
22
-
-
84866666932
-
Longitudinal study of a human drug-induced model of autoantibody to cytoplasmic rods/rings following HCV therapy with ribavirin and interferon-alpha
-
Keppeke GD, Nunes E, Ferraz ML, Silva EA, Granato C, Chan EKL, Andrade LE (2012) Longitudinal study of a human drug-induced model of autoantibody to cytoplasmic rods/rings following HCV therapy with ribavirin and interferon-alpha. PLoS One 7(9):e45392
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Keppeke, G.D.1
Nunes, E.2
Ferraz, M.L.3
Silva, E.A.4
Granato, C.5
Chan, E.K.L.6
Andrade, L.E.7
-
23
-
-
84873309603
-
Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against "rings and rods"-associated inosine-5′-monophosphate dehydrogenase 2 in viral hepatitis C
-
Probst C, Radzimski C, Blocker IM, Teegen B, Bogdanos DP, Stocker W, Komorowski L (2013) Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against "rings and rods"-associated inosine-5′-monophosphate dehydrogenase 2 in viral hepatitis C. Clin Chim Acta 418(3):91-96
-
(2013)
Clin Chim Acta
, vol.418
, Issue.3
, pp. 91-96
-
-
Probst, C.1
Radzimski, C.2
Blocker, I.M.3
Teegen, B.4
Bogdanos, D.P.5
Stocker, W.6
Komorowski, L.7
-
24
-
-
84875067863
-
Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection
-
Stinton LM, Myers RP, Coffin CS, Fritzler MJ (2013) Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection. BMC Gastroenterol 13:50
-
(2013)
BMC Gastroenterol
, vol.13
, pp. 50
-
-
Stinton, L.M.1
Myers, R.P.2
Coffin, C.S.3
Fritzler, M.J.4
-
25
-
-
84860221441
-
Cytoplasmic rings/rods as autoimmune targets of emerging human autoantibodies associated with HCV virus infection and interferon therapy
-
Conrad K, Chan EKL, Fritzler MJ, Humbel RL, von Landenberg P, Shoenfeld Y (eds) Autoantigens, autoantibodies and autoimmunity. Pabst Science Publishers, Lengerich
-
Carcamo WC, Yao B, Satoh M, Reeves WH, Liu C, Covini G, von Muhlen CA, Chan EKL (2009) Cytoplasmic rings/rods as autoimmune targets of emerging human autoantibodies associated with HCV virus infection and interferon therapy. In: Conrad K, Chan EKL, Fritzler MJ, Humbel RL, von Landenberg P, Shoenfeld Y (eds) From pathogenesis to therapy of autoimmune diseases, vol 6., Autoantigens, autoantibodies and autoimmunity. Pabst Science Publishers, Lengerich, pp 127-134
-
(2009)
From Pathogenesis to Therapy of Autoimmune Diseases
, vol.6
, pp. 127-134
-
-
Carcamo, W.C.1
Yao, B.2
Satoh, M.3
Reeves, W.H.4
Liu, C.5
Covini, G.6
Von Muhlen, C.A.7
Chan, E.K.L.8
-
26
-
-
0027198921
-
Molecular characterization of two human autoantigens: Unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex
-
Fritzler MJ, Hamel JC, Ochs RL, Chan EKL (1993) Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. J Exp Med 178(1):49-62 (Pubitemid 23173242)
-
(1993)
Journal of Experimental Medicine
, vol.178
, Issue.1
, pp. 49-62
-
-
Fritzler, M.J.1
Hamel, J.C.2
Ochs, R.L.3
Chan, E.K.L.4
-
27
-
-
34247551067
-
Autoimmune targeting of key components of RNA interference
-
Jakymiw A, Ikeda K, Fritzler MJ, Reeves WH, Satoh M, Chan EKL (2006) Autoimmune targeting of key components of RNA interference. Arthritis Res Ther 8(4):R87
-
(2006)
Arthritis Res Ther
, vol.8
, Issue.4
-
-
Jakymiw, A.1
Ikeda, K.2
Fritzler, M.J.3
Reeves, W.H.4
Satoh, M.5
Chan, E.K.L.6
-
28
-
-
34548478113
-
Small interfering RNA-mediated silencing induces target-dependent assembly of GW/P bodies
-
DOI 10.1091/mbc.E07-01-0070
-
Lian S, Fritzler MJ, Katz J, Hamazaki T, Terada N, Satoh M, Chan EKL (2007) Small interfering RNA-mediated silencing induces target-dependent assembly of GW/P bodies. Mol Biol Cell 18(9):3375-3387 (Pubitemid 47378678)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.9
, pp. 3375-3387
-
-
Lian, S.1
Fritzler, M.J.2
Katz, J.3
Hamazaki, T.4
Terada, N.5
Satoh, M.6
Chan, E.K.L.7
-
29
-
-
0035933201
-
Trypanosoma brucei CTP synthetase: A target for the treatment of African sleeping sickness
-
DOI 10.1073/pnas.111139498
-
Hofer A, Steverding D, Chabes A, Brun R, Thelander L (2001) Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness. Proc Natl Acad Sci USA 98(11):6412-6416 (Pubitemid 32488251)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.11
, pp. 6412-6416
-
-
Hofer, A.1
Steverding, D.2
Chabes, A.3
Brun, R.4
Thelander, L.5
-
30
-
-
14944380669
-
Glutamine-dependent changes in gene expression and protein activity
-
DOI 10.1002/cbf.1165
-
Curi R, Lagranha CJ, Doi SQ, Sellitti DF, Procopio J, Pithon-Curi TC (2005) Glutamine-dependent changes in gene expression and protein activity. Cell Biochem Funct 23(2):77-84 (Pubitemid 40363678)
-
(2005)
Cell Biochemistry and Function
, vol.23
, Issue.2
, pp. 77-84
-
-
Curi, R.1
Lagranha, C.J.2
Doi, S.Q.3
Sellitti, D.F.4
Procopio, J.5
Pithon-Curi, T.C.6
-
31
-
-
0026003447
-
Guanosine metabolism in adult rat cardiac myocytes: Ribose-enhanced GTP synthesis from extracellular guanosine
-
Geisbuhler TP, Rovetto MJ (1991) Guanosine metabolism in adult rat cardiac myocytes: ribose-enhanced GTP synthesis from extracellular guanosine. Pflug Arch 419(2):160-165
-
(1991)
Pflug Arch
, vol.419
, Issue.2
, pp. 160-165
-
-
Geisbuhler, T.P.1
Rovetto, M.J.2
-
32
-
-
0018823799
-
Pyrimidine nucleotide biosynthesis in animals: Genes, enzymes, and regulation of UMP biosynthesis
-
Jones ME (1980) Pyrimidine nucleotide biosynthesis in animals: genes, enzymes, and regulation of UMP biosynthesis. Annu Rev Biochem 49:253-279
-
(1980)
Annu Rev Biochem
, vol.49
, pp. 253-279
-
-
Jones, M.E.1
-
33
-
-
77955906574
-
Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogaster
-
Noree C, Sato BK, Broyer RM, Wilhelm JE (2010) Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogaster. J Cell Biol 190(4):541-551
-
(2010)
J Cell Biol
, vol.190
, Issue.4
, pp. 541-551
-
-
Noree, C.1
Sato, B.K.2
Broyer, R.M.3
Wilhelm, J.E.4
-
34
-
-
0018622539
-
Selective high metabolic lability of uridine, guanosine and cytosine triphosphates in response to glucose deprivation and refeeding of untransformed and polyoma virus-transformed hamster fibroblasts
-
Rapaport E, Christopher CW, Svihovec SK, Ullrey D, Kalckar HM (1979) Selective high metabolic lability of uridine, guanosine and cytosine triphosphates in response to glucose deprivation and refeeding of untransformed and polyoma virus-transformed hamster fibroblasts. J Cell Physiol 101(2):229-235
-
(1979)
J Cell Physiol
, vol.101
, Issue.2
, pp. 229-235
-
-
Rapaport, E.1
Christopher, C.W.2
Svihovec, S.K.3
Ullrey, D.4
Kalckar, H.M.5
-
35
-
-
77955281020
-
Glutamine addiction: A new therapeutic target in cancer
-
Wise DR, Thompson CB (2010) Glutamine addiction: a new therapeutic target in cancer. Trends Biochem Sci 35(8):427-433
-
(2010)
Trends Biochem Sci
, vol.35
, Issue.8
, pp. 427-433
-
-
Wise, D.R.1
Thompson, C.B.2
-
36
-
-
0343963067
-
Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells
-
DOI 10.1007/s003940050074
-
Boza JJ, Moennoz D, Bournot CE, Blum S, Zbinden I, Finot PA, Ballevre O (2000) Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells. Eur J Nutr 39(1):38-46 (Pubitemid 30350831)
-
(2000)
European Journal of Nutrition
, vol.39
, Issue.1
, pp. 38-46
-
-
Boza, J.J.1
Moennoz, D.2
Bournot, C.E.3
Blum, S.4
Zbinden, I.5
Finot, P.A.6
Ballevre, O.7
|