메뉴 건너뛰기




Volumn 23, Issue 2, 2005, Pages 77-84

Glutamine-dependent changes in gene expression and protein activity

Author keywords

Amino acids and tissues; Apoptosis; Cell function; Gene expression; Glutamine; Metabolism; Protein activation

Indexed keywords

ALPHA ACTIN; APOPTOSIS SIGNAL REGULATING KINASE 1; FIBRONECTIN; GLUTAMINE; GLYCOPROTEIN GP 91; MYC PROTEIN; NEUROTRANSMITTER; NITROGEN; PROTEIN C JUN; PROTEIN P22; PROTEIN P47; PROTEIN P70;

EID: 14944380669     PISSN: 02636484     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbf.1165     Document Type: Review
Times cited : (42)

References (58)
  • 2
    • 0034855732 scopus 로고    scopus 로고
    • Glutamine: The emperor or his clothes?
    • Young VR, Ajami AM. Glutamine: the emperor or his clothes? J Nutrition 2001; 131: 2449-2459.
    • (2001) J Nutrition , vol.131 , pp. 2449-2459
    • Young, V.R.1    Ajami, A.M.2
  • 4
    • 0031943019 scopus 로고    scopus 로고
    • Ammonia and amino acid metabolism in skeletal muscle: Human, rodent and canine models
    • Graham TE, MacLean DA. Ammonia and amino acid metabolism in skeletal muscle: human, rodent and canine models. Med Sci Sports Exerc 1998; 30: 34-46.
    • (1998) Med Sci Sports Exerc , vol.30 , pp. 34-46
    • Graham, T.E.1    MacLean, D.A.2
  • 5
    • 0025196959 scopus 로고
    • Metabolism and role of glutamate in mammalian brain
    • Erecinska M, Silver IA. Metabolism and role of glutamate in mammalian brain. Prog Neurobiol 1990; 32: 245-296.
    • (1990) Prog Neurobiol , vol.32 , pp. 245-296
    • Erecinska, M.1    Silver, I.A.2
  • 6
    • 0025231570 scopus 로고
    • Nitrogen metabolism in liver: Structural and functional organization and physiological relevance
    • Haussinger D. Nitrogen metabolism in liver: structural and functional organization and physiological relevance. Biochem J 1990; 267: 281-290.
    • (1990) Biochem J , vol.267 , pp. 281-290
    • Haussinger, D.1
  • 7
    • 0020019301 scopus 로고
    • Glutamine utilization by the small intestine
    • Windmueller HG. Glutamine utilization by the small intestine. Adv Enzymol 1982; 53: 201-237.
    • (1982) Adv Enzymol , vol.53 , pp. 201-237
    • Windmueller, H.G.1
  • 8
    • 0037113181 scopus 로고    scopus 로고
    • Effect of starvation on glutamine ammoniagenesis and gluconeogenesis in isolated mouse kidney tubules
    • Conjard A, Brun V, Martin M, Baverel G, Ferrier B. Effect of starvation on glutamine ammoniagenesis and gluconeogenesis in isolated mouse kidney tubules. Biochem J 2002; 368: 301-308.
    • (2002) Biochem J , vol.368 , pp. 301-308
    • Conjard, A.1    Brun, V.2    Martin, M.3    Baverel, G.4    Ferrier, B.5
  • 9
    • 0036090984 scopus 로고    scopus 로고
    • Walker 256 tumour growth causes marked changes of glutamine metabolism in rat small intestine
    • Ramos Lima MM, de Mello MA, Curi R. Walker 256 tumour growth causes marked changes of glutamine metabolism in rat small intestine. Cell Biochem Funct 2002; 20: 107-113.
    • (2002) Cell Biochem Funct , vol.20 , pp. 107-113
    • Ramos Lima, M.M.1    De Mello, M.A.2    Curi, R.3
  • 10
    • 0026685167 scopus 로고
    • Cotransport of sodium with glutamine, alanine and glucose in the isolated rabbit ileal mucosa
    • Lima AA, Soares AM, Freire Junior JE, Guerrant RL. Cotransport of sodium with glutamine, alanine and glucose in the isolated rabbit ileal mucosa. Braz J Med Biol Res 1992; 25: 637-640.
    • (1992) Braz J Med Biol Res , vol.25 , pp. 637-640
    • Lima, A.A.1    Soares, A.M.2    Freire Junior, J.E.3    Guerrant, R.L.4
  • 13
    • 0036130362 scopus 로고    scopus 로고
    • Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death
    • Mates JM, Perez-Gomez C, Nunez de Castro I, Asenjo M, Marquez J. Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death. Int J Biochem Cell Biol 2002; 34: 439-458.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 439-458
    • Mates, J.M.1    Perez-Gomez, C.2    Nunez De Castro, I.3    Asenjo, M.4    Marquez, J.5
  • 14
    • 0032602636 scopus 로고    scopus 로고
    • Metabolic fate of glutamine in lymphocytes, macrophages and neutrophils
    • Curi R, Newsholme P, Pithon-Curi TC, et al. Metabolic fate of glutamine in lymphocytes, macrophages and neutrophils. Braz J Med Biol Res 1999; 32: 15-21.
    • (1999) Braz J Med Biol Res , vol.32 , pp. 15-21
    • Curi, R.1    Newsholme, P.2    Pithon-Curi, T.C.3
  • 15
    • 0023029455 scopus 로고
    • Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages
    • Newsholme P, Curi R, Gordon S, Newsholme EA. Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. Biochem J 1986; 239: 121-125.
    • (1986) Biochem J , vol.239 , pp. 121-125
    • Newsholme, P.1    Curi, R.2    Gordon, S.3    Newsholme, E.A.4
  • 18
    • 0018975576 scopus 로고
    • The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets
    • Malaisse WJ, Sener A, Carpinelli AR, et al. The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets. Mol Cell Endocrinol. 1980; 20: 171-189.
    • (1980) Mol Cell Endocrinol. , vol.20 , pp. 171-189
    • Malaisse, W.J.1    Sener, A.2    Carpinelli, A.R.3
  • 19
    • 0019454290 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release. Biosynthetic and secretory responses of rat pancreatic islet to L-leucine and L-glutamine
    • Sener A, Somers G, Devis G, Malaisse WJ. The stimulus-secretion coupling of amino acid-induced insulin release. Biosynthetic and secretory responses of rat pancreatic islet to L-leucine and L-glutamine. Diabetologia 1981; 21: 135-142.
    • (1981) Diabetologia , vol.21 , pp. 135-142
    • Sener, A.1    Somers, G.2    Devis, G.3    Malaisse, W.J.4
  • 20
    • 0023953592 scopus 로고
    • Glutamine metabolism in isolated incubated adipocytes of the rat
    • Kowalchuk JM, Curi R, Newsholme EA. Glutamine metabolism in isolated incubated adipocytes of the rat. Biochem J 1988; 249: 705-708.
    • (1988) Biochem J , vol.249 , pp. 705-708
    • Kowalchuk, J.M.1    Curi, R.2    Newsholme, E.A.3
  • 21
    • 0022514925 scopus 로고
    • Intracellular distribution of some enzymes of the glutamine utilization pathway in rat lymphocytes
    • Curi R, Newsholme P, Newsholme EA. Intracellular distribution of some enzymes of the glutamine utilization pathway in rat lymphocytes. Biochem Biophys Res Commun 1986; 138: 318-322.
    • (1986) Biochem Biophys Res Commun , vol.138 , pp. 318-322
    • Curi, R.1    Newsholme, P.2    Newsholme, E.A.3
  • 22
    • 0343963067 scopus 로고    scopus 로고
    • Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells
    • Boza JJ, Moennoz D, Bournot CE, et al. Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells. Eur J Nutr 2000; 39: 38-46.
    • (2000) Eur J Nutr , vol.39 , pp. 38-46
    • Boza, J.J.1    Moennoz, D.2    Bournot, C.E.3
  • 24
    • 0036195042 scopus 로고    scopus 로고
    • Regulative potential of glutamine-Relation to glutathione metabolism
    • Roth E, Oehler R, Manhart N, et al. Regulative potential of glutamine-Relation to glutathione metabolism. Nutrition 2002; 18: 217-221.
    • (2002) Nutrition , vol.18 , pp. 217-221
    • Roth, E.1    Oehler, R.2    Manhart, N.3
  • 25
    • 17944401183 scopus 로고    scopus 로고
    • Glutamine attenuates post-traumatic glutathione depletion in human muscle
    • Flaring UB, Rooyackers OE, Wernerman J, Hammarqvist F. Glutamine attenuates post-traumatic glutathione depletion in human muscle. Clin Sci 2003; 104: 275-282.
    • (2003) Clin Sci , vol.104 , pp. 275-282
    • Flaring, U.B.1    Rooyackers, O.E.2    Wernerman, J.3    Hammarqvist, F.4
  • 26
    • 0025475371 scopus 로고
    • Is glutamine a conditionally essential amino acid?
    • Lacey JM, Wilmore DW. Is glutamine a conditionally essential amino acid? Nutr Rev 1990; 48: 297-309.
    • (1990) Nutr Rev , vol.48 , pp. 297-309
    • Lacey, J.M.1    Wilmore, D.W.2
  • 28
    • 0030773531 scopus 로고    scopus 로고
    • Glutamine-enhanced bacterial killing by neutrophils from post-operative patients
    • Furukawa S, Saito H, Fukatsu K. Glutamine-enhanced bacterial killing by neutrophils from post-operative patients. Nutrition 1997; 13: 853-863.
    • (1997) Nutrition , vol.13 , pp. 853-863
    • Furukawa, S.1    Saito, H.2    Fukatsu, K.3
  • 29
    • 0028010990 scopus 로고
    • Effect of long-distance running on polymorphonuclear neutrophil phagocytic function of the upper airways
    • Muns G. Effect of long-distance running on polymorphonuclear neutrophil phagocytic function of the upper airways. Int J Sports Med 1994; 15: 96-99.
    • (1994) Int J Sports Med , vol.15 , pp. 96-99
    • Muns, G.1
  • 30
    • 0029670025 scopus 로고    scopus 로고
    • Glutamine increases argininosuccinate synthase mRNA levels in rat hepatocytes. The involvement of cell swelling
    • Quillard M, Husson A, Lavoinne A. Glutamine increases argininosuccinate synthase mRNA levels in rat hepatocytes. The involvement of cell swelling. Eur J Biochem 1996; 236: 56-59.
    • (1996) Eur J Biochem , vol.236 , pp. 56-59
    • Quillard, M.1    Husson, A.2    Lavoinne, A.3
  • 31
    • 0030425118 scopus 로고    scopus 로고
    • Glutamine inhibits the lowering effect of glucose on the level of phosphoenolpyruvate carboxykinase mRNA in isolated rat hepatocytes
    • Lavoinne A, Husson A, Quillard M, Chedeville A, Fairand A. Glutamine inhibits the lowering effect of glucose on the level of phosphoenolpyruvate carboxykinase mRNA in isolated rat hepatocytes. Eur J Biochem 1996; 242: 537-543.
    • (1996) Eur J Biochem , vol.242 , pp. 537-543
    • Lavoinne, A.1    Husson, A.2    Quillard, M.3    Chedeville, A.4    Fairand, A.5
  • 32
    • 0032179727 scopus 로고    scopus 로고
    • Glutamine and regulation of gene expression in rat hepatocytes: The role of cell swelling
    • Lavoinne A, Meisse D, Quillard M, Husson A, Renouf S, Yassad A. Glutamine and regulation of gene expression in rat hepatocytes: the role of cell swelling. Biochimie 1998; 80: 807-811.
    • (1998) Biochimie , vol.80 , pp. 807-811
    • Lavoinne, A.1    Meisse, D.2    Quillard, M.3    Husson, A.4    Renouf, S.5    Yassad, A.6
  • 33
    • 0023762019 scopus 로고
    • Does PEPCK play a key role in amino acid oxidation?
    • Curi R. Does PEPCK play a key role in amino acid oxidation? Braz J Med Biol Res 1988; 21: 27-30.
    • (1988) Braz J Med Biol Res , vol.21 , pp. 27-30
    • Curi, R.1
  • 34
    • 0036365474 scopus 로고    scopus 로고
    • Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes
    • Krause U, Bertrand L, Maisin L, Rosa M, Hue L. Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes. Eur J Biochem 2002; 269: 3742-3750.
    • (2002) Eur J Biochem , vol.269 , pp. 3742-3750
    • Krause, U.1    Bertrand, L.2    Maisin, L.3    Rosa, M.4    Hue, L.5
  • 35
    • 0030574046 scopus 로고    scopus 로고
    • Hypoosmolarity and glutamine increased β-actin gene transcription in isolated hepatocytes
    • Husson A, Quillard M, Fairand A, Chedeville A, Lavoinne A. Hypoosmolarity and glutamine increased β-actin gene transcription in isolated hepatocytes. FEBS Lett 1996; 394: 353-355.
    • (1996) FEBS Lett , vol.394 , pp. 353-355
    • Husson, A.1    Quillard, M.2    Fairand, A.3    Chedeville, A.4    Lavoinne, A.5
  • 36
    • 0035937134 scopus 로고    scopus 로고
    • Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1
    • Young-Gyu K, Kim EK, Kim T, et al. Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. J Biol Chem 2001; 276: 6030-6036.
    • (2001) J Biol Chem , vol.276 , pp. 6030-6036
    • Young-Gyu, K.1    Kim, E.K.2    Kim, T.3
  • 37
    • 0032544309 scopus 로고    scopus 로고
    • Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx
    • Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 1998; 281: 1860-1863.
    • (1998) Science , vol.281 , pp. 1860-1863
    • Chang, H.Y.1    Nishitoh, H.2    Yang, X.3    Ichijo, H.4    Baltimore, D.5
  • 38
    • 0036194103 scopus 로고    scopus 로고
    • Glutamine and heat shock protein expression
    • Wischmeyer PE. Glutamine and heat shock protein expression. Nutrition 2002; 18: 225-228.
    • (2002) Nutrition , vol.18 , pp. 225-228
    • Wischmeyer, P.E.1
  • 39
    • 0029763452 scopus 로고    scopus 로고
    • Transcriptional repression of the pro interleukin 1b gene by heat shock factor-1
    • Cahill MC, Waterman WR, Xie Y. Transcriptional repression of the pro interleukin 1b gene by heat shock factor-1. J Biol Chem 1996; 271: 17724-17730.
    • (1996) J Biol Chem , vol.271 , pp. 17724-17730
    • Cahill, M.C.1    Waterman, W.R.2    Xie, Y.3
  • 40
    • 0034657795 scopus 로고    scopus 로고
    • Anti-inflammatory effect of heat shock protein induction is related to stabilization of IkBa through preventing IkB kinase activation in respiratory epithelial cells
    • Yoo CG, Lee S, Lee CT. Anti-inflammatory effect of heat shock protein induction is related to stabilization of IkBa through preventing IkB kinase activation in respiratory epithelial cells. J Immunol 2000; 164: 5416-5420.
    • (2000) J Immunol , vol.164 , pp. 5416-5420
    • Yoo, C.G.1    Lee, S.2    Lee, C.T.3
  • 42
    • 0037221363 scopus 로고    scopus 로고
    • Glutamine attenuates tumor necrosis factor-α release and enhances heat shock protein 72 in human peripheral blood mononuclear cells
    • Wischmeyer PE, Riehm J, Singleton KD, et al. Glutamine attenuates tumor necrosis factor-α release and enhances heat shock protein 72 in human peripheral blood mononuclear cells. Nutrition 2003; 19: 1-6.
    • (2003) Nutrition , vol.19 , pp. 1-6
    • Wischmeyer, P.E.1    Riehm, J.2    Singleton, K.D.3
  • 43
    • 0030175603 scopus 로고    scopus 로고
    • Role of Fas-mediated cell death in the regulation of immune responses
    • Van Parijs L, Abbas AK. Role of Fas-mediated cell death in the regulation of immune responses. Curr Opin Immunol 1996; 8: 355-361.
    • (1996) Curr Opin Immunol , vol.8 , pp. 355-361
    • Van Parijs, L.1    Abbas, A.K.2
  • 44
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
    • Van Parijs L, Abbas AK. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 1998; 280: 243-248.
    • (1998) Science , vol.280 , pp. 243-248
    • Van Parijs, L.1    Abbas, A.K.2
  • 45
    • 0036051315 scopus 로고    scopus 로고
    • Glutamine protects activated T cells from apoptosis by up-regulating glutathione and Bcl-2 levels
    • Chang WK, Yang KD, Chuang H, Jan JJ, Shaio MF. Glutamine protects activated T cells from apoptosis by up-regulating glutathione and Bcl-2 levels. Clin Immunol 2002; 104: 151-160.
    • (2002) Clin Immunol , vol.104 , pp. 151-160
    • Chang, W.K.1    Yang, K.D.2    Chuang, H.3    Jan, J.J.4    Shaio, M.F.5
  • 46
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Ann Rev Physiol 1998; 60: 619-642.
    • (1998) Ann Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 48
    • 0842303451 scopus 로고    scopus 로고
    • Beneficial effect of glutamine on exercise-induced apoptosis of rat neutrophils
    • Lagranha CJ, Senna SM, Lima TM, et al. Beneficial effect of glutamine on exercise-induced apoptosis of rat neutrophils. Med Sci Sports Exerc 2004; 36: 210-217.
    • (2004) Med Sci Sports Exerc , vol.36 , pp. 210-217
    • Lagranha, C.J.1    Senna, S.M.2    Lima, T.M.3
  • 49
    • 0033624249 scopus 로고    scopus 로고
    • Synthesis of interleukin 1beta and interleukin 6 by stimulated rat peritoneal macrophages: Modulation by glutamine
    • Yassad A, Husson A, Bion A, Lavoinne A. Synthesis of interleukin 1beta and interleukin 6 by stimulated rat peritoneal macrophages: modulation by glutamine. Cytokine 2000; 12: 1288-1291.
    • (2000) Cytokine , vol.12 , pp. 1288-1291
    • Yassad, A.1    Husson, A.2    Bion, A.3    Lavoinne, A.4
  • 51
    • 0038645859 scopus 로고    scopus 로고
    • Mammalian target of rapamycin and protein kinase a signaling mediate the cardiac transcriptional response to glutamine
    • Xia Y, Wen HY, Young ME, Guthrie PH, Taegtmeyer H, Kellems RE. Mammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamine. J Biol Chem 2003; 278: 13143-13150.
    • (2003) J Biol Chem , vol.278 , pp. 13143-13150
    • Xia, Y.1    Wen, H.Y.2    Young, M.E.3    Guthrie, P.H.4    Taegtmeyer, H.5    Kellems, R.E.6
  • 52
    • 0037069397 scopus 로고    scopus 로고
    • Preoperative glutamine administration induces heat-shock protein 70 expression and attenuates cardiopulmonary bypass-induced inflammatory response by regulating nitric oxide synthase activity
    • Hayashi Y, Sawa Y, Fukuyama N, Nakazawa H, Matsuda H. Preoperative glutamine administration induces heat-shock protein 70 expression and attenuates cardiopulmonary bypass-induced inflammatory response by regulating nitric oxide synthase activity. Circulation 2002; 106: 2601-2607.
    • (2002) Circulation , vol.106 , pp. 2601-2607
    • Hayashi, Y.1    Sawa, Y.2    Fukuyama, N.3    Nakazawa, H.4    Matsuda, H.5
  • 53
  • 54
    • 0038103004 scopus 로고    scopus 로고
    • Enteral non-essential amino acids stimulate protein synthesis and glutamine decreases ubiquitin mRNA level in human gut mucosa
    • Coeffier M, Claeyssens S, Hecketsweiler B, Lavoinne A, Ducrotte P, Dechelotte P. Enteral non-essential amino acids stimulate protein synthesis and glutamine decreases ubiquitin mRNA level in human gut mucosa. Am J Physiol 2003; 285: G266-G273.
    • (2003) Am J Physiol , vol.285
    • Coeffier, M.1    Claeyssens, S.2    Hecketsweiler, B.3    Lavoinne, A.4    Ducrotte, P.5    Dechelotte, P.6
  • 55
    • 0037692072 scopus 로고    scopus 로고
    • Argininosuccinate synthase from the urea cycle to the citrulline-NO cycle
    • Husson A, Brasse-Lagnel C, Fairand A, Renouf S, Avoinne A. Argininosuccinate synthase from the urea cycle to the citrulline-NO cycle. Eur J Biochem 2003; 270: 1887-1899.
    • (2003) Eur J Biochem , vol.270 , pp. 1887-1899
    • Husson, A.1    Brasse-Lagnel, C.2    Fairand, A.3    Renouf, S.4    Avoinne, A.5
  • 56
    • 0031006025 scopus 로고    scopus 로고
    • L-Glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases
    • Rhoads JM, Argenzio RA, Chen W, et al. L-Glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases. Am J Physiol 1997; 272: G943-G953.
    • (1997) Am J Physiol , vol.272
    • Rhoads, J.M.1    Argenzio, R.A.2    Chen, W.3
  • 57
    • 0031877706 scopus 로고    scopus 로고
    • Glutamine reduces heat shock-induced cell death in rat intestinal epithelial cells
    • Chow A, Zhang R. Glutamine reduces heat shock-induced cell death in rat intestinal epithelial cells. J Nutr 1998; 128: 1296-1301.
    • (1998) J Nutr , vol.128 , pp. 1296-1301
    • Chow, A.1    Zhang, R.2
  • 58
    • 0030748674 scopus 로고    scopus 로고
    • Glutamine and regulation of gene expression in mammalian cells. Special reference to PEPCK
    • Quillard M, Renouf S, Husson A, Meisse D, Lavoinne A. Glutamine and regulation of gene expression in mammalian cells. Special reference to PEPCK. Biochimie 1997; 79: 125-128.
    • (1997) Biochimie , vol.79 , pp. 125-128
    • Quillard, M.1    Renouf, S.2    Husson, A.3    Meisse, D.4    Lavoinne, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.