-
1
-
-
84880749257
-
C5a regulates IL-12+ DC migration to induce pathogenic Th1 and Th17 cells in sepsis
-
Ma N, Xing C, Xiao H, Wang Y, Wang K, et al. (2013) C5a regulates IL-12+ DC migration to induce pathogenic Th1 and Th17 cells in sepsis. PLoS One 8: e69779.
-
(2013)
PLoS One
, vol.8
-
-
Ma, N.1
Xing, C.2
Xiao, H.3
Wang, Y.4
Wang, K.5
-
2
-
-
78650176914
-
Postoperative sepsis in the United States
-
Vogel TR, Dombrovskiy VY, Carson JL, Graham AM, Lowry SF (2010) Postoperative sepsis in the United States. Ann Surg 252: 1065-1071.
-
(2010)
Ann Surg
, vol.252
, pp. 1065-1071
-
-
Vogel, T.R.1
Dombrovskiy, V.Y.2
Carson, J.L.3
Graham, A.M.4
Lowry, S.F.5
-
3
-
-
85027936428
-
Antisense inhibition of secretory and cytosolic phospholipase A2 reduces the mortality in rats with sepsis*
-
Liu MS, Liu CH, Wu G, Zhou Y (2012) Antisense inhibition of secretory and cytosolic phospholipase A2 reduces the mortality in rats with sepsis*. Crit Care Med 40: 2132-2140.
-
(2012)
Crit Care Med
, vol.40
, pp. 2132-2140
-
-
Liu, M.S.1
Liu, C.H.2
Wu, G.3
Zhou, Y.4
-
4
-
-
80052032207
-
Intravenous infusion of mesenchymal stem cells is associated with improved myocardial function during endotoxemia
-
Weil BR, Herrmann JL, Abarbanell AM, Manukyan MC, Poynter JA, et al. (2011) Intravenous infusion of mesenchymal stem cells is associated with improved myocardial function during endotoxemia. Shock 36: 235-241.
-
(2011)
Shock
, vol.36
, pp. 235-241
-
-
Weil, B.R.1
Herrmann, J.L.2
Abarbanell, A.M.3
Manukyan, M.C.4
Poynter, J.A.5
-
5
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
DOI 10.1038/nri1943, PII NRI1943
-
Hotchkiss RS, Nicholson DW (2006) Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 6: 813-822. (Pubitemid 44631650)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.11
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
6
-
-
0029880871
-
Differential induction of apoptosis in lymphoid tissues during sepsis: Variation in onset, frequency, and the nature of the mediators
-
Ayala A, Herdon CD, Lehman DL, Ayala CA, Chaudry IH (1996) Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators. Blood 87: 4261-4275. (Pubitemid 26152269)
-
(1996)
Blood
, vol.87
, Issue.10
, pp. 4261-4275
-
-
Ayala, A.1
Herdon, C.D.2
Lehman, D.L.3
Ayala, C.A.4
Chaudry, I.H.5
-
7
-
-
0033086953
-
Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis?
-
Ayala A, Xu YX, Chung CS, Chaudry IH (1999) Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis? Shock 11: 211-217.
-
(1999)
Shock
, vol.11
, pp. 211-217
-
-
Ayala, A.1
Xu, Y.X.2
Chung, C.S.3
Chaudry, I.H.4
-
8
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
DOI 10.1097/00003246-199907000-00002
-
Hotchkiss RS, Swanson PE, Freeman BD, Tinsley KW, Cobb JP, et al. (1999) Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 27: 1230-1251. (Pubitemid 29379358)
-
(1999)
Critical Care Medicine
, vol.27
, Issue.7
, pp. 1230-1251
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
9
-
-
0035338993
-
+ T lymphocytes in humans
-
Hotchkiss RS, Tinsley KW, Swanson PE, Schmieg RE Jr, Hui JJ, et al. (2001) Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol 166: 6952-6963. (Pubitemid 32467243)
-
(2001)
Journal of Immunology
, vol.166
, Issue.11
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Schmieg Jr., R.E.4
Hui, J.J.5
Chang, K.C.6
Osborne, D.F.7
Freeman, B.D.8
Cobb, J.P.9
Buchman, T.G.10
Karl, I.E.11
-
10
-
-
84894472702
-
Complete activation of autophagic process attenuates liver injury and improves survival in septic mice
-
Lin CW, Lo S, Perng DS, Wu DB, Lee PH, et al. (2014) Complete activation of autophagic process attenuates liver injury and improves survival in septic mice. Shock 41: 241-249.
-
(2014)
Shock
, vol.41
, pp. 241-249
-
-
Lin, C.W.1
Lo, S.2
Perng, D.S.3
Wu, D.B.4
Lee, P.H.5
-
11
-
-
79957446643
-
Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice
-
Carchman EH, Rao J, Loughran PA, Rosengart MR, Zuckerbraun BS (2011) Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice. Hepatology 53: 2053-2062.
-
(2011)
Hepatology
, vol.53
, pp. 2053-2062
-
-
Carchman, E.H.1
Rao, J.2
Loughran, P.A.3
Rosengart, M.R.4
Zuckerbraun, B.S.5
-
12
-
-
79955526958
-
Suppression of autophagy in rat liver at late stage of polymicrobial sepsis
-
Chien WS, Chen YH, Chiang PC, Hsiao HW, Chuang SM, et al. (2011) Suppression of autophagy in rat liver at late stage of polymicrobial sepsis. Shock 35: 506-511.
-
(2011)
Shock
, vol.35
, pp. 506-511
-
-
Chien, W.S.1
Chen, Y.H.2
Chiang, P.C.3
Hsiao, H.W.4
Chuang, S.M.5
-
13
-
-
84863229562
-
The decline of autophagy contributes to proximal tubular dysfunction during sepsis
-
Hsiao HW, Tsai KL, Wang LF, Chen YH, Chiang PC, et al. (2012) The decline of autophagy contributes to proximal tubular dysfunction during sepsis. Shock 37: 289-296.
-
(2012)
Shock
, vol.37
, pp. 289-296
-
-
Hsiao, H.W.1
Tsai, K.L.2
Wang, L.F.3
Chen, Y.H.4
Chiang, P.C.5
-
14
-
-
84872298070
-
Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice
-
Lo S, Yuan SS, Hsu C, Cheng YJ, Chang YF, et al. (2013) Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice. Ann Surg 257: 352-363.
-
(2013)
Ann Surg
, vol.257
, pp. 352-363
-
-
Lo, S.1
Yuan, S.S.2
Hsu, C.3
Cheng, Y.J.4
Chang, Y.F.5
-
15
-
-
79957499768
-
Complete induction of autophagy is essential for cardioprotection in sepsis
-
Hsieh CH, Pai PY, Hsueh HW, Yuan SS, Hsieh YC (2011) Complete induction of autophagy is essential for cardioprotection in sepsis. Ann Surg 253: 1190-1200.
-
(2011)
Ann Surg
, vol.253
, pp. 1190-1200
-
-
Hsieh, C.H.1
Pai, P.Y.2
Hsueh, H.W.3
Yuan, S.S.4
Hsieh, Y.C.5
-
16
-
-
64249123646
-
Autophagy is essential for mitochondrial clearance in mature T lymphocytes
-
Pua HH, Guo J, Komatsu M, He YW (2009) Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J Immunol 182: 4046-4055.
-
(2009)
J Immunol
, vol.182
, pp. 4046-4055
-
-
Pua, H.H.1
Guo, J.2
Komatsu, M.3
He, Y.W.4
-
17
-
-
33846461678
-
A critical role for the autophagy gene Atg5 in T cell survival and proliferation
-
DOI 10.1084/jem.20061303
-
Pua HH, Dzhagalov I, Chuck M, Mizushima N, He YW (2007) A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med 204: 25-31. (Pubitemid 46148752)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.1
, pp. 25-31
-
-
Pua, H.H.1
Dzhagalov, I.2
Chuck, M.3
Mizushima, N.4
He, Y.-W.5
-
18
-
-
76949091325
-
In vivo requirement for Atg5 in antigen presentation by dendritic cells
-
Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, et al. (2010) In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity 32: 227-239.
-
(2010)
Immunity
, vol.32
, pp. 227-239
-
-
Lee, H.K.1
Mattei, L.M.2
Steinberg, B.E.3
Alberts, P.4
Lee, Y.H.5
-
19
-
-
79251534395
-
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes
-
Jia W, Pua HH, Li QJ, He YW (2011) Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. J Immunol 186: 1564-1574.
-
(2011)
J Immunol
, vol.186
, pp. 1564-1574
-
-
Jia, W.1
Pua, H.H.2
Li, Q.J.3
He, Y.W.4
-
20
-
-
34548700401
-
T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis
-
DOI 10.1016/j.immuni.2007.07.022, PII S1074761307004177
-
Harris J, De Haro SA, Master SS, Keane J, Roberts EA, et al. (2007) T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. Immunity 27: 505-517. (Pubitemid 47418681)
-
(2007)
Immunity
, vol.27
, Issue.3
, pp. 505-517
-
-
Harris, J.1
De Haro, S.A.2
Master, S.S.3
Keane, J.4
Roberts, E.A.5
Delgado, M.6
Deretic, V.7
-
21
-
-
8344247016
-
Autophagy defends cells against invading group A Streptococcus
-
DOI 10.1126/science.1103966
-
Nakagawa I, Amano A, Mizushima N, Yamamoto A, Yamaguchi H, et al. (2004) Autophagy defends cells against invading group A Streptococcus. Science 306: 1037-1040. (Pubitemid 39482907)
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 1037-1040
-
-
Nakagawa, I.1
Amano, A.2
Mizushima, N.3
Yamamoto, A.4
Yamaguchi, H.5
Kamimoto, T.6
Nara, A.7
Funao, J.8
Nakata, M.9
Tsuda, K.10
Hamada, S.11
Yoshimori, T.12
-
22
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
-
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, et al. (2004) Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119: 753-766. (Pubitemid 40017683)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
Taylor, G.A.4
Colombo, M.I.5
Deretic, V.6
-
23
-
-
84893441002
-
Autophagy adaptor protein p62/SQSTM1 and autophagy-related gene Atg5 mediate autophagosome formation in response to Mycobacterium tuberculosis infection in dendritic cells
-
Seto S, Tsujimura K, Horii T, Koide Y (2013) Autophagy adaptor protein p62/SQSTM1 and autophagy-related gene Atg5 mediate autophagosome formation in response to Mycobacterium tuberculosis infection in dendritic cells. PLoS One 8: e86017.
-
(2013)
PLoS One
, vol.8
-
-
Seto, S.1
Tsujimura, K.2
Horii, T.3
Koide, Y.4
-
24
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
DOI 10.1126/science.1136880
-
Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A (2007) Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 315: 1398-1401. (Pubitemid 46399546)
-
(2007)
Science
, vol.315
, Issue.5817
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
25
-
-
61849140067
-
When apoptosis meets autophagy: Deciding cell fate after trauma and sepsis
-
Hsieh YC, Athar M, Chaudry IH (2009) When apoptosis meets autophagy: deciding cell fate after trauma and sepsis. Trends Mol Med 15: 129-138.
-
(2009)
Trends Mol Med
, vol.15
, pp. 129-138
-
-
Hsieh, Y.C.1
Athar, M.2
Chaudry, I.H.3
-
26
-
-
0032898636
-
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy
-
Tanida I, Mizushima N, Kiyooka M, Ohsumi M, Ueno T, et al. (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10: 1367-1379. (Pubitemid 29230896)
-
(1999)
Molecular Biology of the Cell
, vol.10
, Issue.5
, pp. 1367-1379
-
-
Tanida, I.1
Mizushima, N.2
Kiyooka, M.3
Ohsumi, M.4
Ueno, T.5
Ohsumi, Y.6
Kominami, E.7
-
27
-
-
0035910423
-
The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
-
Tanida I, Tanida-Miyake E, Ueno T, Kominami E (2001) The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J Biol Chem 276: 1701-1706. (Pubitemid 32109639)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.3
, pp. 1701-1706
-
-
Tanida, I.1
Tanida-Miyake, E.2
Ueno, T.3
Kominami, E.4
-
28
-
-
84883351992
-
E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I
-
Gao W, Chen Z, Wang W, Stang MT (2013) E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. PLoS One 8: e73229.
-
(2013)
PLoS One
, vol.8
-
-
Gao, W.1
Chen, Z.2
Wang, W.3
Stang, M.T.4
-
29
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
DOI 10.1016/S1074-7613(01)00227-8
-
Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, et al. (2001) A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15: 763-774. (Pubitemid 34008504)
-
(2001)
Immunity
, vol.15
, Issue.5
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Perez-Melgosa, M.7
Sweetser, M.T.8
Schlissel, M.S.9
Nguyen, S.10
Cherry, S.R.11
Tsai, J.H.12
Tucker, S.M.13
Weaver, W.M.14
Kelso, A.15
Jaenisch, R.16
Wilson, C.B.17
-
30
-
-
0020520054
-
Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model
-
Baker CC, Chaudry IH, Gaines HO, Baue AE (1983) Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model. Surgery 94: 331-335. (Pubitemid 13043132)
-
(1983)
Surgery
, vol.94
, Issue.2
, pp. 331-335
-
-
Baker, C.C.1
Chaudry, I.H.2
Gaines, H.O.3
Baue, A.E.4
-
31
-
-
33646759609
-
Cecal ligation and puncture
-
Hubbard WJ, Choudhry M, Schwacha MG, Kerby JD, Rue LW 3rd, et al. (2005) Cecal ligation and puncture. Shock 24 Suppl 1: 52-57.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
, pp. 52-57
-
-
Hubbard, W.J.1
Choudhry, M.2
Schwacha, M.G.3
Kerby, J.D.4
Rue III, L.W.5
-
32
-
-
84876419121
-
Lc3 transgene Improves Survival and Attenuates Lung Injury Through Increasing Autophagosomal Clearance in Septic Mice
-
Lo S, Yuan SS, Hsu C, Cheng YJ, Chang YF, et al. (2012) Lc3 transgene Improves Survival and Attenuates Lung Injury Through Increasing Autophagosomal Clearance in Septic Mice. Ann Surg.
-
(2012)
Ann Surg
-
-
Lo, S.1
Yuan, S.S.2
Hsu, C.3
Cheng, Y.J.4
Chang, Y.F.5
-
33
-
-
84860434525
-
Monitoring of autophagy in Chinese hamster ovary cells using flow cytometry
-
Lee JS, Lee GM (2012) Monitoring of autophagy in Chinese hamster ovary cells using flow cytometry. Methods 56: 375-382.
-
(2012)
Methods
, vol.56
, pp. 375-382
-
-
Lee, J.S.1
Lee, G.M.2
-
34
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
DOI 10.1083/jcb.200412022
-
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, et al. (2005) Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 169: 425-434. (Pubitemid 40686693)
-
(2005)
Journal of Cell Biology
, vol.169
, Issue.3
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
35
-
-
65649151403
-
Sepsis induces extensive autophagic vacuolization in hepatocytes: A clinical and laboratory-based study
-
Watanabe E, Muenzer JT, Hawkins WG, Davis CG, Dixon DJ, et al. (2009) Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study. Lab Invest 89: 549-561.
-
(2009)
Lab Invest
, vol.89
, pp. 549-561
-
-
Watanabe, E.1
Muenzer, J.T.2
Hawkins, W.G.3
Davis, C.G.4
Dixon, D.J.5
-
36
-
-
78650643194
-
Macroautophagy regulates energy metabolism during effector T cell activation
-
Hubbard VM, Valdor R, Patel B, Singh R, Cuervo AM, et al. (2010) Macroautophagy regulates energy metabolism during effector T cell activation. J Immunol 185: 7349-7357.
-
(2010)
J Immunol
, vol.185
, pp. 7349-7357
-
-
Hubbard, V.M.1
Valdor, R.2
Patel, B.3
Singh, R.4
Cuervo, A.M.5
-
37
-
-
1842581892
-
Regulation of T Lymphocyte Metabolism
-
Frauwirth KA, Thompson CB (2004) Regulation of T lymphocyte metabolism. J Immunol 172: 4661-4665. (Pubitemid 38456383)
-
(2004)
Journal of Immunology
, vol.172
, Issue.8
, pp. 4661-4665
-
-
Frauwirth, K.A.1
Thompson, C.B.2
-
38
-
-
84856567062
-
Th1 and Th17 cells regulate innate immune responses and bacterial clearance during central nervous system infection
-
Holley MM, Kielian T (2012) Th1 and Th17 cells regulate innate immune responses and bacterial clearance during central nervous system infection. J Immunol 188: 1360-1370.
-
(2012)
J Immunol
, vol.188
, pp. 1360-1370
-
-
Holley, M.M.1
Kielian, T.2
-
40
-
-
84876784453
-
MyD88 signaling in CD4 T cells promotes IFN-gamma production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection
-
Zhang Y, Jones M, McCabe A, Winslow GM, Avram D, et al. (2013) MyD88 signaling in CD4 T cells promotes IFN-gamma production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection. J Immunol 190: 4725-4735.
-
(2013)
J Immunol
, vol.190
, pp. 4725-4735
-
-
Zhang, Y.1
Jones, M.2
McCabe, A.3
Winslow, G.M.4
Avram, D.5
-
41
-
-
84871839521
-
IFN-gamma from CD4 T cells is essential for host survival and enhances CD8 T cell function during Mycobacterium tuberculosis infection
-
Green AM, Difazio R, Flynn JL (2013) IFN-gamma from CD4 T cells is essential for host survival and enhances CD8 T cell function during Mycobacterium tuberculosis infection. J Immunol 190: 270-277.
-
(2013)
J Immunol
, vol.190
, pp. 270-277
-
-
Green, A.M.1
Difazio, R.2
Flynn, J.L.3
|