Mechanistic studies of protein arginine deiminase 2: Evidence for a substrate-assisted mechanism

Biochemistry

Volumn 53, Issue 27, 2014, Pages 4426-4433

  Dreyton, Christina J ^a   Knuckley, Bryan ^a   Jones, Justin E ^a   Lewallen, Daniel M ^a   Thompson, Paul R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GENES; ISOENZYMES; MAMMALS; MECHANICS; PROTEINS; SUBSTRATES; UREA;

ARGININE DEIMINASES; GENE TRANSCRIPTIONS; GENOMIC ORGANIZATION; MECHANISTIC DIFFERENCES; MECHANISTIC STUDIES; POST-TRANSLATIONAL MODIFICATIONS; SEQUENCE SIMILARITY; SUBSTRATE SPECIFICITY;

TRANSCRIPTION;

ARGININE DEIMINASE; CALCIUM; CYSTEINE; ENZYME INHIBITOR; ESTROGEN RECEPTOR; GUANIDINE; HISTONE H3; ISOENZYME; PROTEIN ARGININE DEIMINASE; PROTEIN ARGININE DEIMINASE 1; PROTEIN ARGININE DEIMINASE 2; PROTEIN ARGININE DEIMINASE 3; PROTEIN ARGININE DEIMINASE 4; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; DEPENDENT PERSONALITY DISORDER; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENETIC TRANSCRIPTION; HUMAN; MACROPHAGE; NUCLEOPHILICITY; ORGANIZATION; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTON TRANSPORT;

BIOCATALYSIS; CALCIUM; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLASES; ISOENZYMES; KINETICS; SOLVENTS; SUBSTRATE SPECIFICITY;

EID: 84904301810     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500554b     Document Type: Article

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