Tryptophan catabolism restricts IFN-γ-expressing neutrophils and clostridium difficile immunopathology

Journal of Immunology

Volumn 193, Issue 2, 2014, Pages 807-816

  El Zaatari, Mohamad ^a   Chang, Yu Ming ^a   Zhang, Min ^a   Franz, Matthew ^a   Shreiner, Andrew ^a   McDermott, Andrew J ^b   Van Der Sluijs, Koenraad F ^c   Lutter, René ^c   Grasberger, Helmut ^a   Kamada, Nobuhiko ^a   Young, Vincent B ^b   Huffnagle, Gary B ^b   Kao, John Y ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; KYNURENINE; MESSENGER RNA; TRYPTOPHAN;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL LOAD; CECUM; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; IMMUNOPATHOLOGY; INTESTINAL BLEEDING; LAMINA PROPRIA; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, LY; APOPTOSIS; CECUM; CLOSTRIDIUM DIFFICILE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FLOW CYTOMETRY; HOST-PATHOGEN INTERACTIONS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON-GAMMA; KYNURENINE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MODELS, IMMUNOLOGICAL; NEUTROPHILS; TRYPTOPHAN;

EID: 84904270268     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302913     Document Type: Article

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