The anticoagulant activated protein C (aPC) promotes metaplasticity in the hippocampus through an EPCR-PAR1-S1P1 receptors dependent mechanism

Hippocampus

Volumn 24, Issue 8, 2014, Pages 1030-1038

  Maggio, Nicola ^a   Itsekson, Zeev ^a   Ikenberg, Benno ^a,b   Strehl, Andreas ^a,b   Vlachos, Andreas ^b   Blatt, Ilan ^a,c   Tanne, David ^a,c   Chapman, Joab ^a,c  

^a SHEBA MEDICAL CENTER   (Israel)

^b GOETHE UNIVERSITY   (Germany)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Activated protein C; Lipid signaling; LTP; Metaplasticity; PAR1; S1P1

Indexed keywords

ACTIVATED PROTEIN C; CALCIUM ION; ENDOTHELIAL PROTEIN C RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR; ACTIVATED PROTEIN C RECEPTOR; BLOOD CLOTTING FACTOR; CALCIUM; CELL SURFACE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN C; S1PR1 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN SLICE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; HIPPOCAMPUS; INTRACELLULAR SIGNALING; LONG TERM POTENTIATION; MALE; MEPLASTICITY; MOUSE; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; ELECTROSTIMULATION; INTRACELLULAR SPACE; METABOLISM; NERVE CELL; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE;

ANIMALS; BLOOD COAGULATION FACTORS; CALCIUM; ELECTRIC STIMULATION; HIPPOCAMPUS; INTRACELLULAR SPACE; LONG-TERM POTENTIATION; MALE; MICE, INBRED C57BL; NEURONS; PROTEIN C; RECEPTOR, PAR-1; RECEPTORS, CELL SURFACE; RECEPTORS, LYSOSPHINGOLIPID; RECEPTORS, N-METHYL-D-ASPARTATE; TISSUE CULTURE TECHNIQUES;

EID: 84904266705     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.22288     Document Type: Article

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