Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1α, TNFα and oncostatin M

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Rabeony, Hanitriniaina ^a   Petit Paris, Isabelle ^a,b   Garnier, Julien ^c   Barrault, Christine ^c   Pedretti, Nathalie ^c   Guilloteau, Karline ^a   Jegou, Jean François ^a   Guillet, Gérard ^b   Huguier, Vincent ^b   Lecron, Jean Claude ^a,b   Bernard, François Xavier ^a,c   Morel, Franck ^a  

^a UNIVERSITÉ DE POITIERS   (France)

^b POITIERS UNIVERSITY HOSPITAL   (France)

^c BIOalternatives ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 22; ONCOSTATIN M; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; BIOLOGICAL MARKER; CYTOKINE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATITIS; EPIDERMIS HYPERPLASIA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; KERATINOCYTE; MOUSE; NONHUMAN; PSORIASIS VULGARIS; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; EPIDERMIS; METABOLISM; MIDDLE AGED;

ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; CYTOKINES; EPIDERMIS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-17; INTERLEUKIN-1ALPHA; INTERLEUKINS; KERATINOCYTES; MICE, INBRED C57BL; MIDDLE AGED; ONCOSTATIN M; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84904265949     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101937     Document Type: Article

References (30)

1. Candi E, Schmidt R, Melino G (2005) The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 6: 328-340. (Pubitemid 40516899)
2. Nestle FO, Kaplan DH, Barker J (2009) Psoriasis. N Engl J Med 361: 496-509.
3. Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, et al. (2006) IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med 203: 2577-2587. (Pubitemid 44833335)
4. Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, et al. (2007) Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 445: 648-651. (Pubitemid 46232884)
5. Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, et al. (2007) Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 8: 950-957. (Pubitemid 47300009)
6. Gottlieb AB, Chamian F, Masud S, Cardinale I, Abello MV, et al. (2005) TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques. J Immunol 175: 2721-2729. (Pubitemid 41113889)
7. Albanesi C, Cavani A, Girolomoni G (1999) IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J Immunol 162: 494-502. (Pubitemid 29018959)
8. Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD (1998) Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J Invest Dermatol 111: 645-649. (Pubitemid 28452327)
9. Liang SC, Tan X-Y, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, et al. (2006) Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 203: 2271-2279. (Pubitemid 44498362)
10. Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, et al. (2010) Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1{alpha}, and TNF-{alpha} Recapitulates Some Features of Psoriasis. J Immunol 184: 5256-5270.
11. Bernard FX, Morel F, Camus M, Pedretti N, Barrault C, et al. (2012) Keratinocytes under Fire of Proinflammatory Cytokines: Bona Fide Innate Immune Cells Involved in the Physiopathology of Chronic Atopic Dermatitis and Psoriasis. J Allergy (Cairo) 2012: 718725.
12. Segre JA (2006) Epidermal barrier formation and recovery in skin disorders. J Clin Invest 116: 1150-1158.
13. Nickoloff BJ, Naidu Y (1994) Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 30: 535-546. (Pubitemid 24121751)
14. Wood LC, Jackson SM, Elias PM, Grunfeld C, Feingold KR (1992) Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest 90: 482-487.
15. Wolk K, Witte E, Wallace E, Döcke W, Kunz S, et al. (2006) IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. European Journal of Immunology 36: 1309-1323.
16. Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, et al. (2005) IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol 174: 3695-3702. (Pubitemid 40354080)
17. Boniface K, Diveu C, Morel F, Pedretti N, Froger J, et al. (2007) Oncostatin M Secreted by Skin Infiltrating T Lymphocytes Is a Potent Keratinocyte Activator Involved in Skin Inflammation. J Immunol 178: 4615-4622. (Pubitemid 46492414)
18. Gazel A, Rosdy M, Bertino B, Tornier C, Sahuc F, et al. (2006) A Characteristic Subset of Psoriasis-Associated Genes Is Induced by Oncostatin-M in Reconstituted Epidermis. J Invest Dermatol 126: 2647-2657. (Pubitemid 44764049)
19. Kim BE, Howell MD, Guttman E, Gilleaudeau PM, Cardinale IR, et al. (2011) TNF-[alpha] Downregulates Filaggrin and Loricrin through c-Jun N-terminal Kinase: Role for TNF-[alpha] Antagonists to Improve Skin Barrier. J Invest Dermatol 131: 1272-1279.
20. Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suárez-Fariñas M, et al. (2008) Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. British Journal of Dermatology 159: 1092-1102.
21. Groves RW, Mizutani H, Kieffer JD, Kupper TS (1995) Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis. Proc Natl Acad Sci U S A 92: 11874-11878. (Pubitemid 26014212)
22. Mee JB, Johnson CM, Morar N, Burslem F, Groves RW (2007) The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasis. Am J Pathol 171: 32-42. (Pubitemid 47339224)
23. Guenou H, Nissan X, Larcher F, Feteira J, Lemaitre G, et al. (2009) Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study. Lancet 374: 1745-1753.
24. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
25. Sa SM, Valdez PA, Wu J, Jung K, Zhong F, et al. (2007) The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol 178: 2229-2240. (Pubitemid 46233421)
26. Sano S, Chan KS, Carbajal S, Clifford J, Peavey M, et al. (2005) Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nature Medecine 11: 43-49. (Pubitemid 40215836)
27. Lopez RG, Garcia-Silva S, Moore SJ, Bereshchenko O, Martinez-Cruz AB, et al. (2009) C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat Cell Biol 11: 1181-1190.
28. Gaffen SL (2011) Recent advances in the IL-17 cytokine family. Current Opinion in Immunology 23: 613-619.
29. Swindell WR, Johnston A, Carbajal S, Han G, Wohn C, et al. (2011) Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis. PLoS ONE 6: e18266.
30. Kupetsky EA, Mathers AR, Ferris LK (2013) Anti-cytokine therapy in the treatment of psoriasis. Cytokine 61: 704-712.