Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells

Oncotarget

Volumn 5, Issue 6, 2014, Pages 1683-1698

  Pollock, Claire B ^a,b   McDonough, Sara ^a   Wang, Victor S ^a   Lee, Hyojung ^a   Ringer, Lymor ^a,b   Li, Xin ^a   Prandi, Cristina ^c   Lee, Richard J ^d   Feldman, Adam S ^d   Koltai, Hinanit ^e   Kapulnik, Yoram ^e   Rodriguez, Olga C ^a,b   Schlegel, Richard ^a,b   Albanese, Christopher ^a,b   Yarden, Ronit I ^a,b  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c UNIVERSITY OF TURIN   (Italy)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e VOLCANI CENTER   (Israel)

Author keywords

Apoptosis; Cell cycle arrest; P38 MAPK; Plant hormone; Stress response

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHYTOHORMONE; STRESS ACTIVATED PROTEIN KINASE; STRIGOLAB; STRIGOLACTONE DERIVATIVE; UNCLASSIFIED DRUG; FUSED HETEROCYCLIC RINGS; GR24 STRIGOLACTONE; LACTONE; MESSENGER RNA; STRIGOL; TUMOR MARKER;

APOPTOSIS; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE ARREST; CELLULAR STRESS RESPONSE; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LUNG CANCER CELL LINE; MELANOMA CELL LINE; NUCLEOTIDE SEQUENCE; OSTEOSARCOMA CELL LINE; PROSTATE CANCER CELL LINE; PROTEIN CLEAVAGE; CANCER STEM CELL; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; COMPARATIVE STUDY; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; MALE; METABOLISM; NEOPLASMS; PATHOLOGY; PROSTATE; PROSTATIC NEOPLASMS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

APOPTOSIS; BIOMARKERS, TUMOR; BLOTTING, WESTERN; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; GENE EXPRESSION PROFILING; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LACTONES; MALE; NEOPLASMS; NEOPLASTIC STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTATE; PROSTATIC NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84904264283     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1849     Document Type: Article

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