Osmotic stress decreases aquaporin-4 expression in the human retinal pigment epithelial cell line, ARPE-19

International Journal of Molecular Medicine

Volumn 34, Issue 2, 2014, Pages 533-538

  Willermain, François ^a,b   Janssens, Sarah ^a,b   Arsenijevic, Tatjana ^b   Piens, Isabelle ^b   Bolaky, Nargis ^b   Caspers, Laure ^a   Perret, Jason ^b   Delporte, Christine ^b  

^a SAINT PIERRE UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Aquaporin 4; Cell; Osmotic stress; Protein degradation; Retinal pigment epithelial cells

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AQUAPORIN 4; SYNAPTOPHYSIN; UO 126; PROTEASOME;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN RETINAL PIGMENT EPITHELIAL CELL LINE; HYPEROSMOTIC STRESS; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; PIGMENT CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RETINA CELL; WESTERN BLOTTING; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; MACULAR EDEMA; METABOLISM; OSMOTIC PRESSURE; PATHOLOGY; PIGMENT EPITHELIUM; RETINA; UBIQUITINATION;

AQUAPORIN 4; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; MACULAR EDEMA; OSMOTIC PRESSURE; PROTEASOME ENDOPEPTIDASE COMPLEX; RETINA; RETINAL PIGMENT EPITHELIUM; UBIQUITINATION;

EID: 84904263926     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1791     Document Type: Article

References (49)

1. Bringmann A, Reichenbach A and Wiedemann P: Pathomechanisms of cystoid macular edema. Ophthalmic Res 36: 241-249, 2004. (Pubitemid 39664117)
2. Bringmann A, Uckermann O, Pannicke T, Iandiev I, Reichenbach A and Wiedemann P: Neuronal versus glial cell swelling in the ischaemic retina. Acta Ophthalmol Scand 83: 528-538, 2005. (Pubitemid 41488624)
3. Strauss O: The retinal pigment epithelium in visual function. Physiol Rev 85: 45-881, 2005.
4. Agre P: Aquaporin water channels (Nobel Lecture). Angew Chem Int Ed Engl 43: 4278-4290, 2004.
5. Verkman AS: Role of water channels in eye function. Exp Eye Res 76: 137-143, 2003.
6. Hollborn M, Rehak M, Iandiev I Pannicke T, Ulbricht E, Reichenbach A, Wiedemann P, Bringmann A and Kohen L: Transcriptional regulation of aquaporins in the ischemic rat retina: upregulation of aquaporin 9. Curr Eye Res 37: 514-531, 2012.
7. Stamer WD, Bok D, Hu J, Jaffe GJ and McKay BS: Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement. Invest Ophthalmol Vis Sci 44: 2803-2808, 2003. (Pubitemid 36618447)
8. Badaut J, Ashwal S and Obenaus A: Aquaporins in cerebrovascular disease: a target for treatment of brain edema? Cerebrovasc Dis 31: 521-531, 2011.
9. Papadopoulos MC and Verkman AS: Aquaporin-4 and brain edema. Pediatr Nephrol 22: 778-784, 2007. (Pubitemid 46629610)
10. Da T and Verkman AS: Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia. Invest Ophthalmol Vis Sci 45: 4477-4483, 2004. (Pubitemid 39564674)
11. Nagelhus EA, Veruki ML, Torp R, Haug FM, Laake JH, Nielsen S, Agre P and Ottersen OP: Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Muller cells and fibrous astrocytes. J Neurosci 18: 2506-2519, 1998.
12. Marmor MF and Tan F: Central serous chorioretinopathy: bilateral multifocal electroretinographic abnormalities. Arch Ophthalmol 117: 184-188, 1999. (Pubitemid 29091812)
13. Soliman W, Sander B and Jorgensen TM: Enhanced optical coherence patterns of diabetic macular oedema and their correlation with pathophysiology. Acta Ophthalmol 85: 613-617, 2005.
14. Umenishi F and Schrier RW: Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene. J Biol Chem 278: 15765-15770, 2003. (Pubitemid 36799689)
15. Umenishi F, Narikiyo T and Schrier RW: Hypertonic induction of aquaporin-1 water channel independent of transcellular osmotic gradient. Biochem Biophys Res Commun 325: 595-599, 2004. (Pubitemid 39458036)
16. Umenishi F, Narikiyo T and Schrier RW: Effect on stability, degradation, expression, and targeting of aquaporin-2 water channel by hyperosmolality in renal epithelial cells. Biochem Biophys Res Commun 338: 1593-1599, 2005. (Pubitemid 41608432)
17. Hasler U, Nunes P, Bouley R, Lu HAJ, Matsuzaki T and Brown D: Acute hypertonicity alters aquaporin-2 trafficking and induces a MAPK-dependent accumulation at the plasma membrane of renal epithelial cells. J Biol Chem 283: 26643-26661, 2008.
18. Hasler U: Controlled aquaporin-2 expression in the hypertonic environment. Am J Physiol 296: C641-C653, 2009.
19. Matsuzaki T, Suzukin T and Takata K: Hypertonicity-induced expression of aquaporin 3 in MDCK cells. Am J Physiol 281: C55-C63, 2001.
20. Sugiyama Y, Ota Y, Hara M and Inoue S: Osmotic stress up-regulation of aquaporin-3 expression in cultured human keratinocytes. Biochim Biophys Acta 1522: 82-88, 2001. (Pubitemid 34028208)
21. Arima H, Yamamoto N, Sobue K, Umenishi F, Tada T, Katsuya H and Asai K: Hyperosmolar mannitol simulates expression of aquaporins 4 and 9 through a p38 mitogen-activated protein kinase-dependent pathway in rat astrocytes. J Biol Chem 278: 44525-44534, 2003. (Pubitemid 37377205)
22. Hansen AK and Galtung HK: Aquaporin expression and cell volume regulation in the SV40 immortalized rat submandibular acinar cell line. Pflugers Arch 453: 787-796, 2007.
23. Herrlich A, Leitch V and King LS: Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction. Proc Natl Acad Sci USA 101: 15799-15804, 2004. (Pubitemid 39473568)
24. Hoffert JD, Leitch V, Agre P and King LS: Hypertonic induction of aquaporin-5 expression through an ERK-dependent pathway. J Biol Chem 275: 9070-9077, 2000. (Pubitemid 30180268)
25. Hwang SM, Lee RH, Song JM, Yoon S, Kim YS, Lee SJ, Kang SK and Jung JS: Expression of aquaporin-5 and its regulation in skeletal muscle cells. Exp Mol Med 34: 69-74, 2002. (Pubitemid 34408208)
26. Pedersen PS, Braunstein TH, Jorgensen A, Larsen PL, Holstein-Rathlou NH and Frederiksen O: Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress. Pflugers Arch 453: 777-785, 2007. (Pubitemid 46294927)
27. Zhou B, Ann DK, Li X, Kim KJ, Lin H, Minoo P, Crandall ED and Borok Z: Hypertonic induction of aquaporin-5: novel role of hypoxia-inducible factor-1alpha. Am J Physiol 292: C1280-C1290, 2007. (Pubitemid 46631724)
28. Ke C, Poon WS, Ng HK, Pang JCS and Chan Y: Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats. Neurosci Lett 301: 21-24, 2001. (Pubitemid 32182385)
29. Kasono K, Saito T, Saito T, Tamemoto H, Yanagidate C, Uchida S, Kawakami M, Sasaki S and Ishikawa SE: Hypertonicity regulates the aquaporin-2 promoter independently of arginine vasopressin. Nephrol Dial Transplant 20: 509-515, 2005. (Pubitemid 40378418)
30. Gan SW, Ran JH, Chen H, Ren ZQ, Sun SQ, Zhu SJ, Lu WT, Xu J, Zhang B, Huang J, Wang KJ and Chen Z: Lysosomal degradation of retinal glial AQP4 following its internalization induced by acute ocular hypertension. Neurosci Lett 516: 135-140, 2012.
31. Hasler U, Mordasini D, Bens M, Bianchi M, Cluzeaud F, Rousselot M, Vandewalle A, Feraille E and Martin PY: Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells. J Biol Chem 277: 10379-10386, 2002. (Pubitemid 34968157)
32. El Sherbeny A, Naggar H, Miyauchi S, Ola MS, Maddox DM, Martin PM, Ganapathy V and Smith SB: Osmoregulation of taurine transporter function and expression in retinal pigment epithelial, ganglion, and Muller cells. Invest Ophthalmol Vis Sci 45: 694-701, 2004. (Pubitemid 38140532)
33. Lin LR, Carper D, Yokoyama T and Reddy VN: The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium. Invest Ophthalmol Vis Sci 34: 2352-2359, 1993. (Pubitemid 23191266)
34. Storm R, Klussmann E, Geelhaar A, Rosenthal W and Maric K: Osmolality and solute composition are strong regulators of AQP2 expression in renal principal cells. Am J Physiol 284: F189-F198, 2003. (Pubitemid 35471299)
35. de Nadal E, Alepuz PM and Posas F: Dealing with osmostress through MAP kinase activation, EMBO Rep 3: 735-740, 2002. (Pubitemid 34966011)
36. Lehmann GL, Larocca MC, Soria LR and Marinelli RA: Aquaporins: their role in cholestatic liver disease. World J Gastroenterol 14: 7059-7067, 2008.
37. Madrid R, Le Maout S, Barrault MB, Janvier K, Benichou S and Merot J: Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes. EMBO J 20: 7008-7021, 2001. (Pubitemid 34062293)
38. Sidhaye V, Hoffert JD and King LS: cAMP has distinct acute and chronic effects on aquaporin-5 in lung epithelial cells. J Biol Chem 280: 3590-3596, 2005. (Pubitemid 40223825)
39. Dibas A, Yang MH, He S, Bobich J and Yorio T: Changes in ocular aquaporin-4 (AQP4) expression following retinal injury. Mol Vis 14: 1770-1783, 2008.
40. Kamsteeg EJ, Hendriks G, Boone M, Konings IBM, Oorschot V, van der Sluijs P, Klumperman J and Deen PM: Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel. Proc Natl Acad Sci USA 103: 18344-18349, 2006. (Pubitemid 44871660)
41. Leitch V, Agre P and King LS: Altered ubiquitination and stability of aquaporin-1 in hypertonic stress. Proc Natl Acad Sci USA 98: 2894-2898, 2001. (Pubitemid 32209580)
42. Schweitzer K, Li E, Sidhaye V, Leitch V, Kuznetsov S and King LS: Accumulation of aquaporin-1 during hemolysin-induced necrotic cell death. Cell Mol Biol Lett 13: 195-211, 2008.
43. Fernandes AF, Guo W, Zhang X, Gallagher M, Ivan M, Taylor A, Pereira P and Shang F: Proteasome-dependent regulation of signal transduction in retinal pigment epithelial cells. Exp Eye Res 83: 1472-1481, 2006. (Pubitemid 44648107)
44. Asher G, Tsvetkov P, Kahana C and Shaul Y: A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73. Genes Dev 19: 316-321, 2005. (Pubitemid 40189294)
45. Ito T, Fujio Y, Takahashi K and Azuma J: Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes. J Biol Chem 282: 1152-1160, 2007. (Pubitemid 47076570)
46. Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ and O'Malley BW: The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell 124: 381-392, 2006. (Pubitemid 43121985)
47. Murakami Y, Matsufuji S, Kameji T, Hayashi S, Igarashi K, Tamura T, Tanaka K and Ichihara A: Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. Nature 360: 597-599, 1992. (Pubitemid 23000711)
48. Poizat C, Sartorelli V, Chung G, Kloner RA and Kedes L: Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription. Mol Cell Biol 20: 8643-8654, 2000. (Pubitemid 32245898)
49. Sheaff RJ, Singer JD, Swanger J, Smitherman M, Roberts JM and Clurman BE: Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination. Mol Cell 5: 403-410, 2000. (Pubitemid 30628097)