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Volumn 9, Issue 7, 2014, Pages

Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ANTIARRHYTHMIC AGENT; CALCIUM ION; P21 ACTIVATED KINASE 1; PAK ACTIVATING PEPTIDE; UNCLASSIFIED DRUG; P21 ACTIVATED KINASE; PEPTIDE;

EID: 84904246339     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101974     Document Type: Article
Times cited : (27)

References (20)
  • 1
    • 34547665415 scopus 로고    scopus 로고
    • Small-molecule therapies for cardiac hypertrophy: Moving beneath the cell surface
    • DOI 10.1038/nrd2193, PII NRD2193
    • McKinsey TA, Kass DA (2007) Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface. Nat Rev Drug Discov 6: 617-635. (Pubitemid 47207749)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.8 , pp. 617-635
    • McKinsey, T.A.1    Kass, D.A.2
  • 2
    • 1042279545 scopus 로고    scopus 로고
    • 21-Activated Kinase-1 (Pak1) in Cardiac Myocytes
    • DOI 10.1161/01.RES.0000111522.02730.56
    • Ke Y, Wang L, Pyle WG, de Tombe PP, Solaro RJ (2004) Intracellular Localization and Functional Effects of P21-Activated Kinase-1 (Pak1) in Cardiac Myocytes. Circ Res 94: 194-200. (Pubitemid 38197451)
    • (2004) Circulation Research , vol.94 , Issue.2 , pp. 194-200
    • Ke, Y.1    Wang, L.2    Pyle, W.G.3    De Tombe, P.P.4    Solaro, R.J.5
  • 4
    • 62149110423 scopus 로고    scopus 로고
    • Regulation of cardiac excitation and contraction by p21 activated kinase-1
    • Ke Y, Lei M, Solaro RJ (2008) Regulation of cardiac excitation and contraction by p21 activated kinase-1. Prog Biophys Mol Biol 98: 238-250.
    • (2008) Prog Biophys Mol Biol , vol.98 , pp. 238-250
    • Ke, Y.1    Lei, M.2    Solaro, R.J.3
  • 6
    • 83455168963 scopus 로고    scopus 로고
    • PAK1 is a novel signal transducer attenuating cardiac hypertrophy
    • 2702-2715
    • Liu W, Min Z, Naumann R, Ke Y, Ulm S, et al. (2011) PAK1 is a novel signal transducer attenuating cardiac hypertrophy. Circulation 124(24):2702-15: 2702-2715.
    • (2011) Circulation , vol.124 , Issue.24 , pp. 2702-2715
    • Liu, W.1    Min, Z.2    Naumann, R.3    Ke, Y.4    Ulm, S.5
  • 7
    • 80055121231 scopus 로고    scopus 로고
    • Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A
    • Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, et al. (2011) Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A. J Mol Cell Cardiol 51: 988-996.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 988-996
    • Taglieri, D.M.1    Monasky, M.M.2    Knezevic, I.3    Sheehan, K.A.4    Lei, M.5
  • 8
    • 0032564383 scopus 로고    scopus 로고
    • Sudden cardiac death
    • Zipes DP, Wellens HJJ (1998) Sudden Cardiac Death. Circulation 98: 2334-2351. (Pubitemid 28533855)
    • (1998) Circulation , vol.98 , Issue.21 , pp. 2334-2351
    • Zipes, D.P.1    Wellens, H.J.J.2
  • 9
    • 0032979852 scopus 로고    scopus 로고
    • Mechanisms of remodeling of gap junction distributions and the development of anatomic substrates of arrhythmias
    • DOI 10.1016/S0008-6363(99)00023-1, PII S0008636399000231
    • Saffitz JE, Schuessler RB, Yamada KA (1999) Mechanisms of remodeling of gap junction distributions and the development of anatomic substrates of arrhythmias. Cardiovasc Res 42: 309-317. (Pubitemid 29243159)
    • (1999) Cardiovascular Research , vol.42 , Issue.2 , pp. 309-317
    • Saffitz, J.E.1    Schuessler, R.B.2    Yamada, K.A.3
  • 10
    • 61949425807 scopus 로고    scopus 로고
    • Gap Junction Remodeling and Spironolactone-Dependent Reverse Remodeling in the Hypertrophied Heart
    • Qu J, Volpicelli FM, Garcia LI, Sandeep N, Zhang J, et al. (2009) Gap Junction Remodeling and Spironolactone-Dependent Reverse Remodeling in the Hypertrophied Heart. Circ Res 104: 365-371.
    • (2009) Circ Res , vol.104 , pp. 365-371
    • Qu, J.1    Volpicelli, F.M.2    Garcia, L.I.3    Sandeep, N.4    Zhang, J.5
  • 12
    • 43549098268 scopus 로고    scopus 로고
    • Calcium cycling and signaling in cardiac myocytes
    • Bers DM (2008) Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol. 70: 23-49.
    • (2008) Annu Rev Physiol , vol.70 , pp. 23-49
    • Bers, D.M.1
  • 13
    • 27744437045 scopus 로고    scopus 로고
    • Production and use of a cell permeable inhibitor of group a Paks (TAT-PID) to analyze signal transduction
    • DOI 10.1016/j.ymeth.2005.05.017, PII S1046202305001362, GTPases
    • Beeser A, Chernoff J (2005) Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction. Methods 37: 203-207. (Pubitemid 41587430)
    • (2005) Methods , vol.37 , Issue.2 , pp. 203-207
    • Beeser, A.1    Chernoff, J.2
  • 14
    • 33947212877 scopus 로고    scopus 로고
    • The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity
    • Thullberg M, Gad A, Beeser A, Chernoff J, Stromblad S (2006) The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity. Oncogene 26: 1820-1828.
    • (2006) Oncogene , vol.26 , pp. 1820-1828
    • Thullberg, M.1    Gad, A.2    Beeser, A.3    Chernoff, J.4    Stromblad, S.5
  • 15
    • 79960228959 scopus 로고    scopus 로고
    • Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
    • Delorme-Walker VD, Peterson JR, Chernoff J, Waterman CM, Danuser G, et al. (2011) Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration. J Cell Biol 193: 1289-1303.
    • (2011) J Cell Biol , vol.193 , pp. 1289-1303
    • Delorme-Walker, V.D.1    Peterson, J.R.2    Chernoff, J.3    Waterman, C.M.4    Danuser, G.5
  • 17
    • 33947212877 scopus 로고    scopus 로고
    • The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity
    • DOI 10.1038/sj.onc.1209983, PII 1209983
    • Thullberg M, Gad A, Beeser A, Chernoff J, Stromblad S (2007) The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity. Oncogene 26: 1820-1828. (Pubitemid 46426207)
    • (2007) Oncogene , vol.26 , Issue.12 , pp. 1820-1828
    • Thullberg, M.1    Gad, A.2    Beeser, A.3    Chernoff, J.4    Stromblad, S.5
  • 18
    • 0033035644 scopus 로고    scopus 로고
    • Regression of left ventricular hypertrophy; What are appropriate therapeutic objectives?
    • DOI 10.1046/j.1365-2125.1999.00871.x
    • Sheridan DJ, Kingsbury MP, Flores NA (1999) Regression of left ventricular hypertrophy; what are appropriate therapeutic objectives? Br J Clin Pharmacol 47: 125-130. (Pubitemid 29078010)
    • (1999) British Journal of Clinical Pharmacology , vol.47 , Issue.2 , pp. 125-130
    • Sheridan, D.J.1    Kingsbury, M.P.2    Flores, N.A.3
  • 19
    • 80052897334 scopus 로고    scopus 로고
    • Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43
    • Ai X, Jiang A, Ke Y, Solaro RJ, Pogwizd SM (2011) Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43. Cardiovasc Res 92: 106-114.
    • (2011) Cardiovasc Res , vol.92 , pp. 106-114
    • Ai, X.1    Jiang, A.2    Ke, Y.3    Solaro, R.J.4    Pogwizd, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.