Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

Nature

Volumn 513, Issue 7518, 2014, Pages 431-435

  Zhang, Qingfeng ^a,b,c   Siegel, T Nicolai ^b,c,g   Martins, Rafael M ^b,c   Wang, Fei ^a   Cao, Jun ^d   Gao, Qi ^d   Cheng, Xiu ^e   Jiang, Lubin ^e   Hon, Chung Chau ^b   Scheidig Benatar, Christine ^b,c   Sakamoto, Hiroshi ^b,c   Turner, Louise ^f   Jensen, Anja T R ^f   Claes, Aurelie ^b,c   Guizetti, Julien ^b,c   Malmquist, Nicholas A ^b,c   Scherf, Artur ^b,c  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b INSTITUT PASTEUR   (France)

^c CNRS   (France)

^d JIANGSU INSTITUTE OF PARASITIC DISEASES   (China)

^e INSTITUTE PASTEUR OF SHANGHAI   (China)

^f University of Copenhagen   (Denmark)

^g UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROCYTE MEMBRANE PROTEIN 1; EXORIBONUCLEASE; LONG UNTRANSLATED RNA; PFRNASE II; PROTEIN; UNCLASSIFIED DRUG; UPSA PROTEIN; UPSC PROTEIN; EXORIBONUCLEASE II; MESSENGER RNA; PROTOZOAL PROTEIN; PROTOZOAL RNA; UNTRANSLATED RNA; VIRULENCE FACTOR;

ALLELE; ANTIBODY; BIODEGRADATION; CHROMOSOME; ENZYME ACTIVITY; GENE EXPRESSION; HOST-PARASITE INTERACTION; IMMUNE SYSTEM; MALARIA; MORTALITY; PROTEIN; PROTOZOAN; RNA;

ALLELE; ANTIGENIC VARIATION; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EPIGENETICS; ERYTHROCYTE MEMBRANE; GENE CONTROL; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INTRON; MALARIA FALCIPARUM; MORTALITY; PARASITE; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RNA DEGRADATION; RNA GENE; RNA TRANSCRIPTION; TRANSCRIPTION INITIATION SITE; CHROMATIN; DOWN REGULATION; ENZYMOLOGY; ERYTHROCYTE; GENE; GENETICS; MALARIA; METABOLISM; PARASITOLOGY; PATHOGENICITY; VIRULENCE;

PLASMODIUM FALCIPARUM;

ALLELES; ANTIGENIC VARIATION; CHROMATIN; DOWN-REGULATION; ERYTHROCYTES; EXORIBONUCLEASES; GENE SILENCING; GENES, PROTOZOAN; HUMANS; INTRONS; MALARIA, CEREBRAL; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PROMOTER REGIONS, GENETIC; PROTOZOAN PROTEINS; RNA, MESSENGER; RNA, PROTOZOAN; RNA, UNTRANSLATED; TRANSCRIPTION INITIATION SITE; VIRULENCE; VIRULENCE FACTORS;

EID: 84904244260     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13468     Document Type: Article

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