Two amino acid residues confer different binding affinities of abelson family kinase Src homology 2 domains for phosphorylated cortactin

Journal of Biological Chemistry

Volumn 289, Issue 28, 2014, Pages 19704-19713

  Gifford, Stacey M ^a   Liu, Weizhi ^b,e   Mader, Christopher C ^b   Halo, Tiffany L ^a   Machida, Kazuya ^d   Boggon, Titus J ^b,c   Koleske, Anthony J ^a,b,c  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE CANCER CENTER   (United States)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^e OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; ENZYMES; SUBSTRATES;

AMINO ACID RESIDUES; AMINO ACID SEQUENCE; BINDING AFFINITIES; DIFFERENT SUBSTRATES; DIFFERENTIAL INTERACTION; N-TERMINAL SEQUENCES; SRC HOMOLOGY 2 DOMAINS; STRUCTURAL COMPARISON;

POLYPEPTIDES;

ABELSON KINASE; ALANINE; AMINO ACID; CORTACTIN; LEUCINE; PROTEIN SH2; THREONINE; TYROSINE;

ANISOTROPY; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL EDGE PROTRUSION; CELL INTERACTION; CONTROLLED STUDY; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; FIBROBLAST; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; STRUCTURE ANALYSIS;

ACTIN; CRYSTAL STRUCTURE; PHOSPHOTYROSINE; SRC HOMOLOGY 2 DOMAIN (SH2 DOMAIN); TYROSINE-PROTEIN KINASE (TYROSINE KINASE);

AMINO ACID SUBSTITUTION; ANIMALS; CELLS, CULTURED; CORTACTIN; CRYSTALLOGRAPHY, X-RAY; FIBROBLASTS; HUMANS; MICE; MICE, KNOCKOUT; MUTATION, MISSENSE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-ABL; SRC HOMOLOGY DOMAINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84904200573     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.556480     Document Type: Article

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