Xanthium strumarium L. Extracts produce DNA damage mediated by cytotoxicity in in vitro assays but does not induce micronucleus in mice

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Piloto Ferrer, Janet ^a   Cozzi, Renata ^b   Cornetta, Tommaso ^b   Stano, Pasquale ^b   Fiore, Mario ^c   Degrassi, Francesca ^c   De Salvia, Rosella ^c   Remigio, Antonia ^a   Francisco, Marbelis ^a   Quiñones, Olga ^a   Valdivia, Dayana ^a   González, Maria L ^a   Pérez, Carlos ^d   Sánchez Lamar, Angel ^e  

^a CENTRO DE INVESTIGACIÓN Y DESARROLLO DE MEDICAMENTOS CIDEM   (Cuba)

^b ROMA TRE UNIVERSITY   (Italy)

^c CNR   (Italy)

^d INSTITUTO DE CIENCIAS BÁSICAS Y PRECLÍNICAS VICTORIA DE GIRÓN   (Cuba)

^e UNIVERSITY OF HAVANA   (Cuba)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUGEN; CLASTOGEN; PLANT EXTRACT; UNCLASSIFIED DRUG; XANTHIUM STRUMARIUM PLANT EXTRACT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BONE MARROW; BONE MARROW CELL; CELL VIABILITY; CHO CELL LINE; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENOTOXICITY; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME METABOLISM; METABOLIC ACTIVATION; MICRONUCLEUS; MICRONUCLEUS TEST; MITOSIS INDEX; MOUSE; MTT ASSAY; MUTAGENICITY; NONHUMAN; SALMONELLA TYPHIMURIUM; SISTER CHROMATID EXCHANGE; XANTHIUM STRUMARIUM; ANIMAL; CHEMISTRY; CRICETULUS; DRUG EFFECTS; RAT; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; XANTHIUM;

ANIMALS; CHO CELLS; CRICETULUS; DNA DAMAGE; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; PLANT EXTRACTS; RATS; SALMONELLA TYPHIMURIUM; XANTHIUM;

EID: 84904128072     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/575197     Document Type: Article

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