메뉴 건너뛰기




Volumn 60, Issue , 2014, Pages 343-348

Optimization of ginseng cell culture in airlift bioreactors and developing the large-scale production system

Author keywords

Airlift bioreactors; Ginseng; Ginsenosides; Pilot scale cultures; Suspension cultures

Indexed keywords

BIOCONVERSION; BIOMASS; BIOREACTORS; CELL CULTURE; SANDWICH STRUCTURES;

EID: 84904125972     PISSN: 09266690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.indcrop.2014.06.036     Document Type: Article
Times cited : (34)

References (32)
  • 1
    • 51349106992 scopus 로고    scopus 로고
    • Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C. A. Meyer
    • Choi K.T. Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C. A. Meyer. Acta Pharmacol. Sin. 2008, 29:1109-1118.
    • (2008) Acta Pharmacol. Sin. , vol.29 , pp. 1109-1118
    • Choi, K.T.1
  • 3
    • 84891101191 scopus 로고    scopus 로고
    • Production of biomass and bioactive compounds in protocorm cultures of Dendrobium candidum Wall ex Lindl. using balloon type bubble bioreactors
    • Cui Y.C., Murthy H.N., Moh S.H., Cui Y.Y., Lee E.J., Paek K.Y. Production of biomass and bioactive compounds in protocorm cultures of Dendrobium candidum Wall ex Lindl. using balloon type bubble bioreactors. Ind. Crops Prod. 2014, 53:28-33.
    • (2014) Ind. Crops Prod. , vol.53 , pp. 28-33
    • Cui, Y.C.1    Murthy, H.N.2    Moh, S.H.3    Cui, Y.Y.4    Lee, E.J.5    Paek, K.Y.6
  • 4
    • 80053100999 scopus 로고    scopus 로고
    • Production of adventitious root biomass and secondary metabolites of Hypericum perforatum L. in a balloon type airlift bioreactor
    • Cui X.H., Murthy H.N., Jin Y.X., Yim Y.H., Kim J.Y., Paek K.Y. Production of adventitious root biomass and secondary metabolites of Hypericum perforatum L. in a balloon type airlift bioreactor. Bioresour. Technol. 2011, 102:10072-10079.
    • (2011) Bioresour. Technol. , vol.102 , pp. 10072-10079
    • Cui, X.H.1    Murthy, H.N.2    Jin, Y.X.3    Yim, Y.H.4    Kim, J.Y.5    Paek, K.Y.6
  • 5
    • 33644523097 scopus 로고    scopus 로고
    • Growth and biosynthetic characteristics of ginseng (Panax japonicas var. repens) deep-tank cell culture in bioreactors
    • Demidova E.V., Reshetnyak O.V., Oreshnikov A.V., Nosov A.M. Growth and biosynthetic characteristics of ginseng (Panax japonicas var. repens) deep-tank cell culture in bioreactors. Russ. J. Plant Physiol. 2006, 53:134-140.
    • (2006) Russ. J. Plant Physiol. , vol.53 , pp. 134-140
    • Demidova, E.V.1    Reshetnyak, O.V.2    Oreshnikov, A.V.3    Nosov, A.M.4
  • 6
    • 84876455341 scopus 로고    scopus 로고
    • Effect of bioreactor angle and aeration rate on growth and hydromechanics parameters in bioreactor culture of ginseng suspension cells
    • Dong Y., Gao W.Y., Man S., Zuo B., Wang J., Huang L., Xiao P. Effect of bioreactor angle and aeration rate on growth and hydromechanics parameters in bioreactor culture of ginseng suspension cells. Acta Physiol. Plant 2013, 35:1497-1501.
    • (2013) Acta Physiol. Plant , vol.35 , pp. 1497-1501
    • Dong, Y.1    Gao, W.Y.2    Man, S.3    Zuo, B.4    Wang, J.5    Huang, L.6    Xiao, P.7
  • 7
    • 84885944173 scopus 로고    scopus 로고
    • Hosting plant cells in vitro: recent trends in bioreactors
    • Georgiev I.G., Eibl R., Zhong J.J. Hosting plant cells in vitro: recent trends in bioreactors. Appl. Microbiol. Biotechnol. 2013, 97:3787-3800.
    • (2013) Appl. Microbiol. Biotechnol. , vol.97 , pp. 3787-3800
    • Georgiev, I.G.1    Eibl, R.2    Zhong, J.J.3
  • 8
    • 0037416688 scopus 로고    scopus 로고
    • Effects of oxygen partial pressure on cell growth and ginsenoside and polysaccharide production in high density cell cultures of Panax notoginseng
    • Han J., Zhong J.J. Effects of oxygen partial pressure on cell growth and ginsenoside and polysaccharide production in high density cell cultures of Panax notoginseng. Enzyme Microb. Technol. 2003, 32:498-503.
    • (2003) Enzyme Microb. Technol. , vol.32 , pp. 498-503
    • Han, J.1    Zhong, J.J.2
  • 9
    • 62649118259 scopus 로고    scopus 로고
    • Application of an airlift bioreactor system for the production of adventitious root biomass and caffeic acid derivatives of Echinacea purpurea
    • Jeong J.A., Wu C.H., Murthy H.N., Hahn E.J., Paek K.Y. Application of an airlift bioreactor system for the production of adventitious root biomass and caffeic acid derivatives of Echinacea purpurea. Biotechnol. Bioprocess Eng. 2009, 14:91-98.
    • (2009) Biotechnol. Bioprocess Eng. , vol.14 , pp. 91-98
    • Jeong, J.A.1    Wu, C.H.2    Murthy, H.N.3    Hahn, E.J.4    Paek, K.Y.5
  • 10
    • 58149087508 scopus 로고    scopus 로고
    • Inoculum size and auxin concentration influence the growth of adventitious roots and accumulation of ginsenosides in suspension cultures of ginseng (Panax ginseng C. A. Meyer)
    • Jeong J.A., Murthy H.N., Hahn E.J., Paek K.Y. Inoculum size and auxin concentration influence the growth of adventitious roots and accumulation of ginsenosides in suspension cultures of ginseng (Panax ginseng C. A. Meyer). Acta Physiol. Plant 2009, 31:219-222.
    • (2009) Acta Physiol. Plant , vol.31 , pp. 219-222
    • Jeong, J.A.1    Murthy, H.N.2    Hahn, E.J.3    Paek, K.Y.4
  • 11
    • 0028815167 scopus 로고
    • Kinetic and stoichiometric analysis of hairy roots in a segmented bubble column reactor
    • Kwok K.H., Doran P.M. Kinetic and stoichiometric analysis of hairy roots in a segmented bubble column reactor. Biotechnol. Prog. 1995, 11:429-435.
    • (1995) Biotechnol. Prog. , vol.11 , pp. 429-435
    • Kwok, K.H.1    Doran, P.M.2
  • 12
    • 0033000090 scopus 로고    scopus 로고
    • Comparison of qualitative and quantitative in vitro ginsenoside production in callus cultures of three Panax species
    • Mathur A., Mathur A.K., Pal M., Uniyal G.C. Comparison of qualitative and quantitative in vitro ginsenoside production in callus cultures of three Panax species. Planta Med. 1999, 65:584-586.
    • (1999) Planta Med. , vol.65 , pp. 584-586
    • Mathur, A.1    Mathur, A.K.2    Pal, M.3    Uniyal, G.C.4
  • 13
    • 0028078394 scopus 로고
    • Saponin production in callus and cell suspension cultures of Panax quinquefolium
    • Mathur A., Shukla Y.N., Pal M., Ahuja P.S., Uniyal G.C. Saponin production in callus and cell suspension cultures of Panax quinquefolium. Phytochemistry 1994, 35:1221-1225.
    • (1994) Phytochemistry , vol.35 , pp. 1221-1225
    • Mathur, A.1    Shukla, Y.N.2    Pal, M.3    Ahuja, P.S.4    Uniyal, G.C.5
  • 14
    • 84982358134 scopus 로고
    • A revised medium for rapid growth and bioassay with tobacco tissue culture
    • Murashige T., Skoog F. A revised medium for rapid growth and bioassay with tobacco tissue culture. Physiol. Plant 1962, 15:473-497.
    • (1962) Physiol. Plant , vol.15 , pp. 473-497
    • Murashige, T.1    Skoog, F.2
  • 15
    • 84902333640 scopus 로고    scopus 로고
    • Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation
    • Murthy H.N., Lee E.J., Paek K.Y. Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation. Plant Cell Tissue Organ Cult. 2014, 10.1007/s11240-014-0467-7.
    • (2014) Plant Cell Tissue Organ Cult.
    • Murthy, H.N.1    Lee, E.J.2    Paek, K.Y.3
  • 17
    • 77955426593 scopus 로고    scopus 로고
    • Large scale culture of ginseng adventitious roots for production of ginsenosides
    • Paek K.Y., Murthy H.N., Hahn E.J., Zhong J.J. Large scale culture of ginseng adventitious roots for production of ginsenosides. Adv. Biochem. Eng. Biotechnol. 2009, 113:151-176.
    • (2009) Adv. Biochem. Eng. Biotechnol. , vol.113 , pp. 151-176
    • Paek, K.Y.1    Murthy, H.N.2    Hahn, E.J.3    Zhong, J.J.4
  • 18
    • 28644442090 scopus 로고    scopus 로고
    • Biological activities and chemistry of saponins from Panax ginseng C. A. Meyer
    • Park J.D., Rhee D.K., Lee Y.H. Biological activities and chemistry of saponins from Panax ginseng C. A. Meyer. Phytochem. Rev. 2005, 4:159-175.
    • (2005) Phytochem. Rev. , vol.4 , pp. 159-175
    • Park, J.D.1    Rhee, D.K.2    Lee, Y.H.3
  • 19
    • 0001259626 scopus 로고    scopus 로고
    • Recent studies on the biochemical constituents of Korean ginseng (Panax ginseng C. A. Meyer)
    • Park J.D. Recent studies on the biochemical constituents of Korean ginseng (Panax ginseng C. A. Meyer). Korean J. Ginseng Sci. 1996, 20:389-415.
    • (1996) Korean J. Ginseng Sci. , vol.20 , pp. 389-415
    • Park, J.D.1
  • 20
    • 22944489843 scopus 로고    scopus 로고
    • Production of rosmarinic acid by Lavandula vera cell suspension in bioreactor: effect of dissolved oxygen concentration and agitation
    • Pavlov A., Georgiev M.I., Ilieva M. Production of rosmarinic acid by Lavandula vera cell suspension in bioreactor: effect of dissolved oxygen concentration and agitation. World J. Microbiol. Biotechnol. 2005, 21:389-392.
    • (2005) World J. Microbiol. Biotechnol. , vol.21 , pp. 389-392
    • Pavlov, A.1    Georgiev, M.I.2    Ilieva, M.3
  • 21
    • 78649905100 scopus 로고    scopus 로고
    • Establishment of cell suspension cultures of Withania sominifera for the production of with anolide A
    • Praveen N., Murthy H.N. Establishment of cell suspension cultures of Withania sominifera for the production of with anolide A. Bioresour. Technol. 2010, 101:6735-6739.
    • (2010) Bioresour. Technol. , vol.101 , pp. 6735-6739
    • Praveen, N.1    Murthy, H.N.2
  • 22
    • 0023440316 scopus 로고
    • Effect of scale-up on serpentine formation by Catharanthus roseus suspension cultures
    • Scragg A.H., Morris P., Allan E.J., Bond P., Fowler M.W. Effect of scale-up on serpentine formation by Catharanthus roseus suspension cultures. Enzyme Microb. Technol. 1987, 9:619-624.
    • (1987) Enzyme Microb. Technol. , vol.9 , pp. 619-624
    • Scragg, A.H.1    Morris, P.2    Allan, E.J.3    Bond, P.4    Fowler, M.W.5
  • 23
    • 84903748372 scopus 로고    scopus 로고
    • Pilot-scale culture of somatic embryos of Eleutherococcus senticosus in airlift bioreactors for the production of eleutherosides
    • Shohael A.M., Murthy H.N., Paek K.Y. Pilot-scale culture of somatic embryos of Eleutherococcus senticosus in airlift bioreactors for the production of eleutherosides. Biotechnol. Lett. 2014, 10.1007/s10529-014-1534-1.
    • (2014) Biotechnol. Lett.
    • Shohael, A.M.1    Murthy, H.N.2    Paek, K.Y.3
  • 25
    • 33745673788 scopus 로고    scopus 로고
    • Effect of carbon dioxide on cell growth and saponin production in suspension cultures of Panax ginseng
    • Thanh N.T., Murthy H.N., Pandey D.M., Yu K.Y., Hahn E.J., Paek K.Y. Effect of carbon dioxide on cell growth and saponin production in suspension cultures of Panax ginseng. Biol. Plant 2006, 50:752-754.
    • (2006) Biol. Plant , vol.50 , pp. 752-754
    • Thanh, N.T.1    Murthy, H.N.2    Pandey, D.M.3    Yu, K.Y.4    Hahn, E.J.5    Paek, K.Y.6
  • 26
    • 33751176445 scopus 로고    scopus 로고
    • Effect of oxygen supply on cell growth and saponin production in bioreactor cultures of Panax ginseng
    • Thanh N.T., Murthy H.N., Yu K.W., Seung Jeong C., Hahn E.J., Paek K.Y. Effect of oxygen supply on cell growth and saponin production in bioreactor cultures of Panax ginseng. J. Plant Physiol. 2006, 163:1337-1341.
    • (2006) J. Plant Physiol. , vol.163 , pp. 1337-1341
    • Thanh, N.T.1    Murthy, H.N.2    Yu, K.W.3    Seung Jeong, C.4    Hahn, E.J.5    Paek, K.Y.6
  • 27
    • 84860369916 scopus 로고    scopus 로고
    • Effecting of medium composition on biomass and ginsenoside production in cell suspension culture of Panax vietnamensis Ha et Grushv
    • Thanh N.T., Ket N.V., Paek K.Y. Effecting of medium composition on biomass and ginsenoside production in cell suspension culture of Panax vietnamensis Ha et Grushv. VNU J Sci. Nat. Sci. Technol. 2007, 23:269-274.
    • (2007) VNU J Sci. Nat. Sci. Technol. , vol.23 , pp. 269-274
    • Thanh, N.T.1    Ket, N.V.2    Paek, K.Y.3
  • 28
    • 33745918648 scopus 로고    scopus 로고
    • Optimization of culturing conditions for the production of biomass and phenolics from adventitious roots of Echinacea angustifolia
    • Wu C.H., Dewir Y.H., Hahn E.J., Paek K.Y. Optimization of culturing conditions for the production of biomass and phenolics from adventitious roots of Echinacea angustifolia. J. Plant Biol. 2006, 49:193-199.
    • (2006) J. Plant Biol. , vol.49 , pp. 193-199
    • Wu, C.H.1    Dewir, Y.H.2    Hahn, E.J.3    Paek, K.Y.4
  • 29
    • 34447117110 scopus 로고    scopus 로고
    • Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid
    • Wu C.H., Murthy H.N., Hahn E.J., Paek K.Y. Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid. Biotechnol. Lett. 2007, 29:1179-1182.
    • (2007) Biotechnol. Lett. , vol.29 , pp. 1179-1182
    • Wu, C.H.1    Murthy, H.N.2    Hahn, E.J.3    Paek, K.Y.4
  • 30
    • 0033061525 scopus 로고    scopus 로고
    • Production of ginseng and its bioactive components in plant cell culture: current technological and applied aspects
    • Wu J., Zhong J.J. Production of ginseng and its bioactive components in plant cell culture: current technological and applied aspects. J. Biotechnol. 1999, 68:89-99.
    • (1999) J. Biotechnol. , vol.68 , pp. 89-99
    • Wu, J.1    Zhong, J.J.2
  • 31
    • 0034495024 scopus 로고    scopus 로고
    • Improvement of ginsenoside production by jasmonic acid and some other elicitors in hairy root cultures of ginseng (Panax ginseng C. A. Meyer)
    • Yu K.W., Gao W.Y., Son S.H., Paek K.Y. Improvement of ginsenoside production by jasmonic acid and some other elicitors in hairy root cultures of ginseng (Panax ginseng C. A. Meyer). In Vitro Cell. Dev. Biol. 2000, 36:424-428.
    • (2000) In Vitro Cell. Dev. Biol. , vol.36 , pp. 424-428
    • Yu, K.W.1    Gao, W.Y.2    Son, S.H.3    Paek, K.Y.4
  • 32
    • 0030574830 scopus 로고    scopus 로고
    • Effects of plant growth regulators on cell growth and ginsenoside sanponin production by suspension cultures of Panax quinquefolium
    • Zhong J.J., Bai Y., Wang S.J. Effects of plant growth regulators on cell growth and ginsenoside sanponin production by suspension cultures of Panax quinquefolium. J. Biotechnol. 1996, 45:227-234.
    • (1996) J. Biotechnol. , vol.45 , pp. 227-234
    • Zhong, J.J.1    Bai, Y.2    Wang, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.