VEGF, not VEGFR2, is associated with the angiogenesis effect of mini-TyrRS/mini-TrpRS in human umbilical vein endothelial cells in hypoxia

Cytotechnology

Volumn 66, Issue 4, 2014, Pages 655-665

  Zeng, Rui ^a   Jiang, Xiao Fei ^a   Chen, Yu Cheng ^a   Xu, Yuan Ning ^a   Ma, Song Hong ^a   Zeng, Zhi ^a   Liu, Rui ^b   Qiang, Ou ^b   Li, Xian ^b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Angiogenesis; HUVEC; Hypoxia; Mini TrpRS; Mini TyrRS; VEGF; VEGFR2

Indexed keywords

ANTIBODY; LENTIVIRUS VECTOR; MINI TRPRS PROTEIN; MINI TYRRS PROTEIN; PEPTIDE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; ASSAY; CELL HYPOXIA; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

LENTIVIRUS;

EID: 84904101938     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-013-9619-6     Document Type: Article

References (28)

1. Banik SD, Nandi N (2012) Mechanism of the activation step of the aminoacylation reaction: a significant difference between class I and class II synthetases. J Biomol Struct Dyn 30:701-715
2. Biselli PM, Guerzoni AR, de Godoy MF, Pavarino-Bertelli EC, Goloni-Bertollo EM (2008) Vascular endothelial growth factor genetic variability and coronary artery disease in Brazilian population. Heart Vessels 23:371-375
3. Brown JR, Doolittle WF (1995) Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications. Proc Natl Acad Sci USA 92:2441-2445
4. Brown JR, Robb FT, Weiss R, DoolittleWF(1997) Evidence for the early divergence of tryptophanyl- and tyrosyl-tRNA synthetases. J Mol Evol 45:9-16 (Pubitemid 27284333)
5. Choudhury A, Banerjee R (2013) The N-terminal fragment of Acanthamoeba polyphaga mimivirus tyrosyl-tRNA synthetase (TyrRSapm) is a monomer in solution. FEBS letter 587:590-599
6. Clark-Lewis I, Dewald B, Geiser T, Moser B, Baggiolini M (1993) Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg. Proc Natl Acad Sci USA 90:3574-3577 (Pubitemid 23111409)
7. Doublié S, Bricogne G, Gilmore C, Carter CW Jr (1995) Try-ptophanyl- tRNA synthetase crystal structure reveals an unexpected homology to tyrosyl-tRNA synthetase. Structure 3:17-31
8. Francklyn C, Perona JJ, Puetz J, Hou YM (2002) Aminoacyl-tRNA synthetases: versatile players in the changing theater of translation. RNA 8:1363-1372 (Pubitemid 35332960)
9. Fu G, Xu T, Shi Y, Wei N, Yang XL (2012) tRNA-controlled nuclear import of a human tRNA synthetase. J Biol Chem 287:9330-9334
10. Greenberg Y, King M, Kiosses WB, Ewalt K, Yang X, Schimmel P, Reader JS, Tzima E (2008) The novel fragment of tyrosyl tRNA synthetase, mini-TyrRS, is secreted to induce an angiogenic response in endothelial cells. FASEB J 25:1597-1605 (Pubitemid 351656799)
11. Jeong EJ, Hwang GS, Kim KH, Kim MJ, Kim S, Kim KS (2000) Structural analysis of multi-functional peptide motifs present in human bifunctional tRNA synthetase: identification of RNAbinding residues and functional implications for tandem repeats. Biochemistry 39:15775-15782 (Pubitemid 32038237)
12. Martinis SA, Plateau P, Cavarelli J, Florentz C (1999) Amino-acyl-tRNA synthetases: a family of expanding functions. Mittelwihr, France, October 10-15
13. Nagel GM, Doolittle RF (1995) Phylogenetic analysis of the aminoacyl-tRNA synthetases. J Mol Evol 40:487-498
14. Otani A, Slike BM, Dorrell MI, Hood J, Kinder K, Ewalt KL, Cheresh D, Schimmel P, Friedlander M (2002a) A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proc Natl Acad Sci USA 99:178-183 (Pubitemid 34060337)
15. Otani A, Kinder K, Ewalt K, Otero FJ, Schimmel P, Friedlander M (2002b) Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis. Nat Med 8:1004-1010 (Pubitemid 35033705)
16. Ran X, Wang H, Chen Y, Zeng Z, Zhou Q, Zheng R, Sun J, Wang B, Lv X, Liang Y, Zhang K, Liu W (2010) Aqu-aporin-1 expression and angiogenesis in rabbit chronic myocardial ischemia is decreased by acetazolamide. Heart Vessels 25:237-247
17. Ribas de Pouplana L, Schimmel P (2001) Aminoacyl-tRNA synthetases: potential markers of genetic code development. Trends Biochem Sci 26:591-596 (Pubitemid 32925189)
18. Sajish M, Zhou Q, Kishi S, Valdez DM Jr, Kapoor M, Guo M, Lee S, Kim S, Yang XL, Schimmel P (2012) Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. Nat Chem Biol 8:547-554
19. Sladowski D, Steer SJ, Clothier RH, Balls M (1993) An improved MTT assay. J Immunol Methods 157:203-207 (Pubitemid 23028092)
20. Tzima E, Reader JS, Irani-Tehrani M, Ewalt KL, Schwartz MA, Schimmel P (2003) Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells. Proc Natl Acad Sci USA 100:14903-14907 (Pubitemid 37517989)
21. Wakasugi K, Schimmel P (1999a) Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science 284:147-151 (Pubitemid 29282068)
22. Wakasugi K, Schimmel P (1999b) Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase. J Biol Chem 274:23155-23159
23. Wakasugi K, Slike BM, Hood J, Ewalt KL, Cheresh DA, Schimmel P (2002a) Introduction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase. J Biol Chem 277:20124-20126 (Pubitemid 34967300)
24. Wakasugi K, Slike BM, Hood J, Otani A, Ewalt KL, Friedlander M, Cheresh DA, Schimmel P (2002b) A human aminoacyl-tRNA synthetase as a regulator of angiogenesis. Proc Natl Acad Sci USA 99:173-177 (Pubitemid 34060336)
25. Woese CR, Olsen GJ, Ibba M, Söll D (2000) Aminoacyl-tRNA synthetases, the genetic code, and the evolutionary process. Microbiol Mol Biol Rev 64:202-236 (Pubitemid 30143846)
26. Yeh CH, Peng HC, Huang TF (1998) Accutin, a new disintegrin, inhibits angiogenesis in vitro and in vivo by acting as integrin alphavbeta-antagonist and inducing apoptosis. Blood 92:3268-3276 (Pubitemid 28492334)
27. Zeng R, Chen YC, Zeng Z, Liu WQ, Jiang XF, Liu R, Qiang O, Li X (2011) Effect of mini-tyrosyl-tRNA synthetase/mini-tryptophanyl-tRNA synthetase on ischemic angiogenesis in rats: proliferation and migration of endothelial cells. Heart Vessels 26:69-80
28. Zeng R, Chen YC, Zeng Z, Liu XX, Liu R, Qiang O, Li X (2012) Inhibition of mini-TyrRS-induced angiogenesis response in endothelial cells by VE-cadherin-dependent mini-TrpRS. Heart Vessels 27:193-201