Association between apolipoprotein e genotype and cancer susceptibility: A meta-analysis

Journal of Cancer Research and Clinical Oncology

Volumn 140, Issue 7, 2014, Pages 1075-1085

  Anand, R ^a   Prakash, S S ^a   Veeramanikandan, R ^a   Kirubakaran, Richard ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Apolipoprotein E; Cancer; Carcinoma; Epidemiology; Genetic association; Malignancy; Meta analysis

Indexed keywords

APOLIPOPROTEIN E;

ALLELE; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER LOCALIZATION; CANCER SUSCEPTIBILITY; CAUCASIAN; COLORECTAL CANCER; ETHNICITY; GENOTYPE; HEAD AND NECK CARCINOMA; HUMAN; LIVER CANCER; META ANALYSIS; PRIORITY JOURNAL; PROSTATE CANCER; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; STUDY DESIGN;

APOLIPOPROTEINS E; CASE-CONTROL STUDIES; COHORT STUDIES; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; NEOPLASMS; RISK FACTORS;

EID: 84904097485     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-014-1634-2     Document Type: Article

References (54)

1. Ahn SJ, Kim DK, Kim S, Bae CB, Cho HJ, Kim HG, Kim YJ, Lee JH, Lee HJ, Lee MY, Kim KB, Cho JH, Cho SW, Cheong JY (2012) Association between apolipoprotein E genotype, chronic liver disease, and hepatitis B virus. Clin Mol Hepatol 18(3):295-301. doi:10.3350/cmh.2012.18.3.295
2. Benn M, Tybjaerg-Hansen A, Stender S, Frikke-Schmidt R, Nordestgaard BG (2011) Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study. J Natl Cancer Inst 103(6):508-519. doi:10.1093/jnci/djr008
3. Bhattacharjee PS, Huq TS, Mandal TK, Graves RA, Muniruzzaman S, Clement C, McFerrin HE, Hill JM (2011) A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis. PLoS ONE 6(1):e15905. doi:10.1371/journal.pone.0015905
4. Browning PJ, Roberts DD, Zabrenetzky V, Bryant J, Kaplan M, Washington RH, Panet A, Gallo RC, Vogel T (1994) Apolipoprotein E (ApoE), a novel heparin-binding protein inhibits the development of Kaposi's sarcoma-like lesions in BALB/c nu/nu mice. J Exp Med 180(5):1949-1954 (Pubitemid 24328585)
5. Butler WJ, Ryan P, Roberts-Thomson IC (2001) Metabolic genotypes and risk for colorectal cancer. J Gastroenterol Hepatol 16(6):631-635 (Pubitemid 34188837)
6. Chang NW, Chen DR, Wu CT, Aouizerat BE, Chen FN, Hung SJ, Wang SH, Wei MF, Chang CS (2005) Influences of apolipoprotein E polymorphism on the risk for breast cancer and HER2/neu status in Taiwan. Breast Cancer Res Treat 90(3):257-261. doi:10.1007/s10549-004-4656-7 (Pubitemid 40576839)
7. Chang SJ, Hou MF, Tsai SM, Kao JT, Wu SH, Hou LA, Tsai LY (2006) Association between the apolipoprotein E genotypes and breast cancer patients in Taiwanese. Breast Cancer Res Treat 98(1):109-113. doi:10.1007/s10549-005-9137-0 (Pubitemid 44050785)
8. De Feo E, Rowell J, Cadoni G, Nicolotti N, Arzani D, Giorgio A, Amore R, Paludetti G, Ricciardi G, Boccia S (2010) A case-control study on the effect of apolipoprotein E genotype on head and neck cancer risk. Cancer Epidemiol Biomark Prev 19(11):2839-2846. doi:10.1158/1055-9965.EPI-10-0624
9. De Feo E, Simone B, Persiani R, Cananzi F, Biondi A, Arzani D, Amore R, D'Ugo D, Ricciardi G, Boccia S (2012) A casecontrol study on the effect of Apolipoprotein E genotypes on gastric cancer risk and progression. BMC Cancer 12:494. doi:10.1186/1471-2407-12-494
10. Deeks JJ, Higgins JPT, Altman DG (2008) Analysing data and undertaking meta-analyses. In: Cochrane handbook for systematic reviews of interventions. Wiley, pp 243-296. doi:10.1002/9780470712184.ch9
11. Driver JA, Beiser A, Au R, Kreger BE, Splansky GL, Kurth T, Kiel DP, Lu KP, Seshadri S, Wolf PA (2012) Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study. BMJ 344:e1442
12. Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM (1997) Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 278(16):1349-1356 (Pubitemid 27449696)
13. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schünemann HJ (2008) GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336(7650):924-926. doi:10.1136/bmj.39489.470347.AD (Pubitemid 351632017)
14. Ha SA, Shin SM, Kim HK, Kim S, Namkoong H, Lee YS, Kim HJ, Jung SM, Chung YJ, Park YG, Jung S, Kim JW (2009) Dual action of apolipoprotein E-interacting HCCR-1 oncoprotein and its implication for breast cancer and obesity. J Cell Mol Med 13(9B):3868-3875. doi:10.1111/j.1582-4934.2009.00652.x
15. Haapala K, Lehtimaki T, Ilveskoski E, Koivisto PA (2000) Apolipoprotein E genotype is not linked to locally recurrent hormone-refractory prostate cancer. Prostate Cancer Prostatic Dis 3(2):107-109. doi:10.1038/sj.pcan.45004054500405 (Pubitemid 30663594)
16. Higgins JP, Green S (2008) Cochrane handbook for systematic reviews of interventions: Cochrane Book Series. Wiley. doi:10.1002/9780470712184
17. Hu Z, Hu X, Long J, Su L, Wei B (2013) XRCC1 polymorphisms and differentiated thyroid carcinoma risk: a meta-analysis. Gene 528(2):67-73. doi:10.1016/j.gene.2013.07.005
18. Ioannidis JP, Boffetta P, Little J, O'Brien TR, Uitterlinden AG, Vineis P, Balding DJ, Chokkalingam A, Dolan SM, Flanders WD, Higgins JP, McCarthy MI, McDermott DH, Page GP, Rebbeck TR, Seminara D, Khoury MJ (2008) Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol 37:120-132 (Pubitemid 351228620)
19. Jacobs D, Blackburn H, Higgins M, Reed D, Iso H, McMillan G, Neaton J, Nelson J, Potter J, Rifkind B et al (1992) Report of the conference on low blood cholesterol: mortality associations. Circulation 86(3):1046-1060
20. Jiang L, Fang X, Bao Y, Zhou JY, Shen XY, Ding MH, Chen Y, Hu GH, Lu YC (2013) Association between the XRCC1 polymorphisms and glioma risk: a meta-analysis of case-control studies. PLoS ONE 8(1):e55597. doi:10.1371/journal.pone.0055597
21. Kulminski AM, Ukraintseva SV, Arbeev KG, Manton KG, Oshima J, Martin GM, Il'yasova D, Yashin AI (2008) Health-protective and adverse effects of the apolipoprotein E epsilon2 allele in older men. J Am Geriatr Soc 56(3):478-483. doi:10.1111/j.1532-5415.2007.01574.x (Pubitemid 351327926)
22. Kulminski AM, Culminskaya I, Ukraintseva SV, Arbeev KG, Arbeeva L, Wu D, Akushevich I, Land KC, Yashin AI (2011) Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan. Aging Cell 10(3):533-541. doi:10.1111/j.1474-9726.2011.00689.x
23. Kulminski AM, Culminskaya I, Arbeev KG, Ukraintseva SV, Arbeeva L, Yashin AI (2013) Trade-off in the effect of the APOE gene on the ages at onset of cardiovascular disease and cancer across ages, gender, and human generations. Rejuvenation Res 16(1):28-34. doi:10.1089/rej.2012.1362
24. Law MR, Thompson SG (1991) Low serum cholesterol and the risk of cancer: an analysis of the published prospective studies. Cancer Causes Control 2(4):253-261
25. Luo CC, Li WH, Moore MN, Chan L (1986) Structure and evolution of the apolipoprotein multigene family. J Mol Biol 187(3):325-340 (Pubitemid 16083775)
26. Mahley RW (1988) Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240(4852):622-630
27. Mahley RW, Weisgraber KH, Huang Y (2009) Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS. J Lipid Res 50(Suppl):S183-S188. doi:10.1194/jlr.R800069-JLR200
28. Mastracci TL, Shadeo A, Colby SM, Tuck AB, O'Malley FP, Bull SB, Lam WL, Andrulis IL (2006) Genomic alterations in lobular neoplasia: a microarray comparative genomic hybridization signature for early neoplastic proliferation in the breast. Genes Chromosome Cancer 45(11):1007-1017. doi:10.1002/gcc.20368 (Pubitemid 44435535)
29. McDonald BC, Conroy SK, Smith DJ, West JD, Saykin AJ (2013) Frontal gray matter reduction after breast cancer chemotherapy and association with executive symptoms: a replication and extension study. Brain Behav Immun 30(Suppl):S117-S125. doi:10.1016/j.bbi.2012.05.007
30. Minelli C, Thompson JR, Abrams KR, Thakkinstian A, Attia J (2009) The quality of meta-analyses of genetic association studies: a review with recommendations. Am J Epidemiol 170(11):1333-1343. doi:10.1093/aje/kwp350
31. Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6(7):e1000097. doi:10.1371/journal.pmed.1000097
32. Moysich KB, Freudenheim JL, Baker JA, Ambrosone CB, Bowman ED, Schisterman EF, Vena JE, Shields PG (2000) Apolipoprotein E genetic polymorphism, serum lipoproteins, and breast cancer risk. Mol Carcinog 27(1):2-9. doi:10.1002/(SICI)1098-2744(200001)27:1〈2:AID-MC2〉3.0.CO;2- W (Pubitemid 30089997)
33. Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, Wang M, Sanson M, Abramowicz S, Welch C, Bochem AE, Kuivenhoven JA, Yvan-Charvet L, Tall AR (2011) ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice. J Clin Invest 121(10):4138-4149. doi:10.1172/JCI57559
34. Musicco M, Adorni F, Di Santo S, Prinelli F, Pettenati C, Caltagirone C, Palmer K, Russo A (2013) Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study. Neurology 81(4):322-328. doi:10.1212/WNL. 0b013e31829c5ec1
35. Pencheva N, Tran H, Buss C, Huh D, Drobnjak M, Busam K, Tavazoie SF (2012) Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis. Cell 151(5):1068-1082. doi:10.1016/j.cell.2012.10.028
36. Porrata-Doria T, Matta JL, Acevedo SF (2010) Apolipoprotein E Allelic Frequency Altered in Women with early-onset breast cancer. Breast Cancer (Auckl) 4:43-48
37. Saadat M (2012) Apolipoprotein E (APOE) polymorphisms and susceptibility to breast cancer: a meta-analysis. Cancer Res Treat 44(2):121-126. doi:10.4143/crt.2012.44.2.121
38. Sagoo GS, Little J, Higgins JP (2009) Systematic reviews of genetic association studies: Human Genome Epidemiology Network. PLoS Med 6(3):e28. doi:10.1371/journal.pmed.1000028
39. Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-MacLachlan DR, Alberts MJ et al (1993) Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43(8):1467-1472 (Pubitemid 23230526)
40. Seixas S, Trovoada MJ, Rocha J (1999) Haplotype analysis of the apolipoprotein E and apolipoprotein C1 loci in Portugal and Sao Tome e Principe (Gulf of Guinea): linkage disequilibrium evidence that APOE*4 is the ancestral APOE allele. Hum Biol 71(6):1001-1008
41. Singh PP, Singh M, Mastana S (2006) APOE distribution in world populations with new data from India and the UK. Ann Hum Biol 33(3):279-308. doi:10.1080/03014460600594513 (Pubitemid 44232589)
42. Slattery ML, Sweeney C, Murtaugh M, Ma KN, Potter JD, Levin TR, Samowitz W, Wolff R (2005) Associations between apoE genotype and colon and rectal cancer. Carcinogenesis 26(8):1422-1429. doi:10.1093/carcin/bgi088 (Pubitemid 41417885)
43. Souza DR, Nakazone MA, Pinhel MA, Alvares RM, Monaco AC, Pinheiro A, Barros CF, Cury PM, Cunrath GS, Netinho JG (2009) Association between apolipoprotein E genotype, serum lipids, and colorectal cancer in Brazilian individuals. Braz J Med Biol Res 42(5):397-403
44. Srivastava K, Srivastava A (2012) Comprehensive review of genetic association studies and meta-analyses on miRNA polymorphisms and cancer risk. PLoS ONE 7(11):e50966. doi:10.1371/journal.pone.0050966
45. Strasak AM, Pfeiffer RM, Brant LJ, Rapp K, Hilbe W, Oberaigner W, Lang S, Borena W, Concin H, Diem G, Ruttmann E, Glodny B, Pfeiffer KP, Ulmer H (2009) Time-dependent association of total serum cholesterol and cancer incidence in a cohort of 172,210 men and women: a prospective 19-year follow-up study. Ann Oncol 20(6):1113-1120. doi:10.1093/annonc/mdn736
46. Surekha D, Vishnupriya S, Sailaja K, Nageswararao D, Ragunadharao D (2008) Influence of Apolipoprotein E gene polymorphism on the risk for breast Cancer. Int J Hum Genet 8(3):277-282
47. van Dekken H, Alers JC, Riegman PH, Rosenberg C, Tilanus HW, Vissers K (2001) Molecular cytogenetic evaluation of gastric cardia adenocarcinoma and precursor lesions. Am J Pathol 158(6):1961-1967. doi:10.1016/S0002-9440(10) 64666-4 (Pubitemid 32545180)
48. Vogel T, Guo NH, Guy R, Drezlich N, Krutzsch HC, Blake DA, Panet A, Roberts DD (1994) Apolipoprotein E: a potent inhibitor of endothelial and tumor cell proliferation. J Cell Biochem 54(3):299-308. doi:10.1002/jcb.240540306 (Pubitemid 24097226)
49. Watson MA, Gay L, Stebbings WS, Speakman CT, Bingham SA, Loktionov A (2003) Apolipoprotein E gene polymorphism and colorectal cancer: gender-specific modulation of risk and prognosis. Clin Sci (Lond) 104(5):537-545. doi:10.1042/CS20020329 (Pubitemid 36628150)
50. Wessel N, Liestol K, Maehlen J, Brorson SH (2001) The apolipoprotein E epsilon4 allele is no risk factor for prostate cancer in the Norwegian population. Br J Cancer 85(9):1418. doi:10.1054/bjoc.2001.2098 (Pubitemid 33081942)
51. Xue H, Lu Y, Lin B, Chen J, Tang F, Huang G (2012) The effect of XPD/ERCC2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis. PLoS ONE 7(9):e43431. doi:10.1371/journal. pone.0043431
52. Yu W, Kanaan Y, Bae YK, Gabrielson E (2009) Chromosomal changes in aggressive breast cancers with basal-like features. Cancer Genet Cytogenet 193(1):29-37. doi:10.1016/j.cancergencyto.2009.03.017
53. Zannis VI, Nicolosi RJ, Jensen E, Breslow JL, Hayes KC (1985) Plasma and hepatic apoE isoproteins of nonhuman primates: Differences in apoE among humans, apes, and New and Old World monkeys. J Lipid Res 26(12):1421-1430 (Pubitemid 16189739)
54. Zhu H, Cao S, Liu Y, Ding X, Wu Q, Ma H (2013) Genetic polymorphisms of xeroderma pigmentosum group D and prostate cancer risk: a meta-analysis. J Cancer Res Ther 9(2):187-192. doi:10.4103/0973-1482.113345