Rocuronium blockade reversal with sugammadex vs. neostigmine: Randomized study in Chinese and Caucasian subjects

BMC Anesthesiology

Volumn 14, Issue 1, 2014, Pages

  Wu, Xinmin ^a   Oerding, Helle ^b   Liu, Jin ^c   Vanacker, Bernard ^d   Yao, Shanglong ^e   Dahl, Vegard ^f   Xiong, Lize ^g   Claudius, Casper ^h   Yue, Yun ⁱ   Huang, Yuguang ^j   Abels, Esther ^k   Rietbergen, Henk ^k   Woo, Tiffany ^l  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b LILLEBAELT HOSPITAL   (Denmark)

^c SICHUAN UNIVERSITY   (China)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^f VESTRE VIKEN HOSPITAL TRUST   (Norway)

^g FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^h HILLERØD HOSPITAL   (Denmark)

ⁱ CAPITAL MEDICAL UNIVERSITY   (China)

^j PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^k MSD   (Netherlands)

^l MERCK RESEARCH LABORATORIES   (United States)

more..

Author keywords

Caucasian; Chinese; Neostigmine; Neuromuscular blockade; Rocuronium; Sugammadex

Indexed keywords

ATROPINE; BUTORPHANOL; NEOSTIGMINE; PROPOFOL; REMIFENTANIL; ROCURONIUM; SUFENTANIL; SUGAMMADEX; TRAMADOL; ANDROSTANE DERIVATIVE; CHOLINERGIC RECEPTOR STIMULATING AGENT; GAMMA CYCLODEXTRIN DERIVATIVE; NEUROMUSCULAR BLOCKING AGENT;

ABDOMINAL PAIN; ADULT; ANESTHESIA COMPLICATION; ARTICLE; CAUCASIAN; CHINESE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DIZZINESS; DRUG BINDING; DRUG EFFICACY; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; ELECTRIC PERIPHERAL NERVE STIMULATOR; FATIGUE; FEMALE; GEOMETRY; HUMAN; HYPOTENSION; INSOMNIA; MAINTENANCE DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MUSCLE TWITCH; NAUSEA; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR MONITORING; ODYNOPHAGIA; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; UPPER ABDOMINAL PAIN; VAGINA BLEEDING; VOMITING; WOUND COMPLICATION; AGED; ANTAGONISTS AND INHIBITORS; ASIAN CONTINENTAL ANCESTRY GROUP; CLINICAL TRIAL; COMPARATIVE STUDY; MIDDLE AGED; PROCEDURES; TREATMENT OUTCOME;

ADULT; AGED; ANDROSTANOLS; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GAMMA-CYCLODEXTRINS; HUMANS; MALE; MIDDLE AGED; NEOSTIGMINE; NEUROMUSCULAR BLOCKADE; NEUROMUSCULAR NONDEPOLARIZING AGENTS; PARASYMPATHOMIMETICS; TREATMENT OUTCOME;

EID: 84904085633     PISSN: None     EISSN: 14712253     Source Type: Journal    
DOI: 10.1186/1471-2253-14-53     Document Type: Article

References (32)

1. Tramer MR, Fuchs-Buder T: Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. a systematic review. Br J Anaesth 1999, 82:379-386. 10.1093/bja/82.3.379
2. Murphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS: Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit. Anesth Analg 2008, 107:130-137. 10.1213/ane.0b013e31816d1268
3. Blobner M, Eriksson LI, Scholz J, Motsch J, Della Rocca G, Prins ME: Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial. Eur J Anaesthesiol 2010, 27:874-881. 10.1097/EJA.0b013e32833d56b7
4. Booij LHDJ, de Boer HD, van Egmond J: Reversal agents for nondepolarizing neuromuscular blockade: reasons for and development of a new concept. Semin Anesth Periop Med Pain 2002, 32:92-98.
5. Saarnivaara L, Simila M: Effects of four anticholinesterase-anticholinergic combinations and tracheal extubation on QTc interval of the ECG, heart rate and arterial pressure. Acta Anaethesiol Scand 1998, 42:460-463. 10.1111/j.1399-6576.1998.tb05142.x
6. Vanacker BF, Vermeyen KM, Struys MM, Rietbergen H, Vandermeersch E, Saldien V, Kalmar AF, Prins ME: Reversal of rocuronium induced neuromuscular block with the novel drug sugammadex is equally effective under maintenance anaesthesia with propofol or sevoflurane. Anaesth Analg 2007, 104:563-568. 10.1213/01.ane.0000231829.29177.8e
7. Khuenl-Brady KS, Wattwil M, Vanacker BF, Lora-Tamayo JI, Rietbergen H, Alvarez-Gomez JA: Sugammadex provides faster reversal of vecuronium-induced neuromuscular blockade compared with neostigmine: a multicenter, randomized, controlled trial. Anesth Analg 2010, 110:64-73. 10.1213/ane.0b013e3181ac53c3
8. Fuchs-Buder T, Claudius C, Skovgaard LT, Eriksson LI, Mirakhur RK, Viby-Mogensen J, 8th International Neuromuscular Meeting: Good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents II: the Stockholm revision. Acta Anaesthesiol Scand 2007, 51:789-808. 10.1111/j.1399-6576.2007.01352.x
9. Claudius C, Viby-Mogensen J: Acceleromyography for use in scientific and clinical practice: a systematic review of the evidence. Anesthesiology 2008, 108:1117-1140. 10.1097/ALN.0b013e318173f62f
10. Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N: Simplified risks score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology 1999, 91:693-700. 10.1097/00000542-199909000-00022
11. Sorgenfrei I, Norrild K, Larsen P, Stensballe J, Ostergaard D, Prins M, Viby-Mogensen J: Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study. Anesthesiology 2006, 104:667-674. 10.1097/00000542-200604000-00009
12. Suy K, Morias K, Cammu G, Hans P, van Duijnhoven WG, Heeringa M, Demeyer I: Effective reversal of moderate rocuronium- or vecuronium-induced neuromuscular block with sugammadex, a selective relaxant binding agent. Anesthesiology 2007, 106:283-288. 10.1097/00000542-200702000-00016
13. de Kam PJ, van Kuijk J, Prohn M, Thomsen T, Peeters P: Effects of sugammadex doses up to 32 mg/kg alone or in combination with rocuronium or vecuronium on QTc prolongation: a thorough QTc study. Clin Drug Investig 2010, 30:599-611. 10.2165/11537210-000000000-00000
14. Peeters PA, van den Heuvel MW, van Heumen E, Passier PC, Smeets JM, van Iersel T, Zwiers A: Safety, tolerability and pharmacokinetics of sugammadex using single high doses (up to 96 mg/kg) in healthy adult subjects: a randomized, double-blind, crossover, placebo-controlled, single-centre study. Clin Drug Investig 2010, 30:867-874. 10.1007/BF03256915
15. Menéndez-Ozcoidi L, Ortiz-Gómez JR, Olaguibel-Ribero JM, Salvador-Bravo MH: Allergy to low dose sugammadex. Anaesthesia 2011, 66:217-219. 10.1111/j.1365-2044.2010.06611.x
16. Godai K, Hasegawa-Moriyama M, Kuniyoshi T, Kakoi T, Ikoma K, Isowaki S, Matsunaga A, Kanmura Y: Three cases of suspected sugammadex-induced hypersensitivity reactions. Br J Anaesth 2012, 109:216-218. 10.1093/bja/aes137
17. Soria A, Motamed C, Gaouar H, Chemam S, Amsler E, Francès C: Severe reaction following sugammadex injection: hypersensitivity? J Investig Allergol Clin Immunol 2012, 22:382.
18. Bridion SmPC 2012 http://www.medicines.org.uk/emc/medicine/21299
19. Yousefshahi F, Anbarafshan M, Khashayar P: Dermal reaction and bigeminal premature ventricular contractions due to neostigmine: a case report. J Med Case Rep 2011,25(5):83.
20. Seed MJ, Ewan PW: Anaphylaxis caused by neostigmine. Anaesthesia 2000, 55:574-575. 10.1046/j.1365-2044.2000.01125.x
21. de Kam PJ, El Galta R, Kruithof AC, Fennema H, van Lierop MJ, Mihara K, Burggraaf J, Moerland M, Peeters P, Troyer MD: No clinically relevant interaction between sugammadex and aspirin on platelet aggregation and coagulation parameters. Int J Clin Pharmacol Ther 2013, 51:976-985. 10.5414/CP201970
22. de Kam PJ, Grobara P, Prohn M, Höppener F, Kluft C, Burggraaf J, Langdon RB, Peeters P: Effects of sugammadex on activated partial thromboplastin time and prothrombin time in healthy subjects. Int J Clin Pharmacol Ther 2014, 2014:2014. Epub ahead of print
23. Rahe-Meyer N, Schulman S, Klimscha W, Przemeck M, Blobner M, Wulf HF Fennema H: Sugammadex reversal of rocuronium- or vecuronium-induced neuromuscular blockade is not associated with an increased risk of either bleeding or blood loss compared with usual care. Anesth Analg 2013,116(Suppl 1):S-48.
24. Lee E, Ryan S, Birmingham B, Zalikowski J, March R, Ambrose H, Moore R, Lee C, Chen Y, Schneck D: Rosuvastatin pharmacokinetics and pharmaocogenetics in white and Asian subjects reading in the same environment. Clin Pharmacol Ther 2005, 78:330-341. 10.1016/j.clpt.2005.06.013
25. Liao JK: Safety and efficacy of statins in Asians. Am J Cardiol 2007, 99:410-414. 10.1016/j.amjcard.2006.08.051
26. Zhou HH, Adeoyin A, Wood AJ: Differing effect of atropine on heart rate in Chinese and white subjects. Clin Pharmacol Ther 1992, 52:120-124. 10.1038/clpt.1992.120
27. McGraw J, Waller D: Cytochrome P450 variations in different ethnic populations. Expert Opin Drug Metab Toxicol 2012, 8:371-382. 10.1517/17425255.2012.657626
28. Daily EB, Aquilante CL: Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies. Pharmacogenomics 2009, 10:1489-1510. 10.2217/pgs.09.82
29. Kumana CR, Lauder IJ, Chan M, Ko W, Lin HJ: Differences in diazepam pharmacokinetics in Chinese and white Caucasians-relation to body lipid stores. Eur J Clin Pharmacol 1987, 32:211-215. 10.1007/BF00542199
30. Collins LM, Bevan JC, Bevan DR, Villar GC, Kahwaji R, Smith MF, Donati F: The prolonged duration of rocuronium in Chinese patients. Anesth Analg 2000, 91:1526-1530. 10.1097/00000539-200012000-00042
31. Fisher DM: Clinical pharmacology of neuromuscular blocking agents. Am J Health Sys Pharm 1999,56(Suppl 1):S4-S9.
32. -1 reversal of deep rocuronium-induced neuromuscular blockade: a multicenter study in chinese and caucasian patients. J Anesth Clin Res 2014, 5:408.