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Volumn 28, Issue 4, 2014, Pages 455-464

Phytol, a diterpene alcohol, inhibits the inflammatory response by reducing cytokine production and oxidative stress

Author keywords

Anti inflammatory; Cytokine; Oxidative stress; Phytol

Indexed keywords

BRADYKININ; CARRAGEENAN; COMPOUND 48-80; GLUTATHIONE; HISTAMINE; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; PHYTOL; PROSTAGLANDIN E2; SEROTONIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CYTOKINE; PEROXIDASE;

EID: 84904068542     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/fcp.12049     Document Type: Article
Times cited : (192)

References (47)
  • 1
    • 47949133729 scopus 로고    scopus 로고
    • Inflammation
    • Weiss U. Inflammation. Nature (2008) 454 427.
    • (2008) Nature , vol.454 , pp. 427
    • Weiss, U.1
  • 2
    • 84869192775 scopus 로고    scopus 로고
    • Antiinflammatory and antinociceptive effects in mice of a sulfated polysaccharide fraction extracted from the marine red algae Gracilaria caudata
    • Chaves L.S., Nicolau L.A.D., Silva R.O. et al. Antiinflammatory and antinociceptive effects in mice of a sulfated polysaccharide fraction extracted from the marine red algae Gracilaria caudata. Immunopharmacol. Immunotoxicol. (2013) 35 93-100.
    • (2013) Immunopharmacol. Immunotoxicol. , vol.35 , pp. 93-100
    • Chaves, L.S.1    Nicolau, L.A.D.2    Silva, R.O.3
  • 3
    • 2442648975 scopus 로고    scopus 로고
    • A newly identified role for superoxide in inflammatory pain
    • Wang Z.Q., Porreca F., Cuzzocrea S. et al. A newly identified role for superoxide in inflammatory pain. J. Pharmacol. Exp. Ther. (2004) 309 869-878.
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 869-878
    • Wang, Z.Q.1    Porreca, F.2    Cuzzocrea, S.3
  • 4
    • 80052649010 scopus 로고    scopus 로고
    • Anti-inflammatory and antinociceptive activity of ouabain in mice
    • Vasconcelos D.I.B., Leite J.A., Carneiro L.T. et al. Anti-inflammatory and antinociceptive activity of ouabain in mice. Mediators Inflamm. (2011) 2011 1-11.
    • (2011) Mediators Inflamm. , vol.2011 , pp. 1-11
    • Vasconcelos, D.I.B.1    Leite, J.A.2    Carneiro, L.T.3
  • 6
    • 77956677070 scopus 로고    scopus 로고
    • Hypotensive action of naturally occurring diterpenes: a therapeutic promise for the treatment of hypertension
    • Tirapelli C.R., Ambrosio S.R., de Oliveira A.M., Tostes R.C. Hypotensive action of naturally occurring diterpenes: a therapeutic promise for the treatment of hypertension. Fitoterapia (2010) 81 690-702.
    • (2010) Fitoterapia , vol.81 , pp. 690-702
    • Tirapelli, C.R.1    Ambrosio, S.R.2    de Oliveira, A.M.3    Tostes, R.C.4
  • 7
    • 33947544247 scopus 로고    scopus 로고
    • Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism
    • Valério D.A., Cunha T.M., Arakawa N.S. et al. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. Eur. J. Pharmacol. (2007) 562 155-163.
    • (2007) Eur. J. Pharmacol. , vol.562 , pp. 155-163
    • Valério, D.A.1    Cunha, T.M.2    Arakawa, N.S.3
  • 8
    • 84879632350 scopus 로고    scopus 로고
    • Anti-inflammatory and antinociceptive activity of epiisopiloturine, an imidazole alkaloid isolated from Pilocarpus microphyllus
    • Silva V.G., Silva R.O., Damasceno S.R.B. et al. Anti-inflammatory and antinociceptive activity of epiisopiloturine, an imidazole alkaloid isolated from Pilocarpus microphyllus. J. Nat. Prod. (2013) 76 1071-1077.
    • (2013) J. Nat. Prod. , vol.76 , pp. 1071-1077
    • Silva, V.G.1    Silva, R.O.2    Damasceno, S.R.B.3
  • 9
    • 34250785114 scopus 로고    scopus 로고
    • The function of terpene natural products in the natural world
    • Gershenzon J., Dudareva N. The function of terpene natural products in the natural world. Nat. Chem. Biol. (2007) 3 408-414.
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 408-414
    • Gershenzon, J.1    Dudareva, N.2
  • 10
    • 84866765694 scopus 로고    scopus 로고
    • Chemical composition and biological activity of the essential oil from Jamaican Cleome serrata
    • Mcneil M.J., Porter R.B., Williams L.A. Chemical composition and biological activity of the essential oil from Jamaican Cleome serrata. Nat. Prod. Commun. (2012) 7 1231-1232.
    • (2012) Nat. Prod. Commun. , vol.7 , pp. 1231-1232
    • Mcneil, M.J.1    Porter, R.B.2    Williams, L.A.3
  • 11
    • 84868121447 scopus 로고    scopus 로고
    • Chemical characterization of volatile compounds of Lantana camara L. and L. radula Sw. and their antifungal activity
    • Passos J.L., Barbosa L.C., Demuner A.J., Alvarenga E.S., Silva C.M., Barreto R.W. Chemical characterization of volatile compounds of Lantana camara L. and L. radula Sw. and their antifungal activity. Molecules (2012) 17 11447-11455.
    • (2012) Molecules , vol.17 , pp. 11447-11455
    • Passos, J.L.1    Barbosa, L.C.2    Demuner, A.J.3    Alvarenga, E.S.4    Silva, C.M.5    Barreto, R.W.6
  • 12
    • 72249122947 scopus 로고    scopus 로고
    • Antitubercular potential of some semisynthetic analogues of phytol
    • Saikia D., Parihar S., Chanda D. et al. Antitubercular potential of some semisynthetic analogues of phytol. Bioorg. Med. Chem. Lett. (2010) 20 508-512.
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 508-512
    • Saikia, D.1    Parihar, S.2    Chanda, D.3
  • 14
    • 0026547038 scopus 로고
    • Antispasmodic activity of beta-damascenone and e-phytol isolated from Ipomoea pes-caprae
    • Pongprayoon U., Baeckström P., Jacobsson U., Lindström M., Bohlin L. Antispasmodic activity of beta-damascenone and e-phytol isolated from Ipomoea pes-caprae. Planta Med. (1992) 58 19-21.
    • (1992) Planta Med. , vol.58 , pp. 19-21
    • Pongprayoon, U.1    Baeckström, P.2    Jacobsson, U.3    Lindström, M.4    Bohlin, L.5
  • 15
    • 73349091965 scopus 로고    scopus 로고
    • Anticancer activity of phytol and eicosatrienoic acid identified from Perilla leaves
    • Lee K.L., Lee S.H., Park K.Y. Anticancer activity of phytol and eicosatrienoic acid identified from Perilla leaves. J. Korean Soc. Food Sci. Nutr. (1999) 28 1107-1112.
    • (1999) J. Korean Soc. Food Sci. Nutr. , vol.28 , pp. 1107-1112
    • Lee, K.L.1    Lee, S.H.2    Park, K.Y.3
  • 17
    • 0034814762 scopus 로고    scopus 로고
    • Cytotoxic and anti-inflammatory activity of labdane and cis-clerodane type diterpenes
    • Demetzos C., Dimas K., Hatziantoniou S., Anastasaki T., Angelopoulou D. Cytotoxic and anti-inflammatory activity of labdane and cis-clerodane type diterpenes. Planta Med. (2001) 67 614-618.
    • (2001) Planta Med. , vol.67 , pp. 614-618
    • Demetzos, C.1    Dimas, K.2    Hatziantoniou, S.3    Anastasaki, T.4    Angelopoulou, D.5
  • 18
    • 67249094291 scopus 로고
    • Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs
    • Winter C.A., Risley E.A., Nuss G.W. Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs. Proc. Soc. Exp. Biol. Med. (1962) 111 544-547.
    • (1962) Proc. Soc. Exp. Biol. Med. , vol.111 , pp. 544-547
    • Winter, C.A.1    Risley, E.A.2    Nuss, G.W.3
  • 19
    • 33745943970 scopus 로고    scopus 로고
    • Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema
    • Claudino R.F., Kassuya C.A., Ferreira J., Calixto J.B. Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema. J. Pharmacol. Exp. Ther. (2006) 318 611-618.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 611-618
    • Claudino, R.F.1    Kassuya, C.A.2    Ferreira, J.3    Calixto, J.B.4
  • 21
    • 84871740396 scopus 로고
    • Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent
    • Sedlak J., Lindsay R.H. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal. Biochem. (1968) 24 1992-2005.
    • (1968) Anal. Biochem. , vol.24 , pp. 1992-2005
    • Sedlak, J.1    Lindsay, R.H.2
  • 22
    • 0018069570 scopus 로고
    • Determination of malonaldehyde precursor in tissues by thiobarbituric acid test
    • Mihara M., Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. (1978) 86 271-278.
    • (1978) Anal. Biochem. , vol.86 , pp. 271-278
    • Mihara, M.1    Uchiyama, M.2
  • 23
    • 60749106386 scopus 로고    scopus 로고
    • Vernonia cinerea L. scavenges free radicals and regulates nitric oxide and proinflammatory cytokines profile in carrageenan induced paw edema model
    • Kumar P.P., Kuttan G. Vernonia cinerea L. scavenges free radicals and regulates nitric oxide and proinflammatory cytokines profile in carrageenan induced paw edema model. Immunopharmacol. Immunotoxicol. (2009) 31 94-102.
    • (2009) Immunopharmacol. Immunotoxicol. , vol.31 , pp. 94-102
    • Kumar, P.P.1    Kuttan, G.2
  • 25
    • 84874366766 scopus 로고    scopus 로고
    • A report of a galactan from marine alga Gelidium crinale with in vivo anti-inflammatory and antinociceptive effects
    • Sousa A.A., Benevides N.M., de Freitas P.A. et al. A report of a galactan from marine alga Gelidium crinale with in vivo anti-inflammatory and antinociceptive effects. Fundam. Clin. Pharmacol. (2013) 27 173-180.
    • (2013) Fundam. Clin. Pharmacol. , vol.27 , pp. 173-180
    • Sousa, A.A.1    Benevides, N.M.2    de Freitas, P.A.3
  • 27
    • 0030796054 scopus 로고    scopus 로고
    • Pro-inflammatory effects induced by bradykinin in a murine model of pleurisy
    • Saleh T.S.F., Calixto J.B., Medeiros Y.S. Pro-inflammatory effects induced by bradykinin in a murine model of pleurisy. Eur. J. Pharmacol. (1997) 331 43-52.
    • (1997) Eur. J. Pharmacol. , vol.331 , pp. 43-52
    • Saleh, T.S.F.1    Calixto, J.B.2    Medeiros, Y.S.3
  • 28
    • 4243552188 scopus 로고
    • Kinin mediators of intestinal secretion
    • Gaginella T.S., Kachur J.F. Kinin mediators of intestinal secretion. Am. J. Physiol. (1989) 256 1-15.
    • (1989) Am. J. Physiol. , vol.256 , pp. 1-15
    • Gaginella, T.S.1    Kachur, J.F.2
  • 29
    • 9944224285 scopus 로고    scopus 로고
    • 2α and prostaglandin E2 in carrageenan-induced air pouch model in rats
    • 2α and prostaglandin E2 in carrageenan-induced air pouch model in rats. Eur. J. Pharmacol. (2004) 506 189-197.
    • (2004) Eur. J. Pharmacol. , vol.506 , pp. 189-197
    • Özdöl, N.C.1    Melli, M.2
  • 30
    • 73449143528 scopus 로고    scopus 로고
    • Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease
    • Van Der Veen B.S., de Winther M.P., Heeringa P. Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease. Antioxid. Redox Signal. (2009) 11 2899-2937.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 2899-2937
    • Van Der Veen, B.S.1    de Winther, M.P.2    Heeringa, P.3
  • 31
    • 0035834065 scopus 로고    scopus 로고
    • Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis
    • Gaut J.P., Yeh G.C., Tran H.D. et al. Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis. Proc. Natl Acad. Sci. USA (2001) 98 11961-11966.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 11961-11966
    • Gaut, J.P.1    Yeh, G.C.2    Tran, H.D.3
  • 32
    • 0022538729 scopus 로고
    • Leukocyte recruitment in the subcutaneous sponge implant model of acute inflammation in the rat is not mediated by leukotriene B4
    • Foster S.J., McCormick M.E., Howarth A., Aked D. Leukocyte recruitment in the subcutaneous sponge implant model of acute inflammation in the rat is not mediated by leukotriene B4. Biochem. Pharmacol. (1986) 35 1709-1717.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 1709-1717
    • Foster, S.J.1    McCormick, M.E.2    Howarth, A.3    Aked, D.4
  • 33
    • 33846661966 scopus 로고    scopus 로고
    • Cytokine profiles during carrageen-induced inflammatory hyperalgesia in rat muscle and hind paw
    • Loram L.C., Fuller A., Fick L.G., Cartmell T., Poole S., Mitchell D. Cytokine profiles during carrageen-induced inflammatory hyperalgesia in rat muscle and hind paw. J. Pain (2007) 8 127-136.
    • (2007) J. Pain , vol.8 , pp. 127-136
    • Loram, L.C.1    Fuller, A.2    Fick, L.G.3    Cartmell, T.4    Poole, S.5    Mitchell, D.6
  • 34
    • 58149343686 scopus 로고    scopus 로고
    • Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-kβ inactivation
    • Yun K.J., Koh D.J., Kim S.H. et al. Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-kβ inactivation. J. Agric. Food Chem. (2008) 56 10265-10272.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 10265-10272
    • Yun, K.J.1    Koh, D.J.2    Kim, S.H.3
  • 35
    • 0001929693 scopus 로고    scopus 로고
    • Cytokines in acute and chronic inflammation
    • Feghali C.A., Wright T.M. Cytokines in acute and chronic inflammation. Front. Biosci. (1997) 1 12-26.
    • (1997) Front. Biosci. , vol.1 , pp. 12-26
    • Feghali, C.A.1    Wright, T.M.2
  • 36
    • 84879027507 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-oxidant activities of olmesartan medoxomil ameliorate experimental colitis in rats
    • Nagib M.M., Tadros M.G., ELSayed M.I., Khalifa A.E. Anti-inflammatory and anti-oxidant activities of olmesartan medoxomil ameliorate experimental colitis in rats. Toxicol. Appl. Pharmacol. (2013) 271 106-113.
    • (2013) Toxicol. Appl. Pharmacol. , vol.271 , pp. 106-113
    • Nagib, M.M.1    Tadros, M.G.2    ELSayed, M.I.3    Khalifa, A.E.4
  • 37
    • 77952568487 scopus 로고    scopus 로고
    • Correlation of seizures and biochemical parameters of oxidative stress in experimentally induced inflammatory rat models
    • Rao R.S., Medhi B., Khanduja K.L., Pandhi P. Correlation of seizures and biochemical parameters of oxidative stress in experimentally induced inflammatory rat models. Fundam. Clin. Pharmacol. (2010) 24 325-331.
    • (2010) Fundam. Clin. Pharmacol. , vol.24 , pp. 325-331
    • Rao, R.S.1    Medhi, B.2    Khanduja, K.L.3    Pandhi, P.4
  • 38
    • 0033990345 scopus 로고    scopus 로고
    • Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries
    • Bowie A., O'Neill L.A. Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries. Biochem. Pharmacol. (2000) 59 13-23.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 13-23
    • Bowie, A.1    O'Neill, L.A.2
  • 39
    • 0035095323 scopus 로고    scopus 로고
    • Antioxidants in health and disease
    • Young I.S., Woodside J.V. Antioxidants in health and disease. J. Clin. Pathol. (2001) 54 176-186.
    • (2001) J. Clin. Pathol. , vol.54 , pp. 176-186
    • Young, I.S.1    Woodside, J.V.2
  • 40
    • 0038342017 scopus 로고    scopus 로고
    • Oxidative stress, exercise, and antioxidant supplementation
    • Urso M.L., Clarkson P.M. Oxidative stress, exercise, and antioxidant supplementation. Toxicology (2003) 189 41-54.
    • (2003) Toxicology , vol.189 , pp. 41-54
    • Urso, M.L.1    Clarkson, P.M.2
  • 42
    • 73349137314 scopus 로고    scopus 로고
    • Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production
    • Valério D.A., Georgetti S.R., Magro D.A. et al. Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production. J. Nat. Prod. (2009) 72 1975-1979.
    • (2009) J. Nat. Prod. , vol.72 , pp. 1975-1979
    • Valério, D.A.1    Georgetti, S.R.2    Magro, D.A.3
  • 43
    • 78650723012 scopus 로고    scopus 로고
    • Analgesic effects and the mechanisms of anti-inflammation of hispolon in mice
    • Chang H.Y., Sheu M.J., Yang C.H. et al. Analgesic effects and the mechanisms of anti-inflammation of hispolon in mice. Evid. Based Complementary Altern. Med. (2011) 2011 1-8.
    • (2011) Evid. Based Complementary Altern. Med. , vol.2011 , pp. 1-8
    • Chang, H.Y.1    Sheu, M.J.2    Yang, C.H.3
  • 44
    • 74049087048 scopus 로고    scopus 로고
    • Thioctic acid protects against carrageenan-induced acute inflammation in rats by reduction in oxidative stress, downregulation of COX-2 mRNA and enhancement of IL-10 mRNA
    • El-Shitany N.A., El-Masry S.A., El-Ghareib M.A., El-Desoky K. Thioctic acid protects against carrageenan-induced acute inflammation in rats by reduction in oxidative stress, downregulation of COX-2 mRNA and enhancement of IL-10 mRNA. Fundam. Clin. Pharmacol. (2010) 24 91-99.
    • (2010) Fundam. Clin. Pharmacol. , vol.24 , pp. 91-99
    • El-Shitany, N.A.1    El-Masry, S.A.2    El-Ghareib, M.A.3    El-Desoky, K.4
  • 45
    • 84859763499 scopus 로고    scopus 로고
    • Anti-inflammatory activities of Cinnamomum cassia constituents in vitro and in vivo
    • Liao J.C., Deng J.S., Chiu C.S. et al. Anti-inflammatory activities of Cinnamomum cassia constituents in vitro and in vivo. Evid. Based Complementary Altern. Med. (2012) 2012 1-12.
    • (2012) Evid. Based Complementary Altern. Med. , vol.2012 , pp. 1-12
    • Liao, J.C.1    Deng, J.S.2    Chiu, C.S.3
  • 47
    • 84862279423 scopus 로고    scopus 로고
    • Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism
    • Uzkeser H., Cadirci E., Halici Z. et al. Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm. (2012) 2012 1-10.
    • (2012) Mediators Inflamm. , vol.2012 , pp. 1-10
    • Uzkeser, H.1    Cadirci, E.2    Halici, Z.3


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