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Volumn 24, Issue 4, 2014, Pages 388-396

Increased risk of developing cutaneous malignant melanoma is associated with variation in pigmentation genes and VDR, and may involve epistatic effects

Author keywords

association; cutaneous malignant melanoma; gene gene interactions; pigmentation genes; VDR

Indexed keywords

VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR; VDR PROTEIN, HUMAN;

EID: 84904066512     PISSN: 09608931     EISSN: 14735636     Source Type: Journal    
DOI: 10.1097/CMR.0000000000000095     Document Type: Article
Times cited : (21)

References (92)
  • 1
    • 78049520359 scopus 로고    scopus 로고
    • Estimating the attributable fraction for melanoma: A meta-analysis of pigmentary characteristics and freckling
    • Olsen CM, Carroll HJ, Whiteman DC. Estimating the attributable fraction for melanoma: a meta-analysis of pigmentary characteristics and freckling. Int J Cancer 2010; 127:2430-2445.
    • (2010) Int J Cancer , vol.127 , pp. 2430-2445
    • Olsen, C.M.1    Carroll, H.J.2    Whiteman, D.C.3
  • 2
    • 84869504616 scopus 로고    scopus 로고
    • International trends in the incidence of malignant melanoma 1953-2008 -are recent generations at higher or lower risk?
    • Erdmann F, Lortet-Tieulent J, Schüz J, Zeeb H, Greinert R, Breitbart EW, Bray F. International trends in the incidence of malignant melanoma 1953-2008-are recent generations at higher or lower risk? Int J Cancer 2013; 132:385-400.
    • (2013) Int J Cancer , vol.132 , pp. 385-400
    • Erdmann, F.1    Lortet-Tieulent, J.2    Schüz, J.3    Zeeb, H.4    Greinert, R.5    Breitbart, E.W.6    Bray, F.7
  • 4
    • 84859770439 scopus 로고    scopus 로고
    • A brief history of melanoma: From mummies to mutations
    • Rebecca VW, Sondak VK, Smalley KS. A brief history of melanoma: from mummies to mutations. Melanoma Res 2012; 22:114-122.
    • (2012) Melanoma Res , vol.22 , pp. 114-122
    • Rebecca, V.W.1    Sondak, V.K.2    Smalley, K.S.3
  • 5
    • 0035722059 scopus 로고    scopus 로고
    • Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color
    • Kennedy C, ter Huurne J, Berkhout M, Gruis N, Bastiaens M, Bergman W, et al. Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J Invest Dermatol 2001; 117:294-300.
    • (2001) J Invest Dermatol , vol.117 , pp. 294-300
    • Kennedy, C.1    Ter Huurne, J.2    Berkhout, M.3    Gruis, N.4    Bastiaens, M.5    Bergman, W.6
  • 6
    • 33746121511 scopus 로고    scopus 로고
    • Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population
    • Stratigos AJ, Dimisianos G, Nikolaou V, Poulou M, Sypsa V, Stefanaki I, et al. Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population. J Invest Dermatol 2006; 126:1842-1849.
    • (2006) J Invest Dermatol , vol.126 , pp. 1842-1849
    • Stratigos, A.J.1    Dimisianos, G.2    Nikolaou, V.3    Poulou, M.4    Sypsa, V.5    Stefanaki, I.6
  • 7
    • 58249125574 scopus 로고    scopus 로고
    • The contribution of melanocortin 1 receptor gene polymorphisms and the agouti signalling protein gene 8818A G polymorphism to cutaneous melanoma and basal cell carcinoma in a Polish population
    • Brudnik U, Branicki W, Wojas-Pelc A, Kanas P. The contribution of melanocortin 1 receptor gene polymorphisms and the agouti signalling protein gene 8818A G polymorphism to cutaneous melanoma and basal cell carcinoma in a Polish population. Exp Dermatol 2009; 18:167-174.
    • (2009) Exp Dermatol , vol.18 , pp. 167-174
    • Brudnik, U.1    Branicki, W.2    Wojas-Pelc, A.3    Kanas, P.4
  • 8
    • 0029839525 scopus 로고    scopus 로고
    • The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma
    • Valverde P, Healy E, Sikkink S, Haldane F, Thody AJ, Carothers A, et al. The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma. Hum Mol Genet 1996; 5:1663-1666.
    • (1996) Hum Mol Genet , vol.5 , pp. 1663-1666
    • Valverde, P.1    Healy, E.2    Sikkink, S.3    Haldane, F.4    Thody, A.J.5    Carothers, A.6
  • 9
    • 0033910271 scopus 로고    scopus 로고
    • MC1R polymorphisms and risk of melanoma is the association explained solely by pigmentation phenotype?
    • Palmer JS, Duffy DL, Box NF, Aitken JF, O'Gorman LE, Green AC, et al. MC1R polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype? Am J Hum Genet 2000; 66:176-186.
    • (2000) Am J Hum Genet , vol.66 , pp. 176-186
    • Palmer, J.S.1    Duffy, D.L.2    Box, N.F.3    Aitken, J.F.4    O'Gorman, L.E.5    Green, A.C.6
  • 11
    • 2342583510 scopus 로고    scopus 로고
    • Does the addition of information on genotype improve prediction of the risk of melanoma and nonmelanoma skin cancer beyond that obtained from skin phenotype?
    • Dwyer T, Stankovich JM, Blizzard L, FitzGerald LM, Dickinson JL, Reilly A, et al. Does the addition of information on genotype improve prediction of the risk of melanoma and nonmelanoma skin cancer beyond that obtained from skin phenotype? Am J Epidemiol 2004; 159:826-833.
    • (2004) Am J Epidemiol , vol.159 , pp. 826-833
    • Dwyer, T.1    Stankovich, J.M.2    Blizzard, L.3    Fitzgerald, L.M.4    Dickinson, J.L.5    Reilly, A.6
  • 13
    • 51549103690 scopus 로고    scopus 로고
    • Variants of the MATP/SLC45A2 gene are protective for melanoma in the French population
    • Melan Cohort Investigators
    • Guedj M, Bourillon A, Combadières C, Rodero M, Dieudé P, Descamps V, et al. Melan Cohort Investigators. Variants of the MATP/SLC45A2 gene are protective for melanoma in the French population. Hum Mutat 2008; 29:1154-1160.
    • (2008) Hum Mutat , vol.29 , pp. 1154-1160
    • Guedj, M.1    Bourillon, A.2    Combadières, C.3    Rodero, M.4    Dieudé, P.5    Descamps, V.6
  • 15
    • 81855199793 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel loci predisposing to cutaneous melanoma
    • Amos CI, Wang LE, Lee JE, Gershenwald JE, Chen WV, Fang S, et al. Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet 2011; 20:5012-5023.
    • (2011) Hum Mol Genet , vol.20 , pp. 5012-5023
    • Amos, C.I.1    Wang, L.E.2    Lee, J.E.3    Gershenwald, J.E.4    Chen, W.V.5    Fang, S.6
  • 16
    • 23644448602 scopus 로고    scopus 로고
    • Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma
    • Jannot AS, Meziani R, Bertrand G, Gérard B, Descamps V, Archimbaud A, et al. Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma. Eur J Hum Genet 2005; 13:913-920.
    • (2005) Eur J Hum Genet , vol.13 , pp. 913-920
    • Jannot, A.S.1    Meziani, R.2    Bertrand, G.3    Gérard, B.4    Descamps, V.5    Archimbaud, A.6
  • 17
    • 77955068269 scopus 로고    scopus 로고
    • IRF4 variants have age-specific effects on nevus count and predispose to melanoma
    • Duffy DL, Iles MM, Glass D, Zhu G, Barrett JH, Höiom V, et al. IRF4 variants have age-specific effects on nevus count and predispose to melanoma. Am J Hum Genet 2010; 87:6-16.
    • (2010) Am J Hum Genet , vol.87 , pp. 6-16
    • Duffy, D.L.1    Iles, M.M.2    Glass, D.3    Zhu, G.4    Barrett, J.H.5    Höiom, V.6
  • 18
    • 75549084094 scopus 로고    scopus 로고
    • Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma
    • Duffy DL, Zhao ZZ, Sturm RA, Hayward NK, Martin NG, Montgomery GW. Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma. J Invest Dermatol 2010; 130:520-528.
    • (2010) J Invest Dermatol , vol.130 , pp. 520-528
    • Duffy, D.L.1    Zhao, Z.Z.2    Sturm, R.A.3    Hayward, N.K.4    Martin, N.G.5    Montgomery, G.W.6
  • 19
    • 84873495253 scopus 로고    scopus 로고
    • Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study
    • Stefanaki I, Panagiotou OA, Kodela E, Gogas H, Kypreou KP, Chatzinasiou F, et al. Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study. PLoS One 2013; 8:e55712.
    • (2013) PLoS One , vol.8
    • Stefanaki, I.1    Panagiotou, O.A.2    Kodela, E.3    Gogas, H.4    Kypreou, K.P.5    Chatzinasiou, F.6
  • 24
    • 84856072305 scopus 로고    scopus 로고
    • The first genome-wide view of vitamin D receptor locations and their mechanistic implications
    • Carlberg C, Seuter S, Heikkinen S. The first genome-wide view of vitamin D receptor locations and their mechanistic implications. Anticancer Res 2012; 32:271-282.
    • (2012) Anticancer Res , vol.32 , pp. 271-282
    • Carlberg, C.1    Seuter, S.2    Heikkinen, S.3
  • 25
    • 17544392528 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma
    • Hutchinson PE, Osborne JE, Lear JT, Smith AG, Bowers PW, Morris PN, et al. Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma. Clin Cancer Res 2000; 6:498-504.
    • (2000) Clin Cancer Res , vol.6 , pp. 498-504
    • Hutchinson, P.E.1    Osborne, J.E.2    Lear, J.T.3    Smith, A.G.4    Bowers, P.W.5    Morris, P.N.6
  • 26
    • 4344663455 scopus 로고    scopus 로고
    • A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibility and prognosis in malignant melanoma
    • Halsall JA, Osborne JE, Potter L, Pringle JH, Hutchinson PE. A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibility and prognosis in malignant melanoma. Br J Cancer 2004; 91:765-770.
    • (2004) Br J Cancer , vol.91 , pp. 765-770
    • Halsall, J.A.1    Osborne, J.E.2    Potter, L.3    Pringle, J.H.4    Hutchinson, P.E.5
  • 27
  • 28
    • 80054026938 scopus 로고    scopus 로고
    • Vitamin D receptor (VDR) polymorphisms and skin cancer: A systematic review
    • Denzer N, Vogt T, Reichrath J. Vitamin D receptor (VDR) polymorphisms and skin cancer: a systematic review. Dermatoendocrinol 2011; 3:205-210.
    • (2011) Dermatoendocrinol , vol.3 , pp. 205-210
    • Denzer, N.1    Vogt, T.2    Reichrath, J.3
  • 29
    • 83655201530 scopus 로고    scopus 로고
    • GEM Study Group. Vitamin D receptor polymorphisms in patients with cutaneous melanoma
    • Orlow I, Roy P, Reiner AS, Yoo S, Patel H, Paine S, et al. GEM Study Group. Vitamin D receptor polymorphisms in patients with cutaneous melanoma. Int J Cancer 2012; 130:405-418.
    • (2012) Int J Cancer , vol.130 , pp. 405-418
    • Orlow, I.1    Roy, P.2    Reiner, A.S.3    Yoo, S.4    Patel, H.5    Paine, S.6
  • 30
    • 0022611831 scopus 로고
    • Ultraviolet-induced pigmentary changes: Benefits and hazards
    • Fitzpatrick TB. Ultraviolet-induced pigmentary changes: benefits and hazards. Curr Probl Dermatol 1986; 15:25-38.
    • (1986) Curr Probl Dermatol , vol.15 , pp. 25-38
    • Fitzpatrick, T.B.1
  • 32
    • 84897032014 scopus 로고    scopus 로고
    • The common occurrence of epistasis in the determination of human pigmentation and its impact on DNA-based pigmentation phenotype prediction
    • Popiech E, Wojas-Pelc A, Walsh S, Liu F, Maeda H, Ishikawa T, et al. The common occurrence of epistasis in the determination of human pigmentation and its impact on DNA-based pigmentation phenotype prediction. Forensic Sci Int Genet 2014; 11C:64-72.
    • (2014) Forensic Sci Int Genet , vol.11 C , pp. 64-72
    • Popiech, E.1    Wojas-Pelc, A.2    Walsh, S.3    Liu, F.4    Maeda, H.5    Ishikawa, T.6
  • 33
    • 79951807758 scopus 로고    scopus 로고
    • The unfavorable effect of the A allele of the vitamin D receptor promoter polymorphism A-1012G has different mechanisms related to susceptibility and outcome of malignant melanoma
    • Hallsal JA, Osborne JE, Epstein MP, Pringle JH, Peter E, Hutchinson PE. The unfavorable effect of the A allele of the vitamin D receptor promoter polymorphism A-1012G has different mechanisms related to susceptibility and outcome of malignant melanoma. Dermatoendocrinol 2009; 1:54-57.
    • (2009) Dermatoendocrinol , vol.1 , pp. 54-57
    • Hallsal, J.A.1    Osborne, J.E.2    Epstein, M.P.3    Pringle, J.H.4    Peter, E.5    Hutchinson, P.E.6
  • 34
    • 4344675303 scopus 로고    scopus 로고
    • Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene
    • Nejentsev S, Godfrey L, Snook H, Rance H, Nutland S, Walker NM, et al. Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene. Hum Mol Genet 2004; 13:1633-1639.
    • (2004) Hum Mol Genet , vol.13 , pp. 1633-1639
    • Nejentsev, S.1    Godfrey, L.2    Snook, H.3    Rance, H.4    Nutland, S.5    Walker, N.M.6
  • 35
    • 33748754035 scopus 로고    scopus 로고
    • Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies
    • Dempfle A, Wudy SA, Saar K, Hagemann S, Friedel S, Scherag A, et al. Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies. Hum Mol Genet 2006; 15:2772-2783.
    • (2006) Hum Mol Genet , vol.15 , pp. 2772-2783
    • Dempfle, A.1    Wudy, S.A.2    Saar, K.3    Hagemann, S.4    Friedel, S.5    Scherag, A.6
  • 36
    • 60549085065 scopus 로고    scopus 로고
    • Interactions between HERC2 OCA2 and MC1R may influence human pigmentation phenotype
    • Branicki W, Brudnik U, Wojas-Pelc A. Interactions between HERC2, OCA2 and MC1R may influence human pigmentation phenotype. Ann Hum Genet 2009; 73:160-170.
    • (2009) Ann Hum Genet , vol.73 , pp. 160-170
    • Branicki, W.1    Brudnik, U.2    Wojas-Pelc, A.3
  • 37
    • 0022646577 scopus 로고
    • Effects of melanininduced free radicals on the isolated rat peritoneal mast cells
    • Ranadive NS, Shirwadkar S, Persad S, Menon IA. Effects of melanininduced free radicals on the isolated rat peritoneal mast cells. J Invest Dermatol 1986; 86:303-307.
    • (1986) J Invest Dermatol , vol.86 , pp. 303-307
    • Ranadive, N.S.1    Shirwadkar, S.2    Persad, S.3    Menon, I.A.4
  • 38
    • 84869084595 scopus 로고    scopus 로고
    • An ultravioletradiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background
    • Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, et al. An ultravioletradiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature 2012; 491:449-453.
    • (2012) Nature , vol.491 , pp. 449-453
    • Mitra, D.1    Luo, X.2    Morgan, A.3    Wang, J.4    Hoang, M.P.5    Lo, J.6
  • 40
    • 17644432720 scopus 로고    scopus 로고
    • Melanocortin 1 receptor (MC1R) gene variants may increase the risk of melanoma in France independently of clinical risk factors and UV exposure
    • Matichard E, Verpillat P, Meziani R, Gérard B, Descamps V, Legroux E, et al. Melanocortin 1 receptor (MC1R) gene variants may increase the risk of melanoma in France independently of clinical risk factors and UV exposure. J Med Genet 2004; 41:e13.
    • (2004) J Med Genet , vol.41
    • Matichard, E.1    Verpillat, P.2    Meziani, R.3    Gérard, B.4    Descamps, V.5    Legroux, E.6
  • 41
    • 21244446712 scopus 로고    scopus 로고
    • MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population
    • Landi MT, Kanetsky PA, Tsang S, Gold B, Munroe D, Rebbeck T, et al. MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population. J Natl Cancer Inst 2005; 97:998-1007.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 998-1007
    • Landi, M.T.1    Kanetsky, P.A.2    Tsang, S.3    Gold, B.4    Munroe, D.5    Rebbeck, T.6
  • 42
    • 33750626267 scopus 로고    scopus 로고
    • MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
    • Dbniak T, Scott R, Masojc B, Serrano-Fernández P, Huzarski T, Byrski T, et al. MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk. Int J Cancer 2006; 119:2597-2602.
    • (2006) Int J Cancer , vol.119 , pp. 2597-2602
    • Dbniak, T.1    Scott, R.2    Masojc, B.3    Serrano-Fernández, P.4    Huzarski, T.5    Byrski, T.6
  • 44
    • 31544458930 scopus 로고    scopus 로고
    • Re: MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population
    • Fargnoli MC, Spica T, Sera F, Pellacani G, Chiarugi A, Seidenari S, et al. Re: MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population. J Natl Cancer Inst 2006; 98:144-145.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 144-145
    • Fargnoli, M.C.1    Spica, T.2    Sera, F.3    Pellacani, G.4    Chiarugi, A.5    Seidenari, S.6
  • 46
    • 33845496518 scopus 로고    scopus 로고
    • Variations of the melanocortin-1 receptor and the glutathione-S transferase T1 and M1 genes in cutaneous malignant melanoma
    • Mössner R, Anders N, König IR, Krüger U, Schmidt D, Berking C, et al. Variations of the melanocortin-1 receptor and the glutathione-S transferase T1 and M1 genes in cutaneous malignant melanoma. Arch Dermatol Res 2007; 298:371-379.
    • (2007) Arch Dermatol Res , vol.298 , pp. 371-379
    • Mössner, R.1    Anders, N.2    König, I.R.3    Krüger, U.4    Schmidt, D.5    Berking, C.6
  • 47
    • 34548135234 scopus 로고    scopus 로고
    • MC1R: Three novel variants identified in a malignant melanoma association study in the Spanish population
    • Fernandez L, Milne R, Bravo J, Lopez J, Avilés J, Longo M, et al. MC1R: three novel variants identified in a malignant melanoma association study in the Spanish population. Carcinogenesis 2007; 28:1659-1664.
    • (2007) Carcinogenesis , vol.28 , pp. 1659-1664
    • Fernandez, L.1    Milne, R.2    Bravo, J.3    Lopez, J.4    Avilés, J.5    Longo, M.6
  • 49
    • 65249108089 scopus 로고    scopus 로고
    • Contribution of genetic factors for melanoma susceptibility in sporadic US melanoma patients
    • Council ML, Gardner JM, Helms C, Liu Y, Cornelius LA, Bowcock AM. Contribution of genetic factors for melanoma susceptibility in sporadic US melanoma patients. Exp Dermatol 2009; 18:485-487.
    • (2009) Exp Dermatol , vol.18 , pp. 485-487
    • Council, M.L.1    Gardner, J.M.2    Helms, C.3    Liu, Y.4    Cornelius, L.A.5    Bowcock, A.M.6
  • 52
  • 54
    • 0028786945 scopus 로고
    • Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
    • Valverde P, Healy E, Jackson I, Rees JL, Thody AJ. Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat Genet 1995; 11:328-330.
    • (1995) Nat Genet , vol.11 , pp. 328-330
    • Valverde, P.1    Healy, E.2    Jackson, I.3    Rees, J.L.4    Thody, A.J.5
  • 55
    • 4644237315 scopus 로고    scopus 로고
    • Melanin pigmentation in mammalian skin and its hormonal regulation
    • Slominski A, Tobin DJ, Shibahara S, Wortsman J. Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev 2004; 84:1155-1228.
    • (2004) Physiol Rev , vol.84 , pp. 1155-1228
    • Slominski, A.1    Tobin, D.J.2    Shibahara, S.3    Wortsman, J.4
  • 57
    • 0035068231 scopus 로고    scopus 로고
    • Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair
    • Leiden Skin Cancer Study Team
    • Bastiaens MT, ter Huurne JA, Kielich C, Gruis NA, Westendorp RG, Vermeer BJ, Bavinck JN. Leiden Skin Cancer Study Team. Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair. Am J Hum Genet 2001; 68:884-894.
    • (2001) Am J Hum Genet , vol.68 , pp. 884-894
    • Bastiaens, M.T.1    Ter Huurne, J.A.2    Kielich, C.3    Gruis, N.A.4    Westendorp, R.G.5    Vermeer, B.J.6    Bavinck, J.N.7
  • 58
    • 40349087179 scopus 로고    scopus 로고
    • MC1R variants associated susceptibility to basal cell carcinoma of skin: Interaction with host factors and XRCC3 polymorphism
    • Scherer D, Bermejo JL, Rudnai P, Gurzau E, Koppova K, Hemminki K, Kumar R. MC1R variants associated susceptibility to basal cell carcinoma of skin: interaction with host factors and XRCC3 polymorphism. Int J Cancer 2008; 122:1787-1793.
    • (2008) Int J Cancer , vol.122 , pp. 1787-1793
    • Scherer, D.1    Bermejo, J.L.2    Rudnai, P.3    Gurzau, E.4    Koppova, K.5    Hemminki, K.6    Kumar, R.7
  • 59
    • 84864414684 scopus 로고    scopus 로고
    • Potential association of single nucleotide polymorphisms in pigmentation genes with the development of basal cell carcinoma
    • Kosiniak-Kamysz A, Popiech E, Wojas-Pelc A, Marciska M, Branicki W. Potential association of single nucleotide polymorphisms in pigmentation genes with the development of basal cell carcinoma. J Dermatol 2012; 39:693-698.
    • (2012) J Dermatol , vol.39 , pp. 693-698
    • Kosiniak-Kamysz, A.1    Popiech, E.2    Wojas-Pelc, A.3    Marciska, M.4    Branicki, W.5
  • 60
    • 68149179663 scopus 로고    scopus 로고
    • Genome-wide association study identifies three loci associated with melanoma risk
    • Bishop DT, Demenais F, Iles MM, Harland M, Taylor JC, Corda E, et al. Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet 2009; 41:920-925.
    • (2009) Nat Genet , vol.41 , pp. 920-925
    • Bishop, D.T.1    Demenais, F.2    Iles, M.M.3    Harland, M.4    Taylor, J.C.5    Corda, E.6
  • 61
    • 79955772617 scopus 로고    scopus 로고
    • A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in theSLC45A2 gene
    • Ibarrola-Villava M, Fernandez LP, Alonso S, Boyano MD, Pena-Chilet M, Pita G, et al. A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in theSLC45A2 gene. PloS One 2011; 6:e19271.
    • (2011) PloS One , vol.6
    • Ibarrola-Villava, M.1    Fernandez, L.P.2    Alonso, S.3    Boyano, M.D.4    Pena-Chilet, M.5    Pita, G.6
  • 63
    • 14944367557 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation
    • Graf J, Hodgson R, van Daal A. Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation. Hum Mutat 2005; 25:278-284.
    • (2005) Hum Mutat , vol.25 , pp. 278-284
    • Graf, J.1    Hodgson, R.2    Van Daal, A.3
  • 64
    • 57349185942 scopus 로고    scopus 로고
    • Association of the SLC45A2 gene with physiological human hair colour variation
    • Branicki W, Brudnik U, Draus-Barini J, Kupiec T, Wojas-Pelc A. Association of the SLC45A2 gene with physiological human hair colour variation. J Hum Genet 2008; 53:966-971.
    • (2008) J Hum Genet , vol.53 , pp. 966-971
    • Branicki, W.1    Brudnik, U.2    Draus-Barini, J.3    Kupiec, T.4    Wojas-Pelc, A.5
  • 66
    • 67650073375 scopus 로고    scopus 로고
    • Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians
    • Nan H, Kraft P, Hunter DJ, Han J. Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians. Int J Cancer 2009; 125:909-917.
    • (2009) Int J Cancer , vol.125 , pp. 909-917
    • Nan, H.1    Kraft, P.2    Hunter, D.J.3    Han, J.4
  • 69
    • 84884411959 scopus 로고    scopus 로고
    • Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanoma
    • Broyna AA, Jówicki W, Carlson JA, Slominski AT. Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanoma. Hum Pathol 2013; 44:2071-2074.
    • (2013) Hum Pathol , vol.44 , pp. 2071-2074
    • Broyna, A.A.1    Jówicki, W.2    Carlson, J.A.3    Slominski, A.T.4
  • 70
    • 49749108996 scopus 로고    scopus 로고
    • Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy
    • Brozyna AA, VanMiddlesworth L, Slominski AT. Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy. Int J Cancer 2008; 123:1448-1456.
    • (2008) Int J Cancer , vol.123 , pp. 1448-1456
    • Brozyna, A.A.1    Vanmiddlesworth, L.2    Slominski, A.T.3
  • 71
    • 60549090637 scopus 로고    scopus 로고
    • Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells
    • Slominski A, Zbytek B, Slominski R. Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells. Int J Cancer 2009; 124:1470-1477.
    • (2009) Int J Cancer , vol.124 , pp. 1470-1477
    • Slominski, A.1    Zbytek, B.2    Slominski, R.3
  • 72
    • 83955164260 scopus 로고    scopus 로고
    • L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions
    • Slominski A, Zmijewski MA, Pawelek J. L-tyrosine and L- dihydroxyphenylalanine as hormone-like regulators of melanocyte functions. Pigment Cell Melanoma Res 2012; 25:14-27.
    • (2012) Pigment Cell Melanoma Res , vol.25 , pp. 14-27
    • Slominski, A.1    Zmijewski, M.A.2    Pawelek, J.3
  • 74
    • 0019462379 scopus 로고
    • 1,25-dihydroxyvitamin D3 and malignant melanoma: The presence of receptors and inhibition of cell growth in culture
    • Colston K, Colston MJ, Feldman D. 1,25-dihydroxyvitamin D3 and malignant melanoma: the presence of receptors and inhibition of cell growth in culture. Endocrinology 1981; 108:1083-1086.
    • (1981) Endocrinology , vol.108 , pp. 1083-1086
    • Colston, K.1    Colston, M.J.2    Feldman, D.3
  • 75
    • 0030043439 scopus 로고    scopus 로고
    • Vitamin D receptor and growth inhibition by 1,25-dihydroxyvitamin D3 in human malignant melanoma cell lines
    • Evans SR, Houghton AM, Schumaker L, Brenner RV, Buras RR, Davoodi F, et al. Vitamin D receptor and growth inhibition by 1,25-dihydroxyvitamin D3 in human malignant melanoma cell lines. J Surg Res 1996; 61:127-133.
    • (1996) J Surg Res , vol.61 , pp. 127-133
    • Evans, S.R.1    Houghton, A.M.2    Schumaker, L.3    Brenner, R.V.4    Buras, R.R.5    Davoodi, F.6
  • 76
    • 84906790378 scopus 로고    scopus 로고
    • The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions
    • S0960-076000205-7. doi: 10.1016/j.jsbmb.2013.10.012. [ Epub ahead of print]
    • Slominski AT, Kim TK, Li W, Yid AK, Postlethwaite A, Tuckey RC. The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions. J Steroid Biochem Mol Biol 2013 S0960-0760:00205-7. doi: 10.1016/j.jsbmb.2013.10.012. [Epub ahead of print].
    • (2013) J Steroid Biochem Mol Biol
    • Slominski, A.T.1    Kim, T.K.2    Li, W.3    Yid, A.K.4    Postlethwaite, A.5    Tuckey, R.C.6
  • 78
    • 68549118801 scopus 로고    scopus 로고
    • The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: A review of the literature
    • Köstner K, Denzer N, Müller CS, Klein R, Tilgen W, Reichrath J. The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature. Anticancer Res 2009; 29:3511-3536.
    • (2009) Anticancer Res , vol.29 , pp. 3511-3536
    • Köstner, K.1    Denzer, N.2    Müller, C.S.3    Klein, R.4    Tilgen, W.5    Reichrath, J.6
  • 79
    • 70450202460 scopus 로고    scopus 로고
    • Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data
    • Randerson-Moor JA, Taylor JC, Elliott F, Chang YM, Beswick S, Kukalizch K, et al. Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data. Eur J Cancer 2009; 45:3271-3281.
    • (2009) Eur J Cancer , vol.45 , pp. 3271-3281
    • Randerson-Moor, J.A.1    Taylor, J.C.2    Elliott, F.3    Chang, Y.M.4    Beswick, S.5    Kukalizch, K.6
  • 80
    • 60549101069 scopus 로고    scopus 로고
    • Genetic analysis of the vitamin D receptor gene in two epithelial cancers: Melanoma and breast cancer case-control studies
    • Barroso E, Fernandez LP, Milne RL, Pita G, Sendagorta E, Floristan U, et al. Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies. BMC Cancer 2008; 8:385.
    • (2008) BMC Cancer , vol.8 , pp. 385
    • Barroso, E.1    Fernandez, L.P.2    Milne, R.L.3    Pita, G.4    Sendagorta, E.5    Floristan, U.6
  • 81
    • 55549097452 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms and the risk of cutaneous melanoma: A systematic review and meta-analysis
    • Mocellin S, Nitti D. Vitamin D receptor polymorphisms and the risk of cutaneous melanoma: a systematic review and meta-analysis. Cancer 2008; 113:2398-2407.
    • (2008) Cancer , vol.113 , pp. 2398-2407
    • Mocellin, S.1    Nitti, D.2
  • 82
    • 33847288858 scopus 로고    scopus 로고
    • Polymorphisms in the MTHFR and VDR genes and skin cancer risk
    • Han J, Colditz GA, Hunter DJ. Polymorphisms in the MTHFR and VDR genes and skin cancer risk. Carcinogenesis 2007; 28:390-397.
    • (2007) Carcinogenesis , vol.28 , pp. 390-397
    • Han, J.1    Colditz, G.A.2    Hunter, D.J.3
  • 83
    • 27944445478 scopus 로고    scopus 로고
    • Two single-nucleotide polymorphisms in the human vitamin D receptor promoter change protein-DNA complex formation and are associated with height and vitamin D status in adolescent girls
    • d'Alésio A, Garabédian M, Sabatier JP, Guaydier- Souquières G, Marcelli C, Lemaçon A, et al. Two single-nucleotide polymorphisms in the human vitamin D receptor promoter change protein-DNA complex formation and are associated with height and vitamin D status in adolescent girls. Hum Mol Genet 2005; 14:3539-3548.
    • (2005) Hum Mol Genet , vol.14 , pp. 3539-3548
    • D'Alésio, A.1    Garabédian, M.2    Sabatier, J.P.3    Guaydier-Souquières, G.4    Marcelli, C.5    Lemaçon, A.6
  • 85
    • 84861966707 scopus 로고    scopus 로고
    • The-4817GA (rs2238136) variant of the vitamin D receptor gene: A probable risk factor for colorectal cancer
    • Mahmoudi T, Arkani M, Karimi K, Safaei A, Rostami F, Arbabi E, et al. The-4817GA (rs2238136) variant of the vitamin D receptor gene: a probable risk factor for colorectal cancer. Mol Biol Rep 2012; 39:5277-5282.
    • (2012) Mol Biol Rep , vol.39 , pp. 5277-5282
    • Mahmoudi, T.1    Arkani, M.2    Karimi, K.3    Safaei, A.4    Rostami, F.5    Arbabi, E.6
  • 86
    • 78649693137 scopus 로고    scopus 로고
    • Evolutionary perspective in skin color, vitamin D and its receptor
    • Hochberg Z, Templeton AR. Evolutionary perspective in skin color, vitamin D and its receptor. Hormones (Athens) 2010; 9:307-311.
    • (2010) Hormones (Athens , vol.9 , pp. 307-311
    • Hochberg, Z.1    Templeton, A.R.2
  • 87
    • 40749158014 scopus 로고    scopus 로고
    • A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color
    • Sturm RA, Duffy DL, Zhao ZZ, Leite FP, Stark MS, Hayward NK, et al. A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color. Am J Hum Genet 2008; 82:424-431.
    • (2008) Am J Hum Genet , vol.82 , pp. 424-431
    • Sturm, R.A.1    Duffy, D.L.2    Zhao, Z.Z.3    Leite, F.P.4    Stark, M.S.5    Hayward, N.K.6
  • 88
  • 89
    • 0345411335 scopus 로고    scopus 로고
    • The ubiquitous nature of epistasis in determining susceptibility to common human diseases
    • Moore JH. The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered 2003; 56:73-82.
    • (2003) Hum Hered , vol.56 , pp. 73-82
    • Moore, J.H.1
  • 90
    • 3442894519 scopus 로고    scopus 로고
    • Epistasis: Too often neglected in complex trait studies?
    • Carlborg O, Haley CS. Epistasis: too often neglected in complex trait studies? Nat Rev Genet 2004; 5:618-625.
    • (2004) Nat Rev Genet , vol.5 , pp. 618-625
    • Carlborg, O.1    Haley, C.S.2
  • 92
    • 77953194221 scopus 로고    scopus 로고
    • Digital quantification of human eye color highlights genetic association of three new loci
    • Liu F, Wollstein A, Hysi PG, Ankra-Badu GA, Spector TD, Park D, et al. Digital quantification of human eye color highlights genetic association of three new loci. PLoS Genet 2010; 6:e1000934.
    • (2010) PLoS Genet , vol.6
    • Liu, F.1    Wollstein, A.2    Hysi, P.G.3    Ankra-Badu, G.A.4    Spector, T.D.5    Park, D.6


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