Poly(lactide-co-glycolide)/fibrin gel construct as a 3D model to evaluate gene therapy of cartilage in vivo

Molecular Pharmaceutics

Volumn 11, Issue 7, 2014, Pages 2062-2070

  Li, Bo ^a   Li, Feifei ^a   Ma, Lie ^a   Yang, Junzhou ^a   Wang, Chunfen ^a   Wang, Dongan ^b   Gao, Changyou ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b Nanyang Technological University   (Singapore)

Author keywords

cartilage repair; fibrin gel; gene therapy; MSCs; PLGA

Indexed keywords

AGGRECAN; BACTERIAL DNA; COLLAGEN TYPE 1; COLLAGEN TYPE 10; COLLAGEN TYPE 2; FIBRIN; FIBRIN GEL; GLYCOSAMINOGLYCAN; LIPOFECTAMINE; LIPOPLEX; POLYGLACTIN; TISSUE SCAFFOLD; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; GEL; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHROPATHY; ARTICLE; ARTICULAR CARTILAGE; BONE REGENERATION; CELL CULTURE; CELL DENSITY; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; IN VIVO STUDY; MALE; MESENCHYMAL STEM CELL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHASE SEPARATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TISSUE ENGINEERING; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ANIMAL; BONE MARROW CELL; CARTILAGE; CHEMISTRY; DRUG EFFECTS; GEL; GENE THERAPY; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; PROCEDURES; RABBIT; REGENERATION; TISSUE SCAFFOLD;

ANIMALS; BONE MARROW CELLS; CARTILAGE; FEMALE; FIBRIN; GELS; GENETIC THERAPY; GLYCOSAMINOGLYCANS; MALE; MESENCHYMAL STROMAL CELLS; POLYGLACTIN 910; RABBITS; REGENERATION; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84904018020     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp5000136     Document Type: Article

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