Tubulin polymerization disrupts cardiac -adrenergic regulation of late INa

Cardiovascular Research

Volumn 103, Issue 1, 2014, Pages 168-177

  Dybkova, Nataliya ^a,b   Wagner, Stefan ^a,b,e   Backs, Johannes ^b,c   Hund, Thomas J ^d   Mohler, Peter J ^d   Sowa, Thomas ^a,b   Nikolaev, Viacheslav O ^a,b   Maier, Lars S ^e  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d OHIO STATE UNIVERSITY   (United States)

^e UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Adrenergic stimulation; Calcium calmodulin dependent protein kinase II; Microtubules; Paclitaxel; Sodium channels

Indexed keywords

ANTIPORTER; BETA ARRESTIN; BETA ARRESTIN 2; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP; ISOPRENALINE; PACLITAXEL; SMALL INTERFERING RNA; SODIUM CHANNEL; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CAMK2D PROTEIN, MOUSE; RETINA S ANTIGEN; TUBULIN; TUBULIN MODULATOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; SODIUM CHANNEL NAV1.5;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; ELECTRIC POTENTIAL; HEART FAILURE; HEK293 CELL LINE; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SODIUM CURRENT; STEADY STATE; WESTERN BLOTTING; WILD TYPE; ANIMAL; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; ENZYME ACTIVATION; FEMALE; GENETICS; HEART MUSCLE CELL; KNOCKOUT MOUSE; MALE; METABOLISM; MICROTUBULE; PHOSPHORYLATION; POLYMERIZATION; PROTEIN MULTIMERIZATION; ANIMAL TISSUE; CHANNEL GATING; EMBRYO; GENE SILENCING; PROTEIN EXPRESSION; SODIUM CONDUCTANCE;

ADRENERGIC BETA-AGONISTS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARRESTINS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; ENZYME ACTIVATION; FEMALE; HEK293 CELLS; HUMANS; ISOPROTERENOL; MALE; MICE; MICE, KNOCKOUT; MICROTUBULES; MYOCYTES, CARDIAC; PACLITAXEL; PHOSPHORYLATION; POLYMERIZATION; PROTEIN MULTIMERIZATION; RECEPTORS, ADRENERGIC, BETA; SODIUM CHANNELS; TUBULIN; TUBULIN MODULATORS;

EID: 84903999780     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvu120     Document Type: Article

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