A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

DMM Disease Models and Mechanisms

Volumn 7, Issue 7, 2014, Pages 907-913

  Burger, Alexa ^a,b,e   Vasilyev, Aleksandr ^a,c   Tomar, Ritu ^a   Selig, Martin K ^a   Nielsen, G Petur ^a   Peterson, Randall T ^a,d   Drummond, Iain A ^a   Haber, Daniel A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NEW YORK INSTITUTE OF TECHNOLOGY   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cancer; Chordoma; Drug treatment; HRASV12; Rapamycin; Zebrafish

Indexed keywords

RAPAMYCIN; HRAS PROTEIN, HUMAN; PROTEIN P21;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CHORDOMA; CONTROLLED STUDY; DISEASE MODEL; ELECTRON MICROSCOPY; HIGH THROUGHPUT SCREENING; IMMUNOHISTOCHEMISTRY; NONHUMAN; NOTOCHORD; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENE; ZEBRA FISH; ANIMAL; ANTIBODY SPECIFICITY; DISEASE COURSE; DRUG EFFECTS; EMBRYOLOGY; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY; SURVIVAL; TRANSGENIC ANIMAL; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARCINOGENESIS; CELL LINE, TUMOR; CHORDOMA; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MUTATION; NOTOCHORD; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS P21(RAS); SIROLIMUS; SURVIVAL ANALYSIS; ZEBRAFISH;

EID: 84903934824     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.013128     Document Type: Article

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