Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish

PLoS ONE

Volumn 5, Issue 12, 2010, Pages 1-11

  Santoriello, Cristina ^a   Gennaro, Elisa ^a   Anelli, Viviana ^a   Distel, Martin ^b   Kelly, Amanda ^c   Köster, Reinhard W ^b   Hurlstone, Adam ^c   Mione, Marina ^a  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BROXURIDINE; PROTEIN P53; TRANSCRIPTION FACTOR GAL4; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P21; STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL STRAIN; ELECTRON MICROSCOPY; GENE EXPRESSION; GENE MUTATION; HISTOLOGY; HYPERPIGMENTATION; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MELANOCYTE; MELANOMA; NICK END LABELING; NONHUMAN; ONCOGENE H RAS; ONSET AGE; PHENOTYPE; RNA EXTRACTION; TRANSGENICS; TUMOR CELL; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; ZEBRA FISH; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; DISEASE COURSE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROMOTER REGION; SKIN TUMOR; TRANSGENE; TRANSGENIC ANIMAL;

ANIMALIA; DANIO RERIO;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; MELANOCYTES; MELANOMA; MODELS, GENETIC; PHENOTYPE; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-KIT; PROTO-ONCOGENE PROTEINS P21(RAS); PTEN PHOSPHOHYDROLASE; SKIN NEOPLASMS; TRANSGENES; ZEBRAFISH;

EID: 78650748163     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015170     Document Type: Article

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