-
1
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon E, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.1
Vogelstein, B.2
-
2
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt M, Benett W, Hollstein M, Harris C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 1994;54:4855-4878.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.1
Benett, W.2
Hollstein, M.3
Harris, C.4
-
3
-
-
0029849620
-
Cancer cell cycles
-
Sherr C. Cancer cell cycles. Science. 1996;274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.1
-
4
-
-
0028074536
-
Alterations in the p53 and MDM-2 genes are infrequent in clinically localized, stage B prostate adenocarcinomas
-
Ittmann M, Wieczorek R, Heller P, Dave A, Provet J, Krolewski J. Alterations in the p53 and MDM-2 genes are infrequent in clinically localized, stage B prostate adenocarcinomas. Am J Pathol. 1994;145:287-293.
-
(1994)
Am J Pathol
, vol.145
, pp. 287-293
-
-
Ittmann, M.1
Wieczorek, R.2
Heller, P.3
Dave, A.4
Provet, J.5
Krolewski, J.6
-
5
-
-
0027229136
-
Functional interaction of the retinoblastoma protein with mammalian D-type cyclins
-
Ewen M, Sluss H, Sherr C, Matsushime H, Kato J, Livingston D. Functional interaction of the retinoblastoma protein with mammalian D-type cyclins. Cell. 1993;73:487-497.
-
(1993)
Cell
, vol.73
, pp. 487-497
-
-
Ewen, M.1
Sluss, H.2
Sherr, C.3
Matsushime, H.4
Kato, J.5
Livingston, D.6
-
6
-
-
0029119740
-
Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin dependent kinase inhibitors (CKIs)
-
Grana X, Reddy E. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin dependent kinase inhibitors (CKIs). Oncogene. 1995;11:211-219.
-
(1995)
Oncogene
, vol.11
, pp. 211-219
-
-
Grana, X.1
Reddy, E.2
-
7
-
-
0142212234
-
Skull base and non-skull base chordomas: Clinicopathologic and immunohistochemical study with special reference to nuclear pleomorphism and proliferative ability
-
Naka T, Boltze C, Samii S, et al. Skull base and non-skull base chordomas: clinicopathologic and immunohistochemical study with special reference to nuclear pleomorphism and proliferative ability. Cancer. 2003;98:1934-1941.
-
(2003)
Cancer
, vol.98
, pp. 1934-1941
-
-
Naka, T.1
Boltze, C.2
Samii, S.3
-
8
-
-
0032521376
-
Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53
-
Cote R, Dunn M, Chatterjee S, et al. Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53. Cancer Res. 1998;58: 1090-1094.
-
(1998)
Cancer Res
, vol.58
, pp. 1090-1094
-
-
Cote, R.1
Dunn, M.2
Chatterjee, S.3
-
9
-
-
15444355382
-
Expression of p53, p21, mdm2, Rb, bax and Ki67 proteins in lymphomas of the mucosa-associated lymphoid (MALT) tissue
-
Stefanaki K, Tzardi M, Kouvidou C, et al. Expression of p53, p21, mdm2, Rb, bax and Ki67 proteins in lymphomas of the mucosa-associated lymphoid (MALT) tissue. Anticancer Res. 1998;18:2403-2408.
-
(1998)
Anticancer Res
, vol.18
, pp. 2403-2408
-
-
Stefanaki, K.1
Tzardi, M.2
Kouvidou, C.3
-
10
-
-
0030934688
-
Colonic retinoblastoma protein and proliferation in cancer and non-cancer patients
-
Kohn GJ, Schwartz HJ, Buebner BH, Wong AJ, Lawson MJ. Colonic retinoblastoma protein and proliferation in cancer and non-cancer patients. J Gastroenterol Hepatol. 1997;12: 198-203.
-
(1997)
J Gastroenterol Hepatol
, vol.12
, pp. 198-203
-
-
Kohn, G.J.1
Schwartz, H.J.2
Buebner, B.H.3
Wong, A.J.4
Lawson, M.J.5
-
11
-
-
0032898402
-
Altered patterns of retinoblastoma gene product expression in benign, premalignant and malignant epithelium of the larynx: An immunohistochemical study including correlation with p53, bcl-2 and proliferating indices
-
Ioachim E, Assimakopoulos D, Agnantis N, Peschos D, Zissi A, Skevas A. Altered patterns of retinoblastoma gene product expression in benign, premalignant and malignant epithelium of the larynx: an immunohistochemical study including correlation with p53, bcl-2 and proliferating indices. Anticancer Res. 1999;19:541-546.
-
(1999)
Anticancer Res
, vol.19
, pp. 541-546
-
-
Ioachim, E.1
Assimakopoulos, D.2
Agnantis, N.3
Peschos, D.4
Zissi, A.5
Skevas, A.6
-
12
-
-
0031443974
-
Improved detection of p53 mutations in soft tissue tumors using new gel composition for automated non radioactive analysis of single-strand conformation polymorphism
-
Schneider-Stock R, Haeckel C, Radig K, Pein C, Roessner A. Improved detection of p53 mutations in soft tissue tumors using new gel composition for automated non radioactive analysis of single-strand conformation polymorphism. Electrophoresis. 1997;18:2849-2851.
-
(1997)
Electrophoresis
, vol.18
, pp. 2849-2851
-
-
Schneider-Stock, R.1
Haeckel, C.2
Radig, K.3
Pein, C.4
Roessner, A.5
-
13
-
-
84988101333
-
Silver staining of DNA in polyacrylamide gels: Linearity and effect of fragment size
-
Goldmann D, Merril C. Silver staining of DNA in polyacrylamide gels: linearity and effect of fragment size. Electrophoresis. 1982;3:24-26.
-
(1982)
Electrophoresis
, vol.3
, pp. 24-26
-
-
Goldmann, D.1
Merril, C.2
-
14
-
-
0034194216
-
Prognostic factors in chordoma of the sacrum and mobile spine: A study of 39 patients
-
Bergh P, Kindblom L, Gunterberg B, Remotti F, Ryd W, Meis-Kindblom J. Prognostic factors in chordoma of the sacrum and mobile spine: a study of 39 patients. Cancer. 2000;88:2122-2134.
-
(2000)
Cancer
, vol.88
, pp. 2122-2134
-
-
Bergh, P.1
Kindblom, L.2
Gunterberg, B.3
Remotti, F.4
Ryd, W.5
Meis-Kindblom, J.6
-
15
-
-
0037381276
-
Chordoma of the skull base: Predictors of tumor recurrence
-
Pallini R, Maira G, Pierconti F, et al. Chordoma of the skull base: predictors of tumor recurrence. J Neurosurg. 2003;98: 812-822.
-
(2003)
J Neurosurg
, vol.98
, pp. 812-822
-
-
Pallini, R.1
Maira, G.2
Pierconti, F.3
-
16
-
-
0034142325
-
Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53
-
Chehab N, Malikzay A, Appel M, Halazonetis T. Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53. Genes Dev. 2000;14:278-288.
-
(2000)
Genes Dev
, vol.14
, pp. 278-288
-
-
Chehab, N.1
Malikzay, A.2
Appel, M.3
Halazonetis, T.4
-
17
-
-
0034142034
-
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh S, Ahn J, Tamai K, Taya Y, Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 2000;14:289-300.
-
(2000)
Genes Dev
, vol.14
, pp. 289-300
-
-
Shieh, S.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
18
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S, Ikeda M, Taya Y, Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell. 1997;91:325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
19
-
-
0033521621
-
ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
-
ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. EMBO J. 1999;18:22-27.
-
(1999)
EMBO J
, vol.18
, pp. 22-27
-
-
Honda, R.1
Yasuda, H.2
-
20
-
-
0033536063
-
ARF stabilizes p53 by blocking nucleocytoplasmic shuttling of Mdm2
-
ARF stabilizes p53 by blocking nucleocytoplasmic shuttling of Mdm2. Proc Natl Acad Sci USA. 1999;96:6937-7941.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6937-7941
-
-
Tao, W.1
Levine, A.J.2
-
21
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4A locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang Y, Xiong Y, Yarbrough W. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4A locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell. 1998;92:725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.3
-
22
-
-
0033592868
-
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
-
Khosravi R, Maya R, Gottlieb T, Oren M, Shiloh Y, Shkedy D. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage. Proc Natl Acad Sci USA. 1999;96:14973-14977.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14973-14977
-
-
Khosravi, R.1
Maya, R.2
Gottlieb, T.3
Oren, M.4
Shiloh, Y.5
Shkedy, D.6
-
23
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo C, Lastres E, Drobnjak M, et al. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res. 1994;54:794-799.
-
(1994)
Cancer Res
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Lastres, E.2
Drobnjak, M.3
-
24
-
-
0028023524
-
Altered patterns of MDM2 and TP53 expression in human bladder cancer
-
Lianes P, Orlow I, Zhang Z, et al. Altered patterns of MDM2 and TP53 expression in human bladder cancer. J Natl Cancer Inst. 1994;86:1325-1330.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1325-1330
-
-
Lianes, P.1
Orlow, I.2
Zhang, Z.3
-
25
-
-
0032568334
-
Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells
-
Capoulade C, Bressac-de Paillerets B, Lefrere I, et al. Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells. Oncogene. 1998;16:1603-1610.
-
(1998)
Oncogene
, vol.16
, pp. 1603-1610
-
-
Capoulade, C.1
Bressac-De Paillerets, B.2
Lefrere, I.3
-
26
-
-
0037118583
-
ARF enhances the defects of Mdm2 overexpression in the mammary gland
-
ARF enhances the defects of Mdm2 overexpression in the mammary gland. Oncogene. 2002;21:3525-3531.
-
(2002)
Oncogene
, vol.21
, pp. 3525-3531
-
-
Foster, C.1
Lozano, G.2
-
27
-
-
10144259344
-
MDMX: A novel p53-binding protein with some functional properties of MDM2
-
Shvarts A, Steegenga W, Riteco N, et al. MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 1996;15:5349-5357.
-
(1996)
EMBO J
, vol.15
, pp. 5349-5357
-
-
Shvarts, A.1
Steegenga, W.2
Riteco, N.3
-
28
-
-
0343819885
-
Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification
-
Riemenschneider M, Buschges R, Wolter M, et al. Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification. Cancer Res. 1999;59:6091-6096.
-
(1999)
Cancer Res
, vol.59
, pp. 6091-6096
-
-
Riemenschneider, M.1
Buschges, R.2
Wolter, M.3
-
29
-
-
0027956208
-
Enhanced translation: A novel mechanism of mdm2 oncoprotein overexpression identified in human tumor cells
-
Landers J, Haines D, Strauss JI, George D. Enhanced translation: a novel mechanism of mdm2 oncoprotein overexpression identified in human tumor cells. Oncogene. 1994;9:2745-2750.
-
(1994)
Oncogene
, vol.9
, pp. 2745-2750
-
-
Landers, J.1
Haines, D.2
Strauss, J.I.3
George, D.4
-
30
-
-
0027179604
-
Identification and characterization of multiple mdm2 proteins and mdm2 p53 protein complexes
-
Olson D, Marechal V, Momand J, Chen J, Romocki C, Levine A. Identification and characterization of multiple mdm2 proteins and mdm2 p53 protein complexes. Oncogene. 1993; 8:2353-2360.
-
(1993)
Oncogene
, vol.8
, pp. 2353-2360
-
-
Olson, D.1
Marechal, V.2
Momand, J.3
Chen, J.4
Romocki, C.5
Levine, A.6
-
31
-
-
0032485420
-
High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities
-
Wurl P, Meye A, Schmidt H, et al. High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities. Oncogene. 1998;16:1183-1185.
-
(1998)
Oncogene
, vol.16
, pp. 1183-1185
-
-
Wurl, P.1
Meye, A.2
Schmidt, H.3
-
32
-
-
0028334197
-
Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas
-
Patterson H, Gill S, Fisher C, et al. Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas. Br J Cancer. 1994;69:1052-1058.
-
(1994)
Br J Cancer
, vol.69
, pp. 1052-1058
-
-
Patterson, H.1
Gill, S.2
Fisher, C.3
-
33
-
-
0032417695
-
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
-
Jones S, Hancock A, Vogel H, Donehower L, Bradley A. Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis. Proc Natl Acad Sci USA. 1998;22:15608-15612.
-
(1998)
Proc Natl Acad Sci USA
, vol.22
, pp. 15608-15612
-
-
Jones, S.1
Hancock, A.2
Vogel, H.3
Donehower, L.4
Bradley, A.5
-
34
-
-
0029824669
-
Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancer
-
Sigalas I, Calvert A, Anderson J, Neal D, Lunec J. Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer. Nat Med. 1996;2:912-917.
-
(1996)
Nat Med
, vol.2
, pp. 912-917
-
-
Sigalas, I.1
Calvert, A.2
Anderson, J.3
Neal, D.4
Lunec, J.5
-
35
-
-
0030893707
-
Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors
-
Cordon-Cardo C, Zhang Z, Dalbagni G, et al. Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors. Cancer Res. 1997;57:1217-1221.
-
(1997)
Cancer Res
, vol.57
, pp. 1217-1221
-
-
Cordon-Cardo, C.1
Zhang, Z.2
Dalbagni, G.3
-
36
-
-
0032402167
-
Altered p53 is associated with aggressive behavior of chondrosarcoma: A long term follow-up study
-
Oshiro Y, Chaturvedi V, Hayden D, et al. Altered p53 is associated with aggressive behavior of chondrosarcoma: a long term follow-up study. Cancer. 1998;83:2324-2334.
-
(1998)
Cancer
, vol.83
, pp. 2324-2334
-
-
Oshiro, Y.1
Chaturvedi, V.2
Hayden, D.3
-
37
-
-
0034663196
-
Prognostic impact of p53 status in Ewing sarcoma
-
de Alava E, Antonescu CR, Panizo A, et al. Prognostic impact of p53 status in Ewing sarcoma. Cancer. 2000;89: 783-792.
-
(2000)
Cancer
, vol.89
, pp. 783-792
-
-
De Alava, E.1
Antonescu, C.R.2
Panizo, A.3
-
38
-
-
0029810442
-
Prognosis is correlated with p53 mutation type for soft tissue sarcoma patients
-
Taubert H, Meye A, Wurl P. Prognosis is correlated with p53 mutation type for soft tissue sarcoma patients. Cancer Res. 1996;56:4134-4136.
-
(1996)
Cancer Res
, vol.56
, pp. 4134-4136
-
-
Taubert, H.1
Meye, A.2
Wurl, P.3
|