Production of monoclonal antibody against FimA protein from Porphyromonas gingivalis in rice cell suspension culture

Plant Cell, Tissue and Organ Culture

Volumn 118, Issue 2, 2014, Pages 293-304

  Kim, Bang Geul ^a   Kim, Sae Hae ^a   Kim, Nan Sun ^a   Huy, Nguyen Xuan ^b   Choi, Young Suk ^c   Lee, Jin Yong ^c   Jang, Yong Suk ^a   Yang, Moon Sik ^a   Kim, Tae Geum ^a  

^a Chonbuk National University   (South Korea)

^b HUE UNIVERSITY   (Viet Nam)

^c Kyung Hee University   (South Korea)

Author keywords

Fimbriae; Passive immunization; Periodontal disease; Plant produced monoclonal antibody; Rice amylase 3D promoter system

Indexed keywords

AFFINITY CHROMATOGRAPHY; BACTERIA; CELL CULTURE; IMMUNIZATION; PROTEINS; PURIFICATION; SURFACE PLASMON RESONANCE;

AGROINFILTRATION; FIMBRIAE; PASSIVE IMMUNIZATION; PERIODONTAL DISEASE; POLYMORPHONUCLEAR NEUTROPHILS; RICE AMYLASE 3D PROMOTER SYSTEM; SUSPENSION CULTURES; TOBACCO PLANTS;

MONOCLONAL ANTIBODIES;

BACTERIA (MICROORGANISMS); NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM; PORPHYROMONAS GINGIVALIS;

EID: 84903905078     PISSN: 01676857     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11240-014-0481-9     Document Type: Article

References (48)

1. Amano A (2003) Molecular interaction of Porphyromonas gingivalis with host cells: implication for the microbial pathogenesis of periodontal disease. J Periodontol 74: 90-96.
2. Amano A, Ishimoto T, Tamagawa H, Shizuishi S (1992) Role of superoxide dismutase in resistance of Porphyromonas gingivalis to killing by polymorphonuclear leukocytes. Infect Immun 60: 712-714.
3. Burt B, Research, Science and Therapy Committee of the American Academy of Periodontology. (2005) Position paper: epidemiology of periodontal diseases. J Periodontol 76: 1406-1419.
4. Casadevall A (2002) Passive antibody administration (immediate immunity) as a specific defense against biological weapons. Emerg Infect Dis 8: 833-841.
5. Chen MH, Liu FF, Chen YR, Wu HK, Yu SM (1994) Expression of alpha-amylases, carbohydrate metabolism, and autophagy in cultured rice cells is coordinately regulated by sugar nutrient. Plant J 6: 625-636.
6. Chen PW, Lu CA, Yu TS, Tseng TH, Wang CS, Yu SM (2002) Rice alpha-amylase transcriptional enhancers direct multiple mode regulation of promoters in transgenic rice. J Biol Chem 277: 13641-13649.
7. De Neve M, De Loose M, Jacobs A, van Houdt H, Kaluza B, Weidle U, van Montagu M, Depicker A (1993) Assembly of an antibody and its derived antibody fragment in Nicotiana and Arabidopsis. Transgenic Res 2: 227-237.
8. Duncan MJ, Nakao S, Skobe Z, Xie H (1993) Interactions of Porphyromonas gingivalis with epithelial cells. Infect Immun 61: 2260-2265.
9. Fecker L, Kaufmann A, Commandeur U, Commandeur J, Koenig R, Burgermeister W (1996) Expression of single-chain antibody fragments (scFv) specific for beet necrotic yellow vein virus coat protein or 25 kDa protein in Escherichia coli and Nicotiana benthamiana. Plant Mol Biol 32: 979-986.
10. Hamada N, Watanabe K, Sasakawa C, Yoshikawa M, Yoshimura F, Umemoto T (1994) Construction and characterization of a fimA mutant of Porphyromonas gingivalis. Infect Immun 62: 1696-1704.
11. Hiatt A, Cafferkey R, Bowdish K (1989) Production of antibodies in transgenic plants. Nature 342: 76-78.
12. Hosogi Y, Duncan MJ (2005) Gene expression in Porphyromonas gingivalis after contact with human epithelial cells. Infect Immun 73: 2327-2335.
13. Huy NX, Kim SH, Yang MS, Kim TG (2012) Immunogenicity of a neutralizing epitope from porcine epidemic diarrhea virus-M cell targeting ligand fusion protein expressed in transgenic rice calli. Plant Cell Rep 31: 1933-1942.
14. Isogai H, Yoshimura F, Suzuki T, Kagota W, Takano K (1988) Specific inhibition of adherence of an oral strain of Bacteroides gingivalis 381 to epithelial cells by monoclonal antibodies against the bacterial fimbriae. Arch Oral Biol 33: 479-485.
15. Kim NS, Kim TG, Kim OH, Ko EM, Jang YS, Jung ES, Kwon TH, Yang MS (2008a) Improvement of recombinant hGM-CSF production by suppression of cysteine proteinase gene expression using RNA interference in a transgenic rice culture. Plant Mol Biol 68: 263-275.
16. Kim TG, Lee HJ, Jang YS, Shin YJ, Kwon TH, Yang MS (2008b) Co-expression of proteinase inhibitor enhances recombinant human granulocyte-macrophage colony stimulating factor production in transgenic rice cell suspension culture. Protein Expr Purif 61: 117-121.
17. Kim TG, Huy NX, Kim MY, Jeong DK, Jang YS, Yang MS, Langridge WH, Lee JY (2009) Immunogenicity of a cholera toxin B subunit Porphyromonas gingivalis fimbrial antigen fusion protein expressed in E. coli. Mol Biotechnol 41: 157-164.
18. Kim NS, Yu HY, Chung ND, Shin YJ, Kwon TH, Yang MS (2011) Production of functional recombinant bovine trypsin in transgenic rice cell suspension cultures. Protein Expr Purif 76: 121-126.
19. Kim MY, Yang MS, Kim TG (2012a) Expression of a consensus dengue virus envelope protein domain III in transgenic callus of rice. Plant Cell Tissue Organ Cult 109: 509-515.
20. Kim TG, Kim BG, Jeong DG, Jang YS, Lee JY, Yang MS (2012b) Production of monoclonal antibodies against the FimA protein of Porphyromonas gingivalis in Nicotiana benthamiana. Biotechnol Bioprocess Eng 17: 236-241.
21. Kim MY, Chung ND, Yang MS, Kim TG (2013a) Expression of cholera toxin B subunit and consensus dengue virus envelope protein domain III fusion gene in transgenic rice callus. Plant Cell Tissue Organ Cult 112: 311-320.
22. Kim NS, Jang SH, Yu HY, Chung ND, Kwon TH, Yang MS, Kim TG (2013b) Amylase and cysteine proteinase gene knockdown in rice cells using RNA interference for enhancing production of recombinant proteins. Plant Cell Tissue Organ Cul0074 114: 97-107.
23. Kirakodu SS, Govindaswami M, Novak MJ, Ebersole JL, Novak KF (2008) Optimizing qPCR for the quantification of periodontal pathogens in a complex plaque biofilm. Open Dent J 2: 49-55.
24. Kobayashi T, Yamamoto K, Suqita N, van Spriel AB, Kaneko S, van de Winkel JG, Yoshie H (2001) Effective in vitro clearance of Porphyromonas gingivalis by Fc alpha receptor I (CD89) on gingival crevicular neutrophils. Infect Immun 69: 2935-2942.
25. Koh EM, Kim Ju, Kim TG, Moon JH, Oh JH, Lee JY, Jang YS (2011) Cloning and characterization of heavy and light chain genes encoding the FimA-specific monoclonal antibodies that inhibit Porphyromonas gingivalis adhesion. Microbiol Immunol 55: 199-210.
26. Lamont RJ, Jenkinson HF (1998) Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol Mol Biol Rev 62: 1244-1263.
27. Lamont RJ, Chan A, Belton CM, Izutsu KT, Vasel D, Weinberg A (1995) Porphyromonas gingivalis invasion of gingival epithelial cells. Infect Immun 63: 3878-3885.
28. Larrick JW, Yu L, Naftzger C, Jaiswal S, Wycoff K (2001) Production of secretory IgA antibodies in plants. Biomol Eng 18: 87-94.
29. Lee JY, Sojar HT, Bedi GS, Genco RJ (1992) Synthetic peptides analogous to the fimbrillin sequence inhibit adherence of Porphyromonas gingivalis. Infect Immun 60: 1662-1670.
30. Luo Y, Dorf ME (2001) Isolation of mouse neutrophils. Curr Protoc Immunol. Chapter 3: p. Unit, pp 3-20.
31. Ma JK, Hiatt A, Hein M, Vine ND, Wang F, Stabila P, van Dolleweerd C, Mostov K, Lehner T (1995) Generation and assembly of secretory antibodies in plants. Science 268: 716-719.
32. Ma JK, Hikmat BY, Wycoff K, Vine ND, Chargelegue D, Yu L, Hein MB, Lehner T (1998) Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans. Nat Med 4: 601-606.
33. Malek R, Fisher JG, Caleca A, Stinson M, van Oss CJ, Lee JY, Cho MI, Genco RJ, Evans RT, Dyer DW (1994) Inactivation of the Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats. J Bacteriol 176: 1052-1059.
34. Mitchell VS, Philipose NM, Sanford JP (1993) The children's vaccine initiative. National Academy Press.
35. Njoroge T, Genco RJ, Sojar HT, Hamada N, Genco CA (1997) A role for fimbriae in Porphyromonas gingivalis invasion of oral epithelial cells. Infect Immun 65: 1980-1984.
36. Ozawa S, Mirelman A, Stack ML, Walker DG, Levine OS (2012) Cost-effectiveness and economic benefits of vaccines in low- and middle-income countries: a systematic review. Vaccine 31: 96-108.
37. Sack M, Vaquero C, Sriraman R, Finnern R, Fischer R (2002) Rapid large scale production of recombinant antibodies in agro-infiltrated tobacco leaves. BioTech Int 14: 12-15.
38. Schouten A, Roosien J, De Boer JM, Wilmink A, Rosso MN, Bosch D, Stiekema WJ, Gommers FJ, Bakker J, Schots A (1997) Improving scFv antibody expression levels in the plant cytosol. FEBS Lett 415: 235-241.
39. Shin YJ, Hong SY, Kwon TH, Jang YS, Yang MS (2003) High level of expression of recombinant human granulocyte-macrophage colony stimulating factor in transgenic rice cell suspension culture. Biotechnol Bioeng 82: 778-783.
40. Shin EA, Lee JY, Kim TG, Park YK, Langridge WH (2006) Synthesis and assembly of an adjuvanted Porphyromonas gingivalis fimbrial antigen fusion protein in plants. Protein Expr Purif 47: 99-109.
41. Sojar HT, Lee JY, Genco RJ (1995) Fibronectin binding domain of P. ginvalis fimbriae. Biochem Biophys Res Commun 216: 785-792.
42. Sojar HT, Sharma A, Genco RJ (2002) Porphyromonas gingivalis fimbriae bind to cytokeratin of epithelial cells. Infect Immun 70: 96-101.
43. Sukhumavasi W, Egan CE, Denkers EY (2007) Mouse neutrophils require JNK2 MAPK for Toxoplasma gondii-induced IL-12p40 and CCL2/MCP-1 release. J Immunol 179: 3570-3577.
44. Tavladoraki P, Benvenuto E, Trinca S, De Martinis D, Cattaneo A, Galeffi P (1993) Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack. Nature 366: 469-472.
45. Thompson JA, Abdullah R, Cocking EC (1986) Protoplast culture of rice (Oryza sativa L.) using media solidified with agarose. Plant Sci 47: 123-133.
46. Umemoto I, Hamada N (2003) Characterization of biologically active cell surface components of a periodontal pathogen. The roles of major and minor fimbriae of Porphyromonas gingivalis. J Periodontol 74: 119-122.
47. Weinberg A, Belton CA, Park Y, Lamont RJ (1997) Role of fimbriae in Porphyromonas gingivalis invasion of gingival epithelial cells. Infect Immun 65: 313-316.
48. Zeitlin L, Olmsted SS, Moench TR, Co MS, Martinell BJ, Paradkar VM, Russell DR, Queen C, Cone RA, Whaley KJ (1998) A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes. Nat Biotechnol 16: 1361-1364.