Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin

International Journal of Molecular Sciences

Volumn 15, Issue 7, 2014, Pages 11941-11956

  Lee, You Jin ^a   Lee, Ju Hee ^a   Moon, Ji Hong ^a   Park, Sang Youel ^a  

^a Chonbuk National University   (South Korea)

Author keywords

Bax translocation; HIF 1 (hypoxia inducible factor 1 ); Melatonin; MTP (mitochondrial transmembrane potential); PHD2 (prolyl hydroxylase 2); TRAIL (tumor necrosis factor related apoptosis inducing ligand)

Indexed keywords

ANNEXIN; CASPASE 8; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INHIBITOR OF APOPTOSIS PROTEIN; LACTATE DEHYDROGENASE; MELATONIN; PROTEIN P53; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; ANTIOXIDANT; EGLN1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; PROTEIN BCL 2; PROTEIN BCL X; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOFLUORESCENCE TEST; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; NICK END LABELING; PROTEIN EXPRESSION; TUMOR CELL; UPREGULATION; WESTERN BLOTTING; CELL HYPOXIA; DRUG EFFECTS; GENETICS; METABOLISM; TUMOR CELL LINE;

ANTIOXIDANTS; APOPTOSIS; BCL-X PROTEIN; CELL HYPOXIA; CELL LINE, TUMOR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; MELATONIN; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84903904350     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150711941     Document Type: Article

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