메뉴 건너뛰기




Volumn 11, Issue 2, 2014, Pages 92-100

Research progress on the anticarcinogenic actions and mechanisms of ellagic acid

Author keywords

Cancer; Ellagic acid (EA); Mechanism

Indexed keywords

CARCINOGEN; ELLAGIC ACID;

EID: 84903894427     PISSN: 20953941     EISSN: None     Source Type: Journal    
DOI: 10.7497/j.issn.2095-3941.2014.02.004     Document Type: Review
Times cited : (143)

References (66)
  • 1
    • 63749101977 scopus 로고    scopus 로고
    • Boyle P, Levin B. eds. International Agency for Research on Cancer
    • Boyle P, Levin B. eds. World Cancer Report 2008. International Agency for Research on Cancer, 1-260.
    • World Cancer Report 2008 , pp. 1-260
  • 2
    • 84903900033 scopus 로고    scopus 로고
    • http://www.who.int/gho/ncd/mortality_morbidity/cancer/en/index.html
  • 3
    • 84859968476 scopus 로고    scopus 로고
    • Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction
    • Ramasamy S, Abdul Wahab N, Zainal Abidin N, Manickam S, Zakaria Z. Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction. PLoS One 2012;7:e34793.
    • (2012) PLoS One , vol.7
    • Ramasamy, S.1    Abdul Wahab, N.2    Zainal Abidin, N.3    Manickam, S.4    Zakaria, Z.5
  • 4
    • 23044490704 scopus 로고    scopus 로고
    • Plants as a source of anti-cancer agents
    • Cragg G M, Newman D J. Plants as a source of anti-cancer agents. J Ethnopharmacol 2005;100:72-79.
    • (2005) J Ethnopharmacol , vol.100 , pp. 72-79
    • Cragg, G.M.1    Newman, D.J.2
  • 5
    • 57049115351 scopus 로고    scopus 로고
    • Drug development for liver diseases: focus on picroliv, ellagic acid and curcumin
    • Girish C, Pradhan S C. Drug development for liver diseases: focus on picroliv, ellagic acid and curcumin. Fundam Clin Pharmacol 2008;22:623-632.
    • (2008) Fundam Clin Pharmacol , vol.22 , pp. 623-632
    • Girish, C.1    Pradhan, S.C.2
  • 6
    • 0037985364 scopus 로고    scopus 로고
    • Ellagic acid content in strawberries of different cultivars and ripening stages
    • Williner M R, Pirovani M E, Güemes D R. Ellagic acid content in strawberries of different cultivars and ripening stages. J Sci Food Agric 2003;83:842-845.
    • (2003) J Sci Food Agric , vol.83 , pp. 842-845
    • Williner, M.R.1    Pirovani, M.E.2    Güemes, D.R.3
  • 7
    • 57749190032 scopus 로고    scopus 로고
    • Food ellagitannins-occurrence, effects of processing and storage
    • Bakkalbaşi E, Menteş O, Artik N. Food ellagitannins-occurrence, effects of processing and storage. Crit Rev Food Sci Nutr 2009;49:283-298.
    • (2009) Crit Rev Food Sci Nutr , vol.49 , pp. 283-298
    • Bakkalbaşi, E.1    Menteş, O.2    Artik, N.3
  • 10
    • 33344454669 scopus 로고    scopus 로고
    • Effects of cultivar, fruit number and reflected photosynthetically active radiation on Fragaria x ananassa productivity and fruit ellagic acid and ascorbic acid concentrations
    • Atkinson C J, Dodds P A, Ford Y Y, Le Mière J, Taylor J M, Blake P S, et al. Effects of cultivar, fruit number and reflected photosynthetically active radiation on Fragaria x ananassa productivity and fruit ellagic acid and ascorbic acid concentrations. Ann Bot 2006;97:429-441.
    • (2006) Ann Bot , vol.97 , pp. 429-441
    • Atkinson, C.J.1    Dodds, P.A.2    Ford, Y.Y.3    Le Mière, J.4    Taylor, J.M.5    Blake, P.S.6
  • 11
    • 84860245543 scopus 로고    scopus 로고
    • Antioxidant, antimicrobial properties and phenolics of different solvent extracts from bark, leaves and seeds of Pongamia pinnata (L.) Pierre
    • Sajid Z I, Anwar F, Shabir G, Rasul G, Alkharfy K M, Gilani A H. Antioxidant, antimicrobial properties and phenolics of different solvent extracts from bark, leaves and seeds of Pongamia pinnata (L.) Pierre. Molecules 2012;17:3917-3932.
    • (2012) Molecules , vol.17 , pp. 3917-3932
    • Sajid, Z.I.1    Anwar, F.2    Shabir, G.3    Rasul, G.4    Alkharfy, K.M.5    Gilani, A.H.6
  • 12
    • 84055217586 scopus 로고    scopus 로고
    • Chromatographic fingerprint and the simultaneous determination of five bioactive components of geranium carolinianum L. water extract by high performance liquid chromatography
    • Wu Q Y, Zhou Y, Jin X, Guan Y, Xu M, Liu L F. Chromatographic fingerprint and the simultaneous determination of five bioactive components of geranium carolinianum L. water extract by high performance liquid chromatography. Int J Mol Sci 2011;12:8740-8749.
    • (2011) Int J Mol Sci , vol.12 , pp. 8740-8749
    • Wu, Q.Y.1    Zhou, Y.2    Jin, X.3    Guan, Y.4    Xu, M.5    Liu, L.F.6
  • 13
    • 23744514964 scopus 로고    scopus 로고
    • Identification of ellagic acid conjugates and other polyphenolics in muscadine grapes by HPLC-ESI-MS
    • Lee J H, Johnson J V, Talcott S T. Identification of ellagic acid conjugates and other polyphenolics in muscadine grapes by HPLC-ESI-MS. Journal of Agricultural and Food Chemistry 2005;53:6003-6010.
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , pp. 6003-6010
    • Lee, J.H.1    Johnson, J.V.2    Talcott, S.T.3
  • 14
    • 51349096457 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by ellagitannins
    • Heber D. Multitargeted therapy of cancer by ellagitannins. Cancer Letters 2008;269:262-268.
    • (2008) Cancer Letters , vol.269 , pp. 262-268
    • Heber, D.1
  • 15
    • 84868195812 scopus 로고    scopus 로고
    • Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer
    • Wang N, Wang Z Y, Mo S L, Loo T Y, Wang D M, Luo H B, et al. Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. Breast Cancer Res Treat 2012;134:943-955.
    • (2012) Breast Cancer Res Treat , vol.134 , pp. 943-955
    • Wang, N.1    Wang, Z.Y.2    Mo, S.L.3    Loo, T.Y.4    Wang, D.M.5    Luo, H.B.6
  • 17
    • 33750735017 scopus 로고    scopus 로고
    • Antioxidant and apoptosis-inducing activities of ellagic acid
    • Han D H, Lee M J, Kim J H. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer research 2006;26:3601-3606.
    • (2006) Anticancer research , vol.26 , pp. 3601-3606
    • Han, D.H.1    Lee, M.J.2    Kim, J.H.3
  • 18
    • 54349088525 scopus 로고    scopus 로고
    • Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells
    • Edderkaoui M, Odinokova I, Ohno I, Gukovsky I, Go V L, Pandol S J, et al. Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells. World J Gastroenterol 2008;14:3672-3680.
    • (2008) World J Gastroenterol , vol.14 , pp. 3672-3680
    • Edderkaoui, M.1    Odinokova, I.2    Ohno, I.3    Gukovsky, I.4    Go, V.L.5    Pandol, S.J.6
  • 19
    • 84888369279 scopus 로고    scopus 로고
    • Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells
    • Edderkaoui M, Lugea A, Hui H, Eibl G, Lu Q Y, Moro A, et al. Ellagic Acid and Embelin Affect Key Cellular Components of Pancreatic Adenocarcinoma, Cancer, and Stellate Cells. Nutr Cancer 2013;65:1232-1244.
    • (2013) Nutr Cancer , vol.65 , pp. 1232-1244
    • Edderkaoui, M.1    Lugea, A.2    Hui, H.3    Eibl, G.4    Lu, Q.Y.5    Moro, A.6
  • 20
    • 84880513749 scopus 로고    scopus 로고
    • Ellagic acid inhibits human pancreatic cancer growth in Balb/C nude mice
    • Zhao M, Tang S N, Marsh J L, Shankar S, Srivastava R K. Ellagic acid inhibits human pancreatic cancer growth in Balb/C nude mice. Cancer Lett 2013;337:210-217.
    • (2013) Cancer Lett , vol.337 , pp. 210-217
    • Zhao, M.1    Tang, S.N.2    Marsh, J.L.3    Shankar, S.4    Srivastava, R.K.5
  • 22
    • 70349571127 scopus 로고    scopus 로고
    • Phyllanthus urinaria Increases Apoptosis and Reduces Telomerase Activity in Human Nasopharyngeal Carcinoma Cells
    • Huang S T, Wang C Y, Yang R C, Chu C J, Wu H T, Pang J H. Phyllanthus urinaria Increases Apoptosis and Reduces Telomerase Activity in Human Nasopharyngeal Carcinoma Cells. Forsch Komplementmed 2009;16:34-40.
    • (2009) Forsch Komplementmed , vol.16 , pp. 34-40
    • Huang, S.T.1    Wang, C.Y.2    Yang, R.C.3    Chu, C.J.4    Wu, H.T.5    Pang, J.H.6
  • 23
    • 84878369551 scopus 로고    scopus 로고
    • Ellagic acid checks lymphoma promotion via regulation of PKC signaling pathway
    • Mishra S, Vinayak M. Ellagic acid checks lymphoma promotion via regulation of PKC signaling pathway. Mol Biol Rep 2013;40:1417-1428.
    • (2013) Mol Biol Rep , vol.40 , pp. 1417-1428
    • Mishra, S.1    Vinayak, M.2
  • 24
    • 84899902674 scopus 로고    scopus 로고
    • Ellagic acid induces novel and atypical PKC isoforms and promotes caspase-3 dependent apoptosis by blocking energy metabolism
    • Mishra S, Vinayak M. Ellagic Acid Induces Novel and Atypical PKC Isoforms and Promotes Caspase-3 Dependent Apoptosis by Blocking Energy Metabolism. Nutr Cancer 2014;66:675-681.
    • (2014) Nutr Cancer , vol.66 , pp. 675-681
    • Mishra, S.1    Vinayak, M.2
  • 25
    • 84862167763 scopus 로고    scopus 로고
    • Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention
    • Aiyer H S, Warri A M, Wood D R E, Hilakivi-Clarke L, Clarke R. Influence of Berry Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention. J Agric Food Chem 2012;60:5693-5708.
    • (2012) J Agric Food Chem , vol.60 , pp. 5693-5708
    • Aiyer, H.S.1    Warri, A.M.2    Wood, D.R.E.3    Hilakivi-Clarke, L.4    Clarke, R.5
  • 26
    • 77953528472 scopus 로고    scopus 로고
    • Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism
    • Aiyer H S, Gupta R C. Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism. Cancer Prev Res (Phila) 2010;3:727-737.
    • (2010) Cancer Prev Res (Phila) , vol.3 , pp. 727-737
    • Aiyer, H.S.1    Gupta, R.C.2
  • 27
    • 84859736882 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative activities of anthocyanin/ellagitannin-enriched extracts from Syzygium cumini L
    • Aqil F, Gupta A, Munagala R, Jeyabalan J, Kausar H, Sharma R J, et al. Antioxidant and antiproliferative activities of anthocyanin/ellagitannin-enriched extracts from Syzygium cumini L. Nutr Cancer 2012;64:428-438.
    • (2012) Nutr Cancer , vol.64 , pp. 428-438
    • Aqil, F.1    Gupta, A.2    Munagala, R.3    Jeyabalan, J.4    Kausar, H.5    Sharma, R.J.6
  • 28
    • 0037181332 scopus 로고    scopus 로고
    • Free radical studies of ellagic acid, a natural phenolic antioxidant
    • Priyadarsini K I, Khopde S M, Kumar S S, Mohan H. Free radical studies of ellagic acid, a natural phenolic antioxidant. J Agric Food Chem 2002;50:2200-2206.
    • (2002) J Agric Food Chem , vol.50 , pp. 2200-2206
    • Priyadarsini, K.I.1    Khopde, S.M.2    Kumar, S.S.3    Mohan, H.4
  • 29
    • 0037294150 scopus 로고    scopus 로고
    • Mechanism-based in vitro screening of potential cancer chemopreventive agents
    • Gerhäuser C, Klimo K, Heiss E, Neumann I, Gamal-Eldeen A, Knauft J, et al. Mechanism-based in vitro screening of potential cancer chemopreventive agents. Mutat Res 2003;523-524:163-172.
    • (2003) Mutat Res , vol.523-524 , pp. 163-172
    • Gerhäuser, C.1    Klimo, K.2    Heiss, E.3    Neumann, I.4    Gamal-Eldeen, A.5    Knauft, J.6
  • 30
    • 78650694707 scopus 로고    scopus 로고
    • Oxidatively generated DNA damage following Cu(II)-catalysis of dopamine and related catecholamine neurotransmitters and neurotoxins: role of reactive oxygen species
    • Spencer W A, Jeyabalan J, Kichambre S, Gupta R C. Oxidatively Generated DNA Damage Following Cu(II)-Catalysis of Dopamine and Related Catecholamine Neurotransmitters and Neurotoxins: Role of Reactive Oxygen Species. Free Radic Biol Med 2011;50:139-147.
    • (2011) Free Radic Biol Med , vol.50 , pp. 139-147
    • Spencer, W.A.1    Jeyabalan, J.2    Kichambre, S.3    Gupta, R.C.4
  • 32
    • 41649085767 scopus 로고    scopus 로고
    • Dietary berries and ellagic acid prevent oxidative DNA damage and modulate expression of DNA repair genes
    • Aiyer H S, Vadhanam M V, Stoyanova R, Caprio G D, Clapper M L, Gupta R C. Dietary Berries and Ellagic Acid Prevent Oxidative DNA Damage and Modulate Expression of DNA Repair Genes. Int J Mol Sci 2008;9:327-341.
    • (2008) Int J Mol Sci , vol.9 , pp. 327-341
    • Aiyer, H.S.1    Vadhanam, M.V.2    Stoyanova, R.3    Caprio, G.D.4    Clapper, M.L.5    Gupta, R.C.6
  • 33
    • 0042762851 scopus 로고    scopus 로고
    • Intestinal epithelial cell accumulation of the cancer preventive polyphenol ellagic acid-extensive binding to protein and DNA
    • Whitley A C, Stoner G D, Darby M V, Walle T. Intestinal epithelial cell accumulation of the cancer preventive polyphenol ellagic acid-extensive binding to protein and DNA. Biochem. Pharmacol 2003; 66:907-915.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 907-915
    • Whitley, A.C.1    Stoner, G.D.2    Darby, M.V.3    Walle, T.4
  • 34
    • 0025037968 scopus 로고
    • Inhibition of N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats by ellagic acid
    • Mandal S, Stoner G D. Inhibition of N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats by ellagic acid. Carcinogenesis 1990;11:55-61.
    • (1990) Carcinogenesis , vol.11 , pp. 55-61
    • Mandal, S.1    Stoner, G.D.2
  • 35
    • 0029053406 scopus 로고
    • Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats
    • Siglin J C, Barch D H, Stoner G D. Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats. Carcinogenesis 1995;16:1101-1106.
    • (1995) Carcinogenesis , vol.16 , pp. 1101-1106
    • Siglin, J.C.1    Barch, D.H.2    Stoner, G.D.3
  • 36
    • 33746502503 scopus 로고    scopus 로고
    • Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms
    • Stoner G D, Chen T, Kresty L A, Aziz R M, Reinemann T, Nines R. Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms. Nutr Cancer 2006;54:33-46.
    • (2006) Nutr Cancer , vol.54 , pp. 33-46
    • Stoner, G.D.1    Chen, T.2    Kresty, L.A.3    Aziz, R.M.4    Reinemann, T.5    Nines, R.6
  • 38
    • 38849088073 scopus 로고    scopus 로고
    • Ellagitannin-rich pomegranate extract inhibits angiogenesis in prostate cancer in vitro and in vivo
    • Sartippour M R, Seeram N P, Rao J Y, Moro A, Harris D M, Henning S M, et al. Ellagitannin-rich pomegranate extract inhibits angiogenesis in prostate cancer in vitro and in vivo. Int J Oncol 2008;32:475-480.
    • (2008) Int J Oncol , vol.32 , pp. 475-480
    • Sartippour, M.R.1    Seeram, N.P.2    Rao, J.Y.3    Moro, A.4    Harris, D.M.5    Henning, S.M.6
  • 39
    • 79955757511 scopus 로고    scopus 로고
    • Zinc-chelation contributes to the anti-angiogenic effect of ellagic acid on inhibiting MMP-2 activity, cell migration and tube formation
    • Huang S T, Yang R C, Wu H T, Wang C N, Pang J S. Zinc-Chelation Contributes to the Anti-Angiogenic Effect of Ellagic Acid on Inhibiting MMP-2 Activity, Cell Migration and Tube Formation. Plos One 2011;6:e18986.
    • (2011) Plos One , vol.6
    • Huang, S.T.1    Yang, R.C.2    Wu, H.T.3    Wang, C.N.4    Pang, J.S.5
  • 40
    • 84876585707 scopus 로고    scopus 로고
    • Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer
    • Rocha A, Wang L, Penichet M, Martins-Green M. Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer. Breast Cancer Res Treat 2012;136:647-658.
    • (2012) Breast Cancer Res Treat , vol.136 , pp. 647-658
    • Rocha, A.1    Wang, L.2    Penichet, M.3    Martins-Green, M.4
  • 41
    • 84867567728 scopus 로고    scopus 로고
    • Specific pomegranate juice components as potential inhibitors of prostate cancer metastasis
    • Wang L, Ho J, Glackin C, Martins-Green M. Specific pomegranate juice components as potential inhibitors of prostate cancer metastasis. Transl Oncol 2012;5:344-355.
    • (2012) Transl Oncol , vol.5 , pp. 344-355
    • Wang, L.1    Ho, J.2    Glackin, C.3    Martins-Green, M.4
  • 42
    • 84874642641 scopus 로고    scopus 로고
    • The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages
    • Capece D, Fischietti M, Verzella D, Gaggiano A, Cicciarelli G, Tessitore A, et al. The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages. Biomed Res Int 2013;2013:187204.
    • (2013) Biomed Res Int , vol.2013 , pp. 187204
    • Capece, D.1    Fischietti, M.2    Verzella, D.3    Gaggiano, A.4    Cicciarelli, G.5    Tessitore, A.6
  • 43
    • 84874607911 scopus 로고    scopus 로고
    • HBx-induced NF-κB signaling in liver cells is potentially mediated by the ternary complex of HBx with p22-FLIP and NEMO
    • Lim K H, Choi H S, Park Y K, Park E S, Shin G C, Kim D H, et al. HBx-induced NF-κB signaling in liver cells is potentially mediated by the ternary complex of HBx with p22-FLIP and NEMO. PLoS One 2013;8:e57331.
    • (2013) PLoS One , vol.8
    • Lim, K.H.1    Choi, H.S.2    Park, Y.K.3    Park, E.S.4    Shin, G.C.5    Kim, D.H.6
  • 44
    • 33646562819 scopus 로고    scopus 로고
    • Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma
    • Branda M, Wands J R. Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma. Hepatology 2006;43:891-902.
    • (2006) Hepatology , vol.43 , pp. 891-902
    • Branda, M.1    Wands, J.R.2
  • 45
    • 33745517203 scopus 로고    scopus 로고
    • Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis
    • Kremsdorf D, Soussan P, Paterlini-Brechot P, Brechot C. Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis. Oncogene 2006;25:3823-3833.
    • (2006) Oncogene , vol.25 , pp. 3823-3833
    • Kremsdorf, D.1    Soussan, P.2    Paterlini-Brechot, P.3    Brechot, C.4
  • 46
    • 79955585058 scopus 로고    scopus 로고
    • Cytokines, inflammation and colon cancer
    • Klampfer L. Cytokines, inflammation and colon cancer. Curr Cancer Drug Targets 2011;11:451-464.
    • (2011) Curr Cancer Drug Targets , vol.11 , pp. 451-464
    • Klampfer, L.1
  • 47
    • 84884127454 scopus 로고    scopus 로고
    • Friend or foe: emerging role of nuclear factor appa-light-chain-enhancer of activated B cells in cell senescence
    • Mowla S N, Perkins N D, Jat P S. Friend or foe: emerging role of nuclear factor appa-light-chain-enhancer of activated B cells in cell senescence. Onco Targets Ther 2013;6:1221-1229.
    • (2013) Onco Targets Ther , vol.6 , pp. 1221-1229
    • Mowla, S.N.1    Perkins, N.D.2    Jat, P.S.3
  • 48
    • 26444584958 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and liver carcinogenesis
    • Arsura M, Cavin L G. Nuclear factor-kappaB and liver carcinogenesis. Cancer Lett 2005;229:157-169.
    • (2005) Cancer Lett , vol.229 , pp. 157-169
    • Arsura, M.1    Cavin, L.G.2
  • 50
    • 84902296290 scopus 로고    scopus 로고
    • Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105
    • Khan M K, Ansari I A, Khan M S. Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105. Pharmacogn Mag 2013;9:51-57.
    • (2013) Pharmacogn Mag , vol.9 , pp. 51-57
    • Khan, M.K.1    Ansari, I.A.2    Khan, M.S.3
  • 51
    • 77954730556 scopus 로고    scopus 로고
    • Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1, 2-dimethylhydrazine-induced rat colon carcinogenesis
    • Umesalma S, Sudhandiran G. Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1, 2-dimethylhydrazine-induced rat colon carcinogenesis. Basic Clin Pharmacol Toxicol 2010;107:650-655.
    • (2010) Basic Clin Pharmacol Toxicol , vol.107 , pp. 650-655
    • Umesalma, S.1    Sudhandiran, G.2
  • 53
    • 80053587355 scopus 로고    scopus 로고
    • Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy
    • Nambiar D, Rajamani P, Singh R P. Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy. Mutat Res 2011;728:139-157.
    • (2011) Mutat Res , vol.728 , pp. 139-157
    • Nambiar, D.1    Rajamani, P.2    Singh, R.P.3
  • 54
    • 24344497802 scopus 로고    scopus 로고
    • A flavonoid from medicinal plants blocks hepatitis B virus-e antigen secretion in HBV-infected hepatocytes
    • Shin M S, Kang E H, Lee Y I. A flavonoid from medicinal plants blocks hepatitis B virus-e antigen secretion in HBV-infected hepatocytes. Antiviral Res 2005;67:163-168.
    • (2005) Antiviral Res , vol.67 , pp. 163-168
    • Shin, M.S.1    Kang, E.H.2    Lee, Y.I.3
  • 55
    • 33748448459 scopus 로고    scopus 로고
    • The flavonoid ellagic acid from a medicinal herb inhibits host immune tolerance induced by the hepatitis B virus-e antigen
    • Kang E H, Kown T Y, Oh G T, Park W F, Park S I, Park S K, et al. The flavonoid ellagic acid from a medicinal herb inhibits host immune tolerance induced by the hepatitis B virus-e antigen. Antiviral Res 2006;72:100-106.
    • (2006) Antiviral Res , vol.72 , pp. 100-106
    • Kang, E.H.1    Kown, T.Y.2    Oh, G.T.3    Park, W.F.4    Park, S.I.5    Park, S.K.6
  • 56
    • 34848855545 scopus 로고    scopus 로고
    • Ellagic acid prevents cisplatin-induced oxidative stress in liver and heart tissue of rats
    • Yüce A, Ateşşahin A, Ceribaşi A O, Aksakal M. Ellagic acid prevents cisplatin-induced oxidative stress in liver and heart tissue of rats. Basic Clin Pharmacol Toxicol 2007;101:345-349.
    • (2007) Basic Clin Pharmacol Toxicol , vol.101 , pp. 345-349
    • Yüce, A.1    Ateşşahin, A.2    Ceribaşi, A.O.3    Aksakal, M.4
  • 57
    • 33845224136 scopus 로고    scopus 로고
    • The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin
    • Hayeshi R, Mutingwende I, Mavengere W, Masiyanise V, Mukanganyama S. The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem Toxicol 2007;45:286-295.
    • (2007) Food Chem Toxicol , vol.45 , pp. 286-295
    • Hayeshi, R.1    Mutingwende, I.2    Mavengere, W.3    Masiyanise, V.4    Mukanganyama, S.5
  • 58
    • 84877932636 scopus 로고    scopus 로고
    • Pomegranate juice metabolites, Ellagic acid and urolithin A, synergistically inhibit androgen-independent prostate cancer cell growth via distinct effects on cell cycle control and apoptosis
    • Vicinanza R, Zhang Y, Henning S M, Heber D. Pomegranate juice metabolites, Ellagic acid and urolithin A, synergistically inhibit androgen-independent prostate cancer cell growth via distinct effects on cell cycle control and apoptosis. Evid Based Complement Alternat Med 2013;2013:247504.
    • (2013) Evid Based Complement Alternat Med , vol.2013 , pp. 247504
    • Vicinanza, R.1    Zhang, Y.2    Henning, S.M.3    Heber, D.4
  • 59
    • 84877295491 scopus 로고    scopus 로고
    • The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP)
    • González-Sarrías A, Miguel V, Merino G, Lucas R, Morales J C, Tomás-Barberán F, et al. The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP). J Agric Food Chem 2013;61:4352-4359.
    • (2013) J Agric Food Chem , vol.61 , pp. 4352-4359
    • González-Sarrías, A.1    Miguel, V.2    Merino, G.3    Lucas, R.4    Morales, J.C.5    Tomás-Barberán, F.6
  • 61
    • 38949177014 scopus 로고    scopus 로고
    • Ellagic acid, pomegranate and prostate cancer-a mini review
    • Bell C, Hawthorne S. Ellagic acid, pomegranate and prostate cancer-a mini review. J Pharm Pharmacol 2008;60:139-144.
    • (2008) J Pharm Pharmacol , vol.60 , pp. 139-144
    • Bell, C.1    Hawthorne, S.2
  • 62
    • 33847178373 scopus 로고    scopus 로고
    • Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats
    • Sharma G, Italia J L, Sonaje K, Tikoo K, Ravi Kumar M N. Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats. J Control Release 2007;118:27-37.
    • (2007) J Control Release , vol.118 , pp. 27-37
    • Sharma, G.1    Italia, J.L.2    Sonaje, K.3    Tikoo, K.4    Ravi Kumar, M.N.5
  • 63
    • 33645758753 scopus 로고    scopus 로고
    • Sustained release nanoparticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration
    • Bala I, Bhardwaj V, Hariharan S, Kharade S V, Roy N, Ravi Kumar M N. Sustained release nanoparticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration. J Drug Target 2006;14:27-34.
    • (2006) J Drug Target , vol.14 , pp. 27-34
    • Bala, I.1    Bhardwaj, V.2    Hariharan, S.3    Kharade, S.V.4    Roy, N.5    Ravi Kumar, M.N.6
  • 64
    • 0034879018 scopus 로고    scopus 로고
    • Application of Eudragit P-4135F for the delivery of ellagic acid to the rat lower small intestine
    • Jeong Y I, Prasad Yv R, Ohno T, Yoshikawa Y, Shibata N, Kato S, et al. Application of Eudragit P-4135F for the delivery of ellagic acid to the rat lower small intestine. J Pharm Pharmacol 2001;53:1079-1085.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 1079-1085
    • Jeong, Y.I.1    Prasad, Y.V.R.2    Ohno, T.3    Yoshikawa, Y.4    Shibata, N.5    Kato, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.