메뉴 건너뛰기




Volumn 44, Issue 7, 2014, Pages 812-817

Efficacy of ezetimibe for reducing serum low-density lipoprotein cholesterol levels resistant to lifestyle intervention in patients with non-alcoholic fatty liver disease

Author keywords

Diet; Dyslipidemia; Exercise; Ezetimibe; Low density lipoprotein cholesterol

Indexed keywords

ALANINE AMINOTRANSFERASE; EZETIMIBE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84903850162     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/hepr.12176     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma
    • Bugianesi E, Leone N, Vanni E etal. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gatroenterology 2002; 123: 134-140.
    • (2002) Gatroenterology , vol.123 , pp. 134-140
    • Bugianesi, E.1    Leone, N.2    Vanni, E.3
  • 2
    • 22344453700 scopus 로고    scopus 로고
    • Natural history of NAFLD: remarkably benign in the absence of cirrhosis
    • Day CP. Natural history of NAFLD: remarkably benign in the absence of cirrhosis. Gatroenterology 2005; 129: 375-378.
    • (2005) Gatroenterology , vol.129 , pp. 375-378
    • Day, C.P.1
  • 3
    • 75449088414 scopus 로고    scopus 로고
    • Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
    • Söderberg C, Stål P, Askling J etal. Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. Hepatology 2010; 51: 595-602.
    • (2010) Hepatology , vol.51 , pp. 595-602
    • Söderberg, C.1    Stål, P.2    Askling, J.3
  • 4
    • 0025178612 scopus 로고
    • The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years
    • Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology 1990; 11: 74-80.
    • (1990) Hepatology , vol.11 , pp. 74-80
    • Powell, E.E.1    Cooksley, W.G.2    Hanson, R.3    Searle, J.4    Halliday, J.W.5    Powell, L.W.6
  • 5
    • 77952680758 scopus 로고    scopus 로고
    • Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study
    • Speliotes EK, Massaro JM, Hoffmann U etal. Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study. Hepatology 2010; 51: 1979-1987.
    • (2010) Hepatology , vol.51 , pp. 1979-1987
    • Speliotes, E.K.1    Massaro, J.M.2    Hoffmann, U.3
  • 6
    • 80052175601 scopus 로고    scopus 로고
    • Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects
    • Taskinen MR, Adiels M, Westerbacka J etal. Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects. Arterioscler Thromb Vasc Biol 2011; 31: 2144-2150.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2144-2150
    • Taskinen, M.R.1    Adiels, M.2    Westerbacka, J.3
  • 7
    • 73449118215 scopus 로고    scopus 로고
    • A pilot trial of body weight reduction for nonalcoholic fatty liver disease with a home-based lifestyle modification intervention delivered in collaboration with interdisciplinary medical staff
    • Oza N, Eguchi Y, Mizuta T etal. A pilot trial of body weight reduction for nonalcoholic fatty liver disease with a home-based lifestyle modification intervention delivered in collaboration with interdisciplinary medical staff. J Gastroenterol 2009; 44: 1203-1208.
    • (2009) J Gastroenterol , vol.44 , pp. 1203-1208
    • Oza, N.1    Eguchi, Y.2    Mizuta, T.3
  • 8
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzén LE, Mathiesen UL etal. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006; 44: 865-873.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzén, L.E.2    Mathiesen, U.L.3
  • 10
    • 58849134985 scopus 로고    scopus 로고
    • Long-term follow-up of patients with nonalcoholic fatty liver
    • Rafiq N, Bai C, Fang Y etal. Long-term follow-up of patients with nonalcoholic fatty liver. Clin Gastroenterol Hepatol 2009; 7: 234-238.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 234-238
    • Rafiq, N.1    Bai, C.2    Fang, Y.3
  • 11
    • 20444371945 scopus 로고    scopus 로고
    • The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
    • Garcia-Calvo M, Lisnock J, Bull HG etal. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci U S A 2005; 102: 8132-8137.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8132-8137
    • Garcia-Calvo, M.1    Lisnock, J.2    Bull, H.G.3
  • 12
    • 34249005579 scopus 로고    scopus 로고
    • Effect of ezetimibe monotherapy on the concentration of lipoprotein subfractions in patients with primary dyslipidaemia
    • Kalogirou M, Tsimihodimos V, Gazi I etal. Effect of ezetimibe monotherapy on the concentration of lipoprotein subfractions in patients with primary dyslipidaemia. Curr Med Res Opin 2007; 23: 1169-1176.
    • (2007) Curr Med Res Opin , vol.23 , pp. 1169-1176
    • Kalogirou, M.1    Tsimihodimos, V.2    Gazi, I.3
  • 13
    • 77954366025 scopus 로고    scopus 로고
    • Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: an open-label, pilot study
    • Yoneda M, Fujita K, Nozaki Y etal. Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: an open-label, pilot study. Hepatol Res 2010; 40: 613-621.
    • (2010) Hepatol Res , vol.40 , pp. 613-621
    • Yoneda, M.1    Fujita, K.2    Nozaki, Y.3
  • 14
    • 78651473467 scopus 로고    scopus 로고
    • Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease
    • Park H, Shima T, Yamaguchi K etal. Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease. J Gastroenterol 2011; 46: 101-107.
    • (2011) J Gastroenterol , vol.46 , pp. 101-107
    • Park, H.1    Shima, T.2    Yamaguchi, K.3
  • 15
    • 77952674608 scopus 로고    scopus 로고
    • Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet
    • Chan DC, Watts GF, Gan SK, Ooi EM, Barrett PH. Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet. Diabetes Care 2010; 33: 1134-1139.
    • (2010) Diabetes Care , vol.33 , pp. 1134-1139
    • Chan, D.C.1    Watts, G.F.2    Gan, S.K.3    Ooi, E.M.4    Barrett, P.H.5
  • 17
    • 0036729447 scopus 로고    scopus 로고
    • The utility of radiological imaging in nonalcoholic fatty liver disease
    • Saadeh S, Younossi ZM, Remer EM etal. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology 2002; 123: 745-750.
    • (2002) Gastroenterology , vol.123 , pp. 745-750
    • Saadeh, S.1    Younossi, Z.M.2    Remer, E.M.3
  • 18
    • 0026520044 scopus 로고
    • Charting of daily weight pattern reinforces maintenance of weight reduction in moderately obese patients
    • Fujimoto K, Sakata T, Etou H etal. Charting of daily weight pattern reinforces maintenance of weight reduction in moderately obese patients. Am J Med Sci 1992; 303: 145-150.
    • (1992) Am J Med Sci , vol.303 , pp. 145-150
    • Fujimoto, K.1    Sakata, T.2    Etou, H.3
  • 19
    • 0033822207 scopus 로고    scopus 로고
    • Compendium of physical activities: an update of activity codes and MET intensities
    • Ainsworth BE, Haskell WL, Whitt MC etal. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 2000; 32: S498-504.
    • (2000) Med Sci Sports Exerc , vol.32
    • Ainsworth, B.E.1    Haskell, W.L.2    Whitt, M.C.3
  • 20
    • 0032197935 scopus 로고    scopus 로고
    • Development of a 12-min tredmill walk test at a self-selected pace for the evaluation of cardiorespiratory fitness in adult men
    • Nakagaichi M, Tanaka K. Development of a 12-min tredmill walk test at a self-selected pace for the evaluation of cardiorespiratory fitness in adult men. Appl Hum Sci 1998; 17: 281-288.
    • (1998) Appl Hum Sci , vol.17 , pp. 281-288
    • Nakagaichi, M.1    Tanaka, K.2
  • 22
    • 84903852187 scopus 로고    scopus 로고
    • Ministry of Health, Labour and Welfare of Japan. Exercise and physical activity reference for health promotion. Available at:
    • Ministry of Health, Labour and Welfare of Japan. Exercise and physical activity reference for health promotion 2006. Available at: http://www.nih.go.jp/eiken/programs/pdf/epar2006.pdf.
    • (2006)
  • 23
    • 34250681801 scopus 로고    scopus 로고
    • Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese
    • Teramoto T, Sasaki J, Ueshima H etal. Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese. J Atheroscler Thromb 2007; 14: 45-50.
    • (2007) J Atheroscler Thromb , vol.14 , pp. 45-50
    • Teramoto, T.1    Sasaki, J.2    Ueshima, H.3
  • 24
    • 0034453225 scopus 로고    scopus 로고
    • Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha
    • Tobin KA, Steineger HH, Alberti S etal. Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. Mol Endocrinol 2000; 14: 741-752.
    • (2000) Mol Endocrinol , vol.14 , pp. 741-752
    • Tobin, K.A.1    Steineger, H.H.2    Alberti, S.3
  • 25
    • 3843061127 scopus 로고    scopus 로고
    • Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
    • Chen G, Liang G, Ou J, Goldstein JL, Brown MS. Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci U S A 2004; 101: 11245-11250.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11245-11250
    • Chen, G.1    Liang, G.2    Ou, J.3    Goldstein, J.L.4    Brown, M.S.5
  • 26
    • 0037302979 scopus 로고    scopus 로고
    • Effect of weight loss on postprandial lipemia and low-density lipoprotein receptor binding in overweight men
    • James AP, Watts GF, Barrett PH etal. Effect of weight loss on postprandial lipemia and low-density lipoprotein receptor binding in overweight men. Metabolism 2003; 52: 136-141.
    • (2003) Metabolism , vol.52 , pp. 136-141
    • James, A.P.1    Watts, G.F.2    Barrett, P.H.3
  • 27
    • 0036136809 scopus 로고    scopus 로고
    • Long-term effects of ad libitum low-fat, high-carbohydrate diets on body weight and serum lipids in overweight subjects with metabolic syndrome
    • Poppitt SD, Keogh GF, Prentice AM etal. Long-term effects of ad libitum low-fat, high-carbohydrate diets on body weight and serum lipids in overweight subjects with metabolic syndrome. Am J Clin Nutr 2002; 75: 11-20.
    • (2002) Am J Clin Nutr , vol.75 , pp. 11-20
    • Poppitt, S.D.1    Keogh, G.F.2    Prentice, A.M.3
  • 28
    • 0026486182 scopus 로고
    • Prospective, randomized, controlled comparison of the effects of low-fat and low-fat plus high-fiber diets on serum lipid concentrations
    • Anderson JW, Garrity TF, Wood CL, Whitis SE, Smith BM, Oeltgen PR. Prospective, randomized, controlled comparison of the effects of low-fat and low-fat plus high-fiber diets on serum lipid concentrations. Am J Clin Nutr 1992; 56: 887-894.
    • (1992) Am J Clin Nutr , vol.56 , pp. 887-894
    • Anderson, J.W.1    Garrity, T.F.2    Wood, C.L.3    Whitis, S.E.4    Smith, B.M.5    Oeltgen, P.R.6
  • 29
    • 0029924138 scopus 로고    scopus 로고
    • Role of cholesterol in regulating apolipoprotein B secretion by the liver
    • Thompson GR, Naoumova RP, Watts GF. Role of cholesterol in regulating apolipoprotein B secretion by the liver. J Lipid Res 1996; 37: 439-447.
    • (1996) J Lipid Res , vol.37 , pp. 439-447
    • Thompson, G.R.1    Naoumova, R.P.2    Watts, G.F.3
  • 30
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • Chalasani N, Younossi Z, Lavine JE etal. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012; 55: 2005-2023.
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3
  • 31
    • 55649083505 scopus 로고    scopus 로고
    • Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia
    • Hyogo H, Tazuma S, Arihiro K etal. Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia. Metabolism 2008; 57: 1711-1718.
    • (2008) Metabolism , vol.57 , pp. 1711-1718
    • Hyogo, H.1    Tazuma, S.2    Arihiro, K.3
  • 32
    • 75149137084 scopus 로고    scopus 로고
    • Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease
    • Abel T, Fehér J, Dinya E, Eldin MG, Kovács A. Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease. Med Sci Monit 2009; 15: MS6-11.
    • (2009) Med Sci Monit , vol.15
    • Abel, T.1    Fehér, J.2    Dinya, E.3    Eldin, M.G.4    Kovács, A.5
  • 33
    • 28344436469 scopus 로고    scopus 로고
    • Rosuvastatin as a novel treatment of non-alcoholic fatty liver disease in hyperlipidemic patients
    • Antonopoulos S, Mikros S, Mylonopoulou M, Kokkoris S, Giannoulis G. Rosuvastatin as a novel treatment of non-alcoholic fatty liver disease in hyperlipidemic patients. Atherosclerosis 2006; 184: 233-234.
    • (2006) Atherosclerosis , vol.184 , pp. 233-234
    • Antonopoulos, S.1    Mikros, S.2    Mylonopoulou, M.3    Kokkoris, S.4    Giannoulis, G.5
  • 34
    • 39149098871 scopus 로고    scopus 로고
    • Statins in hepatobiliary diseases: effects, indications and risks
    • Lowyck I, Fevery J. Statins in hepatobiliary diseases: effects, indications and risks. Acta Gastroenterol Belg 2007; 70: 381-388.
    • (2007) Acta Gastroenterol Belg , vol.70 , pp. 381-388
    • Lowyck, I.1    Fevery, J.2
  • 36
    • 4344593276 scopus 로고    scopus 로고
    • Efficacy of omega-3 fatty acids, atorvastatin and orlistat in non-alcoholic fatty liver disease with dyslipidemia
    • Hatzitolios A, Savopoulos C, Lazaraki G etal. Efficacy of omega-3 fatty acids, atorvastatin and orlistat in non-alcoholic fatty liver disease with dyslipidemia. Indian J Gastroenterol 2004; 23: 131-134.
    • (2004) Indian J Gastroenterol , vol.23 , pp. 131-134
    • Hatzitolios, A.1    Savopoulos, C.2    Lazaraki, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.