Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation

Journal of Controlled Release

Volumn 189, Issue , 2014, Pages 1-10

  Wu, Hailiang ^a   Cabral, Horacio ^a   Toh, Kazuko ^a   Mi, Peng ^b   Chen, Yi Chun ^a   Matsumoto, Yu ^a   Yamada, Naoki ^a   Liu, Xueying ^a   Kinoh, Hiroaki ^a   Miura, Yutaka ^a   Kano, Mitsunobu R ^c   Nishihara, Hiroshi ^d   Nishiyama, Nobuhiro ^b   Kataoka, Kazunori ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Chemotherapy; Cyclooxygenase 2; Drug delivery system; Metastatic niche; Oxaliplatin

Indexed keywords

CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; DIAGNOSIS; DISEASE CONTROL; HISTOLOGY; MICELLES; PATHOLOGY; PLATINUM COMPOUNDS; POLYMERS; TUMORS;

ANTICANCER ACTIVITIES; CYCLOOXYGENASE 2; DRUG DELIVERY SYSTEM; ENHANCED PERMEABILITY AND RETENTIONS; INTRAVENOUS INJECTIONS; METASTATIC NICHE; OXALIPLATIN; PLATINUM ANTICANCER DRUGS;

TARGETED DRUG DELIVERY;

(1,2 DIAMINOCYCLOHEXANE)PLATINUM; ANTINEOPLASTIC AGENT; NANOCARRIER; OXALIPLATIN; PLACEBO; PLATINUM DERIVATIVE; UNCLASSIFIED DRUG; ((1R,2R)-1,2-DIAMINOCYCLOHEXANE)PLATINUM(II); DRUG CARRIER; MICELLE; PLATINUM COMPLEX; POLYMER;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLUMINESCENCE; CANCER GROWTH; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG TARGETING; INFLAMMATION; LIVER METASTASIS; MICELLE; MICROMETASTASIS; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT; ADENOCARCINOMA; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; COLONIC NEOPLASMS; LIVER NEOPLASMS; NEOPLASM MICROMETASTASIS; PATHOLOGY; SECONDARY; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG CARRIERS; INFLAMMATION; LIVER NEOPLASMS; MICE, INBRED BALB C; MICELLES; NEOPLASM MICROMETASTASIS; ORGANOPLATINUM COMPOUNDS; POLYMERS;

EID: 84903844184     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.06.018     Document Type: Article

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