Responsiveness of hepatic and cerebral cytochrome P450 in rat offspring prenatally and lactationally exposed to a reconstituted PCB mixture

Environmental Toxicology

Volumn 29, Issue 8, 2014, Pages 856-866

  Bonfanti, Patrizia ^a   Comelli, Francesca ^a   Assi, Laura ^a   Casati, Lavinia ^b   Colciago, Alessandra ^b   Villa, Sara ^a   Santagostino, Angela ^a   Costa, Barbara ^a   Colombo, Anita ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Cytochrome P450; Lactation; PCB126; PCB138; PCB153; PCB180; Rat offspring

Indexed keywords

MIXTURES; POLYCHLORINATED BIPHENYLS; RATS;

CYTOCHROME P450; LACTATION; PCB126; PCB138; PCB153; PCB180;

ORGANIC POLLUTANTS;

3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A; CYTOCHROME P450 2B; DIOXIN; POLYCHLORINATED BIPHENYL;

BIOACCUMULATION; BIOTRANSFORMATION; BREASTFEEDING; CYTOCHROME; DOSE-RESPONSE RELATIONSHIP; LACTATION; PCB; POLLUTION EXPOSURE; RODENT; VULNERABILITY;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ARTICLE; BIOTRANSFORMATION; BREAST FEEDING; BREAST MILK; CONTROLLED STUDY; ENZYME INDUCTION; FEMALE; LACTATION; LIVER LEVEL; MILK; MOTHER CHILD RELATION; NONHUMAN; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; RAT; WEANING; WESTERN BLOTTING;

RATTUS;

CYTOCHROME P450; LACTATION; PCB126; PCB138; PCB153; PCB180; RAT OFFSPRING;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; ENVIRONMENTAL POLLUTANTS; FEMALE; ISOENZYMES; LACTATION; LIVER; MALE; MATERNAL EXPOSURE; MILK; OXIDATION-REDUCTION; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; TISSUE DISTRIBUTION;

EID: 84903820544     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21812     Document Type: Article

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