Responsiveness of cerebral and hepatic cytochrome P450s in rat offspring prenatally exposed to lindane

Toxicology and Applied Pharmacology

Volumn 231, Issue 1, 2008, Pages 10-16

  Johri, Ashu ^a   Yadav, Sanjay ^a   Dhawan, Alok ^a   Parmar, Devendra ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Brain; Cytochrome P450; Gestation; Lindane; Rat; Responsiveness

Indexed keywords

3 METHYLCHOLANTHRENE; BRAIN ENZYME; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; LINDANE; LIVER ENZYME; MESSENGER RNA; PHENOBARBITAL; XENOBIOTIC AGENT;

ARTICLE; BRAIN; ENZYME ACTIVITY; LIVER; PRENATAL EXPOSURE; PROGENY;

ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BRAIN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; INSECTICIDES; LINDANE; LIVER; MALE; METHYLCHOLANTHRENE; NEUROTOXICITY SYNDROMES; PHENOBARBITAL; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 48449100909     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.03.019     Document Type: Article

References (37)

1. Aarif E.M., and Huisingh D. Environmental xenoestrogens: short-term exposure of low doses of lindane, dieldrin, dibutyl phthalate, and diethylhexyl phthalate increases uterine weight in young female mice. Anal. Sci. 17 (2001) 1261
2. Abalis I.M., Elderfrawi M.E., and Elderfrawi A.T. High affinity stereospecific binding of cyclodiene insecticides and g-hexachlorocyclohexane to g-aminobutyric acid receptor of rat brain. Pestic. Biochem. Physiol. 24 (1985) 95-102
3. Agrawal A.K., and Shapiro B.H. Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital. J. Pharmacol. Exp. Ther. 279 (1996) 991-999
4. Agrawal A.K., and Shapiro B.H. Latent overexpression of hepatic CYP2C7 in adult male and female rats neonatally exposed to phenobarbital: a developmental profile of gender-dependent P450s. J. Pharmacol. Exp. Ther. 293 (2000) 1027-1033
5. Agrawal A.K., and Shapiro B.H. Neonatal phenobarbital imprints overexpression of cytochromes P450 with associated increase in tumorigenesis and reduced life span. FASEB J. 19 (2005) 470-472
6. Aks S.E., Krantz A., Hryhrczuk D.O., Wagner S., and Mock J. Acute accidental lindane ingestion in toddlers. Ann. Emerg. Med. 26 (1995) 647-651
7. Albertson T.E., Joy R.M., and Stark L.G. Facilitation of kindling in adult rats following neonatal exposure to lindane. Dev. Brain Res. 17 (1985) 263-266
8. Anderson L.M., Jones A.B., and Riggs C.W. Long-term (imprinting) effects of transplacental treatment of mice with 3-methylcholanthrene or beta-naphthoflavone on hepatic metabolism of 3-methylcholanthrene. Pharmacol. Toxicol. 69 (1991) 178-188
9. ATSDR. Agency for Toxic Substance and Disease Registry US Dept. of Health. Toxicological profile for alpha, beta, gamma and delta hexachlorocyclohexane-an update (1998)
10. ATSDR. Agency for Toxic Substance and Disease Registry US Dept. of Health. Toxicological profile for hexachlorocyclohexane (2005)
11. Bagley D.M., and Hayes J.R. Xenobiotic imprinting of the hepatic monooxygenase system. Effects of neonatal phenobarbital administration. Biochem. Pharmacol. 34 (1985) 1007-1014
12. Banerjee B.D., Zaidi S.S.A., Pasha S.T., Rawak D.S., Koner B.C., and Hussain Q.Z. Levels of HCH residues in human milk samples from Delhi, India. Bull. Environ. Contam. Toxicol. 59 (1997) 403-406
13. Baumann K., Angerer J., Heinrich R., and Lehnert G. Occupational exposure to hexachlorocyclohexane. I. Body burden of HCH-isomers. Int. Arch. Occup. Environ. Health 47 (1980) 119-127
14. Bloomquist J.R., Barlow R.L., Gillette J.S., Li W., and Kirby M.L. Selective effects of insecticides on nigrostriatal dopaminergic nerve pathways. Neurotoxicol. 23 4-5 (2002) 537-544
15. Chadwick R.W., Copeland M.F., Mole M.L., Nesnow S., and Cooke N. Comparative effect of pretreatment with phenobarbital, Aroclor 1254 and beta-naphthoflavone on the metabolism of lindane. Pestic. Biochem. Physiol. 15 (1981) 120-136
16. Chang T.K., Chan M.M., Holsmer S.L., Bandiera S.M., and Bellward G.D. Impact of tamoxifen on peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11, cytochrome P450 3A2 and steroid 5 alpha reductase. Biochem. Pharmacol. 51 (1996) 357-368
17. Dalsenter P.R., Faqi A.S., and Chahoud I. Serum testosterone and sexual behavior in rats after prenatal exposure to lindane. Bull. Environ. Contam. Toxicol. 59 (1997) 360-366
18. Dalsenter P.R., Faqi A.S., and Webb J. Reproductive toxicity and toxicokinetics of lindane in the male offspring of rats exposed during lactation. Hum. Exp. Toxicol. 16 (1997) 146-153
19. Gupta C., Sonawane B.R., Yaffe S.J., and Shapiro B.H. Phenobarbital exposure in utero: alternations in female reproductive function in rats. Science (Wash DC) 208 (1980) 508-510
20. Gupta C., Yaffe S.J., and Shapiro B.H. Prenatal exposure to phenobarbital permanently decreases testosterone and causes reproductive dysfunction. Science (Wash DC) 216 (1982) 640-642
21. Johri A., Dhawan A., Singh R.L., and Parmar D. Effect of prenatal exposure of deltamethrin on the ontogeny of xenobiotic metabolizing cytochrome P450s in the brain and liver of offsprings. Toxicol. Appl. Pharmacol. 214 (2006) 279-289
22. Johri A., Yadav S., Singh R.L., Dhawan A., Ali M., and Parmar D. Long lasting effects of prenatal exposure to deltamethrin on cerebral and hepatic cytochrome P450s and behavioral activity in rat offspring. Eur. J. Pharmacol. 544 (2006) 58-68
23. Johri A., Yadav S., Dhawan A., and Parmar D. Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane. Toxicol. Appl. Pharmacol. 225 (2007) 278-292
24. Johri A., Dhawan A., Singh R.L., and Parmar D. Persistence in alterations in the ontogeny of cerebral and hepatic cytochrome P450s following prenatal exposure to low doses of lindane. Toxicol. Sci. 101 2 (2008) 331-340
25. Jung D., Becher H., Edler L., Flesch-Janys D., Gurn P., Konietzko J., Manz A., and Päpke O. Elimination of beta-hexachlorocyclohexane in occupationally exposed persons. J. Toxicol. Environ. Health. 51 (1997) 23-34
26. Lamartinere C.A., and Pardo G.A. Altered activation/detoxication enzymology following neonatal diethylstilbestrol treatment. J. Biochem. Toxicol. 3 (1988) 87-103
27. Liu P.T., and Morgan D.P. Comparative toxicity and biotransformation of lindane in C57BL/6 and DBA/2 mice. Life Sci. 39 (1986) 1237-1244
28. Maranghi F., Rescia M., Macri C., Di Consiglio E., De Angelis G., and Testai E. Lindane may modulate the female reproductive development through the interaction with ER-β: an in vivo-in vitro approach. Chemico-Biol. Interact. 169 (2007) 1-14
29. Moorthy B. Persistent expression of 3-methylcholanthrene inducible cytochrome P450 1A in rat hepatic ad extrahepatic tissues. J. Pharmacol. Exp. Ther. 294 (2000) 313-322
30. Nair A., Mandapati R., and Dureja P. DDT and HCH load in mothers and their infants in Delhi, India. Bull. Environ. Contam. Toxicol. 56 (1996) 58-64
31. Parmar D., Yadav S., Dayal M., Johri A., Dhawan A., and Seth P.K. Effect of lindane on hepatic and brain cytochrome P450s and influence of P450 modulation in lindane induced neurotoxicity. Food Chem. Toxicol. 41 (2003) 1077-1087
32. Rivera S., Rosa R., Martínez E., Sunol C., Serrano M.T., and Vendrell M. Behavioral and monoaminergic changes after lindane exposure in developing rats. Neurotoxicol. Teratol. 20 (1998) 155-160
33. Serrano M.J., Vendrell M., Rivera S., Serratosa J., and Rodrguez-Farre E. Effect of lindane on the myelination process in the rat. Neurotoxicol. Teratol. 12 (1990) 577-583
34. Sunol C., Tusell J.M., Gelpi E., and Rodriguez-Farre E. GABAergic modulation of lindane (gamma-hexachlorocyclohexane)-induced seizures. Toxicol. Appl. Pharmacol. 100 (1989) 1-8
35. Vale C., Pomes A., Rodriguez-Farre E., and Sunol C. Allosteric interactions between gamma-aminobutyric acid, benzodiazepine and picrotoxinin binding sites in primary cultures of cerebellar granule cells. Differential effects induced by gamma- and delta-hexachlorocyclohexane. Eur. J. Pharmacol. 319 3 (1997) 343-353
36. Wani J.H., Agrawal A.K., and Shapiro B.H. Neonatal PB induced persistent alterations in plasme testosterone profiles and testicular function. Toxicol. Appl. Pharmacol. 137 (1996) 295-300
37. Zangar R.C., Springer D.L., McCrary J.A., Novak R.F., Primiano T., and Buhler D.R. Changes in adult metabolism of aflatoxin B1 in rats neonatally exposed to diethylstilbestrol. Alterations in alpha-class glutathione S-transferases. Carcinogenesis 13 (1992) 2375-2379