In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: Toxicity in pups dependent on the Cyp1a2 and Ahr genotypes

Toxicological Sciences

Volumn 119, Issue 1, 2011, Pages 189-208

  Curran, Christine P ^a,b   Vorhees, Charles V ^a   Williams, Michael T ^a   Genter, Mary Beth ^a   Miller, Marian L ^a   Nebert, Daniel W ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b NORTHERN KENTUCKY UNIVERSITY   (United States)

Author keywords

Aryl hydrocarbon receptor; Cytochrome P450 1A2; Developmental toxicity; Gas chromatography electron capture detection; Immunosuppression; In utero exposure; PCB congeners; PCB mixture

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A2; POLYCHLORINATED BIPHENYL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIRTH WEIGHT; BREAST MILK; CATERING SERVICE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DETOXIFICATION; EMBRYO; FEEDING; FEMALE; GASTROINTESTINAL TRACT; GENOTYPE; GESTATIONAL AGE; GROWTH; KNOCKOUT MOUSE; LACTATION; LIVER HYPERTROPHY; MALE; MOTHER; MOUSE; NONHUMAN; PERINATAL DRUG EXPOSURE; PERINATAL PERIOD; PUP (RODENT); RECEPTOR AFFINITY; SPLEEN; TERATOGENICITY; THYMUS ATROPHY; TISSUE; WILD TYPE;

EID: 78650577848     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq314     Document Type: Article

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