-
1
-
-
58149307496
-
Combinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapy
-
Baxevanis C.N., Perez S.A., Papamichail M. Combinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapy. Cancer Immunol Immunother 2009, 58:317-324.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 317-324
-
-
Baxevanis, C.N.1
Perez, S.A.2
Papamichail, M.3
-
2
-
-
84865692672
-
The use of biologics in cancer therapy
-
Oncology suppl
-
Boyle R.M. The use of biologics in cancer therapy. US Pharm 2010, 35(3):4-7. Oncology suppl.
-
(2010)
US Pharm
, vol.35
, Issue.3
, pp. 4-7
-
-
Boyle, R.M.1
-
3
-
-
39849099958
-
Biological treatment for liver tumor and new potential biomarkers
-
Chiriva-Internati M., Grizzi F., Wachtel M.S., et al. Biological treatment for liver tumor and new potential biomarkers. Dig Dis Sci 2008, 53:836-843.
-
(2008)
Dig Dis Sci
, vol.53
, pp. 836-843
-
-
Chiriva-Internati, M.1
Grizzi, F.2
Wachtel, M.S.3
-
4
-
-
57649177401
-
Trastuzumab cardiotoxicity: Biological hypotheses and clinical open issues
-
Brennan and Bria E., Cuppone F., Milella M., Verma S., Carlini P., Nistico C., et al. Trastuzumab cardiotoxicity: Biological hypotheses and clinical open issues. Expert Opin Biol Ther 2008, 8:1963-1971.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 1963-1971
-
-
Brennan, B.E.1
Cuppone, F.2
Milella, M.3
Verma, S.4
Carlini, P.5
Nistico, C.6
-
6
-
-
85031250263
-
-
ICH Topic S6. Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals. Current Step 4 version Dated July 1997.
-
ICH Topic S6. Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals. Current Step 4 version Dated July 1997.
-
-
-
-
7
-
-
84903798913
-
-
ICH Harmonized Tripartite Guideline. Addendum to ICH S6: Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals, S6(R1). Current Step 2 version Dated October 29
-
ICH Harmonized Tripartite Guideline. Addendum to ICH S6: Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals, S6(R1). Current Step 2 version Dated October 29, 2009.
-
(2009)
-
-
-
8
-
-
85031247389
-
-
ICH Topic S9. Nonclinical Evaluation for Anticancer Pharmaceuticals. Current Step 4 version Dated March 2010.
-
ICH Topic S9. Nonclinical Evaluation for Anticancer Pharmaceuticals. Current Step 4 version Dated March 2010.
-
-
-
-
9
-
-
78549259732
-
ICH Guidances: Inception, revision, and implementation for drug development
-
Wang T., Jacobson-Kram D., Pilaro A.M., Lapadula D., Jacobs A., Brown P., et al. ICH Guidances: Inception, revision, and implementation for drug development. Tox Sci 2010, 118(2):356-357.
-
(2010)
Tox Sci
, vol.118
, Issue.2
, pp. 356-357
-
-
Wang, T.1
Jacobson-Kram, D.2
Pilaro, A.M.3
Lapadula, D.4
Jacobs, A.5
Brown, P.6
-
10
-
-
85031257928
-
Introduction to biotech drugs
-
O'Conner A. Introduction to biotech drugs. Reg Rapport 2009, 6(1):4-7.
-
(2009)
Reg Rapport
, vol.6
, Issue.1
, pp. 4-7
-
-
O'Conner, A.1
-
11
-
-
77957575471
-
Practical approaches to dose selection for first-in-human clinical trials with novel biopharmaceuticals
-
Tibbitts J., Cavagnaro J.A., Haller C.A., Marafino B., Andrews P.A., Sullivan J.T. Practical approaches to dose selection for first-in-human clinical trials with novel biopharmaceuticals. Reg Tox Pharmacol 2010, 58:243-251.
-
(2010)
Reg Tox Pharmacol
, vol.58
, pp. 243-251
-
-
Tibbitts, J.1
Cavagnaro, J.A.2
Haller, C.A.3
Marafino, B.4
Andrews, P.A.5
Sullivan, J.T.6
-
12
-
-
49649101856
-
Species selection considerations for preclinical toxicology studies for biotherapeutics
-
Bussiere J. Species selection considerations for preclinical toxicology studies for biotherapeutics. Expert Opin Drug Metab Toxicol 2008, 4(7):871-877.
-
(2008)
Expert Opin Drug Metab Toxicol
, vol.4
, Issue.7
, pp. 871-877
-
-
Bussiere, J.1
-
13
-
-
0033921144
-
Preclinical development of keliximab, a primatized anti-CD4 monoclonal antibody, in human CD4 transgenic mice: Characterization of the model and safety studies
-
Bugelski P.J., Herzyk D.J., Rehm S., Harmsen A.G., Gore E.V., Williams D.M., et al. Preclinical development of keliximab, a primatized anti-CD4 monoclonal antibody, in human CD4 transgenic mice: Characterization of the model and safety studies. Hum Exp Toxicol 2000, 19(4):230-243.
-
(2000)
Hum Exp Toxicol
, vol.19
, Issue.4
, pp. 230-243
-
-
Bugelski, P.J.1
Herzyk, D.J.2
Rehm, S.3
Harmsen, A.G.4
Gore, E.V.5
Williams, D.M.6
-
14
-
-
34447091994
-
Preclinical and clinical safety of monoclonal antibodies
-
Tabrizi M.A., Roskos L.K. Preclinical and clinical safety of monoclonal antibodies. Drug Disc Today 2007, 12(13-14):540-547.
-
(2007)
Drug Disc Today
, vol.12
, Issue.13-14
, pp. 540-547
-
-
Tabrizi, M.A.1
Roskos, L.K.2
-
15
-
-
41149095997
-
Preclinical development of therapeutic biologics
-
Baumann A. Preclinical development of therapeutic biologics. Expert Opin Drug Discov 2008, 8(3):289-297.
-
(2008)
Expert Opin Drug Discov
, vol.8
, Issue.3
, pp. 289-297
-
-
Baumann, A.1
-
16
-
-
14444267319
-
Regulatory considerations for preclinical development of anticancer drugs
-
DeGeorge J.J., Ahn C.-H., Andrews P.A., Brower M.E., Giorgio D.W., Goheer M.A., et al. Regulatory considerations for preclinical development of anticancer drugs. Cancer Chemother Pharmacol 1998, 41:173-185.
-
(1998)
Cancer Chemother Pharmacol
, vol.41
, pp. 173-185
-
-
DeGeorge, J.J.1
Ahn, C.-H.2
Andrews, P.A.3
Brower, M.E.4
Giorgio, D.W.5
Goheer, M.A.6
-
17
-
-
54249121649
-
Safety issues specific to clinical development of protein therapeutics
-
Haller C.A., Cosenza M.E., Sullivan J.T. Safety issues specific to clinical development of protein therapeutics. Clin Pharmacol Therap 2008, 84(5):624-627.
-
(2008)
Clin Pharmacol Therap
, vol.84
, Issue.5
, pp. 624-627
-
-
Haller, C.A.1
Cosenza, M.E.2
Sullivan, J.T.3
-
18
-
-
84862759363
-
ADME of biologics-what have we learned from small molecules?
-
Prueksaritanont T., Tang C. ADME of biologics-what have we learned from small molecules?. AAPS J 2012, 14(3):410-419.
-
(2012)
AAPS J
, vol.14
, Issue.3
, pp. 410-419
-
-
Prueksaritanont, T.1
Tang, C.2
-
19
-
-
84856270574
-
The enhanced pre- and postnatal study for nonhuman primates: Update and perspectives
-
Weinbauer G.F., Fuchs A., Niehaus M., Luetjens C.M. The enhanced pre- and postnatal study for nonhuman primates: Update and perspectives. Birth Defects Res C Embryo Today 2011, 93(4):324-333.
-
(2011)
Birth Defects Res C Embryo Today
, vol.93
, Issue.4
, pp. 324-333
-
-
Weinbauer, G.F.1
Fuchs, A.2
Niehaus, M.3
Luetjens, C.M.4
-
20
-
-
85031268392
-
-
ICH Topic S1a. Guideline on the Need for Carcinogenicity Studies of Pharmaceuticals. Current Step 4 version Dated Nov 1995.
-
ICH Topic S1a. Guideline on the Need for Carcinogenicity Studies of Pharmaceuticals. Current Step 4 version Dated Nov 1995.
-
-
-
-
21
-
-
84865141761
-
Glycoengineering approach to half-life extension of recombinant biotherapeutics
-
Chen C., Constantinou A., Chester K.A., Vyas B., Canis K., Haslam S.M., et al. Glycoengineering approach to half-life extension of recombinant biotherapeutics. Bioconjug Chem 2012, 23(8):1524-1533.
-
(2012)
Bioconjug Chem
, vol.23
, Issue.8
, pp. 1524-1533
-
-
Chen, C.1
Constantinou, A.2
Chester, K.A.3
Vyas, B.4
Canis, K.5
Haslam, S.M.6
-
22
-
-
84869115847
-
Challenges and opportunities in absorption, distribution, metabolism, and excretion studies of therapeutic biologics
-
Xu X., Vugmeyster Y. Challenges and opportunities in absorption, distribution, metabolism, and excretion studies of therapeutic biologics. AAPS J 2012, 14(4):781-791.
-
(2012)
AAPS J
, vol.14
, Issue.4
, pp. 781-791
-
-
Xu, X.1
Vugmeyster, Y.2
-
23
-
-
84866736720
-
Anti-neuropilin-1 (MNRP1685A): Unexpected pharmacokinetic differences across species, from preclinical models to humans
-
Xin Y., Bai S., Damico-Beyer L.A., Jin D., Liang W.-C., Wu Y., et al. Anti-neuropilin-1 (MNRP1685A): Unexpected pharmacokinetic differences across species, from preclinical models to humans. Pharmac Res 2012, 29(9):2512-2521.
-
(2012)
Pharmac Res
, vol.29
, Issue.9
, pp. 2512-2521
-
-
Xin, Y.1
Bai, S.2
Damico-Beyer, L.A.3
Jin, D.4
Liang, W.-C.5
Wu, Y.6
-
24
-
-
79960091033
-
Highly specific off-target binding identified and eliminated during the humanization of an antibody against FGF receptor 4
-
Bumbaca D., Wong A., Drake E., Reyes A.E., Lin B.C., Stephan J.P., et al. Highly specific off-target binding identified and eliminated during the humanization of an antibody against FGF receptor 4. MAbs 2011, 3(4):376-386.
-
(2011)
MAbs
, vol.3
, Issue.4
, pp. 376-386
-
-
Bumbaca, D.1
Wong, A.2
Drake, E.3
Reyes, A.E.4
Lin, B.C.5
Stephan, J.P.6
-
25
-
-
77955331645
-
Design of next-generation protein therapeutics
-
Caravella J., Lugovskoy A. Design of next-generation protein therapeutics. Curr Opin Chem Biol 2010, 14:520-528.
-
(2010)
Curr Opin Chem Biol
, vol.14
, pp. 520-528
-
-
Caravella, J.1
Lugovskoy, A.2
-
26
-
-
77349117260
-
Evaluation of a generic immunoassay with drug tolerance to detect immune complexes in serum samples from cynomolgus monkeys after administration of human antibodies
-
Stubenrauch K., Wessels U., Essig U., Vogel R., Schleypen J. Evaluation of a generic immunoassay with drug tolerance to detect immune complexes in serum samples from cynomolgus monkeys after administration of human antibodies. J Pharmaceut Biomed Analysis 2010, 52(2):249-254.
-
(2010)
J Pharmaceut Biomed Analysis
, vol.52
, Issue.2
, pp. 249-254
-
-
Stubenrauch, K.1
Wessels, U.2
Essig, U.3
Vogel, R.4
Schleypen, J.5
-
27
-
-
81355133688
-
Clinical trials in the era of personalized oncology
-
Maitland M.L., Schilsky R.L. Clinical trials in the era of personalized oncology. Cancer J Clin 2011, 61(6):365-381.
-
(2011)
Cancer J Clin
, vol.61
, Issue.6
, pp. 365-381
-
-
Maitland, M.L.1
Schilsky, R.L.2
-
28
-
-
33746879918
-
Drug development in oncology: Classical cytotoxics and molecularly targeted agents
-
Kummar S., Gutierrez M., Doroshow J.H., Murgo A.J. Drug development in oncology: Classical cytotoxics and molecularly targeted agents. Br J Clin Pharmacol 2006, 62(1):15-26.
-
(2006)
Br J Clin Pharmacol
, vol.62
, Issue.1
, pp. 15-26
-
-
Kummar, S.1
Gutierrez, M.2
Doroshow, J.H.3
Murgo, A.J.4
-
29
-
-
1842458410
-
Development and use of biomarkers in oncology drug development
-
Floyd E., McShane T.M. Development and use of biomarkers in oncology drug development. Toxic Path 2004, 32(1):106-115.
-
(2004)
Toxic Path
, vol.32
, Issue.1
, pp. 106-115
-
-
Floyd, E.1
McShane, T.M.2
-
30
-
-
59449094823
-
Biomarkers in oncology drug development
-
Hodgson D.R., Whittaker R.D., Herath A., Amakye D., Clack G. Biomarkers in oncology drug development. Mol Oncol 2009, 3:24-32.
-
(2009)
Mol Oncol
, vol.3
, pp. 24-32
-
-
Hodgson, D.R.1
Whittaker, R.D.2
Herath, A.3
Amakye, D.4
Clack, G.5
-
31
-
-
84857039823
-
Qualification of imaging biomarkers for oncology drug development
-
Waterton J.C., Pylkkanen L. Qualification of imaging biomarkers for oncology drug development. Eur J Cancer 2012, 48:409-415.
-
(2012)
Eur J Cancer
, vol.48
, pp. 409-415
-
-
Waterton, J.C.1
Pylkkanen, L.2
-
33
-
-
75349083715
-
Harnessing the energy: Development of radioimmunotherapy for patients with non-Hodgkin's lymphoma
-
Gregory S.A., Hohloch K., Gisselbrecht C., et al. Harnessing the energy: Development of radioimmunotherapy for patients with non-Hodgkin's lymphoma. Oncologist 2009, 14(Suppl. 2):4-16.
-
(2009)
Oncologist
, vol.14
, Issue.SUPPL. 2
, pp. 4-16
-
-
Gregory, S.A.1
Hohloch, K.2
Gisselbrecht, C.3
-
34
-
-
33746836894
-
Targeted therapy of cancer: New prospects for antibodies and immunoconjugates
-
Sharkey R.M., Goldenberg D.M. Targeted therapy of cancer: New prospects for antibodies and immunoconjugates. CA Cancer J Clin 2006, 56:226-243.
-
(2006)
CA Cancer J Clin
, vol.56
, pp. 226-243
-
-
Sharkey, R.M.1
Goldenberg, D.M.2
-
35
-
-
34249821912
-
Rituximab therapy in malignant lymphoma
-
Coiffier B. Rituximab therapy in malignant lymphoma. Oncogene 2007, 26:3603-3613.
-
(2007)
Oncogene
, vol.26
, pp. 3603-3613
-
-
Coiffier, B.1
-
36
-
-
58549115713
-
Safety of biologic therapy in rheumatoidarthritis and other autoimmune diseases: Focus on rituximab
-
Fleischmann R.M. Safety of biologic therapy in rheumatoidarthritis and other autoimmune diseases: Focus on rituximab. Semin Arthritis Rheum 2009, 38:265-280.
-
(2009)
Semin Arthritis Rheum
, vol.38
, pp. 265-280
-
-
Fleischmann, R.M.1
-
37
-
-
27544508559
-
Tolerability and safety of rituximab (MabThera)
-
Kimby E. Tolerability and safety of rituximab (MabThera). Cancer Treat Rev 2005, 31:456-473.
-
(2005)
Cancer Treat Rev
, vol.31
, pp. 456-473
-
-
Kimby, E.1
-
38
-
-
67749087489
-
The late adverse events of rituximab therapy-rare but there!
-
Ram R., Ben-Bassat I., Shpilberg O., Polliack A., Raanani P. The late adverse events of rituximab therapy-rare but there!. Leuk Lymphoma 2009, 50:1083-1095.
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 1083-1095
-
-
Ram, R.1
Ben-Bassat, I.2
Shpilberg, O.3
Polliack, A.4
Raanani, P.5
-
39
-
-
0028057250
-
Depletion of B cells in vivo by a chimeric mousehuman monoclonal antibody to CD20
-
Reff M.E., Carner K., Chambers K.S., Chinn P.C., Leonard J.E., Raab R., et al. Depletion of B cells in vivo by a chimeric mousehuman monoclonal antibody to CD20. Blood 1994, 83:435-445.
-
(1994)
Blood
, vol.83
, pp. 435-445
-
-
Reff, M.E.1
Carner, K.2
Chambers, K.S.3
Chinn, P.C.4
Leonard, J.E.5
Raab, R.6
-
40
-
-
77951829072
-
Veltuzumab (humanized anti-CD20 monoclonal antibody): Characterization, current clinical results, and future prospects
-
Goldenberg D.M., Morschhauser F., Wegener W.A. Veltuzumab (humanized anti-CD20 monoclonal antibody): Characterization, current clinical results, and future prospects. Leuk Lymphoma 2010, 51:747-755.
-
(2010)
Leuk Lymphoma
, vol.51
, pp. 747-755
-
-
Goldenberg, D.M.1
Morschhauser, F.2
Wegener, W.A.3
-
41
-
-
70349733184
-
Effect of B-cell depletion on viral replication andclinical outcome of simian immunodeficiency virus infection in anatural host
-
Gaufin T., Pattison M., Gautam R., Stoulig C., Dufour J., MacFarland J., et al. Effect of B-cell depletion on viral replication andclinical outcome of simian immunodeficiency virus infection in anatural host. J Virol 2009, 83:10347-10357.
-
(2009)
J Virol
, vol.83
, pp. 10347-10357
-
-
Gaufin, T.1
Pattison, M.2
Gautam, R.3
Stoulig, C.4
Dufour, J.5
MacFarland, J.6
-
42
-
-
84860854354
-
Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: Cell surface targets
-
Bugelski P.J., Martin P.L. Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: Cell surface targets. Br J Pharmacol 2012, 166:823-846.
-
(2012)
Br J Pharmacol
, vol.166
, pp. 823-846
-
-
Bugelski, P.J.1
Martin, P.L.2
-
43
-
-
84903803811
-
-
European Medicines Agency
-
European Medicines Agency Scientific Discussion on Rituximab http://www.ema.europa.eu/%20docs/en_GB/document_library/EPAR_-_Scientific_Discussion/human/000165/WC500025817.pdf.
-
Scientific Discussion on Rituximab
-
-
-
44
-
-
78650551562
-
Developmental immunotoxicology assessment ofrituximab in cynomolgus monkeys
-
Vaidyanathan A., McKeever K., Anand B., Eppler S., Weinbauer G.F., Beyer J.C. Developmental immunotoxicology assessment ofrituximab in cynomolgus monkeys. Toxicol Sci 2011, 119:116-125.
-
(2011)
Toxicol Sci
, vol.119
, pp. 116-125
-
-
Vaidyanathan, A.1
McKeever, K.2
Anand, B.3
Eppler, S.4
Weinbauer, G.F.5
Beyer, J.C.6
-
45
-
-
85031240346
-
-
Rituxan USPI http://www.gene.com/gene/products/information/pdf/rituxan-prescribing.pdf.
-
Rituxan USPI
-
-
-
46
-
-
84903798905
-
-
European Medicines Agency
-
European Medicines Agency Scientific Discussion on Avastin http://www.ema.europa.eu/%20docs/en_GB/document_library/EPAR_-_Scientific_Discussion/human/000582/WC500029262.pdf.
-
Scientific Discussion on Avastin
-
-
-
47
-
-
0026708632
-
The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies
-
Kim K.J., Li B., Houck K., Winer J., Ferrara N. The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 1992, 7(1):53-64.
-
(1992)
Growth Factors
, vol.7
, Issue.1
, pp. 53-64
-
-
Kim, K.J.1
Li, B.2
Houck, K.3
Winer, J.4
Ferrara, N.5
-
48
-
-
0035704913
-
The role of vascular endothelial growth factor in angiogenesis
-
Ferrara N., Gerber H.P. The role of vascular endothelial growth factor in angiogenesis. Acta Haematol 2001, 106(4):148-156.
-
(2001)
Acta Haematol
, vol.106
, Issue.4
, pp. 148-156
-
-
Ferrara, N.1
Gerber, H.P.2
-
49
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara N., Gerber H.P., LeCouter J. The biology of VEGF and its receptors. Nat Med 2003, 9(6):669-676.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
LeCouter, J.3
-
50
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara N., Carver-Moore K., Chen H., Dowd M., Lu L., O'Shea K.S., et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996, 380(6573):439-442.
-
(1996)
Nature
, vol.380
, Issue.6573
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
-
51
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P., Ferreira V., Breier G., Pollefeyt S., Kieckens L., Gertsenstein M., et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996, 380(6573):435-439.
-
(1996)
Nature
, vol.380
, Issue.6573
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
-
52
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara N., Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 1997, 18(1):4-25.
-
(1997)
Endocr Rev
, vol.18
, Issue.1
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
53
-
-
4244078727
-
VEGF receptor signal transduction
-
Matsumoto T., Claesson-Welsh L. VEGF receptor signal transduction. Sci STKE 2001, 2001(112):RE21.
-
(2001)
Sci STKE
, vol.2001
, Issue.112
-
-
Matsumoto, T.1
Claesson-Welsh, L.2
-
54
-
-
0029949160
-
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
-
Yuan F., Chen Y., Dellian M., Safabakhsh N., Ferrara N., Jain R.K. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci U S A 1996, 93(25):14765-14770.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.25
, pp. 14765-14770
-
-
Yuan, F.1
Chen, Y.2
Dellian, M.3
Safabakhsh, N.4
Ferrara, N.5
Jain, R.K.6
-
55
-
-
0032557564
-
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
-
1998
-
Gerber H.P., Dixit V., Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 1998, 273(21):13313-13316. 1998.
-
(1998)
J Biol Chem
, vol.273
, Issue.21
, pp. 13313-13316
-
-
Gerber, H.P.1
Dixit, V.2
Ferrara, N.3
-
56
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
-
Gerber H.P., McMurtrey A., Kowalski J., Yan M., Keyt B.A., Dixit V., et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 1998, 273(46):30336-30343.
-
(1998)
J Biol Chem
, vol.273
, Issue.46
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Yan, M.4
Keyt, B.A.5
Dixit, V.6
-
57
-
-
0032952010
-
Selective ablation of immature blood vessels in established humantumors follows vascular endothelial growth factor withdrawal
-
Benjamin L.E., Golijanin D., Itin A., Pode D., Keshet E. Selective ablation of immature blood vessels in established humantumors follows vascular endothelial growth factor withdrawal. J Clin Invest 1999, 103(2):159-165.
-
(1999)
J Clin Invest
, vol.103
, Issue.2
, pp. 159-165
-
-
Benjamin, L.E.1
Golijanin, D.2
Itin, A.3
Pode, D.4
Keshet, E.5
-
58
-
-
0027217832
-
Vascular endothelial growth factor induces EDRF-dependent relaxation incoronary arteries
-
Ku D.D., Zaleski J.K., Liu S., Brock T.A. Vascular endothelial growth factor induces EDRF-dependent relaxation incoronary arteries. Am J Physiol 1993, 265(2 Pt 2):H586-H592.
-
(1993)
Am J Physiol
, vol.265
, Issue.2 PT 2
-
-
Ku, D.D.1
Zaleski, J.K.2
Liu, S.3
Brock, T.A.4
-
59
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak H.F., Brown L.F., Detmar M., Dvorak A.M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995, 146(5):1029-1039.
-
(1995)
Am J Pathol
, vol.146
, Issue.5
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
60
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger D.R., Galli S.J., Dvorak A.M., Perruzzi C.A., Harvey V.S., Dvorak H.F. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983, 219(4587):983-985.
-
(1983)
Science
, vol.219
, Issue.4587
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
61
-
-
0025688912
-
Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration
-
Clauss M., Gerlach M., Gerlach H., Brett J., Wang F., Familletti P.C., et al. Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990, 172(6):1535-1545.
-
(1990)
J Exp Med
, vol.172
, Issue.6
, pp. 1535-1545
-
-
Clauss, M.1
Gerlach, M.2
Gerlach, H.3
Brett, J.4
Wang, F.5
Familletti, P.C.6
-
62
-
-
0029842830
-
Production of vascular endothelial growth factor by human tumorsinhibits the functional maturation of dendritic cells
-
Gabrilovich D.I., Chen H.L., Girgis K.R., Cunningham H.T., Meny G.M., Nadaf S., et al. Production of vascular endothelial growth factor by human tumorsinhibits the functional maturation of dendritic cells. Nat Med 1996, 2(10):1096-1103.
-
(1996)
Nat Med
, vol.2
, Issue.10
, pp. 1096-1103
-
-
Gabrilovich, D.I.1
Chen, H.L.2
Girgis, K.R.3
Cunningham, H.T.4
Meny, G.M.5
Nadaf, S.6
-
63
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta L.G., Chen H., O'Connor S.J., Chisholm V., Meng Y.G., Krummen L., et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997, 57(20):4593-4599.
-
(1997)
Cancer Res
, vol.57
, Issue.20
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
Chisholm, V.4
Meng, Y.G.5
Krummen, L.6
-
64
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim K.J., Li B., Winer J., Armanini M., Gillett N., Phillips H.S., et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993, 362(6423):841-844.
-
(1993)
Nature
, vol.362
, Issue.6423
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
-
65
-
-
0029816983
-
Complete inhibition of angiogenesis and growth of microtumors by antivascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy
-
Borgstrom P., Hillan K.J., Sriramarao P., Ferrara N. Complete inhibition of angiogenesis and growth of microtumors by antivascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res 1996, 56(17):4032-4039.
-
(1996)
Cancer Res
, vol.56
, Issue.17
, pp. 4032-4039
-
-
Borgstrom, P.1
Hillan, K.J.2
Sriramarao, P.3
Ferrara, N.4
-
66
-
-
0031719516
-
Role of vascular endothelial growth factor in ovariancancer: Inhibition of ascites formation by immunoneutralization
-
Mesiano S., Ferrara N., Jaffe R.B. Role of vascular endothelial growth factor in ovariancancer: Inhibition of ascites formation by immunoneutralization. Am J Pathol 1998, 153(4):1249-1256.
-
(1998)
Am J Pathol
, vol.153
, Issue.4
, pp. 1249-1256
-
-
Mesiano, S.1
Ferrara, N.2
Jaffe, R.B.3
-
67
-
-
0031898292
-
Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo
-
Borgstrom P., Bourdon M.A., Hillan K.J., Sriramarao P., Ferrara N. Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo. Prostate 1998, 35(1):1-10.
-
(1998)
Prostate
, vol.35
, Issue.1
, pp. 1-10
-
-
Borgstrom, P.1
Bourdon, M.A.2
Hillan, K.J.3
Sriramarao, P.4
Ferrara, N.5
-
68
-
-
0028935608
-
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
-
Warren R.S., Yuan H., Matli M.R., Gillett N.A., Ferrara N. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin Invest 1995, 95(4):1789-1797.
-
(1995)
J Clin Invest
, vol.95
, Issue.4
, pp. 1789-1797
-
-
Warren, R.S.1
Yuan, H.2
Matli, M.R.3
Gillett, N.A.4
Ferrara, N.5
-
69
-
-
0034894341
-
Combination antiangiogenic therapy: Increased efficacy in a murine model of Wilms tumor
-
Soffer S.Z., Moore J.T., Kim E., Huang J., Yokoi A., Manley C., et al. Combination antiangiogenic therapy: Increased efficacy in a murine model of Wilms tumor. J Pediatr Surg 2001, 36(8):1177-1181.
-
(2001)
J Pediatr Surg
, vol.36
, Issue.8
, pp. 1177-1181
-
-
Soffer, S.Z.1
Moore, J.T.2
Kim, E.3
Huang, J.4
Yokoi, A.5
Manley, C.6
-
70
-
-
0037370294
-
Anti-VEGF antibody in experimental hepatoblastoma: Suppression of tumor growth and altered angiogenesis
-
McCrudden K.W., Hopkins B., Frischer J., Novikov A., Huang J., Kadenhe A., et al. Anti-VEGF antibody in experimental hepatoblastoma: Suppression of tumor growth and altered angiogenesis. J Pediatr Surg 2003, 38(3):308-314.
-
(2003)
J Pediatr Surg
, vol.38
, Issue.3
, pp. 308-314
-
-
McCrudden, K.W.1
Hopkins, B.2
Frischer, J.3
Novikov, A.4
Huang, J.5
Kadenhe, A.6
-
71
-
-
0035870297
-
The antiangiogenic property of docetaxel is synergistic with arecombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
-
Sweeney C.J., Miller K.D., Sissons S.E., Nozaki S., Heilman D.K., Shen J., et al. The antiangiogenic property of docetaxel is synergistic with arecombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 2001, 61(8):3369-3372.
-
(2001)
Cancer Res
, vol.61
, Issue.8
, pp. 3369-3372
-
-
Sweeney, C.J.1
Miller, K.D.2
Sissons, S.E.3
Nozaki, S.4
Heilman, D.K.5
Shen, J.6
-
72
-
-
0038501002
-
Evaluation of vascular endothelial growth factor blockade and matrixmetalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer
-
discussion 227-8
-
Hotz H.G., Hines O.J., Hotz B., Foitzik T., Buhr H.J., Reber H.A. Evaluation of vascular endothelial growth factor blockade and matrixmetalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer. J Gastrointest Surg 2003, 7(2):220-227. discussion 227-8.
-
(2003)
J Gastrointest Surg
, vol.7
, Issue.2
, pp. 220-227
-
-
Hotz, H.G.1
Hines, O.J.2
Hotz, B.3
Foitzik, T.4
Buhr, H.J.5
Reber, H.A.6
-
73
-
-
0034306974
-
Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
-
Lee C.G., Heijn M., di Tomaso E., Griffon-Etienne G., Ancukiewicz M., Koike C., et al. Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res 2000, 60(19):5565-5570.
-
(2000)
Cancer Res
, vol.60
, Issue.19
, pp. 5565-5570
-
-
Lee, C.G.1
Heijn, M.2
di Tomaso, E.3
Griffon-Etienne, G.4
Ancukiewicz, M.5
Koike, C.6
-
74
-
-
0036840759
-
Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer
-
Hu L., Hofmann J., Zaloudek C., Ferrara N., Hamilton T., Jaffe R.B. Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer. Am J Pathol 2002, 161(5):1917-1924.
-
(2002)
Am J Pathol
, vol.161
, Issue.5
, pp. 1917-1924
-
-
Hu, L.1
Hofmann, J.2
Zaloudek, C.3
Ferrara, N.4
Hamilton, T.5
Jaffe, R.B.6
-
75
-
-
0036191974
-
Distinct response of experimental neuroblastoma to combination antiangiogenic strategies
-
Kim E.S., Soffer S.Z., Huang J., McCrudden K.W., Yokoi A., Manley C.A., et al. Distinct response of experimental neuroblastoma to combination antiangiogenic strategies. J Pediatr Surg 2002, 37(3):518-522.
-
(2002)
J Pediatr Surg
, vol.37
, Issue.3
, pp. 518-522
-
-
Kim, E.S.1
Soffer, S.Z.2
Huang, J.3
McCrudden, K.W.4
Yokoi, A.5
Manley, C.A.6
-
76
-
-
0029888871
-
Cloning and mRNA expression of vascular endothelial growth factor in ischemic retinas of Macaca fascicularis
-
Shima D.T., Gougos A., Miller J.W., Tolentino M., Robinson G., Adamis A.P., et al. Cloning and mRNA expression of vascular endothelial growth factor in ischemic retinas of Macaca fascicularis. Invest Ophthalmol Vis Sci 1996, 37(7):1334-1340.
-
(1996)
Invest Ophthalmol Vis Sci
, vol.37
, Issue.7
, pp. 1334-1340
-
-
Shima, D.T.1
Gougos, A.2
Miller, J.W.3
Tolentino, M.4
Robinson, G.5
Adamis, A.P.6
-
77
-
-
0032979775
-
Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody
-
Ryan A.M., Eppler D.B., Hagler K.E., Bruner R.H., Thomford P.J., Hall R.L., et al. Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody. Toxicol Pathol 1999, 27(1):78-86.
-
(1999)
Toxicol Pathol
, vol.27
, Issue.1
, pp. 78-86
-
-
Ryan, A.M.1
Eppler, D.B.2
Hagler, K.E.3
Bruner, R.H.4
Thomford, P.J.5
Hall, R.L.6
-
78
-
-
0032470748
-
Normoxic wound fluid contains high levels of vascular endothelial growth factor
-
Howdieshell T.R., Riegner C., Gupta V., Callaway D., Grembowicz K., Sathyanarayana, et al. Normoxic wound fluid contains high levels of vascular endothelial growth factor. Ann Surg 1998, 228(5):707-715.
-
(1998)
Ann Surg
, vol.228
, Issue.5
, pp. 707-715
-
-
Howdieshell, T.R.1
Riegner, C.2
Gupta, V.3
Callaway, D.4
Grembowicz, K.5
Sathyanarayana6
-
79
-
-
0031779927
-
Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing
-
Nissen N.N., Polverini P.J., Koch A.E., Volin M.V., Gamelli R.L., DiPietro L.A. Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol 1998, 152(6):1445-1452.
-
(1998)
Am J Pathol
, vol.152
, Issue.6
, pp. 1445-1452
-
-
Nissen, N.N.1
Polverini, P.J.2
Koch, A.E.3
Volin, M.V.4
Gamelli, R.L.5
DiPietro, L.A.6
-
81
-
-
85031254010
-
-
Health Canada
-
Health Canada Product monograph for Herceptin http://rochecanada.com/fmfiles/%20re7234008/%20Research/ClinicalTrialsForms/Products/ConsumerInformation/Monographsand%20PublicAdvisories/Herceptin/herceptinSept14SIE.pdf.
-
Product monograph for Herceptin
-
-
-
82
-
-
0028884413
-
Requirement for neuroregulin receptor, erbB2, in neural and cardiac development
-
Lee K.S. Requirement for neuroregulin receptor, erbB2, in neural and cardiac development. Nature 1995, 379:394-396.
-
(1995)
Nature
, vol.379
, pp. 394-396
-
-
Lee, K.S.1
-
83
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
Carter P., Presta L., Gorman C.M., Ridgway J.B.B., Henner D., Wong W.L.T., et al. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci U S A 1992, 89:4285-4289.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 4285-4289
-
-
Carter, P.1
Presta, L.2
Gorman, C.M.3
Ridgway, J.B.B.4
Henner, D.5
Wong, W.L.T.6
-
84
-
-
84903807094
-
-
European Medicines Agency
-
European Medicines Agency Scientific Discussion on Herceptin http://www.ema.europa.eu/%20docs/en_GB/document_library/EPAR_-_Scientific_Discussion/human/000278/WC500049816.pdf.
-
Scientific Discussion on Herceptin
-
-
-
85
-
-
28344451882
-
Treatment of metastatic breast cancer with trastuzumab and vinorelbine during pregnancy
-
Fanale M.A., Uyei A.R., Theriault R.L., Adam K., Thompson R.A. Treatment of metastatic breast cancer with trastuzumab and vinorelbine during pregnancy. Clin Breast Cancer 2005, 6(4):354-356.
-
(2005)
Clin Breast Cancer
, vol.6
, Issue.4
, pp. 354-356
-
-
Fanale, M.A.1
Uyei, A.R.2
Theriault, R.L.3
Adam, K.4
Thompson, R.A.5
-
86
-
-
84903808448
-
-
European Medicines Agency
-
European Medicines Agency Assessment Report for Ipilimumab http://www.ema.europa.eu/%20docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/002213/WC500109302.pdf.
-
Assessment Report for Ipilimumab
-
-
-
87
-
-
84903798906
-
-
US Food and Drug Administration
-
US Food and Drug Administration Yervoy Prescribing INformation (Yervoy Label) http://www.accessdata.fda.gov/%20drugsatfda_docs/label/2011/125377s00001bl.pdf.
-
Yervoy Prescribing INformation (Yervoy Label)
-
-
-
88
-
-
0031405867
-
Lymphoproliferation in CTLA-4deficient mice is mediated by costimulation-dependent activation of CD4+ T cells
-
Chambers C.A., Sullivan T.J., Allison J.P. Lymphoproliferation in CTLA-4deficient mice is mediated by costimulation-dependent activation of CD4+ T cells. Immunity 1997, 7(6):885-895.
-
(1997)
Immunity
, vol.7
, Issue.6
, pp. 885-895
-
-
Chambers, C.A.1
Sullivan, T.J.2
Allison, J.P.3
-
89
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol E.A., Borriello F., Schweitzer A.N., et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995, 3(5):541-547.
-
(1995)
Immunity
, vol.3
, Issue.5
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
-
90
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
Waterhouse P., Penninger J.M., Timms E., et al. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 1995, 270(5238):985-988.
-
(1995)
Science
, vol.270
, Issue.5238
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
91
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
Egen J.G., Kuhns M.S., Allison J.P. CTLA-4: New insights into its biological function and use in tumor immunotherapy. Nat Immunol 2002, 3(7):611-618.
-
(2002)
Nat Immunol
, vol.3
, Issue.7
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
92
-
-
0027522107
-
Adverse effects of intravenous immunoglobulin
-
Misbah S.A., Chapel H.E. Adverse effects of intravenous immunoglobulin. Drug Safety 1993, 9(4):254-262.
-
(1993)
Drug Safety
, vol.9
, Issue.4
, pp. 254-262
-
-
Misbah, S.A.1
Chapel, H.E.2
-
93
-
-
5044225257
-
Anaphylaxis during anaesthesia:diagnosis and treatment
-
Soetens F.M. Anaphylaxis during anaesthesia:diagnosis and treatment. Acta Anaesthesiol Belg 2004, 55(4):229-237.
-
(2004)
Acta Anaesthesiol Belg
, vol.55
, Issue.4
, pp. 229-237
-
-
Soetens, F.M.1
-
94
-
-
0036552951
-
Allergic reactions occurring during anaesthesia
-
Mertes P.M., Laxenaire M.C. Allergic reactions occurring during anaesthesia. Eur J Anaesthesiol 2002, 19(4):240-262.
-
(2002)
Eur J Anaesthesiol
, vol.19
, Issue.4
, pp. 240-262
-
-
Mertes, P.M.1
Laxenaire, M.C.2
-
95
-
-
25144473457
-
Ischemic brain damage after ketamine and xylazine treatment in a young laboratory monkey (Macaca fascicularis)
-
Yoshizawa K., Oishi Y., Matsumoto M., Nyska A. Ischemic brain damage after ketamine and xylazine treatment in a young laboratory monkey (Macaca fascicularis). Contemp Top Lab Anim Sci 2005, 44(5):19-24.
-
(2005)
Contemp Top Lab Anim Sci
, vol.44
, Issue.5
, pp. 19-24
-
-
Yoshizawa, K.1
Oishi, Y.2
Matsumoto, M.3
Nyska, A.4
-
96
-
-
0017359978
-
Cardiovascular and respiratory responses to ketamine hydrochloride in the rhesus monkey (Macaca mulatta)
-
Ochsner A.J. Cardiovascular and respiratory responses to ketamine hydrochloride in the rhesus monkey (Macaca mulatta). Lab Anim Sci 1977, 27(1):69-71.
-
(1977)
Lab Anim Sci
, vol.27
, Issue.1
, pp. 69-71
-
-
Ochsner, A.J.1
-
97
-
-
33845660797
-
Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor infliximab
-
Bendtzen K., Geborek P., Svenson M., Larsson L., Kapetanovic M.C., Saxne T. Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor infliximab. Arthritis Rheum 2006, 54(12):3782-3789.
-
(2006)
Arthritis Rheum
, vol.54
, Issue.12
, pp. 3782-3789
-
-
Bendtzen, K.1
Geborek, P.2
Svenson, M.3
Larsson, L.4
Kapetanovic, M.C.5
Saxne, T.6
-
98
-
-
33751218879
-
Infusion reactions and their management
-
Mayer L., Young Y. Infusion reactions and their management. Gastroenterol Clin N Am 2006, 35:857-866.
-
(2006)
Gastroenterol Clin N Am
, vol.35
, pp. 857-866
-
-
Mayer, L.1
Young, Y.2
-
99
-
-
0346348142
-
Interferons in neurology
-
Aguilar Rebolledo F. Interferons in neurology. Rev Invest Clin 2000, 52:665-679.
-
(2000)
Rev Invest Clin
, vol.52
, pp. 665-679
-
-
Aguilar Rebolledo, F.1
-
100
-
-
0022632301
-
The preclinical development of Roferon-A
-
Trown P.W., Wills R.J., Kamm J.J. The preclinical development of Roferon-A. Cancer 1986, 57:1648-1656.
-
(1986)
Cancer
, vol.57
, pp. 1648-1656
-
-
Trown, P.W.1
Wills, R.J.2
Kamm, J.J.3
-
102
-
-
0000520727
-
Virus interference: I. The interferon
-
Isaacs A., Lindenmann J. Virus interference: I. The interferon. Proc R Soc Lond [B] 1957, 147:258-267.
-
(1957)
Proc R Soc Lond [B]
, vol.147
, pp. 258-267
-
-
Isaacs, A.1
Lindenmann, J.2
-
103
-
-
85031267634
-
Cell and virus sensitivitystudies with recombinant human alpha interferons
-
Kramer M.J., Dennin R., Kramer C., et al. Cell and virus sensitivitystudies with recombinant human alpha interferons. J Interferon Res 1983, 41:1-416.
-
(1983)
J Interferon Res
, vol.41
, pp. 1-416
-
-
Kramer, M.J.1
Dennin, R.2
Kramer, C.3
-
104
-
-
0019856859
-
Comparison of the antiviral activities of various cloned human interferon-a subtypes in mammalian cell cultures
-
Weck P.K., Apperson S., May L., Stebbing N. Comparison of the antiviral activities of various cloned human interferon-a subtypes in mammalian cell cultures. J Gen Virol 1981, 57:233-237.
-
(1981)
J Gen Virol
, vol.57
, pp. 233-237
-
-
Weck, P.K.1
Apperson, S.2
May, L.3
Stebbing, N.4
-
105
-
-
0020567041
-
Antiviral effects of bacteria-derived human leukocyte interferon against encephalomyocarditisvirus infection of squirrel monkeys
-
Stebbing N., Weck P.K., Fenno J.T., Estell D.A., Rinderknecht E. Antiviral effects of bacteria-derived human leukocyte interferon against encephalomyocarditisvirus infection of squirrel monkeys. Arch Virol 1983, 76(4):365-367.
-
(1983)
Arch Virol
, vol.76
, Issue.4
, pp. 365-367
-
-
Stebbing, N.1
Weck, P.K.2
Fenno, J.T.3
Estell, D.A.4
Rinderknecht, E.5
-
106
-
-
0020630492
-
In vivo antiviral activity of recombinant type a interferon A in monkeys with infections due to simian varicella virus
-
Soike K.F., Kramer M.J., Gerone P.J. In vivo antiviral activity of recombinant type a interferon A in monkeys with infections due to simian varicella virus. J Infect Dis 1983, 147:933-938.
-
(1983)
J Infect Dis
, vol.147
, pp. 933-938
-
-
Soike, K.F.1
Kramer, M.J.2
Gerone, P.J.3
-
107
-
-
85004973353
-
Effective treatment of a genital herpes simplex virus type 2 infection ofguinea pigs with recombinant human leukocyte A interferon
-
Kern E.R., Richards J.T., Overall J.C., Kramer M.J., Trown P.W. Effective treatment of a genital herpes simplex virus type 2 infection ofguinea pigs with recombinant human leukocyte A interferon. Proc 13th Int Cong Chemother 1983, 6:60/31-60/34.
-
(1983)
Proc 13th Int Cong Chemother
, vol.6
-
-
Kern, E.R.1
Richards, J.T.2
Overall, J.C.3
Kramer, M.J.4
Trown, P.W.5
-
108
-
-
0019946540
-
Human leukocyte interferon does not induce sister-chromatid exchanges in human blood lymphocytes
-
Vijayalaxmi
-
Vijayalaxmi Human leukocyte interferon does not induce sister-chromatid exchanges in human blood lymphocytes. Mutat Res 1982, 105:287-290.
-
(1982)
Mutat Res
, vol.105
, pp. 287-290
-
-
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