A comparative study on inhibition of total astragalus saponins and astragaloside IV on TNFR1-mediated signaling pathways in arterial endothelial cells

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Liu, Qin She ^a,b,c   Wang, Hai Fang ^b   Sun, An Ke ^d   Huo, Xue Ping ^b   Liu, Jin Lian ^a   Ma, Shu Hui ^a   Peng, Ning ^b   Hu, Jun ^b  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

^c Shaanxi Province Institute of Chinese Medicine and Medicinal Herbs   (China)

^d GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASTRAGALOSIDE II; ASTRAGALOSIDE III; ASTRAGALOSIDE IV; ASTRAGALUS SAPONIN; CASPASE 3; CELL ADHESION MOLECULE; CELL SURFACE PROTEIN; I KAPPA B ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; SAPONIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; ASTRAGALOSIDE A; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; I KAPPA B; INTERCELLULAR ADHESION MOLECULE 1; NF-KAPPAB INHIBITOR ALPHA; TRITERPENE;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTERIAL ENDOTHELIAL CELL; ARTICLE; CAM GENE; CELL SURFACE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; IMMUNOFLUORESCENCE; INHIBITION KINETICS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ARTERY; ASTRAGALUS (PLANT); CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION;

ANIMALS; APOPTOSIS; ARTERIES; ASTRAGALUS PLANT; CASPASE 3; CELLS, CULTURED; E-SELECTIN; ENDOTHELIAL CELLS; I-KAPPA B PROTEINS; INTERCELLULAR ADHESION MOLECULE-1; MICE; PHOSPHORYLATION; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SAPONINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84903795789     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101504     Document Type: Article

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