Statins protect human endothelial cells from TNF-induced inflammation via ERK5 activation

Biochemical Pharmacology

Volumn 85, Issue 12, 2013, Pages 1753-1760

  Wu, Ke ^a   Tian, Shiliu ^b   Zhou, Hillary ^c   Wu, Yong ^c  

^a WUHAN UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF SPORT   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Endothelial cells; ERK5; Inflammation; Reactive oxygen species; Statins; TNF

Indexed keywords

ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE 7; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; AORTA; ARTICLE; CELL MEMBRANE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN AORTIC ENDOTHELIAL CELL; HUMAN CELL; IMMUNE COMPLEX KINASE ASSAY; IMMUNOASSAY; INFLAMMATION; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

AORTA; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INFLAMMATION; MITOGEN-ACTIVATED PROTEIN KINASE 7; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878842316     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.04.009     Document Type: Article

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