von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor

Thrombosis and Haemostasis

Volumn 112, Issue 1, 2014, Pages 96-108

  Brehm, Maria A ^a   Huck, Volker ^d   Aponte Santamaría, Camilo ^c   Obser, Tobias ^a   Grässle, Sandra ^d   Oyen, Florian ^a   Budde, Ulrich ^b   Schneppenheim, Sonja ^b   Baldauf, Carsten ^e   Gräter, Frauke ^c   Schneider, Stefan W ^d   Schneppenheim, Reinhard ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b ASKLEPIOS KLINIK ALTONA   (Germany)

^c HEIDELBERG INSTITUTE FOR THEORETICAL STUDIES   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e FRITZ HABER INSTITUT DER MAX PLANCK GESELLSCHAFT   (Germany)

Author keywords

Microfluidic; Molecular dynamics simulations; Shear flow; von Willebrand factor; VWD

Indexed keywords

VON WILLEBRAND FACTOR;

AGAR GEL ELECTROPHORESIS; ARTICLE; BIOSYNTHESIS; CONFOCAL MICROSCOPY; DISULFIDE BOND; GENE EXPRESSION; GENE MUTATION; HUMAN; IMMUNOFLUORESCENCE TEST; MICROFLUIDIC ANALYSIS; MOLECULAR DYNAMICS; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; SHEAR STRESS; THROMBOCYTE AGGREGATION; VON WILLEBRAND DISEASE; CLASSIFICATION; DIMERIZATION; GENETICS; HEK293 CELL LINE; METABOLISM; MICROFLUIDICS; MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SHEAR STRENGTH; THROMBOCYTE;

BLOOD PLATELETS; DIMERIZATION; HEK293 CELLS; HUMANS; MICROFLUIDICS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; SHEAR STRENGTH; VON WILLEBRAND DISEASE, TYPE 2; VON WILLEBRAND FACTOR;

EID: 84903792599     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-11-0902     Document Type: Article

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