Local Elongation of Endothelial Cell-anchored von Willebrand Factor Strings Precedes ADAMTS13 Protein-mediated Proteolysis

Journal of Biological Chemistry

Volumn 286, Issue 42, 2011, Pages 36361-36367

  De Ceunynck, Karen ^a   Rocha, Susana ^a   Feys, Hendrik B ^a   De Meyer, Simon F ^a   Uji i, Hiroshi ^a   Deckmyn, Hans ^a   Hofkens, Johan ^a   Vanhoorelbeke, Karen ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE EVENTS; CLEAVAGE SITES; COMPUTING SOFTWARE; EXOSITES; FUNCTION OF TIME; LARGE ELONGATION; SPACE AND TIME; VON WILLEBRAND FACTOR;

ELONGATION;

ENDOTHELIAL CELLS;

VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ARTICLE; CELL ANCHORAGE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MOLECULAR SIZE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; RNA TRANSLATION;

ADAM PROTEINS; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; PROTEOLYSIS; VON WILLEBRAND FACTOR;

EID: 80054708189     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.271890     Document Type: Article

References (38)

1. Sadler, J. E. (1998) Annu. Rev. Biochem. 67, 395-424
2. Sadler, J. E. (2005) J. Thromb. Haemost. 3, 1702-1709
3. Ruggeri, Z. M. (2003) Curr. Opin. Hematol 10, 142-149
4. De Meyer, S. F., Deckmyn, H., and Vanhoorelbeke, K. (2009) Blood 113, 5049-5057
5. Sporn, L. A., Marder, V. J., and Wagner, D. D. (1986) Cell 46, 185-190
6. Moake, J. L., Rudy, C. K., Troll, J. H., Weinstein, M. J., Colannino, N. M., Azocar, J., Seder, R. H., Hong, S. L., and Deykin, D. (1982) N. Engl. J. Med. 307, 1432-1435
7. Tsai, H. M. (2007) Hematol. Oncol. Clin. North Am. 21, 609-632
8. Feys, H. B., Liu, F., Dong, N., Pareyn, I., Vauterin, S., Vandeputte, N., Noppe, W., Ruan, C., Deckmyn, H., and Vanhoorelbeke, K. (2006) J. Thromb. Haemost. 4, 955-962
9. Levy, G. G., Nichols, W. C., Lian, E. C., Foroud, T., McClintick, J. N., McGee, B. M., Yang, A. Y., Siemieniak, D. R., Stark, K. R., Gruppo, R., Sarode, R., Shurin, S. B., Chandrasekaran, V., Stabler, S. P., Sabio, H., Bouhassira, E. E., Upshaw, J. D., Jr., Ginsburg, D., and Tsai, H. M. (2001) Nature 413, 488-494
10. Tsai, H. M. (1996) Blood 87, 4235-4244
11. Furlan, M., Robles, R., and Lämmle, B. (1996) Blood 87, 4223-4234
12. Dong, J. F., Moake, J. L., Nolasco, L., Bernardo, A., Arceneaux, W., Shrimpton, C. N., Schade, A. J., McIntire, L. V., Fujikawa, K., and López, J. A. (2002) Blood 100, 4033-4039
13. Motto, D. G., Chauhan, A. K., Zhu, G., Homeister, J., Lamb, C. B., Desch, K. C., Zhang, W., Tsai, H. M., Wagner, D. D., and Ginsburg, D. (2005) J. Clin. Invest. 115, 2752-2761
14. Huang, J., Roth, R., Heuser, J. E., and Sadler, J. E. (2009) Blood 113, 1589-1597
15. Padilla, A., Moake, J. L., Bernardo, A., Ball, C., Wang, Y., Arya, M., Nolasco, L., Turner, N., Berndt, M. C., Anvari, B., López, J. A., and Dong, J. F. (2004) Blood 103, 2150-2156
16. Chauhan, A. K., Goerge, T., Schneider, S. W., and Wagner, D. D. (2007) J. Thromb. Haemost. 5, 583-589
17. Turner, N., Nolasco, L., Dong, J. F., and Moake, J. (2009) J. Thromb. Haemost. 7, 229-232
18. Turner, N. A., Nolasco, L., Ruggeri, Z. M., and Moake, J. L. (2009) Blood 114, 5102-5111
19. Lin, Y., Chang, L., Solovey, A., Healey, J. F., Lollar, P., and Hebbel, R. P. (2002) Blood 99, 457-462
20. De Meyer, S. F., Vanhoorelbeke, K., Chuah, M. K., Pareyn, I., Gillijns, V., Hebbel, R. P., Collen, D., Deckmyn, H., and VandenDriessche, T. (2006) Blood 107, 4728-4736
21. Feys, H. B., Anderson, P. J., Vanhoorelbeke, K., Majerus, E. M., and Sadler, J. E. (2009) J. Thromb. Haemost. 7, 2088-2095
22. Anderson, P. J., Kokame, K., and Sadler, J. E. (2006) J. Biol. Chem. 281, 850-857
23. Feys, H. B., Pareyn, I., Vancraenenbroeck, R., De Maeyer, M., Deckmyn, H., Van Geet, C., and Vanhoorelbeke, K. (2009) Blood 114, 4749-4752
24. Feys, H. B., Roodt, J., Vandeputte, N., Pareyn, I., Lamprecht, S., van Rensburg, W. J., Anderson, P. J., Budde, U., Louw, V. J., Badenhorst, P. N., Deckmyn, H., and Vanhoorelbeke, K. (2010) Blood 116, 2005-2010
25. van den Biggelaar, M., Bouwens, E. A., Kootstra, N. A., Hebbel, R. P., Voorberg, J., and Mertens, K. (2009) Haematologica 94, 670-678
26. Fowler, W. E., Fretto, L. J., Hamilton, K. K., Erickson, H. P., and McKee, P. A. (1985) J. Clin. Invest. 76, 1491-1500
27. Jin, S. Y., Skipwith, C. G., Shang, D., and Zheng, X. L. (2009) J. Thromb. Haemost. 7, 1749-1752
28. Zhang, X., Halvorsen, K., Zhang, C. Z., Wong, W. P., and Springer, T. A. (2009) Science 324, 1330-1334
29. Shim, K., Anderson, P. J., Tuley, E. A., Wiswall, E., and Sadler, J. E. (2008) Blood 111, 651-657
30. Suzuki, M., Murata, M., Matsubara, Y., Uchida, T., Ishihara, H., Shibano, T., Ashida, S., Soejima, K., Okada, Y., and Ikeda, Y. (2004) Biochem. Biophys. Res. Commun. 313, 212-216
31. Savage, B., Sixma, J. J., and Ruggeri, Z. M. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 425-430
32. Ulrichts, H., Vanhoorelbeke, K., Girma, J. P., Lenting, P. J., Vauterin, S., and Deckmyn, H. (2005) J. Thromb. Haemost. 3, 552-561
33. Li, Y., Choi, H., Zhou, Z., Nolasco, L., Pownall, H. J., Voorberg, J., Moake, J. L., and Dong, J. F. (2008) J. Thromb. Haemost. 6, 1135-1143
34. Wang, A., Liu, F., Dong, N., Ma, Z., Zhang, J., Su, J., Zhao, Y., and Ruan, C. (2010) Thromb. Res. 126, e260-e265
35. Bonnefoy, A., Daenens, K., Feys, H. B., De Vos, R., Vandervoort, P., Vermylen, J., Lawler, J., and Hoylaerts, M. F. (2006) Blood 107, 955-964
36. Zannettino, A. C., Holding, C. A., Diamond, P., Atkins, G. J., Kostakis, P., Farrugia, A., Gamble, J., To, L. B., Findlay, D. M., and Haynes, D. R. (2005) J. Cell Physiol. 204, 714-723
37. Huang, R. H., Wang, Y., Roth, R., Yu, X., Purvis, A. R., Heuser, J. E., Egelman, E. H., and Sadler, J. E. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 482-487
38. Michaux, G., Abbitt, K. B., Collinson, L. M., Haberichter, S. L., Norman, K. E., and Cutler, D. F. (2006) Dev. Cell 10, 223-232