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Volumn 27, Issue 7, 2014, Pages 958-971

Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP

(24)  Tzankov, Alexandar a,b   Xu Monette, Zijun Y a   Gerhard, Marc b   Visco, Carlo c   Dirnhofer, Stephan b   Gisin, Nora b   Dybkaer, Karen d   Orazi, Attilio e   Bhagat, Govind f   Richards, Kristy L g   Hsi, Eric D h   Choi, William W L i   Van Krieken, J Han j   Ponzoni, Maurilio k   Ferreri, Andrés J M k   Ye, Qing l   Winter, Jane N m   Farnen, John P n   Piris, Miguel A o   Møller, Michael B p   more..


Author keywords

diffuse large B cell lymphoma; FISH; germinal center B cell; MYC; prognosis; rearrangement; translocation

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; MYC PROTEIN; PREDNISONE; RITUXIMAB; VINCRISTINE; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

EID: 84903789487     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2013.214     Document Type: Article
Times cited : (112)

References (50)
  • 1
    • 69149089720 scopus 로고    scopus 로고
    • Diffuse large B-cell lymphoma, not otherwise specified
    • Swerdlow SC, Campo E, Harris NL, et al. (eds). IARC Press: Lyon, France
    • Stein H, Warnke RA, ChanWC, et al. Diffuse large B-cell lymphoma, not otherwise specified, In: Swerdlow SC, Campo E, Harris NL, et al. (eds) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press: Lyon, France; 2008, pp 233-237
    • (2008) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues , pp. 233-237
    • Stein, H.1    Warnke, R.A.2    Chan, W.C.3
  • 2
    • 77956933850 scopus 로고    scopus 로고
    • Pathogenesis of diffuse large B cell lymphoma
    • Chan WJ. Pathogenesis of diffuse large B cell lymphoma. Int J Hematol 2010;92: 219-230
    • (2010) Int J Hematol , vol.92 , pp. 219-230
    • Chan, W.J.1
  • 3
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000;403: 503-511
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 4
    • 0037142053 scopus 로고    scopus 로고
    • The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
    • Rosenwald A, Wright G, Chan WC, et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med 2002;346: 1937-1947
    • (2002) N Engl J Med , vol.346 , pp. 1937-1947
    • Rosenwald, A.1    Wright, G.2    Chan, W.C.3
  • 5
    • 0043192901 scopus 로고    scopus 로고
    • A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma
    • Wright G, Tan B, Rosenwald A, et al. A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma. Proc Natl Acad Sci USA 2003;100: 9991-9996
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9991-9996
    • Wright, G.1    Tan, B.2    Rosenwald, A.3
  • 6
    • 53749093794 scopus 로고    scopus 로고
    • Addition of rituximab to standard chemotherapy improves the survival of both the germinal center B-cell-like and non-germinal center B-cell-like subtypes of diffuse large B-cell lymphoma
    • Fu K, Weisenburger DD, Choi WW, et al. Addition of rituximab to standard chemotherapy improves the survival of both the germinal center B-cell-like and non-germinal center B-cell-like subtypes of diffuse large B-cell lymphoma. J Clin Oncol 2008;26: 4587-4594
    • (2008) J Clin Oncol , vol.26 , pp. 4587-4594
    • Fu, K.1    Weisenburger, D.D.2    Choi, W.W.3
  • 7
    • 60149087553 scopus 로고    scopus 로고
    • Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: A historical review of cytogenetics in the light of todays knowledge
    • Boerma EG, Siebert R, Kluin PM, et al. Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: A historical review of cytogenetics in the light of todays knowledge. Leukemia 2009;23: 225-234
    • (2009) Leukemia , vol.23 , pp. 225-234
    • Boerma, E.G.1    Siebert, R.2    Kluin, P.M.3
  • 8
    • 0032211147 scopus 로고    scopus 로고
    • Clinical relevance of BCL2 BCL6, and MYC rearrangements in diffuse large B-cell lymphoma
    • Kramer MH, Hermans J, Wijburg E, et al. Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma. Blood 1998;92: 3152-3162
    • (1998) Blood , vol.92 , pp. 3152-3162
    • Kramer, M.H.1    Hermans, J.2    Wijburg, E.3
  • 9
    • 70449589073 scopus 로고    scopus 로고
    • MYC gene rearrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy
    • Savage KJ, Johnson NA, Ben-Neriah S, et al. MYC gene rearrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy. Blood 2009;114: 3533-3537
    • (2009) Blood , vol.114 , pp. 3533-3537
    • Savage, K.J.1    Johnson, N.A.2    Ben-Neriah, S.3
  • 10
    • 57849149430 scopus 로고    scopus 로고
    • Structural aberrations affecting the myc locus indicate a poor prognosis independent of clinical risk factors in diffuse large b-cell lymphomas treated within rando-mized trials of the german high-grade non-hodgkin's lymphoma study group (dshnhl)
    • German High-Grade Non-Hodgkin's Lymphoma Study Group
    • Klapper W, Stoecklein H, Zeynalova S, et al. German High-Grade Non-Hodgkin's Lymphoma Study Group. Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within rando-mized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). Leukemia 2008; 22: 2226-2229
    • (2008) Leukemia , vol.22 , pp. 2226-2229
    • Klapper, W.1    Stoecklein, H.2    Zeynalova, S.3
  • 11
    • 64849083856 scopus 로고    scopus 로고
    • Clinical features and prognosis of de novo diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC translocations
    • Niitsu N, Okamoto M, Miura I, et al. Clinical features and prognosis of de novo diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC translocations. Leukemia 2009;23: 777-783
    • (2009) Leukemia , vol.23 , pp. 777-783
    • Niitsu, N.1    Okamoto, M.2    Miura, I.3
  • 12
    • 68149165799 scopus 로고    scopus 로고
    • Aberrations of the MYC gene in unselected cases of diffuse large B-cell lymphoma are rare and unpredictable by morphological or immunohistochemical assessment
    • Obermann EC, Csato M, Dirnhofer S, et al. Aberrations of the MYC gene in unselected cases of diffuse large B-cell lymphoma are rare and unpredictable by morphological or immunohistochemical assessment. J Clin Pathol 2009;62: 754-756
    • (2009) J Clin Pathol , vol.62 , pp. 754-756
    • Obermann, E.C.1    Csato, M.2    Dirnhofer, S.3
  • 13
    • 47749103376 scopus 로고    scopus 로고
    • MYC translocation and an increased copy number predict poor prognosis in adult diffuse large B-cell lymphoma (DLBCL), especially in germinal centre-like B cell (GCB) type
    • Yoon SO, Jeon YK, Paik JH, et al. MYC translocation and an increased copy number predict poor prognosis in adult diffuse large B-cell lymphoma (DLBCL), especially in germinal centre-like B cell (GCB) type. Histopathology 2008;53: 205-217
    • (2008) Histopathology , vol.53 , pp. 205-217
    • Yoon, S.O.1    Jeon, Y.K.2    Paik, J.H.3
  • 14
    • 70349575802 scopus 로고    scopus 로고
    • Lymphomas with concurrent BCL2 and MYC translocations: The critical factors associated with survival
    • Johnson NA, Savage KJ, Ludkovski O, et al. Lymphomas with concurrent BCL2 and MYC translocations: The critical factors associated with survival. Blood 2009;114: 2273-2279
    • (2009) Blood , vol.114 , pp. 2273-2279
    • Johnson, N.A.1    Savage, K.J.2    Ludkovski, O.3
  • 15
    • 0842343475 scopus 로고    scopus 로고
    • Coexistent rearrangements of c-MYC, BCL2, and BCL6 genes in a diffuse large B-cell lymphoma
    • Ueda C, Nishikori M, Kitawaki T, et al. Coexistent rearrangements of c-MYC, BCL2, and BCL6 genes in a diffuse large B-cell lymphoma. Int J Hematol 2004; 79: 52-54
    • (2004) Int J Hematol , vol.79 , pp. 52-54
    • Ueda, C.1    Nishikori, M.2    Kitawaki, T.3
  • 16
    • 79952154009 scopus 로고    scopus 로고
    • Double-hit B-cell lymphomas
    • Aukema SM, Siebert R, Schuuring E, et al. Double-hit B-cell lymphomas. Blood 2011;117: 2319-2331
    • (2011) Blood , vol.117 , pp. 2319-2331
    • Aukema, S.M.1    Siebert, R.2    Schuuring, E.3
  • 17
    • 79955096411 scopus 로고    scopus 로고
    • MYC and aggressive B-cell lymphomas
    • Slack GW, Gascoyne RD. MYC and aggressive B-cell lymphomas. Adv Anat Pathol 2011;18: 219-228
    • (2011) Adv Anat Pathol , vol.18 , pp. 219-228
    • Slack, G.W.1    Gascoyne, R.D.2
  • 18
    • 84867060272 scopus 로고    scopus 로고
    • Immunohistochemical double-hit score is a strong predictor of outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone
    • Green TM, Young KH, Visco C, et al. Immunohistochemical double-hit score is a strong predictor of outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol 2012;30: 3460-3467
    • (2012) J Clin Oncol , vol.30 , pp. 3460-3467
    • Green, T.M.1    Young, K.H.2    Visco, C.3
  • 19
    • 84879385620 scopus 로고    scopus 로고
    • MYC/BCL2 protein co-expression associated with high-risk gene signatures contributes to the inferior prognosis of activated B-cell subtype of DLBCL
    • Hu S, Xu-Monette ZY, Tzankov A, et al. MYC/BCL2 protein co-expression associated with high-risk gene signatures contributes to the inferior prognosis of activated B-cell subtype of DLBCL. Blood 2013;121: 4021-4031
    • (2013) Blood , vol.121 , pp. 4021-4031
    • Hu, S.1    Xu-Monette, Z.Y.2    Tzankov, A.3
  • 20
    • 84865339813 scopus 로고    scopus 로고
    • Prognostic significance of MYC, BCL2 and BCL6 rearrangements in patients with diffuse large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone plus rituximab
    • Akyurek N, Uner A, Benekli M, et al. Prognostic significance of MYC, BCL2 and BCL6 rearrangements in patients with diffuse large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone plus rituximab. Cancer 2012;118: 4173-4183
    • (2012) Cancer , vol.118 , pp. 4173-4183
    • Akyurek, N.1    Uner, A.2    Benekli, M.3
  • 21
    • 84867088456 scopus 로고    scopus 로고
    • Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone
    • Johnson NA, Slack GW, Savage KJ, et al. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol 2012;30: 3452-3459
    • (2012) J Clin Oncol , vol.30 , pp. 3452-3459
    • Johnson, N.A.1    Slack, G.W.2    Savage, K.J.3
  • 22
    • 33947496614 scopus 로고    scopus 로고
    • International Harmonization Project on Lymphoma. Revised response criteria for malignant lymphoma
    • Cheson BD, Pfistner B, Juweid ME, et al. International Harmonization Project on Lymphoma. Revised response criteria for malignant lymphoma. J Clin Oncol 2007;25: 579-586
    • (2007) J Clin Oncol , vol.25 , pp. 579-586
    • Cheson, B.D.1    Pfistner, B.2    Juweid, M.E.3
  • 23
    • 70349687436 scopus 로고    scopus 로고
    • BCL2 gene aberration as an IPI-independent marker for poor outcome in non-germinal-centre diffuse large B cell lymphoma
    • Obermann EC, Csato M, Dirnhofer S, et al. BCL2 gene aberration as an IPI-independent marker for poor outcome in non-germinal-centre diffuse large B cell lymphoma. J Clin Pathol 2009;62: 903-907
    • (2009) J Clin Pathol , vol.62 , pp. 903-907
    • Obermann, E.C.1    Csato, M.2    Dirnhofer, S.3
  • 24
    • 66549127133 scopus 로고    scopus 로고
    • Prognostic importance of BCL6 rearrangements in diffuse large B-cell lymphoma with respect to Bcl6 protein levels and primary lymphoma site
    • Tzankov A, Schneider A, Hoeller S, et al. Prognostic importance of BCL6 rearrangements in diffuse large B-cell lymphoma with respect to Bcl6 protein levels and primary lymphoma site. Hum Pathol 2009;40: 1055-1056
    • (2009) Hum Pathol , vol.40 , pp. 1055-1056
    • Tzankov, A.1    Schneider, A.2    Hoeller, S.3
  • 25
    • 76349113374 scopus 로고    scopus 로고
    • Prognostic immunophenotypic biomarker studies in diffuse large B cell lymphoma with special emphasis on rational determination of cut-off scores
    • Tzankov A, Zlobec I, Went P, et al. Prognostic immunophenotypic biomarker studies in diffuse large B cell lymphoma with special emphasis on rational determination of cut-off scores. Leuk Lymphoma 2010; 51: 199-212
    • (2010) Leuk Lymphoma , vol.51 , pp. 199-212
    • Tzankov, A.1    Zlobec, I.2    Went, P.3
  • 26
    • 84875314276 scopus 로고    scopus 로고
    • BCL2 rearrangement characterizes a subset of patients with diffuse large B cell lymphoma of germinal center origin with poor outcome: A report from an international DLBCL rituximab-CHOP consortium program study
    • Visco C, Tzankov A, Xu-Monette ZY, et al. BCL2 rearrangement characterizes a subset of patients with diffuse large B cell lymphoma of germinal center origin with poor outcome: A report from an international DLBCL rituximab-CHOP consortium program study. Haematologica 2013;98: 255-263
    • (2013) Haematologica , vol.98 , pp. 255-263
    • Visco, C.1    Tzankov, A.2    Xu-Monette, Z.Y.3
  • 27
    • 84865865930 scopus 로고    scopus 로고
    • Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large b-cell lymphoma: A report from the international dlbcl rituximab-chop consortium program study
    • Visco C, Li Y, Xu-Monette ZY, et al. Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: A report from the International DLBCL Rituximab-CHOP Consortium Program Study. Leukemia 2012;26: 2103-2113
    • (2012) Leukemia , vol.26 , pp. 2103-2113
    • Visco, C.1    Li, Y.2    Xu-Monette, Z.Y.3
  • 28
    • 23644432019 scopus 로고    scopus 로고
    • Statistics subcommittee of the nci-eortc working group on cancer diagnostics reporting recommendations for tumour marker prognostic studies (remark
    • McShane LM, Altman DG, Sauerbrei W, et al. Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. REporting recommendations for tumour MARKer prognostic studies (REMARK). Eur J Cancer 2005;41: 1690-1696
    • (2005) Eur J Cancer , vol.41 , pp. 1690-1696
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 29
    • 42649113874 scopus 로고    scopus 로고
    • Prognostic significance of maximum tumour (bulk) diameter in young patients with good-prognosis diffuse large-bcell lymphoma treated with chop-like chemotherapy with or without rituximab: An exploratory analysis of the mabthera international trial group (mint) study
    • MabThera International Trial (MInT) Group
    • Pfreundschuh M, Ho AD, Cavallin-Stahl E, et al. MabThera International Trial (MInT) Group. Prognostic significance of maximum tumour (bulk) diameter in young patients with good-prognosis diffuse large-Bcell lymphoma treated with CHOP-like chemotherapy with or without rituximab: An exploratory analysis of the MabThera International Trial Group (MInT) study. Lancet Oncol 2008;9: 435-444
    • (2008) Lancet Oncol , vol.9 , pp. 435-444
    • Pfreundschuh, M.1    Ho, A.D.2    Cavallin-Stahl, E.3
  • 30
    • 33847190348 scopus 로고    scopus 로고
    • Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas
    • Bertrand P, Bastard C, Maingonnat C, et al. Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas. Leukemia 2007;21: 515-523
    • (2007) Leukemia , vol.21 , pp. 515-523
    • Bertrand, P.1    Bastard, C.2    Maingonnat, C.3
  • 31
    • 43749093885 scopus 로고    scopus 로고
    • Characterization of three t(3;8)(q27;q24) translocations from diffuse large B-cell lymphomas
    • Bertrand P, Maingonnat C, Picquenot JM, et al. Characterization of three t(3;8)(q27;q24) translocations from diffuse large B-cell lymphomas. Leukemia 2008;22: 1064-1067
    • (2008) Leukemia , vol.22 , pp. 1064-1067
    • Bertrand, P.1    Maingonnat, C.2    Picquenot, J.M.3
  • 32
    • 33845507107 scopus 로고    scopus 로고
    • A novel t(3;8) (q27;q24.1) simultaneously involving both the BCL6 and MYC genes in a diffuse large B-cell lymphoma
    • Wang HY, Bossler AD, Schaffer A, et al. A novel t(3;8) (q27;q24.1) simultaneously involving both the BCL6 and MYC genes in a diffuse large B-cell lymphoma. Cancer Genet Cytogenet 2007;172: 45-53
    • (2007) Cancer Genet Cytogenet , vol.172 , pp. 45-53
    • Wang, H.Y.1    Bossler, A.D.2    Schaffer, A.3
  • 33
    • 0025907718 scopus 로고
    • Patterns of chromosomal breakpoint locations in Burkitt's lymphoma: Relevance to geography and Epstein-Barr virus association
    • Shiramizu B, Barriga F, Neequaye J, et al. Patterns of chromosomal breakpoint locations in Burkitt's lymphoma: Relevance to geography and Epstein-Barr virus association. Blood 1991;77: 1516-1526
    • (1991) Blood , vol.77 , pp. 1516-1526
    • Shiramizu, B.1    Barriga, F.2    Neequaye, J.3
  • 34
    • 0142233513 scopus 로고
    • Chromosomal breakpoints and structural alterations of the c-myc locus differ in endemic and sporadic forms of Burkitt lymphoma
    • Pelicci PG, Knowles DM 2nd, Magrath I, et al. Chromosomal breakpoints and structural alterations of the c-myc locus differ in endemic and sporadic forms of Burkitt lymphoma. Proc Natl Acad Sci USA 1986;83: 2984-2988
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2984-2988
    • Pelicci, P.G.1    Knowles II, D.M.2    Magrath, I.3
  • 35
    • 0038185378 scopus 로고    scopus 로고
    • Genomic targets of the human c-Myc protein
    • Fernandez PC, Frank SR, Wang L, et al. Genomic targets of the human c-Myc protein. Genes Dev 2003;17: 1115-1129
    • (2003) Genes Dev , vol.17 , pp. 1115-1129
    • Fernandez, P.C.1    Frank, S.R.2    Wang, L.3
  • 36
    • 34648813265 scopus 로고    scopus 로고
    • Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia
    • Kainz B, Shehata M, Bilban M, et al. Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia. Int J Cancer 2007;121: 1984-1993
    • (2007) Int J Cancer , vol.121 , pp. 1984-1993
    • Kainz, B.1    Shehata, M.2    Bilban, M.3
  • 37
    • 84865339813 scopus 로고    scopus 로고
    • Prognostic significance of MYC, BCL2, and BCL6 rearrangements in patients with diffuse large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone plus rituximab
    • Akyurek N, Uner A, Benekli M, et al. Prognostic significance of MYC, BCL2, and BCL6 rearrangements in patients with diffuse large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone plus rituximab. Cancer 2012;118: 4173-4183
    • (2012) Cancer , vol.118 , pp. 4173-4183
    • Akyurek, N.1    Uner, A.2    Benekli, M.3
  • 38
    • 73949137883 scopus 로고    scopus 로고
    • Immunofluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: A GELA study
    • Copie-Bergman C, Gaulard P, Leroy K, et al. Immunofluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: A GELA study. J Clin Oncol 2009;27: 5573-5579
    • (2009) J Clin Oncol , vol.27 , pp. 5573-5579
    • Copie-Bergman, C.1    Gaulard, P.2    Leroy, K.3
  • 39
    • 77954752069 scopus 로고    scopus 로고
    • Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab
    • Barrans S, Crouch S, Smith A, et al. Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab. J Clin Oncol 2010;28: 3360-3365
    • (2010) J Clin Oncol , vol.28 , pp. 3360-3365
    • Barrans, S.1    Crouch, S.2    Smith, A.3
  • 40
    • 84861211721 scopus 로고    scopus 로고
    • MYC diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation
    • Cuccuini W, Briere J, Mounier N, et al. MYC diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation. Blood 2012;119: 4619-4624
    • (2012) Blood , vol.119 , pp. 4619-4624
    • Cuccuini, W.1    Briere, J.2    Mounier, N.3
  • 41
    • 64049093008 scopus 로고    scopus 로고
    • BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: A multicenter evaluation of a new set of fluorescent in situ hybridization probes and correlation with clinical outcome
    • Tibiletti MG, Martin V, Bernasconi B, et al. BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: A multicenter evaluation of a new set of fluorescent in situ hybridization probes and correlation with clinical outcome. Hum Pathol 2009;40: 645-652
    • (2009) Hum Pathol , vol.40 , pp. 645-652
    • Tibiletti, M.G.1    Martin, V.2    Bernasconi, B.3
  • 42
    • 0036772195 scopus 로고    scopus 로고
    • Detection of three common translocation breakpoints in non-Hodgkin's lymphomas by fluorescence in situ hybridization on routine paraffin-embedded tissue sections
    • Haralambieva E, Kleiverda K, Mason DY, et al. Detection of three common translocation breakpoints in non-Hodgkin's lymphomas by fluorescence in situ hybridization on routine paraffin-embedded tissue sections. J Pathol 2002;198: 163-170
    • (2002) J Pathol , vol.198 , pp. 163-170
    • Haralambieva, E.1    Kleiverda, K.2    Mason, D.Y.3
  • 43
    • 80054917818 scopus 로고    scopus 로고
    • Immunohistochemical detection of MYC protein correlates with MYC gene status in aggressive B cell lymphomas
    • Tapia G, Lopez R, Munöz-Mármol AM, et al. Immunohistochemical detection of MYC protein correlates with MYC gene status in aggressive B cell lymphomas. Histopathology 2011;59: 672-678
    • (2011) Histopathology , vol.59 , pp. 672-678
    • Tapia, G.1    Lopez, R.2    Munöz-Mármol, A.M.3
  • 44
    • 84867083287 scopus 로고    scopus 로고
    • Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas
    • Kluk MJ, Chapuy B, Sinha P, et al. Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas. PLoS One 2012;7: 1-9
    • (2012) PLoS One , vol.7 , pp. 1-9
    • Kluk, M.J.1    Chapuy, B.2    Sinha, P.3
  • 45
    • 57149097456 scopus 로고    scopus 로고
    • MYC translocationnegative classical Burkitt lymphoma cases: An alternative pathogenetic mechanism involving miRNA deregulation
    • Leucci E, Cocco M, Onnis A, et al. MYC translocationnegative classical Burkitt lymphoma cases: An alternative pathogenetic mechanism involving miRNA deregulation. J Pathol 2008;216: 440-450
    • (2008) J Pathol , vol.216 , pp. 440-450
    • Leucci, E.1    Cocco, M.2    Onnis, A.3
  • 46
    • 79959387359 scopus 로고    scopus 로고
    • Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1
    • Craig VJ, Cogliatti SB, Imig J, et al. Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1. Blood 2011;117: 6227-6236
    • (2011) Blood , vol.117 , pp. 6227-6236
    • Craig, V.J.1    Cogliatti, S.B.2    Imig, J.3
  • 47
    • 79959248268 scopus 로고    scopus 로고
    • Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia
    • Bonnet M, Loosveld M, Montpellier B, et al. Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia. Blood 2011; 117: 6650-6659
    • (2011) Blood , vol.117 , pp. 6650-6659
    • Bonnet, M.1    Loosveld, M.2    Montpellier, B.3
  • 48
    • 84855281681 scopus 로고    scopus 로고
    • Myc agressive B-cell lymphomas: Novel therapy of untreated Burkitt lymphoma (BL) and Myc diffuse large B-cell lymphoma (DLBCL) with DA-EPOCH-R
    • Dunleavy K, Pittaluga S, Wayne S, et al. Myc agressive B-cell lymphomas: Novel therapy of untreated Burkitt lymphoma (BL) and Myc diffuse large B-cell lymphoma (DLBCL) with DA-EPOCH-R. Ann Oncol 2011;22(Suppl 4): 071
    • (2011) Ann Oncol , vol.22 , Issue.SUPPL. 4 , pp. 071
    • Dunleavy, K.1    Pittaluga, S.2    Wayne, S.3
  • 49
    • 84875422081 scopus 로고    scopus 로고
    • Potassium channels: Novel emerging biomarkers and targets for therapy in cancer
    • D'Amico M, Gasparoli L, Arcangeli A. Potassium channels: Novel emerging biomarkers and targets for therapy in cancer. Recent Pat Anticancer Drug Discov 2013;8: 53-65
    • (2013) Recent Pat Anticancer Drug Discov , vol.8 , pp. 53-65
    • D'Amico, M.1    Gasparoli, L.2    Arcangeli, A.3
  • 50
    • 29844437655 scopus 로고    scopus 로고
    • International union of pharmacology liii nomenclature and molecular relationships of voltage-gated potassium channels
    • Gutman GA, Chandy KG, Grissmer S, et al. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev 2005;57: 473-508
    • (2005) Pharmacol Rev , vol.57 , pp. 473-508
    • Gutman, G.A.1    Chandy, K.G.2    Grissmer, S.3


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