Activation of the Pi3k/Akt pathway and modulation of phosphodiesterase activity via membrane progestin receptor-alpha (mPRalpha) regulate progestin-initiated sperm hypermotility in Atlantic croaker

Biology of Reproduction

Volumn 90, Issue 5, 2014, Pages

  Tan, Wenxian ^a   Thomas, Peter ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

20b S; Akt; cAMP; Membrane progestin receptor; Org Od 02 0; Phosphodiesterase; Pi3k; Progestins; Sperm hypermotility

Indexed keywords

ADENYLATE CYCLASE; CALCIUM CHANNEL; CILOSTAMIDE; CYCLIC AMP; GESTAGEN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MEMBRANE PROGESTIN RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN KINASE B; ROLIPRAM; UNCLASSIFIED DRUG; WORTMANNIN; 1 (5 CHLORO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANDROSTANE DERIVATIVE; AZEPINE DERIVATIVE; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; QUINOLONE DERIVATIVE;

ACROSOME REACTION; ADULT; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPERM HYPERMOTILITY; SPERMATOZOON MOTILITY; TELEOST; AGONISTS; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; MALE; METABOLISM; PERCIFORMES; PHYSIOLOGY; SPERMATOZOON; VETERINARY; WESTERN BLOTTING;

ANDROSTADIENES; ANIMALS; AZEPINES; BLOTTING, WESTERN; CHROMONES; ENZYME ACTIVATION; MALE; MORPHOLINES; PERCIFORMES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORIC DIESTER HYDROLASES; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLONES; RECEPTORS, PROGESTERONE; ROLIPRAM; SIGNAL TRANSDUCTION; SPERM MOTILITY; SPERMATOZOA;

EID: 84903782213     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.112896     Document Type: Article

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