Mixed Mycobacterium tuberculosis complex infections and false-negative results for rifampin resistance by genexpert MTB/RIF are associated with poor clinical outcomes

Journal of Clinical Microbiology

Volumn 52, Issue 7, 2014, Pages 2422-2429

  Zetola, Nicola M ^a,c,d   Shin, Sanghyuk S ^g   Tumedi, Kefentse A ^a   Moeti, Keletso ^b   Ncube, Ronald ^e   Nicol, Mark ^f   Collman, Ronald G ^c   Klausner, Jeffrey D ^g   Modongoa, Chawangwa ^a,c  

^a BOTSWANA UPENN PARTNERSHIP   (Botswana)

^b National Health Laboratory   (Botswana)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF BOTSWANA   (Botswana)

^e Department of HIV AIDS Prevention and Care   (Botswana)

^f UNIVERSITY OF CAPE TOWN   (South Africa)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMPICIN; TUBERCULOSTATIC AGENT;

ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; GENE LOCUS; GENOTYPE PHENOTYPE CORRELATION; HUMAN; IN VITRO STUDY; INTERSPERSED REPEAT; LIMIT OF DETECTION; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS TEST KIT; NONHUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SPUTUM ANALYSIS; STRAIN IDENTIFICATION; TUBERCULOSIS; TUBERCULOSIS RAPID TEST; VARIABLE NUMBER OF TANDEM REPEAT; YOUNG ADULT; AGED; COHORT ANALYSIS; COINFECTION; DRUG EFFECTS; ISOLATION AND PURIFICATION; LABORATORY DIAGNOSIS; MICROBIAL SENSITIVITY TEST; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MIDDLE AGED; MOLECULAR DIAGNOSIS; PROCEDURES; RETROSPECTIVE STUDY; TREATMENT OUTCOME; TUBERCULOSIS, MULTIDRUG-RESISTANT; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTITUBERCULAR AGENTS; BACTERIOLOGICAL TECHNIQUES; COHORT STUDIES; COINFECTION; DRUG RESISTANCE, BACTERIAL; FALSE NEGATIVE REACTIONS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR DIAGNOSTIC TECHNIQUES; MYCOBACTERIUM TUBERCULOSIS; RETROSPECTIVE STUDIES; RIFAMPIN; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; TUBERCULOSIS, MULTIDRUG-RESISTANT; YOUNG ADULT;

EID: 84903764046     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.02489-13     Document Type: Article

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