Rapid, high-throughput detection of rifampin resistance and heteroresistance in Mycobacterium tuberculosis by use of sloppy molecular beacon melting temperature coding

Journal of Clinical Microbiology

Volumn 50, Issue 7, 2012, Pages 2194-2202

  Chakravorty, Soumitesh ^a   Kothari, Harsheel ^a   Aladegbami, Bola ^a,f   Cho, Eun Jin ^b   Lee, Jong Seok ^b   Roh, Sandy S ^a   Kim, Hyunchul ^b   Kwak, Hyungkyung ^b   Lee, Eun Gae ^c,g   Hwang, Soo Hee ^d   Banada, Padmapriya P ^a   Safi, Hassan ^a   Via, Laura E ^c   Cho, Sang Nae ^b,e   Barry III, Clifton E ^c   Alland, David ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b International Tuberculosis Research Center   (South Korea)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d National Masan Tuberculosis Hospital   (South Korea)

^e Yonsei University   (South Korea)

^f STONY BROOK UNIVERSITY   (United States)

^g Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; OLIGONUCLEOTIDE; RIFAMPICIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; ASSAY; BACTERIAL GENE; BACTERIUM CULTURE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA EXTRACTION; DNA SEQUENCE; GENE CLUSTER; HIGH THROUGHPUT SCREENING; HUMAN; LIMIT OF DETECTION; MICROBIAL DIVERSITY; MUTATIONAL ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RIFAMPICIN RESISTANCE DETERMINING REGION; RPOB GENE; SENSITIVITY AND SPECIFICITY; SLOPPY MOLECULAR BEACON ASSAY;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR DIAGNOSTIC TECHNIQUES; MYCOBACTERIUM TUBERCULOSIS; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; RIFAMPIN; SENSITIVITY AND SPECIFICITY; TIME FACTORS; TRANSITION TEMPERATURE; TUBERCULOSIS;

EID: 84862743936     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00143-12     Document Type: Article

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