Inbreeding coefficient estimation with dense SNP data: Comparison of strategies and application to HapMap III

Human Heredity

Volumn 77, Issue 1-4, 2014, Pages 49-62

  Gazal, Steven ^a,b   Sahbatou, Mourad ^c   Perdry, Hervé ^b,d   Letort, Sébastien ^e,f   Génin, Emmanuelle ^e,f   Leutenegger, Anne Louise ^a,g  

^a INSERM   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c FONDATION JEAN DAUSSET CEPH   (France)

^d Universite Paris Sud   (France)

^e French Blood Agency   (France)

^f UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^g UNIVERSITÉ PARIS DIDEROT   (France)

Author keywords

HapMap III; Hidden Markov model; Homozygosity by descent; Inbreeding; Linkage disequilibrium; Run of homozygosity

Indexed keywords

ACCURACY; ARTICLE; CHROMOSOME 11; CONSANGUINITY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENEALOGY; GENETIC PARAMETERS; HAPLOTYPE; HAPLOTYPE MAP; HIDDEN MARKOV MODEL; HOMOZYGOSITY; HUMAN; INBREEDING; NBREEDING COEFFICIENT ESTIMATION; PEDIGREE ANALYSIS; PROGENY; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETICS; POPULATION GENETICS; STATISTICAL MODEL; CONTROLLED STUDY; GENE LOCUS; GENE MAPPING; GENETIC DISTANCE; GENETIC MODEL; GENOTYPE; HETEROZYGOSITY; MAJOR CLINICAL STUDY;

COMPUTER SIMULATION; CONSANGUINITY; GENETICS, POPULATION; HAPLOTYPES; HAPMAP PROJECT; HUMANS; LIKELIHOOD FUNCTIONS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84903748318     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000358224     Document Type: Article

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