Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 9, 2014, Pages 2970-2977

  Wu, Yue ^a   Zan, Li Peng ^a   Wang, Xiao Dong ^a   Lu, Yu Jing ^b   Ou, Tian Miao ^a   Lin, Jing ^a   Huang, Zhi Shu ^a   Gu, Lian Quan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGDONG UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Angiogenesis; Anti tumor; G quadruplex; Quindoline derivative; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; QUINDOLINE DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL SCRAPE TEST; CHICK EMBRYO CHORIOALLANTOIC MEMBRANE ASSAY; CIRCULAR DICHROISM; COMPLEX FORMATION; DNA SEQUENCE; DRUG DETERMINATION; DRUG DNA INTERACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; PCR STOP ASSAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TRANSCRIPTION REGULATION;

ANGIOGENESIS; ANTI-TUMOR; G-QUADRUPLEX; QUINDOLINE DERIVATIVE; VEGF;

ALKALOIDS; ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHICK EMBRYO; CIRCULAR DICHROISM; CPG ISLANDS; HUMANS; INDOLES; LIGANDS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PROMOTER REGIONS, GENETIC; QUINOLINES; TRANSCRIPTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84903698085     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.06.002     Document Type: Article

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